메뉴 건너뛰기




Volumn 136, Issue 9, 2010, Pages 1407-1414

Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer

Author keywords

Carcinogenesis; Gastric cancer; Telomere; Telomeric protein

Indexed keywords

BRCA1 PROTEIN; KU ANTIGEN; PROTEIN TIN2; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERIC REPEAT BINDING FACTOR 1; TELOMERIC REPEAT BINDING FACTOR 2; TUMOR MARKER; UNCLASSIFIED DRUG; BRCA1 PROTEIN, HUMAN; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; TELOMERASE; TELOMERE BINDING PROTEIN; TERF2 PROTEIN, HUMAN; TERT PROTEIN, HUMAN; TINF2 PROTEIN, HUMAN;

EID: 77955483828     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-010-0795-x     Document Type: Article
Times cited : (60)

References (37)
  • 1
    • 33745849998 scopus 로고    scopus 로고
    • The structure and function of telomerase reverse transcriptase
    • 10.1146/annurev.biochem.75.103004.142412 10.1146/annurev.biochem.75. 103004.142412 1:CAS:528:DC%2BD28XosVKhs7Y%3D 16756500
    • C Autexier NF Lue 2006 The structure and function of telomerase reverse transcriptase Annu Rev Biochem 75 493 517 10.1146/annurev.biochem.75.103004. 142412 10.1146/annurev.biochem.75.103004.142412 1:CAS:528:DC%2BD28XosVKhs7Y%3D 16756500
    • (2006) Annu Rev Biochem , vol.75 , pp. 493-517
    • Autexier, C.1    Lue, N.F.2
  • 2
    • 33748871127 scopus 로고    scopus 로고
    • Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia
    • 10.1002/ijc.22026 10.1002/ijc.22026 1:CAS:528:DC%2BD28XhtVSks7fL 16786598
    • M Bellon A Datta M Brown, et al. 2006 Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia Int J Cancer 119 9 2090 2097 10.1002/ijc.22026 10.1002/ijc.22026 1:CAS:528:DC%2BD28XhtVSks7fL 16786598
    • (2006) Int J Cancer , vol.119 , Issue.9 , pp. 2090-2097
    • Bellon, M.1    Datta, A.2    Brown, M.3
  • 3
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • 10.1038/350569a0 10.1038/350569a0 1:CAS:528:DyaK3MXisVWnsLg%3D 1708110
    • EH Blackburn 1991 Structure and function of telomeres Nature 350 6319 569 573 10.1038/350569a0 10.1038/350569a0 1:CAS:528:DyaK3MXisVWnsLg%3D 1708110
    • (1991) Nature , vol.350 , Issue.6319 , pp. 569-573
    • Blackburn, E.H.1
  • 4
    • 22944488871 scopus 로고    scopus 로고
    • Telomeres and human disease: Ageing, cancer and beyond
    • 10.1038/nrg1656 10.1038/nrg1656 1:CAS:528:DC%2BD2MXntFeqtbw%3D 16136653
    • MA Blasco 2005 Telomeres and human disease: ageing, cancer and beyond Nat Rev Genet 6 8 611 622 10.1038/nrg1656 10.1038/nrg1656 1:CAS:528: DC%2BD2MXntFeqtbw%3D 16136653
    • (2005) Nat Rev Genet , vol.6 , Issue.8 , pp. 611-622
    • Blasco, M.A.1
  • 5
    • 84984775429 scopus 로고    scopus 로고
    • Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
    • 10.1038/ng1097-231 10.1038/ng1097-231 1:CAS:528:DyaK2sXmsFantb8%3D 9326950
    • D Broccoli A Smogorzewska L Chong, et al. 1997 Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2 Nat Genet 17 2 231 235 10.1038/ng1097-231 10.1038/ng1097-231 1:CAS:528:DyaK2sXmsFantb8%3D 9326950
    • (1997) Nat Genet , vol.17 , Issue.2 , pp. 231-235
    • Broccoli, D.1    Smogorzewska, A.2    Chong, L.3
  • 6
    • 33746644257 scopus 로고    scopus 로고
    • Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
    • 10.1038/ncb1444 10.1038/ncb1444 16845382
