-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin 2008;58:71-96.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
0035165047
-
Gemcitabine: Progress in the treatment of pancreatic cancer
-
DOI 10.1159/000055290
-
Heinemann V. Gemcitabine: progress in the treatment of pancreatic cancer. Oncology 2001;60:8-18. (Pubitemid 32041425)
-
(2001)
Oncology
, vol.60
, Issue.1
, pp. 8-18
-
-
Heinemann, V.1
-
3
-
-
0030870485
-
Gemcitabine. A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer
-
Noble S, Goa KL. Gemcitabine. A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer. Drugs 1997;54:447-72.
-
(1997)
Drugs
, vol.54
, pp. 447-472
-
-
Noble, S.1
Goa, K.L.2
-
4
-
-
0033638288
-
The role of gemcitabine alone and in combination in the treatment of pancreatic cancer
-
Oettle H, Arnold D, Hempel C, Riess H. The role of gemcitabine alone and in combination in the treatment of pancreatic cancer. Anticancer Drugs 2000;11:771-86.
-
(2000)
Anticancer Drugs
, vol.11
, pp. 771-786
-
-
Oettle, H.1
Arnold, D.2
Hempel, C.3
Riess, H.4
-
5
-
-
0019410935
-
Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil. The gastrointestinal tumor study group
-
DOI 10.1002/1097-0142(19811015)48:8<1705::AID-CNCR2820480803>3.0. CO;2-4
-
Moertel CG, Frytak S, Hahn RG, et al. Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group. Cancer 1981;48:1705-10. (Pubitemid 11022870)
-
(1981)
Cancer
, vol.48
, Issue.8
, pp. 1705-1710
-
-
Moertel, C.G.1
Frytak, S.2
Hahn, R.G.3
-
6
-
-
0031900378
-
Seventy-two hour epirubicin infusion plus quinidine in unresectable and metastatic adenocarcinoma of the pancreas: A phase II trial
-
Abad A, Massuti B, Blanco E, et al. Seventy-two hour epirubicin infusion plus quinidine in unresectable and metastatic adenocarcinoma of the pancreas: a phase II trial. Am J Clin Oncol 1998;21:151-4.
-
(1998)
Am J Clin Oncol
, vol.21
, pp. 151-154
-
-
Abad, A.1
Massuti, B.2
Blanco, E.3
-
7
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
Burris HA III, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-13.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
-
8
-
-
16244413613
-
Phase II trial of oral rubitecan in previously treated pancreatic cancer patients
-
Burris HA III, Rivkin S, Reynolds R, et al. Phase II trial of oral rubitecan in previously treated pancreatic cancer patients. Oncologist 2005;10:183-90.
-
(2005)
Oncologist
, vol.10
, pp. 183-190
-
-
Burris III, H.A.1
Rivkin, S.2
Reynolds, R.3
-
9
-
-
0034982982
-
Gemcitabine in advanced pancreatic cancer: A phase II trial
-
Crino L, Mosconi AM, Calandri C, et al. Gemcitabine in advanced pancreatic cancer: a phase II trial. Am J Clin Oncol 2001;24:296-8.
-
(2001)
Am J Clin Oncol
, vol.24
, pp. 296-298
-
-
Crino, L.1
Mosconi, A.M.2
Calandri, C.3
-
10
-
-
4644257764
-
Phase II clinical trial of 5-fluorouracil, trimetrexate, and leucovorin (NFL) in patients with advanced pancreatic cancer
-
Garcia AA, Leichman L, Baranda J, Pandit L, Lenz HJ, Leichman CG. Phase II clinical trial of 5-fluorouracil, trimetrexate, and leucovorin (NFL) in patients with advanced pancreatic cancer. Int J Gastrointest Cancer 2003;34:79-86.
