Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold

Journal of Medicinal Chemistry

Volumn 53, Issue 15, 2010, Pages 5576-5586

  Abbenante, Giovanni ^a   Becker, Bernd ^a   Blanc, Sébastien ^b   Clark, Chris ^a   Condie, Glenn ^a   Fraser, Graeme ^b   Grathwohl, Matthias ^a   Halliday, Judy ^a   Henderson, Senka ^a   Lam, Ann ^a   Liu, Ligong ^a   Mann, Maretta ^a   Muldoon, Craig ^a   Pearson, Andrew ^a   Premraj, Rajaratnam ^a   Ramsdale, Tracie ^a   Rossetti, Tony ^a   Schafer, Karl ^a   Le Thanh, Giang ^a   Tometzki, Gerald ^a   Vari, Frank ^a   Verquin, Géraldine ^a   Waanders, Jennifer ^a   West, Michael ^a   Wimmer, Norbert ^a   Yau, Annika ^a   Zuegg, Johannes ^a   Meutermans, Wim ^a   more..

^a Alchemia Pty Ltd   (Australia)

^b Euroscreen   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUND; CARBOHYDRATE DERIVATIVE; MELANIN CONCENTRATING HORMONE RECEPTOR 1; PEPTIDE LIBRARY; PEPTIDOMIMETIC AGENT; PYRANOSE; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 4; SOMATOSTATIN RECEPTOR 5; TRIPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BIODIVERSITY; CHIRALITY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN CONFORMATION; PROTEIN MOTIF;

AMINO ACIDS; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CRICETULUS; DATABASES, FACTUAL; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; MONOSACCHARIDES; OLIGOPEPTIDES; RADIOLIGAND ASSAY; RECEPTORS, SOMATOSTATIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77955448548     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1002777     Document Type: Article

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