    • GB Celli EL Denchi T de Lange, et al. 2006 Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination Nat Cell Biol 8 8 885 890 10.1038/ncb1444 10.1038/ncb1444 16845382
    • (2006) Nat Cell Biol , vol.8 , Issue.8 , pp. 885-890
    • Celli, G.B.1    Denchi, E.L.2    De Lange, T.3
  • 7
    • 0037033062 scopus 로고    scopus 로고
    • Human Ku70/80 associates physically with telomerase through interaction with Htert
    • 10.1074/jbc.M208542200 10.1074/jbc.M208542200 1:CAS:528: DC%2BD38XptFSrsrs%3D 12377759
    • W Chai LP Ford L Lenertz, et al. 2002 Human Ku70/80 associates physically with telomerase through interaction with Htert J Biol Chem 277 49 47242 47247 10.1074/jbc.M208542200 10.1074/jbc.M208542200 1:CAS:528:DC%2BD38XptFSrsrs%3D 12377759
    • (2002) J Biol Chem , vol.277 , Issue.49 , pp. 47242-47247
    • Chai, W.1    Ford, L.P.2    Lenertz, L.3
  • 8
    • 21844468556 scopus 로고    scopus 로고
    • Recent advances in molecular diagnosis and therapy of gastric cancer
    • 10.1159/000083602 10.1159/000083602 15812163
    • J Chen C Rocken P Malfertheiner, et al. 2004 Recent advances in molecular diagnosis and therapy of gastric cancer Dig Dis 22 380 385 10.1159/000083602 10.1159/000083602 15812163
    • (2004) Dig Dis , vol.22 , pp. 380-385
    • Chen, J.1    Rocken, C.2    Malfertheiner, P.3
  • 9
    • 34547900244 scopus 로고    scopus 로고
    • Telomere Maintenance through Spatial Control of Telomeric Proteins
    • 10.1128/MCB.00603-07 10.1128/MCB.00603-07 1:CAS:528:DC%2BD2sXptV2rtr8%3D 17562870
    • LY Chen D Liu Z Songyang, et al. 2007 Telomere Maintenance through Spatial Control of Telomeric Proteins Mol Cell Biol 27 16 5898 5909 10.1128/MCB.00603-07 10.1128/MCB.00603-07 1:CAS:528:DC%2BD2sXptV2rtr8%3D 17562870
    • (2007) Mol Cell Biol , vol.27 , Issue.16 , pp. 5898-5909
    • Chen, L.Y.1    Liu, D.2    Songyang, Z.3
  • 10
    • 0036132673 scopus 로고    scopus 로고
    • Role for the related poly(ADP-ribose) polymerases tankyrase 1 and 2 at human telomeres
    • 10.1128/MCB.22.1.332-342.2002 10.1128/MCB.22.1.332-342.2002 1:CAS:528:DC%2BD3MXptlOiu70%3D 11739745
    • BD Cook JN Dynek W Chang, et al. 2002 Role for the related poly(ADP-ribose) polymerases tankyrase 1 and 2 at human telomeres Mol Cell Biol 22 332 342 10.1128/MCB.22.1.332-342.2002 10.1128/MCB.22.1.332-342.2002 1:CAS:528:DC%2BD3MXptlOiu70%3D 11739745
    • (2002) Mol Cell Biol , vol.22 , pp. 332-342
    • Cook, B.D.1    Dynek, J.N.2    Chang, W.3
  • 11
    • 0029027365 scopus 로고
    • High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCA1-linked families. The Breast Cancer Linkage Consortium
    • 10.1002/gcc.2870130310 10.1002/gcc.2870130310 1:CAS:528: DyaK2MXnt1OmtLs%3D 7669740
    • RS Cornelis SL Neuhausen O Johannson, et al. 1995 High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCA1-linked families. the Breast Cancer Linkage Consortium Genes Chromosom Cancer 13 203 210 10.1002/gcc.2870130310 10.1002/gcc.2870130310 1:CAS:528:DyaK2MXnt1OmtLs%3D 7669740
    • (1995) Genes Chromosom Cancer , vol.13 , pp. 203-210
    • Cornelis, R.S.1    Neuhausen, S.L.2    Johannson, O.3
  • 12
    • 0032872626 scopus 로고    scopus 로고
    • Telomerase activity and telomere lengths: Alterations in renal cell carcinomas
    • 10.1046/j.1523-1755.1999.00688.x 10.1046/j.1523-1755.1999.00688.x 1:CAS:528:DyaK1MXmslGntLo%3D 10504477