-
(2003)
Int J Gastrointest Cancer
, vol.34
, pp. 79-86
-
-
Garcia, A.A.1
Leichman, L.2
Baranda, J.3
Pandit, L.4
Lenz, H.J.5
Leichman, C.G.6
-
11
-
-
2942532599
-
Treatment of metastatic pancreatic cancer with a combination of gemcitabine and 5-fluorouracil: A single center phase II study
-
Kanat O, Evrensel T, Kurt E, et al. Treatment of metastatic pancreatic cancer with a combination of gemcitabine and 5-fluorouracil: a single center phase II study. Tumori 2004;90:192-5. (Pubitemid 38745607)
-
(2004)
Tumori
, vol.90
, Issue.2
, pp. 192-195
-
-
Kanat, O.1
Evrensel, T.2
Kurt, E.3
Demiray, M.4
Gonullu, G.5
Arslan, M.6
Manavoglu, O.7
-
12
-
-
32944478346
-
Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer
-
Kindler HL, Friberg G, Singh DA, et al. Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer. J Clin Oncol 2005;23:8033-40.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8033-8040
-
-
Kindler, H.L.1
Friberg, G.2
Singh, D.A.3
-
13
-
-
0037087787
-
Gemcitabine combined with oxaliplatin in advanced pancreatic adenocarcinoma: Final results of a GERCOR multicenter phase II study
-
Louvet C, Andre T, Lledo G, et al. Gemcitabine combined with oxaliplatin in advanced pancreatic adenocarcinoma: final results of a GERCOR multicenter phase II study. J Clin Oncol 2002;20:1512-8.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1512-1518
-
-
Louvet, C.1
Andre, T.2
Lledo, G.3
-
14
-
-
20644464360
-
Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: Results of a GERCOR and GISCAD phase III trial
-
Louvet C, Labianca R, Hammel P, et al. Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase III trial. J Clin Oncol 2005;23:3509-16.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3509-3516
-
-
Louvet, C.1
Labianca, R.2
Hammel, P.3
-
15
-
-
0033504070
-
Combined chemoradiotherapy for unresectable pancreatic cancer
-
Martin JL, Harvey HA, Lipton A, Martin R. Combined chemoradiotherapy for unresectable pancreatic cancer. Am J Clin Oncol 1999;22:309-14. (Pubitemid 30263330)
-
(1999)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.22
, Issue.3
, pp. 309-314
-
-
Martin, J.L.1
Harvey, H.A.2
Lipton, A.3
Martin, R.4
-
16
-
-
4644308878
-
Clinical study of gemcitabine therapy for recurrent or metastatic pancreatic cancer
-
Moriwaki T, Hyodo I, Nishina T, et al. Clinical study of gemcitabine therapy for recurrent or metastatic pancreatic cancer. Gan To Kagaku Ryoho 2004;31:1373-6.
-
(2004)
Gan to Kagaku Ryoho
, vol.31
, pp. 1373-1376
-
-
Moriwaki, T.1
Hyodo, I.2
Nishina, T.3
-
17
-
-
3242704256
-
Gemcitabine and continuous infusion of 5-fluorouracil in locally advanced and metastatic pancreatic cancer: A phase I-II study
-
Oliani C, Padovani M, Manno P, et al. Gemcitabine and continuous infusion of 5-fluorouracil in locally advanced and metastatic pancreatic cancer: a phase I-II study. Anticancer Res 2004;24:2107-12.
-
(2004)
Anticancer Res
, vol.24
, pp. 2107-2112
-
-
Oliani, C.1
Padovani, M.2
Manno, P.3
-
18
-
-
0035425508
-
Phase II study of gemcitabine and cisplatin in the treatment of patients with advanced pancreatic carcinoma
-
Philip PA, Zalupski MM, Vaitkevicius VK, et al. Phase II study of gemcitabine and cisplatin in the treatment of patients with advanced pancreatic carcinoma. Cancer 2001;92:569-77.
