메뉴 건너뛰기




Volumn 139, Issue 2, 2010, Pages

Evidence of central and peripheral sensitization in a rat model of narcotic bowel-like syndrome

Author keywords

Glia Cells; Morphine; Visceral Pain

Indexed keywords

CD11B ANTIGEN; DOXANTRAZOLE; GENE PRODUCT; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE P38; MORPHINE; NORBINALTORPHIMINE; CHYMASE; CHYMASE 2; DRUG DERIVATIVE; NALTREXONE; NARCOTIC ANTAGONIST; PGP9.5 PROTEIN, RAT; THIOXANTHENE DERIVATIVE; UBIQUITIN THIOLESTERASE; XANTHONE DERIVATIVE;

EID: 77955483320     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.03.046     Document Type: Article
Times cited : (32)

References (53)
  • 1
    • 0035695398 scopus 로고    scopus 로고
    • Incidence, prevalence, and management of opioid bowel dysfunction
    • M. Pappagallo Incidence, prevalence, and management of opioid bowel dysfunction Am J Surg 182 2001 11S 18S
    • (2001) Am J Surg , vol.182
    • Pappagallo, M.1
  • 2
    • 0037249711 scopus 로고    scopus 로고
    • Opioid-induced bowel dysfunction: Pathophysiology and potential new therapies
    • A. Kurz, and D.I. Sessler Opioid-induced bowel dysfunction: pathophysiology and potential new therapies Drugs 63 2003 649 671
    • (2003) Drugs , vol.63 , pp. 649-671
    • Kurz, A.1    Sessler, D.I.2
  • 3
    • 34748903751 scopus 로고    scopus 로고
    • The narcotic bowel syndrome: Clinical features, pathophysiology, and management
    • D.M. Grunkemeier, J.E. Cassara, C.B. Dalton, et al. The narcotic bowel syndrome: clinical features, pathophysiology, and management Clin Gastroenterol Hepatol 5 2007 1126 1139 quiz 1121-1122
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1126-1139
    • Grunkemeier, D.M.1    Cassara, J.E.2    Dalton, C.B.3
  • 4
    • 0022446921 scopus 로고
    • Hyperalgesic response in a patient receiving high concentrations of spinal morphine
    • N.M. Ali Hyperalgesic response in a patient receiving high concentrations of spinal morphine Anesthesiology 65 1986 449
    • (1986) Anesthesiology , vol.65 , pp. 449
    • Ali, N.M.1
  • 5
    • 0025788197 scopus 로고
    • Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine
    • F. De Conno, A. Caraceni, C. Martini, et al. Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine Pain 47 1991 337 339
    • (1991) Pain , vol.47 , pp. 337-339
    • De Conno, F.1    Caraceni, A.2    Martini, C.3
  • 6
    • 66949173732 scopus 로고    scopus 로고
    • Opioid bowel dysfunction and narcotic bowel syndrome: A population-based study
    • R.S. Choung, G.R. Locke 3rd, A.R. Zinsmeister, et al. Opioid bowel dysfunction and narcotic bowel syndrome: a population-based study Am J Gastroenterol 104 2009 1199 1204
    • (2009) Am J Gastroenterol , vol.104 , pp. 1199-1204
    • Choung, R.S.1    Locke III, G.R.2    Zinsmeister, A.R.3
  • 7
    • 0023895008 scopus 로고
    • Clinical experience of long-term treatment with epidural and intrathecal opioids - A nationwide survey
    • S. Arner, N. Rawal, and L.L. Gustafsson Clinical experience of long-term treatment with epidural and intrathecal opioids - a nationwide survey Acta Anaesthesiol Scand 32 1988 253 259
    • (1988) Acta Anaesthesiol Scand , vol.32 , pp. 253-259
    • Arner, S.1    Rawal, N.2    Gustafsson, L.L.3
  • 8
    • 44449119042 scopus 로고    scopus 로고
    • Spinal glial activation contributes to pathological pain states
    • H. Cao, and Y.Q. Zhang Spinal glial activation contributes to pathological pain states Neurosci Biobehav Rev 32 2008 972 983
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 972-983
    • Cao, H.1    Zhang, Y.Q.2
  • 10
    • 26244461682 scopus 로고    scopus 로고
    • Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance?
