Superoxide radicals increase transforming growth factor-β1 and collagen release from human lung fibroblasts via cellular influx through chloride channels

Toxicology and Applied Pharmacology

Volumn 237, Issue 1, 2009, Pages 111-118

  Qi, Shufan ^a   den Hartog, Gertjan J M ^a   Bast, Aalt ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Chloride channels; Collagen; Human lung fibroblasts; MAPKs; Superoxide; TGF 1

Indexed keywords

CATALASE; CHLORIDE CHANNEL; COLLAGEN; GLUTATHIONE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TEMPOL; TRANSFORMING GROWTH FACTOR BETA1; XANTHINE; XANTHINE OXIDASE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL VIABILITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROGENESIS; HUMAN; HUMAN CELL; IMMUNOASSAY; LUNG FIBROBLAST; LUNG FIBROSIS; PATHOGENESIS;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; APOPTOSIS; BIOLOGICAL MARKERS; CASPASE 3; CELL LINE; CELL SURVIVAL; CHLORIDE CHANNELS; COLLAGEN; FEMALE; FIBROBLASTS; HUMANS; LUNG; OXIDATIVE STRESS; PULMONARY FIBROSIS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; SUPEROXIDES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 67349134153     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.02.019     Document Type: Article

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