-
(2001)
Cancer
, vol.92
, pp. 569-577
-
-
Philip, P.A.1
Zalupski, M.M.2
Vaitkevicius, V.K.3
-
19
-
-
0842327290
-
Phase II study of external irradiation and weekly paclitaxel for nonmetastatic, unresectable pancreatic cancer: RTOG-98-12
-
Rich T, Harris J, Abrams R, et al. Phase II study of external irradiation and weekly paclitaxel for nonmetastatic, unresectable pancreatic cancer: RTOG-98-12. Am J Clin Oncol 2004;27:51-6.
-
(2004)
Am J Clin Oncol
, vol.27
, pp. 51-56
-
-
Rich, T.1
Harris, J.2
Abrams, R.3
-
20
-
-
4644327989
-
Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
-
Rocha Lima CM, Green MR, Rotche R, et al. Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 2004;22:3776-83.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3776-3783
-
-
Rocha Lima, C.M.1
Green, M.R.2
Rotche, R.3
-
21
-
-
0036498787
-
Irinotecan plus gemcitabine induces both radiographic and CA 19-9 tumor marker responses in patients with previously untreated advanced pancreatic cancer
-
Rocha Lima CM, Savarese D, Bruckner H, et al. Irinotecan plus gemcitabine induces both radiographic and CA 19-9 tumor marker responses in patients with previously untreated advanced pancreatic cancer. J Clin Oncol 2002;20:1182-91.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1182-1191
-
-
Rocha Lima, C.M.1
Savarese, D.2
Bruckner, H.3
-
22
-
-
8944261362
-
A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer
-
Rothenberg ML, Moore MJ, Cripps MC, et al. A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer. Ann Oncol 1996;7:347-53.
-
(1996)
Ann Oncol
, vol.7
, pp. 347-353
-
-
Rothenberg, M.L.1
Moore, M.J.2
Cripps, M.C.3
-
23
-
-
0034122470
-
A phase II study: Docetaxel as first-line chemotherapy for advanced pancreatic adenocarcinoma
-
DOI 10.1016/S0959-8049(00)00072-1, PII S0959804900000721
-
Rougier P, Adenis A, Ducreux M, et al. A phase II study: docetaxel as first-line chemotherapy for advanced pancreatic adenocarcinoma. Eur J Cancer 2000;36:1016-25. (Pubitemid 30316427)
-
(2000)
European Journal of Cancer
, vol.36
, Issue.8
, pp. 1016-1025
-
-
Rougier, P.1
Adenis, A.2
Ducreux, M.3
De Forni, M.4
Bonneterre, J.5
Dembak, M.6
Clouet, P.7
Lebecq, A.8
Baille, P.9
Lefresne-Soulas, F.10
Blanc, C.11
Armand, J.P.12
-
24
-
-
0344305656
-
Phase II study of gemcitabine plus docetaxel in advanced pancreatic cancer: A Hoosier Oncology Group study
-
Schneider BP, Ganjoo KN, Seitz DE, et al. Phase II study of gemcitabine plus docetaxel in advanced pancreatic cancer: a Hoosier Oncology Group study. Oncology 2003;65:218-23.
-
(2003)
Oncology
, vol.65
, pp. 218-223
-
-
Schneider, B.P.1
Ganjoo, K.N.2
Seitz, D.E.3
-
25
-
-
0034938035
-
Combination gemcitabine and docetaxel therapy in advanced adenocarcinoma of the pancreas
-
Sherman WH, Fine RL. Combination gemcitabine and docetaxel therapy in advanced adenocarcinoma of the pancreas. Oncology 2001;60:316-21.
-
(2001)
Oncology
, vol.60
, pp. 316-321
-
-
Sherman, W.H.1
Fine, R.L.2
-
26
-
-
10744225818
-
Front-line treatment of inoperable or metastatic pancreatic cancer with gemcitabine and capecitabine: An intergroup, multicenter, phase II study
-
Stathopoulos GP, Syrigos K, Polyzos A, et al. Front-line treatment of inoperable or metastatic pancreatic cancer with gemcitabine and capecitabine: an intergroup, multicenter, phase II study. Ann Oncol 2004;15:224-9.