    • R Dahse W Fiedler K Junker, et al. 1999 Telomerase activity and telomere lengths: alterations in renal cell carcinomas Kidney Int 56 4 1289 1290 10.1046/j.1523-1755.1999.00688.x 10.1046/j.1523-1755.1999.00688.x 1:CAS:528:DyaK1MXmslGntLo%3D 10504477
    • (1999) Kidney Int , vol.56 , Issue.4 , pp. 1289-1290
    • Dahse, R.1    Fiedler, W.2    Junker, K.3
  • 13
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • 10.1101/gad.1346005 10.1101/gad.1346005 16166375
    • T de Lange 2005 Shelterin: the protein complex that shapes and safeguards human telomeres Genes Dev 19 18 2100 2110 10.1101/gad.1346005 10.1101/gad.1346005 16166375
    • (2005) Genes Dev , vol.19 , Issue.18 , pp. 2100-2110
    • De Lange, T.1
  • 14
    • 31544438868 scopus 로고    scopus 로고
    • Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma
    • 10.1002/cncr.21625 10.1002/cncr.21625 1:CAS:528:DC%2BD28XhsFGiu7s%3D 16388518
    • C Garcia-Aranda C de Juan A Diaz-Lopez, et al. 2006 Correlations of telomere length, telomerase activity, and telomeric-repeat binding factor 1 expression in colorectal carcinoma Cancer 106 3 541 551 10.1002/cncr.21625 10.1002/cncr.21625 1:CAS:528:DC%2BD28XhsFGiu7s%3D 16388518
    • (2006) Cancer , vol.106 , Issue.3 , pp. 541-551
    • Garcia-Aranda, C.1    De Juan, C.2    Diaz-Lopez, A.3
  • 15
    • 0038350026 scopus 로고    scopus 로고
    • Role of telomeres and telomerase in the pathogenesis of human cancer
    • 10.1200/JCO.2003.06.018 10.1200/JCO.2003.06.018 1:CAS:528: DC%2BD2cXptlCktrw%3D 12743159
    • WC Hahn 2003 Role of telomeres and telomerase in the pathogenesis of human cancer J Clin Oncol 21 10 2034 2043 10.1200/JCO.2003.06.018 10.1200/JCO.2003.06.018 1:CAS:528:DC%2BD2cXptlCktrw%3D 12743159
    • (2003) J Clin Oncol , vol.21 , Issue.10 , pp. 2034-2043
    • Hahn, W.C.1
  • 16
    • 0033607160 scopus 로고    scopus 로고
    • Ku is associated with the telomere in mammals
    • 10.1073/pnas.96.22.12454 10.1073/pnas.96.22.12454 1:CAS:528: DyaK1MXnt1yruro%3D 10535943
    • HL Hsu D Gilley EH Blackburn, et al. 1999 Ku is associated with the telomere in mammals Proc Natl Acad Sci USA 96 22 12454 12458 10.1073/pnas.96.22.12454 10.1073/pnas.96.22.12454 1:CAS:528:DyaK1MXnt1yruro%3D 10535943
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.22 , pp. 12454-12458
    • Hsu, H.L.1    Gilley, D.2    Blackburn, E.H.3
  • 17
    • 29844457268 scopus 로고    scopus 로고
    • Expression of telomeric repeat binding factor 1 in non-small cell lung cancer
    • 10.1002/jso.20421 10.1002/jso.20421 1:CAS:528:DC%2BD28XotlOquw%3D%3D 16353195
    • J Hu L Sun C Zhang, et al. 2006 Expression of telomeric repeat binding factor 1 in non-small cell lung cancer J Surg Oncol 93 1 62 67 10.1002/jso.20421 10.1002/jso.20421 1:CAS:528:DC%2BD28XotlOquw%3D%3D 16353195
    • (2006) J Surg Oncol , vol.93 , Issue.1 , pp. 62-67
    • Hu, J.1    Sun, L.2    Zhang, C.3
  • 18
    • 0032727616 scopus 로고    scopus 로고
    • TIN2, a new regulator of telomere length in human cells
    • 10.1038/70508 10.1038/70508 1:CAS:528:DyaK1MXnvFOktb8%3D 10581025
    • SH Kim P Kaminker J Campisi, et al. 1999 TIN2, a new regulator of telomere length in human cells Nat Genet 23 4 405 412 10.1038/70508 10.1038/70508 1:CAS:528:DyaK1MXnvFOktb8%3D 10581025
