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Volumn 34, Issue 8, 2010, Pages

Conversion to sirolimus in renal transplant recipients: A single-center experience

Author keywords

Calcineurin inhibitors; Immunosuppression; Kidney; Nephrotoxicity; Renal; Sirolimus; Transplantation

Indexed keywords

GRAFTS;

EID: 77955443206     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2010.01022.x     Document Type: Article
Times cited : (1)

References (50)
  • 1
    • 0018688143 scopus 로고
    • Cyclosporine A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers
    • Calne RY, Rolles K, White DJ, et al. Cyclosporine A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers. Lancet 1979 2 : 1033 1036.
    • (1979) Lancet , vol.2 , pp. 1033-1036
    • Calne, R.Y.1    Rolles, K.2    White, D.J.3
  • 2
    • 0029857451 scopus 로고    scopus 로고
    • Cyclosporine nephropathy: Pathophysiology and clinical impact
    • Shihab FS. Cyclosporine nephropathy: pathophysiology and clinical impact. Semin Nephrol 1996 16 : 536 547.
    • (1996) Semin Nephrol , vol.16 , pp. 536-547
    • Shihab, F.S.1
  • 4
    • 0032844172 scopus 로고    scopus 로고
    • Chronic allograft nephropathy: An update
    • Paul LC. Chronic allograft nephropathy: an update. Kidney Int 1996 56 : 783 793.
    • (1996) Kidney Int , vol.56 , pp. 783-793
    • Paul, L.C.1
  • 6
    • 0344666767 scopus 로고    scopus 로고
    • The natural history of chronic allograft nephropathy
    • Nankivell BJ, Borrows RJ, Chir B, et al. The natural history of chronic allograft nephropathy. N Engl J Med 2003 349 : 2326 2333.
    • (2003) N Engl J Med , vol.349 , pp. 2326-2333
    • Nankivell, B.J.1    Borrows, R.J.2    Chir, B.3
  • 7
    • 0031813980 scopus 로고    scopus 로고
    • The side effects of cyclosporine-A and tacrolimus
    • Mihatsch MJ, Kyo M, Morozumi K, et al. The side effects of cyclosporine-A and tacrolimus. Clin Nephrol 1998 49 : 356 363.
    • (1998) Clin Nephrol , vol.49 , pp. 356-363
    • Mihatsch, M.J.1    Kyo, M.2    Morozumi, K.3
  • 8
    • 24644523670 scopus 로고    scopus 로고
    • Cancer incidence after immunosuppressive treatment following kidney transplantation
    • Andres A. Cancer incidence after immunosuppressive treatment following kidney transplantation. Crit Rev Oncol Hematol 2005 56 : 71 85.
    • (2005) Crit Rev Oncol Hematol , vol.56 , pp. 71-85
    • Andres, A.1
  • 10
    • 0037184316 scopus 로고    scopus 로고
    • Kidney transplantation without calcineurin inhibitor drugs: A prospective randomized trial of sirolimus versus cyclosporine
    • Flechner SM, Goldfard D, Modlin C, et al. Kidney transplantation without calcineurin inhibitor drugs: a prospective randomized trial of sirolimus versus cyclosporine. Transplantation 2002 74 : 1070 1076.
    • (2002) Transplantation , vol.74 , pp. 1070-1076
    • Flechner, S.M.1    Goldfard, D.2    Modlin, C.3
  • 11
    • 0036174289 scopus 로고    scopus 로고
    • Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
    • Guba M, Von Breitenbuch P, Steinbauer M, et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 2002 8 : 128 135.
    • (2002) Nat Med , vol.8 , pp. 128-135
    • Guba, M.1    Von Breitenbuch, P.2    Steinbauer, M.3
  • 12
    • 0034721757 scopus 로고    scopus 로고
    • Conversion to rapamycin immunosuppression in renal transplant recipients: Report of an initial experience
    • Dominguez J, Mahalati K, Kiberd B, et al. Conversion to rapamycin immunosuppression in renal transplant recipients: report of an initial experience. Transplantation 2000 70 : 1244 1247.
    • (2000) Transplantation , vol.70 , pp. 1244-1247
    • Dominguez, J.1    Mahalati, K.2    Kiberd, B.3
  • 13
    • 0035674916 scopus 로고    scopus 로고
    • Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor induced nephrotoxicity
    • Diekmann F, Waiser J, Fritsche L, et al. Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor induced nephrotoxicity. Transplant Proc 2001 33 : 3234 3235.
    • (2001) Transplant Proc , vol.33 , pp. 3234-3235
    • Diekmann, F.1    Waiser, J.2    Fritsche, L.3
  • 15
    • 27644439969 scopus 로고    scopus 로고
    • Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus
    • Bumbea V, Kamar N, Ribes D, et al. Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus. Nephrol Dial Transplant 2005 20 : 2517 2523.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 2517-2523