-
(2004)
Ann Oncol
, vol.15
, pp. 224-229
-
-
Stathopoulos, G.P.1
Syrigos, K.2
Polyzos, A.3
-
27
-
-
0142121290
-
Randomized phase II comparison of dose-intense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
-
Tempero M, Plunkett W, Ruiz Van Haperen V, et al. Randomized phase II comparison of dose-intense gemcitabine: thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma. J Clin Oncol 2003;21:3402-8.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3402-3408
-
-
Tempero, M.1
Plunkett, W.2
Ruiz Van Haperen, V.3
-
28
-
-
18744378314
-
A pharmacological study of celecoxib and gemcitabine in patients with advanced pancreatic cancer
-
Xiong HQ, Plunkett W, Wolff R, Du M, Lenzi R, Abbruzzese JL. A pharmacological study of celecoxib and gemcitabine in patients with advanced pancreatic cancer. Cancer Chemother Pharmacol 2005;55:559-64.
-
(2005)
Cancer Chemother Pharmacol
, vol.55
, pp. 559-564
-
-
Xiong, H.Q.1
Plunkett, W.2
Wolff, R.3
Du, M.4
Lenzi, R.5
Abbruzzese, J.L.6
-
29
-
-
4344590997
-
Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: A multicenter phase II trial
-
Xiong HQ, Rosenberg A, LoBuglio A, et al. Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: a multicenter phase II trial. J Clin Oncol 2004;22:2610-6.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2610-2616
-
-
Xiong, H.Q.1
Rosenberg, A.2
LoBuglio, A.3
-
31
-
-
10544253077
-
Enhanced sensitivity to 1-β-D-arabinofuranosylcytosine and topoisomerase II inhibitors in tumor cell lines harboring activated ras oncogenes
-
Koo HM, Monks A, Mikheev A, et al. Enhanced sensitivity to 1-β-D-arabinofuranosylcytosine and topoisomerase II inhibitors in tumor cell lines harboring activated ras oncogenes. Cancer Res 1996;56:5211-6.
-
(1996)
Cancer Res
, vol.56
, pp. 5211-5216
-
-
Koo, H.M.1
Monks, A.2
Mikheev, A.3
-
32
-
-
0033518618
-
The ras oncogene-mediated sensitization of human cells to topoisomerase II inhibitor-induced apoptosis
-
Koo HM, Gray-Goodrich M, Kohlhagen G, et al. The ras oncogene-mediated sensitization of human cells to topoisomerase II inhibitor-induced apoptosis. J Natl Cancer Inst 1999;91:236-44. (Pubitemid 29090992)
-
(1999)
Journal of the National Cancer Institute
, vol.91
, Issue.3
, pp. 236-244
-
-
Koo, H.-M.1
Gray-Goodrich, M.2
Kohlhagen, G.3
McWilliams, M.J.4
Jeffers, M.5
Vaigro-Wolff, A.6
Alvord, W.G.7
Monks, A.8
Paull, K.D.9
Pommier, Y.10
Vande Woude, G.F.11
-
33
-
-
2542520155
-
Reanalysis of cancer drugs: Old drugs, new tricks
-
Vande Woude GF, Kelloff GJ, Ruddon RW, et al. Reanalysis of cancer drugs: old drugs, new tricks. Clin Cancer Res 2004;10:3897-907.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3897-3907
-
-
Vande Woude, G.F.1
Kelloff, G.J.2
Ruddon, R.W.3
-
34
-
-
0028214608
-
Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia
-
Neubauer A, Dodge RK, George SL, et al. Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood 1994;83:1603-11.