    • T. King, M.H. Ossipov, T.W. Vanderah, et al. Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance? Neurosignals 14 2005 194 205
    • (2005) Neurosignals , vol.14 , pp. 194-205
    • King, T.1    Ossipov, M.H.2    Vanderah, T.W.3
  • 11
    • 0034666274 scopus 로고    scopus 로고
    • Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance
    • T.W. Vanderah, L.R. Gardell, S.E. Burgess, et al. Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance J Neurosci 20 2000 7074 7079
    • (2000) J Neurosci , vol.20 , pp. 7074-7079
    • Vanderah, T.W.1    Gardell, L.R.2    Burgess, S.E.3
  • 12
    • 0024344214 scopus 로고
    • Mast cells are closely apposed to nerves in the human gastrointestinal mucosa
    • R.H. Stead, M.F. Dixon, N.H. Bramwell, et al. Mast cells are closely apposed to nerves in the human gastrointestinal mucosa Gastroenterology 97 1989 575 585
    • (1989) Gastroenterology , vol.97 , pp. 575-585
    • Stead, R.H.1    Dixon, M.F.2    Bramwell, N.H.3
  • 13
    • 0030938320 scopus 로고    scopus 로고
    • Mediators and pharmacology of visceral sensitivity: From basic to clinical investigations
    • L. Bueno, J. Fioramonti, M. Delvaux, et al. Mediators and pharmacology of visceral sensitivity: from basic to clinical investigations Gastroenterology 112 1997 1714 1743
    • (1997) Gastroenterology , vol.112 , pp. 1714-1743
    • Bueno, L.1    Fioramonti, J.2    Delvaux, M.3
  • 14
    • 0021971485 scopus 로고
    • Comparison of histamine release in human skin mast cells induced by morphine, fentanyl, and oxymorphone
    • J.M. Hermens, J.M. Ebertz, J.M. Hanifin, et al. Comparison of histamine release in human skin mast cells induced by morphine, fentanyl, and oxymorphone Anesthesiology 62 1985 124 129
    • (1985) Anesthesiology , vol.62 , pp. 124-129
    • Hermens, J.M.1    Ebertz, J.M.2    Hanifin, J.M.3
  • 15
    • 0021230369 scopus 로고
    • Induction of human cutaneous mast cell degranulation by opiates and endogenous opioid peptides: Evidence for opiate and nonopiate receptor participation
    • T.B. Casale, S. Bowman, and M. Kaliner Induction of human cutaneous mast cell degranulation by opiates and endogenous opioid peptides: evidence for opiate and nonopiate receptor participation J Allergy Clin Immunol 73 1984 775 781
    • (1984) J Allergy Clin Immunol , vol.73 , pp. 775-781
    • Casale, T.B.1    Bowman, S.2    Kaliner, M.3
  • 16
    • 0021149775 scopus 로고
    • Influence of morphine tolerance and withdrawal on intestinal salt and water transport in the rat in vivo and in vitro
    • G. Warhurst, G.S. Smith, N. Higgs, et al. Influence of morphine tolerance and withdrawal on intestinal salt and water transport in the rat in vivo and in vitro Gastroenterology 87 1984 1035 1041
    • (1984) Gastroenterology , vol.87 , pp. 1035-1041
    • Warhurst, G.1    Smith, G.S.2    Higgs, N.3
  • 17
    • 0023089749 scopus 로고
    • Effects of centrally administered naloxone on gastrointestinal myoelectrical activity in morphine-dependent rats
    • M.P. Primi, and L. Bueno Effects of centrally administered naloxone on gastrointestinal myoelectrical activity in morphine-dependent rats J Pharmacol Exp Ther 240 1987 320 326
    • (1987) J Pharmacol Exp Ther , vol.240 , pp. 320-326
    • Primi, M.P.1    Bueno, L.2
  • 18
    • 11244317215 scopus 로고    scopus 로고
    • The potential of minocycline for neuroprotection in human neurologic disease
    • D. Zemke, and A. Majid The potential of minocycline for neuroprotection in human neurologic disease Clin Neuropharmacol 27 2004 293 298
    • (2004) Clin Neuropharmacol , vol.27 , pp. 293-298
    • Zemke, D.1    Majid, A.2
  • 19
    • 36348974677 scopus 로고    scopus 로고
    • Pharmacological selectivity of CTAP in a warm water tail-withdrawal antinociception assay in rats
    • Berl
    • C.L. Steinmiller, and A.M. Young Pharmacological selectivity of CTAP in a warm water tail-withdrawal antinociception assay in rats Psychopharmacology (Berl) 195 2008 497 507
    • (2008) Psychopharmacology , vol.195 , pp. 497-507
    • Steinmiller, C.L.1    Young, A.M.2