    • (1999) Nat Genet , vol.23 , Issue.4 , pp. 405-412
    • Kim, S.H.1    Kaminker, P.2    Campisi, J.3
  • 19
    • 0036594926 scopus 로고    scopus 로고
    • Telomere length changes in colorectal cancers and polyps
    • 1:CAS:528:DC%2BD38Xlsl2hurc%3D 12068140
    • HR Kim YJ Kim HJ Kim, et al. 2002 Telomere length changes in colorectal cancers and polyps J Korean Med Sci 17 3 360 365 1:CAS:528:DC%2BD38Xlsl2hurc%3D 12068140
    • (2002) J Korean Med Sci , vol.17 , Issue.3 , pp. 360-365
    • Kim, H.R.1    Kim, Y.J.2    Kim, H.J.3
  • 20
    • 0034716904 scopus 로고    scopus 로고
    • Identification of human Rap1: Implications for telomere evolution
    • 10.1016/S0092-8674(00)80858-2 10.1016/S0092-8674(00)80858-2 1:CAS:528:DC%2BD3cXjvFWntLw%3D 10850490
    • B Li S Oestreich T de Lange, et al. 2000 Identification of human Rap1: implications for telomere evolution Cell 101 471 483 10.1016/S0092-8674(00) 80858-2 10.1016/S0092-8674(00)80858-2 1:CAS:528:DC%2BD3cXjvFWntLw%3D 10850490
    • (2000) Cell , vol.101 , pp. 471-483
    • Li, B.1    Oestreich, S.2    De Lange, T.3
  • 21
    • 0037036349 scopus 로고    scopus 로고
    • A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer
    • 10.1074/jbc.M112231200 10.1074/jbc.M112231200 1:CAS:528: DC%2BD38XkslWnsLk%3D 11916966
    • H Li TH Lee H Avraham, et al. 2002 A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer J Biol Chem 277 23 20965 20973 10.1074/jbc.M112231200 10.1074/jbc.M112231200 1:CAS:528:DC%2BD38XkslWnsLk%3D 11916966
    • (2002) J Biol Chem , vol.277 , Issue.23 , pp. 20965-20973
    • Li, H.1    Lee, T.H.2    Avraham, H.3
  • 22
    • 0035991523 scopus 로고    scopus 로고
    • Correlation between telomerase activity and telomeric-repeat binding factors in gastric cancer
    • 1:CAS:528:DC%2BD38XmvVSrt7w%3D 12148588
    • K Miyachi M Fujita N Tanaka, et al. 2002 Correlation between telomerase activity and telomeric-repeat binding factors in gastric cancer J Exp Clin Cancer Res 21 2 269 275 1:CAS:528:DC%2BD38XmvVSrt7w%3D 12148588
    • (2002) J Exp Clin Cancer Res , vol.21 , Issue.2 , pp. 269-275
    • Miyachi, K.1    Fujita, M.2    Tanaka, N.3
  • 23
    • 0027960790 scopus 로고
    • Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds
    • 1:CAS:528:DyaK2MXisVSqsbw%3D 7954448
    • SL Neuhausen CJ Marshall 1994 Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds Cancer Res 54 6069 6072 1:CAS:528: DyaK2MXisVSqsbw%3D 7954448
    • (1994) Cancer Res , vol.54 , pp. 6069-6072
    • Neuhausen, S.L.1    Marshall, C.J.2
  • 24
    • 11144227269 scopus 로고    scopus 로고
    • Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis
    • 1:CAS:528:DC%2BD2MXnt1ersA%3D%3D 15632001
    • BK Oh YJ Kim C Park, et al. 2005 Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis Am J Pathol 166 1 73 80 1:CAS:528: DC%2BD2MXnt1ersA%3D%3D 15632001
    • (2005) Am J Pathol , vol.166 , Issue.1 , pp. 73-80
    • Oh, B.K.1    Kim, Y.J.2    Park, C.3
  • 25
    • 41349099406 scopus 로고    scopus 로고
    • Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia
    • 10.1182/blood-2007-09-111245 10.1182/blood-2007-09-111245 1:CAS:528:DC%2BD1cXisVeitb8%3D 18077792
    • D Poncet A Belleville C t'kint de Roodenbeke, et al. 2008 Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia Blood 111 4 2388 2391 10.1182/blood-2007-09- 111245 10.1182/blood-2007-09-111245 1:CAS:528:DC%2BD1cXisVeitb8%3D 18077792
