Paclitaxel-loaded, folic-acid-targeted and TAT-peptide-conjugated polymeric liposomes: In vitro and in vivo evaluation

Pharmaceutical Research

Volumn 27, Issue 9, 2010, Pages 1914-1926

  Zhao, Peiqi ^a   Wang, Hanjie ^b   Yu, Man ^c   Cao, Shuzhen ^a   Zhang, Fei ^a   Chang, Jin ^b   Niu, Ruifang ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN UNIVERSITY   (China)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

cellular uptake; paclitaxel; polymeric liposomes; target delivery

Indexed keywords

CALCEIN; CREMOPHOR; FOLIC ACID TRANSACTIVATOR PROTEIN POLYMERIC LIPOSOME; LIPOSOME; PACLITAXEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG RELEASE; DRUG TARGETING; DRUG UPTAKE; ENCAPSULATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOSOMAL DELIVERY; MOUSE; NASOPHARYNX CANCER; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SURFACE PROPERTY; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; CHITOSAN; DRUG CARRIERS; DRUG COMPOUNDING; FEMALE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; GENE PRODUCTS, TAT; HUMANS; KB CELLS; LIPOSOMES; MICE; MICE, SCID; MICROSCOPY, ELECTRON, TRANSMISSION; PACLITAXEL; SOLUBILITY; SURFACE PROPERTIES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77955473762     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0196-5     Document Type: Article

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