  • 20
    • 0028225153 scopus 로고
    • Interleukin 1 induces a neurally mediated colonic secretion in rats: Involvement of mast cells and prostaglandins
    • V. Theodorou, H. Eutamene, J. Fioramonti, et al. Interleukin 1 induces a neurally mediated colonic secretion in rats: involvement of mast cells and prostaglandins Gastroenterology 106 1994 1493 1500
    • (1994) Gastroenterology , vol.106 , pp. 1493-1500
    • Theodorou, V.1    Eutamene, H.2    Fioramonti, J.3
  • 21
    • 0027287578 scopus 로고
    • A multifunction and programmable computerized barostat
    • T. Hachet, and M. Caussette A multifunction and programmable computerized barostat Gastroenterol Clin Biol 17 1993 347 351
    • (1993) Gastroenterol Clin Biol , vol.17 , pp. 347-351
    • Hachet, T.1    Caussette, M.2
  • 22
    • 0141767048 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing
    • C.I. Svensson, M. Marsala, A. Westerlund, et al. Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing J Neurochem 86 2003 1534 1544
    • (2003) J Neurochem , vol.86 , pp. 1534-1544
    • Svensson, C.I.1    Marsala, M.2    Westerlund, A.3
  • 23
    • 0028018516 scopus 로고
    • Morphine-induced straub tail response: Mediated by central mu2-opioid receptor
    • C. Nath, M.B. Gupta, G.K. Patnaik, et al. Morphine-induced straub tail response: mediated by central mu2-opioid receptor Eur J Pharmacol 263 1994 203 205
    • (1994) Eur J Pharmacol , vol.263 , pp. 203-205
    • Nath, C.1    Gupta, M.B.2    Patnaik, G.K.3
  • 24
    • 0029549990 scopus 로고
    • Opioid antinociception in a rat model of visceral pain: Systemic versus local drug administration
    • R.M. Craft, S.R. Henley, R.C. Haaseth, et al. Opioid antinociception in a rat model of visceral pain: systemic versus local drug administration J Pharmacol Exp Ther 275 1995 1535 1542
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1535-1542
    • Craft, R.M.1    Henley, S.R.2    Haaseth, R.C.3
  • 25
    • 0032455922 scopus 로고    scopus 로고
    • Absorption of morphine from a slow-release emulsion used to induce morphine dependence in rats
    • A. Salem, and W. Hope Absorption of morphine from a slow-release emulsion used to induce morphine dependence in rats J Pharmacol Toxicol Methods 40 1998 159 164
    • (1998) J Pharmacol Toxicol Methods , vol.40 , pp. 159-164
    • Salem, A.1    Hope, W.2
  • 26
    • 0031660108 scopus 로고    scopus 로고
    • Influence of trimebutine on inflammation- and stress-induced hyperalgesia to rectal distension in rats
    • C. Lacheze, A.M. Coelho, J. Fioramonti, et al. Influence of trimebutine on inflammation- and stress-induced hyperalgesia to rectal distension in rats J Pharm Pharmacol 50 1998 921 928
    • (1998) J Pharm Pharmacol , vol.50 , pp. 921-928
    • Lacheze, C.1    Coelho, A.M.2    Fioramonti, J.3
  • 27
    • 0030033921 scopus 로고    scopus 로고
    • The effect of intrathecal opioid-receptor agonists on visceral noxious stimulation in rabbits
    • F.M. Borgbjerg, C. Frigast, J.B. Madsen, et al. The effect of intrathecal opioid-receptor agonists on visceral noxious stimulation in rabbits Gastroenterology 110 1996 139 146
    • (1996) Gastroenterology , vol.110 , pp. 139-146
    • Borgbjerg, F.M.1    Frigast, C.2    Madsen, J.B.3
  • 28
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • T. Tikka, B.L. Fiebich, G. Goldsteins, et al. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia J Neurosci 21 2001 2580 2588
    • (2001) J Neurosci , vol.21 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3
  • 29
    • 0030450402 scopus 로고    scopus 로고
    • A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases
    • A.R. Amin, M.G. Attur, G.D. Thakker, et al. A novel mechanism of action of tetracyclines: effects on nitric oxide synthases Proc Natl Acad Sci U S A 93 1996 14014 14019
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14014-14019
    • Amin, A.R.1    Attur, M.G.2    Thakker, G.D.3
  • 30
    • 62949112107 scopus 로고    scopus 로고
    • Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress
    • S. Bradesi, C.I. Svensson, J. Steinauer, et al. Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress Gastroenterology 136 2009 1339 1348 e1-e2
    • (2009) Gastroenterology , vol.136 , pp. 1339-1348
    • Bradesi, S.1    Svensson, C.I.2    Steinauer, J.3
  • 31
    • 0030859754 scopus 로고    scopus 로고
    • Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat
    • R.W. Colburn, J.A. DeLeo, A.J. Rickman, et al. Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat J Neuroimmunol 79 1997 163 175
    • (1997) J Neuroimmunol , vol.79 , pp. 163-175
    • Colburn, R.W.1    DeLeo, J.A.2    Rickman, A.J.3
  • 32
    • 0031013236 scopus 로고    scopus 로고
    • Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats
    • P.G. Popovich, P. Wei, and B.T. Stokes Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats J Comp Neurol 377 1997 443 464
    • (1997) J Comp Neurol , vol.377 , pp. 443-464
    • Popovich, P.G.1    Wei, P.2    Stokes, B.T.3
  • 33
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • G.W. Kreutzberg Microglia: a sensor for pathological events in the CNS Trends Neurosci 19 1996 312 318
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 34
    • 0031853821 scopus 로고    scopus 로고
    • Cellular mechanisms involved in the modulation of the immune system by drugs of abuse
    • S.L. Chang, B.M. Sharp, and J.J. Madden Cellular mechanisms involved in the modulation of the immune system by drugs of abuse Adv Exp Med Biol 437 1998 1 12
    • (1998) Adv Exp Med Biol , vol.437 , pp. 1-12
    • Chang, S.L.1    Sharp, B.M.2    Madden, J.J.3
  • 35
    • 0032520652 scopus 로고    scopus 로고
    • Autoimmunovascular regulation: Morphine and anandamide and ancondamide stimulated nitric oxide release
    • G.B. Stefano Autoimmunovascular regulation: morphine and anandamide and ancondamide stimulated nitric oxide release J Neuroimmunol 83 1998 70 76
    • (1998) J Neuroimmunol , vol.83 , pp. 70-76
    • Stefano, G.B.1
  • 37
    • 0037112041 scopus 로고    scopus 로고
    • The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats
    • V. Raghavendra, M.D. Rutkowski, and J.A. DeLeo The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats J Neurosci 22 2002 9980 9989
    • (2002) J Neurosci , vol.22 , pp. 9980-9989
    • Raghavendra, V.1    Rutkowski, M.D.2    DeLeo, J.A.3
  • 38
    • 0035111016 scopus 로고    scopus 로고
    • The involvement of glial cells in the development of morphine tolerance
    • P. Song, and Z.Q. Zhao The involvement of glial cells in the development of morphine tolerance Neurosci Res 39 2001 281 286
    • (2001) Neurosci Res , vol.39 , pp. 281-286
    • Song, P.1    Zhao, Z.Q.2
  • 39
    • 0031902771 scopus 로고    scopus 로고
    • Mast cell degranulation induces delayed rectal allodynia in rats: Role of histamine and 5-HT
    • A.M. Coelho, J. Fioramonti, and L. Bueno Mast cell degranulation induces delayed rectal allodynia in rats: role of histamine and 5-HT Dig Dis Sci 43 1998 727 737
    • (1998) Dig Dis Sci , vol.43 , pp. 727-737
    • Coelho, A.M.1    Fioramonti, J.2    Bueno, L.3
  • 40
    • 33846193703 scopus 로고    scopus 로고
    • Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome
    • G. Barbara, B. Wang, V. Stanghellini, et al. Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome Gastroenterology 132 2007 26 37
    • (2007) Gastroenterology , vol.132 , pp. 26-37
    • Barbara, G.1    Wang, B.2    Stanghellini, V.3
  • 41
    • 10744225624 scopus 로고    scopus 로고
    • Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
    • G. Barbara, V. Stanghellini, R. De Giorgio, et al. Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome Gastroenterology 126 2004 693 702
    • (2004) Gastroenterology , vol.126 , pp. 693-702
    • Barbara, G.1    Stanghellini, V.2    De Giorgio, R.3
  • 42
    • 42549171121 scopus 로고    scopus 로고
    • Long-term alterations of colonic nerve-mast cell interactions induced by neonatal maternal deprivation in rats
    • F. Barreau, C. Salvador-Cartier, E. Houdeau, et al. Long-term alterations of colonic nerve-mast cell interactions induced by neonatal maternal deprivation in rats Gut 57 2008 582 590