    • (2008) Blood , vol.111 , Issue.4 , pp. 2388-2391
    • Poncet, D.1    Belleville, A.2    T'Kint De Roodenbeke, C.3
  • 26
    • 0035218603 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres in human cells
    • 10.1667/0033-7587(2001)155[0194:ALOTIH]2.0.CO;2 10.1667/0033-7587(2001) 155[0194:ALOTIH]2.0.CO;2 1:CAS:528:DC%2BD3MXmtFCjsQ%3D%3D 11121234
    • RR Reddel TM Bryan LM Colgin, et al. 2001 Alternative lengthening of telomeres in human cells Radiat Res 155 1 Pt 2 194 200 10.1667/0033-7587(2001) 155[0194:ALOTIH]2.0.CO;2 10.1667/0033-7587(2001)155[0194:ALOTIH]2.0.CO;2 1:CAS:528:DC%2BD3MXmtFCjsQ%3D%3D 11121234
    • (2001) Radiat Res , vol.155 , Issue.1 PART 2 , pp. 194-200
    • Reddel, R.R.1    Bryan, T.M.2    Colgin, L.M.3
  • 27
    • 0031040086 scopus 로고    scopus 로고
    • TRF1, a mammalian telomeric protein
    • 10.1016/S0168-9525(96)10052-4 10.1016/S0168-9525(96)10052-4 1:CAS:528:DyaK2sXntVGltA%3D%3D 9009844
    • S Smith T de Lange 1997 TRF1, a mammalian telomeric protein Trends Genet 13 1 21 26 10.1016/S0168-9525(96)10052-4 10.1016/S0168-9525(96)10052-4 1:CAS:528:DyaK2sXntVGltA%3D%3D 9009844
    • (1997) Trends Genet , vol.13 , Issue.1 , pp. 21-26
    • Smith, S.1    De Lange, T.2
  • 28
    • 0033961281 scopus 로고    scopus 로고
    • Control of human telomere length by TRF1 and TRF2
    • 10.1128/MCB.20.5.1659-1668.2000 10.1128/MCB.20.5.1659-1668.2000 1:CAS:528:DC%2BD3cXhtF2nt70%3D 10669743
    • A Smogorzewska B van Steensel A Bianchi, et al. 2000 Control of human telomere length by TRF1 and TRF2 Mol Cell Biol 20 5 1659 1668 10.1128/MCB.20.5.1659-1668.2000 10.1128/MCB.20.5.1659-1668.2000 1:CAS:528:DC%2BD3cXhtF2nt70%3D 10669743
    • (2000) Mol Cell Biol , vol.20 , Issue.5 , pp. 1659-1668
    • Smogorzewska, A.1    Van Steensel, B.2    Bianchi, A.3
  • 29
    • 0034623378 scopus 로고    scopus 로고
    • Interaction of human Ku70 with TRF2
    • 10.1016/S0014-5793(00)01958-X 10.1016/S0014-5793(00)01958-X 1:CAS:528:DC%2BD3cXmtlGqsro%3D 10984620
    • K Song D Jung Y Jung, et al. 2000 Interaction of human Ku70 with TRF2 FEBS Lett 481 1 81 85 10.1016/S0014-5793(00)01958-X 10.1016/S0014-5793(00)01958- X 1:CAS:528:DC%2BD3cXmtlGqsro%3D 10984620
    • (2000) FEBS Lett , vol.481 , Issue.1 , pp. 81-85
    • Song, K.1    Jung, D.2    Jung, Y.3
  • 30
    • 0035476710 scopus 로고    scopus 로고
    • T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang
    • 10.1093/emboj/20.19.5532 10.1093/emboj/20.19.5532 1:CAS:528: DC%2BD38XjtVWjuw%3D%3D 11574485
    • RM Stansel T de Lange JD Griffith 2001 T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang EMBO J 20 5532 5540 10.1093/emboj/20.19.5532 10.1093/emboj/20.19.5532 1:CAS:528: DC%2BD38XjtVWjuw%3D%3D 11574485
    • (2001) EMBO J , vol.20 , pp. 5532-5540
    • Stansel, R.M.1    De Lange, T.2    Griffith, J.D.3
  • 31
    • 0031027618 scopus 로고    scopus 로고
    • Control of telomere length by the human telomeric protein TRF1
    • 10.1038/385740a0 10.1038/385740a0
    • T de van Steensel Band 1997 Control of telomere length by the human telomeric protein TRF1 Nature 385 6618 740 743 10.1038/385740a0 10.1038/385740a0
    • (1997) Nature , vol.385 , Issue.6618 , pp. 740-743
    • De Van Steensel Band, T.1
  • 32