-
(1994)
Blood
, vol.83
, pp. 1603-1611
-
-
Neubauer, A.1
Dodge, R.K.2
George, S.L.3
-
35
-
-
53749099948
-
Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: A Cancer and Leukemia Group B study
-
Neubauer A, Maharry K, Mrozek K, et al. Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study. J Clin Oncol 2008;26:4603-9.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4603-4609
-
-
Neubauer, A.1
Maharry, K.2
Mrozek, K.3
-
36
-
-
0025285159
-
Ras oncogenes: Their role in neoplasia
-
Barbacid M. ras oncogenes: their role in neoplasia. Eur J Clin Invest 1990;20:225-35.
-
(1990)
Eur J Clin Invest
, vol.20
, pp. 225-235
-
-
Barbacid, M.1
-
37
-
-
68249089660
-
Application of COLD-PCR for improved detection of KRAS mutations in clinical samples
-
Zuo Z, Chen S, Chandra PK, et al. Application of COLD-PCR for improved detection of KRAS mutations in clinical samples. Mod Pathol 2009;22:1023-31.
-
(2009)
Mod Pathol
, vol.22
, pp. 1023-1031
-
-
Zuo, Z.1
Chen, S.2
Chandra, P.K.3
-
38
-
-
0034009704
-
Decrease of CA 19-9 during chemotherapy with gemcitabine predicts survival time in patients with advanced pancreatic cancer
-
Halm U, Schumann T, Schiefke I, Witzigmann H, Mossner J, Keim V. Decrease of CA 19-9 during chemotherapy with gemcitabine predicts survival time in patients with advanced pancreatic cancer. Br J Cancer 2000;82:1013-6.
-
(2000)
Br J Cancer
, vol.82
, pp. 1013-1016
-
-
Halm, U.1
Schumann, T.2
Schiefke, I.3
Witzigmann, H.4
Mossner, J.5
Keim, V.6
-
39
-
-
27144435114
-
CA19-9 as a prognostic factor in inoperable pancreatic cancer: The implication for clinical trials
-
Maisey NR, Norman AR, Hill A, Massey A, Oates J, Cunningham D. CA19-9 as a prognostic factor in inoperable pancreatic cancer: the implication for clinical trials. Br J Cancer 2005;93:740-3.
-
(2005)
Br J Cancer
, vol.93
, pp. 740-743
-
-
Maisey, N.R.1
Norman, A.R.2
Hill, A.3
Massey, A.4
Oates, J.5
Cunningham, D.6
-
40
-
-
0028114788
-
The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia
-
Coghlan DW, Morley AA, Matthews JP, Bishop JF. The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia. Leukemia 1994;8:1682-7.
-
(1994)
Leukemia
, vol.8
, pp. 1682-1687
-
-
Coghlan, D.W.1
Morley, A.A.2
Matthews, J.P.3
Bishop, J.F.4
-
41
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989;49:4682-9.
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
42
-
-
0032764288
-
A dose and schedule finding study of gemcitabine and etoposide in patients with progressive non-small cell lung cancer after platinum containing chemotherapy
-
DOI 10.1016/S0169-5002(99)00033-1, PII S0169500299000331
-
Biesma B, Smit EF, Postmus PE. A dose and schedule finding study of gemcitabine and etoposide in patients with progressive non-small cell lung cancer after platinum containing chemotherapy. Lung Cancer 1999;24:115-21. (Pubitemid 29324714)
-
(1999)
Lung Cancer
, vol.24
, Issue.2
, pp. 115-121
-
-
Biesma, B.1
Smit, E.F.2
Postmus, P.E.3
-
43
-
-
34249933404
-
Erlotinib plus gemcitabine compared to gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG)
-
Moore MJ, Goldstein D, Hamm J, et al. Erlotinib plus gemcitabine compared to gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG). J Clin Oncol 2007;25:1960-6.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
-
44
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S, Zhang X, Parsons DW, et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008;321:1801-6.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
|