    • (2008) Gut , vol.57 , pp. 582-590
    • Barreau, F.1    Salvador-Cartier, C.2    Houdeau, E.3
  • 43
    • 34247236607 scopus 로고    scopus 로고
    • Codeine induces human mast cell chemokine and cytokine production: Involvement of G-protein activation
    • C.H. Sheen, R.P. Schleimer, and M. Kulka Codeine induces human mast cell chemokine and cytokine production: involvement of G-protein activation Allergy 62 2007 532 538
    • (2007) Allergy , vol.62 , pp. 532-538
    • Sheen, C.H.1    Schleimer, R.P.2    Kulka, M.3
  • 44
    • 1642452582 scopus 로고    scopus 로고
    • Neurological basis of drug dependence and its effects on the immune system
    • H. Friedman, and T.K. Eisenstein Neurological basis of drug dependence and its effects on the immune system J Neuroimmunol 147 2004 106 108
    • (2004) J Neuroimmunol , vol.147 , pp. 106-108
    • Friedman, H.1    Eisenstein, T.K.2
  • 45
  • 46
    • 0022377810 scopus 로고
    • Different targets for i.v. vs. i.c.v. administered morphine for its effect on colonic motility in dogs
    • J. Fioramonti, M.J. Fargeas, and L. Bueno Different targets for i.v. vs. i.c.v. administered morphine for its effect on colonic motility in dogs Eur J Pharmacol 117 1985 115 120
    • (1985) Eur J Pharmacol , vol.117 , pp. 115-120
    • Fioramonti, J.1    Fargeas, M.J.2    Bueno, L.3
  • 47
    • 0030946385 scopus 로고    scopus 로고
    • Morphine tolerance and dependence in the rat intestine in vivo
    • C.L. Williams, C.C. Bihm, G.C. Rosenfeld, et al. Morphine tolerance and dependence in the rat intestine in vivo J Pharmacol Exp Ther 280 1997 656 663
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 656-663
    • Williams, C.L.1    Bihm, C.C.2    Rosenfeld, G.C.3
  • 48
    • 0024325328 scopus 로고
    • Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model
    • G.S. Ling, D. Paul, R. Simantov, et al. Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model Life Sci 45 1989 1627 1636
    • (1989) Life Sci , vol.45 , pp. 1627-1636
    • Ling, G.S.1    Paul, D.2    Simantov, R.3
  • 49
    • 2442659170 scopus 로고    scopus 로고
    • Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance
    • M. Xu, M. Petraschka, J.P. McLaughlin, et al. Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance J Neurosci 24 2004 4576 4584
    • (2004) J Neurosci , vol.24 , pp. 4576-4584
    • Xu, M.1    Petraschka, M.2    McLaughlin, J.P.3
  • 50
    • 0035282798 scopus 로고    scopus 로고
    • Pronociceptive actions of dynorphin maintain chronic neuropathic pain
    • Z. Wang, L.R. Gardell, M.H. Ossipov, et al. Pronociceptive actions of dynorphin maintain chronic neuropathic pain J Neurosci 21 2001 1779 1786
    • (2001) J Neurosci , vol.21 , pp. 1779-1786
    • Wang, Z.1    Gardell, L.R.2    Ossipov, M.H.3
  • 51
    • 0020051148 scopus 로고
    • Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker
    • P.P. Bradley, D.A. Priebat, R.D. Christensen, et al. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker J Invest Dermatol 78 1982 206 209
    • (1982) J Invest Dermatol , vol.78 , pp. 206-209
    • Bradley, P.P.1    Priebat, D.A.2    Christensen, R.D.3
  • 52
    • 0027080645 scopus 로고
    • Effects of phosphatidylcholine and phosphatidylinositol on acetic-acid-induced colitis in the rat
    • R. Fabio, A. Ar'Rajab, R. Willen, et al. Effects of phosphatidylcholine and phosphatidylinositol on acetic-acid-induced colitis in the rat Digestion 53 1992 35 44
    • (1992) Digestion , vol.53 , pp. 35-44
    • Fabio, R.1    Ar'rajab, A.2    Willen, R.3
  • 53
    • 77049303196 scopus 로고
    • The rate of passage of foodstuffs through the alimentary tract of the goat. I. Studies on adult animals fed on hay and concentrates
    • E.J. Castle The rate of passage of foodstuffs through the alimentary tract of the goat. I. Studies on adult animals fed on hay and concentrates Br J Nutr 10 1956 15 23
    • (1956) Br J Nutr , vol.10 , pp. 15-23
    • Castle, E.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.