    • 0028838096 scopus 로고
    • Changes in mean telomere length in basal cell carcinomas of the skin
    • 10.1002/gcc.2870120108 10.1002/gcc.2870120108 1:STN:280: DyaK2M7psV2hsA%3D%3D 7534110
    • LJ Wainwright PG Middleton JL Rees, et al. 1995 Changes in mean telomere length in basal cell carcinomas of the skin Genes Chromosom Cancer 12 1 45 49 10.1002/gcc.2870120108 10.1002/gcc.2870120108 1:STN:280:DyaK2M7psV2hsA%3D%3D 7534110
    • (1995) Genes Chromosom Cancer , vol.12 , Issue.1 , pp. 45-49
    • Wainwright, L.J.1    Middleton, P.G.2    Rees, J.L.3
  • 33
    • 0242721645 scopus 로고    scopus 로고
    • BRCA1 inhibition of telomerase activity in cultured cells
    • 10.1128/MCB.23.23.8668-8690.2003 10.1128/MCB.23.23.8668-8690.2003 1:CAS:528:DC%2BD3sXptFaisbg%3D 14612409
    • J Xiong S Fan Q Meng, et al. 2003 BRCA1 inhibition of telomerase activity in cultured cells Mol Cell Biol 23 23 8668 8690 10.1128/MCB.23.23.8668-8690. 2003 10.1128/MCB.23.23.8668-8690.2003 1:CAS:528:DC%2BD3sXptFaisbg%3D 14612409
    • (2003) Mol Cell Biol , vol.23 , Issue.23 , pp. 8668-8690
    • Xiong, J.1    Fan, S.2    Meng, Q.3
  • 34
    • 0036870092 scopus 로고    scopus 로고
    • Down-regulation of TRF1, TRF2 and TIN2 genes is important to maintain telomeric DNA for gastric cancers
    • 1:CAS:528:DC%2BD3sXoslyntg%3D%3D 12530079
    • M Yamada N Tsuji M Nakamura, et al. 2002 Down-regulation of TRF1, TRF2 and TIN2 genes is important to maintain telomeric DNA for gastric cancers Anticancer Res 22 6A 3303 3307 1:CAS:528:DC%2BD3sXoslyntg%3D%3D 12530079
    • (2002) Anticancer Res , vol.22 , Issue.6 A , pp. 3303-3307
    • Yamada, M.1    Tsuji, N.2    Nakamura, M.3
  • 35
    • 6944232071 scopus 로고    scopus 로고
    • TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres
    • 10.1074/jbc.M409047200 10.1074/jbc.M409047200 1:CAS:528: DC%2BD2cXptFejt78%3D 15316005
    • JZ Ye JR Donigian M van Overbeek, et al. 2004 TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres J Biol Chem 279 45 47264 47271 10.1074/jbc.M409047200 10.1074/jbc.M409047200 1:CAS:528: DC%2BD2cXptFejt78%3D 15316005
    • (2004) J Biol Chem , vol.279 , Issue.45 , pp. 47264-47271
    • Ye, J.Z.1    Donigian, J.R.2    Van Overbeek, M.3
  • 36
    • 0035798379 scopus 로고    scopus 로고
    • The Pin2/TRF1 interacting protein PinX1 is a potent telomerase inhibitor
    • 10.1016/S0092-8674(01)00538-4 10.1016/S0092-8674(01)00538-4 1:CAS:528:DC%2BD3MXosVKhsbw%3D 11701125
    • XZ Zhou KP Lu 2001 The Pin2/TRF1 interacting protein PinX1 is a potent telomerase inhibitor Cell 107 347 359 10.1016/S0092-8674(01)00538-4 10.1016/S0092-8674(01)00538-4 1:CAS:528:DC%2BD3MXosVKhsbw%3D 11701125
    • (2001) Cell , vol.107 , pp. 347-359
    • Zhou, X.Z.1    Lu, K.P.2
  • 37
    • 0342561644 scopus 로고    scopus 로고
    • Cellcycle-regulated association of Rad50/MRE11/NBS1 with TRF2 and human telomeres
    • 10.1038/77139 10.1038/77139 1:CAS:528:DC%2BD3cXkvFKktb4%3D 10888888
    • XD Zhu B Kuster M Mann, et al. 2000 Cellcycle-regulated association of Rad50/MRE11/NBS1 with TRF2 and human telomeres Nat Genet 25 347 352 10.1038/77139 10.1038/77139 1:CAS:528:DC%2BD3cXkvFKktb4%3D 10888888
    • (2000) Nat Genet , vol.25 , pp. 347-352
    • Zhu, X.D.1    Kuster, B.2    Mann, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.