    • Bumbea, V.1    Kamar, N.2    Ribes, D.3
  • 16
    • 33645945017 scopus 로고    scopus 로고
    • Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients
    • Stallone G, Infante B, Schena A, et al. Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients. J Am Soc Nephrol 2005 16 : 3755 3762.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3755-3762
    • Stallone, G.1    Infante, B.2    Schena, A.3
  • 17
    • 66449090936 scopus 로고    scopus 로고
    • Management of chronic allograft nephropathy: A systematic review
    • Birnbaum LM, Lipman M, Paraskevas S, et al. Management of chronic allograft nephropathy: a systematic review. Clin J Am Soc Nephrol 2009 4 : 860 865.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 860-865
    • Birnbaum, L.M.1    Lipman, M.2    Paraskevas, S.3
  • 18
    • 0037115133 scopus 로고    scopus 로고
    • Improved renal function in sirolimus-treated renal transplant patients after early cyclosporine elimination
    • Gonwa TA, Hricik DE, Brinker K, Grinyo JM, Schena FP. Improved renal function in sirolimus-treated renal transplant patients after early cyclosporine elimination. Tranplantation 2002 74 : 1560 1567.
    • (2002) Tranplantation , vol.74 , pp. 1560-1567
    • Gonwa, T.A.1    Hricik, D.E.2    Brinker, K.3    Grinyo, J.M.4    Schena, F.P.5
  • 19
    • 0035884710 scopus 로고    scopus 로고
    • Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure
    • Johnson RWG, Kreis H, Oberbauer R, Brattstrom C, Claesson K, Eris J. Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. Transplantation 2001 72 : 777 786.
    • (2001) Transplantation , vol.72 , pp. 777-786
    • Johnson, R.W.G.1    Kreis, H.2    Oberbauer, R.3    Brattstrom, C.4    Claesson, K.5    Eris, J.6
  • 20
    • 0345161813 scopus 로고    scopus 로고
    • Sirolimus (rapamycin)-based therapy in human renal transplantation: Similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group
    • Groth CG, Backman L, Morales JM, et al. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group. Transplantation 1999 67 : 1036 1042.
    • (1999) Transplantation , vol.67 , pp. 1036-1042
    • Groth, C.G.1    Backman, L.2    Morales, J.M.3
  • 21
    • 19244366256 scopus 로고    scopus 로고
    • Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients
    • Morales JM, Wramner L, Kreis H, et al. Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients. Am J Transplant 2002 2 : 436 442.
    • (2002) Am J Transplant , vol.2 , pp. 436-442
    • Morales, J.M.1    Wramner, L.2    Kreis, H.3
  • 22
    • 10744221884 scopus 로고    scopus 로고
    • Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal
    • Kreis H, Oberbauer R, Campistol JM, et al. Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal. J Am Soc Nephrol 2004 15 : 809 817.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 809-817
    • Kreis, H.1    Oberbauer, R.2    Campistol, J.M.3
  • 23
    • 21644457432 scopus 로고    scopus 로고
    • Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation
    • Oberbauer R, Segoloni G, Campistol JM, et al. Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation. Transpl Int 2005 18 : 22 8.
    • (2005) Transpl Int , vol.18 , pp. 22-28
    • Oberbauer, R.1    Segoloni, G.2    Campistol, J.M.3
  • 24
    • 33644694497 scopus 로고    scopus 로고
    • A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation
    • Watson CJ, Firth J, Williams PF, et al. A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation. Am J Transplant 2005 5 : 2496 2503.
    • (2005) Am J Transplant , vol.5 , pp. 2496-2503
    • Watson, C.J.1    Firth, J.2    Williams, P.F.3
  • 25
    • 0034594881 scopus 로고    scopus 로고
    • Improved graft survival after renal transplantation in the United States 1988-1996
    • Hariharan S, Johnson CP, Bresnahan BA, et al. Improved graft survival after renal transplantation in the United States 1988-1996. N Engl J Med 2000 342 : 605 612.
    • (2000) N Engl J Med , vol.342 , pp. 605-612
    • Hariharan, S.1    Johnson, C.P.2    Bresnahan, B.A.3
  • 26
    • 0035011155 scopus 로고    scopus 로고
    • Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation
    • Morales JM, Andres A, Rengel M, Rodicio JL. Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation. Nephrol Dial Transplant 2001 16 : 121 124.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 121-124
