Differential regulations of blood pressure and perturbed metabolism by total ginsenosides and conventional antihypertensive agents in spontaneously hypertensive rats

Acta Pharmacologica Sinica

Volumn 31, Issue 8, 2010, Pages 930-937

  Aa, Ji Ye ^a   Wang, Guang Ji ^a   Hao, Hai Ping ^a   Huang, Qing ^b   Lu, Yi Hong ^b   Yan, Bei ^c   Zha, Wei Bin ^a   Liu, Lin Sheng ^a   Kang, An ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Jiangsu Institute for Food and Drug Control   (China)

^c BEIJING HOSPITAL   (China)

Author keywords

hypertension; metabolic disorders; metabonomics; spontaneously hypertensive rats; total ginsenosides

Indexed keywords

2 OXOGLUTARIC ACID; 2,3 DIPHOSPHOGLYCERIC ACID; 3 HYDROXYBUTYRIC ACID; ACONITIC ACID; AMLODIPINE; ARACHIDONIC ACID; CAPTOPRIL; CHOLESTEROL; CITRIC ACID; CYSTINE; FATTY ACID; FUMARIC ACID; GINSENOSIDE; GINSENOSIDE RB 1; GINSENOSIDE RB 2; GINSENOSIDE RC; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RG 1; GLUTAMIC ACID; GLYCERIC ACID; GLYCEROPHOSPHATE; HYDROCHLOROTHIAZIDE; LINOLEIC ACID; OLEIC ACID; ORNITHINE; PALMITIC ACID; TERAZOSIN; TRYPTOPHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DISEASE MARKER; DRUG BLOOD LEVEL; DRUG EFFECT; FATTY ACID BLOOD LEVEL; GAS CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HYPERTENSION; MALE; METABOLIC DISORDER; METABOLISM; METABOLOMICS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE ANALYSIS; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; TIME OF FLIGHT MASS SPECTROMETRY; TREATMENT OUTCOME;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; FATTY ACIDS, NONESTERIFIED; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GINSENOSIDES; HYPERTENSION; MALE; RATS; RATS, INBRED SHR;

EID: 77955458466     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.86     Document Type: Article

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