    • Morales, J.M.1    Andres, A.2    Rengel, M.3    Rodicio, J.L.4
  • 27
    • 0035165578 scopus 로고    scopus 로고
    • Rapamycin in transplantation: A review of the evidence
    • Saunders RN, Metcalfe MS, Nicholson ML. Rapamycin in transplantation: a review of the evidence. Kidney Int 2001 59 : 3 16.
    • (2001) Kidney Int , vol.59 , pp. 3-16
    • Saunders, R.N.1    Metcalfe, M.S.2    Nicholson, M.L.3
  • 28
    • 0036905019 scopus 로고    scopus 로고
    • Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantation
    • Wyzgal J, Paczek L, Senatorski G, et al. Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantation. Transplant Proc 2002 34 : 3185 3187.
    • (2002) Transplant Proc , vol.34 , pp. 3185-3187
    • Wyzgal, J.1    Paczek, L.2    Senatorski, G.3
  • 29
    • 33750991068 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: A systematic review of the evidence
    • Mulay AV, Cockfield S, Stryker R, Fergusson D, Knoll GA. Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: a systematic review of the evidence. Transplantation 2006 82 : 1153 1162.
    • (2006) Transplantation , vol.82 , pp. 1153-1162
    • Mulay, A.V.1    Cockfield, S.2    Stryker, R.3    Fergusson, D.4    Knoll, G.A.5
  • 30
    • 70349561259 scopus 로고    scopus 로고
    • Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation
    • Egbuna OI, Davis RB, Chudinski R, et al. Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation. Transplantation 2009 88 : 684 692.
    • (2009) Transplantation , vol.88 , pp. 684-692
    • Egbuna, O.I.1    Davis, R.B.2    Chudinski, R.3
  • 31
    • 70350126186 scopus 로고    scopus 로고
    • Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus
    • Servais A, Meas-Yedid V, Toupance O, et al. Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus. Am J Transplant 2009 9 : 2552 2560.
    • (2009) Am J Transplant , vol.9 , pp. 2552-2560
    • Servais, A.1    Meas-Yedid, V.2    Toupance, O.3
  • 32
    • 0037623516 scopus 로고    scopus 로고
    • Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience
    • Morelon E, Kreis H. Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience. Transplant Proc 2003 35 : 52 7.
    • (2003) Transplant Proc , vol.35 , pp. 52-57
    • Morelon, E.1    Kreis, H.2
  • 33
    • 4344686731 scopus 로고    scopus 로고
    • Low-dose sirolimus in combination with mycophenolate mofetil improves kidney graft function late after renal transplantation and suggests pharmacokinetic interaction of both immunosuppressive drugs
    • Renders L, Steinbach R, Valerius T, et al. Low-dose sirolimus in combination with mycophenolate mofetil improves kidney graft function late after renal transplantation and suggests pharmacokinetic interaction of both immunosuppressive drugs. Kidney Blood Press Res 2004 27 : 181 185.
    • (2004) Kidney Blood Press Res , vol.27 , pp. 181-185
    • Renders, L.1    Steinbach, R.2    Valerius, T.3
  • 34
    • 20444498640 scopus 로고    scopus 로고
    • Rapamycin rescue therapy in patients after kidney transplantation: First clinical experience
    • Weber T, Abendroth D, Schelzig H. Rapamycin rescue therapy in patients after kidney transplantation: first clinical experience. Transpl Int 2005 18 : 151 156.
    • (2005) Transpl Int , vol.18 , pp. 151-156
    • Weber, T.1    Abendroth, D.2    Schelzig, H.3
  • 35
    • 15844418962 scopus 로고    scopus 로고
    • Rapamycin in patients with chronic renal allograft dysfunction
    • Wu M-S, Chang C-T, Hung C-C. Rapamycin in patients with chronic renal allograft dysfunction. Clin Transplant 2005 19 : 236 242.
    • (2005) Clin Transplant , vol.19 , pp. 236-242
    • Wu, M.-S.1    Chang, C.-T.2    Hung, C.-C.3
  • 36
    • 59649126728 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial
    • Schena FP, Pascoe MD, Alberu J, et al. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation 2009 87 : 233 242.
    • (2009) Transplantation , vol.87 , pp. 233-242
    • Schena, F.P.1    Pascoe, M.D.2    Alberu, J.3
  • 37
    • 70149114180 scopus 로고    scopus 로고
    • Conversion to sirolimus for chronic allograft nephropathy and calcineurin inhibitor toxicity and the adverse effects of sirolimus after conversion
    • Sayin B, Karakayali H, Colak T, et al. Conversion to sirolimus for chronic allograft nephropathy and calcineurin inhibitor toxicity and the adverse effects of sirolimus after conversion. Transplant Proc 2009 41 : 2789 2793.
    • (2009) Transplant Proc , vol.41 , pp. 2789-2793
    • Sayin, B.1    Karakayali, H.2    Colak, T.3
  • 38
    • 33644872763 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: Benefits and risks
    • Diekmann F, Campistol JM. Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: benefits and risks. Nephrol Dial Transplant 2006 21 : 562 568.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 562-568
    • Diekmann, F.1    Campistol, J.M.2
  • 39
    • 33845423499 scopus 로고    scopus 로고
    • Post-rapamycin proteinuria: Incidence, evolution, and therapeutic handling at a single center
    • Pinheiro HS, Amaro TA, Braga AM, Bastos MG. Post-rapamycin proteinuria: incidence, evolution, and therapeutic handling at a single center. Transplant Proc 2006 38 : 3476 3478.
    • (2006) Transplant Proc , vol.38 , pp. 3476-3478
    • Pinheiro, H.S.1    Amaro, T.A.2    Braga, A.M.3    Bastos, M.G.4
  • 40
    • 33644928466 scopus 로고    scopus 로고
    • Sirolimus-associated heavy proteinuria in a renal transplant recipient: Evidence for a tubular mechanism
    • Straathof-Galema L, Wetzels JF, Dijkman HB, et al. Sirolimus-associated heavy proteinuria in a renal transplant recipient: evidence for a tubular mechanism. Am J Transplant 2006 6 : 429 433.
    • (2006) Am J Transplant , vol.6 , pp. 429-433
    • Straathof-Galema, L.1    Wetzels, J.F.2    Dijkman, H.B.3
  • 41
    • 31544461508 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: Changes in glomerular hemodynamics and proteinuria
    • Saurina A, Campistol JM, Piera C, et al. Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: changes in glomerular hemodynamics and proteinuria. Nephrol Dial Transplant 2006 21 : 488 493.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 488-493
    • Saurina, A.1    Campistol, J.M.2    Piera, C.3
  • 43
    • 2942562298 scopus 로고    scopus 로고
    • Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy
    • Dittrich E, Schmaldienst S, Soleiman A, et al. Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy. Transpl Int 2004 17 : 215 220.
    • (2004) Transpl Int , vol.17 , pp. 215-220
    • Dittrich, E.1    Schmaldienst, S.2    Soleiman, A.3
  • 44
    • 34548685354 scopus 로고    scopus 로고
    • Early sirolimus use with cyclosporine elimination does not induce progressive proteinuria
    • Ruiz JC, Campistol JM, Sanchez-Fructuoso A, et al. Early sirolimus use with cyclosporine elimination does not induce progressive proteinuria. Transplant Proc 2007 39 : 2151 2152.
    • (2007) Transplant Proc , vol.39 , pp. 2151-2152
    • Ruiz, J.C.1    Campistol, J.M.2    Sanchez-Fructuoso, A.3
  • 46
    • 77955450074 scopus 로고    scopus 로고
    • U.S. Renal Data System. USRDS 2008 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Ch. 7. Transplantation. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
    • U.S. Renal Data System. USRDS 2008 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Ch. 7. Transplantation. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2008.
    • (2008)
  • 47
    • 27644436740 scopus 로고    scopus 로고
    • Maintenance immunosuppression with target of rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
    • Kauffman HM, Cherikh WS, Cheng Y, et al. Maintenance immunosuppression with target of rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 2005 80 : 883 889.
    • (2005) Transplantation , vol.80 , pp. 883-889
    • Kauffman, H.M.1    Cherikh, W.S.2    Cheng, Y.3
  • 48
    • 33645458234 scopus 로고    scopus 로고
    • Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation
    • Campistol JM, Eris J, Oberbauer R, et al. Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation. J Am Soc Nephrol 2006 17 : 581 589.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 581-589
    • Campistol, J.M.1    Eris, J.2    Oberbauer, R.3
  • 50
    • 0037623464 scopus 로고    scopus 로고
    • Tubular function in patients with hypokalemia induced by sirolimus after renal transplantation
    • Morales JM, Andres A, Dominguez-Gil B, et al. Tubular function in patients with hypokalemia induced by sirolimus after renal transplantation. Transplant Proc 2003 35 : 154 156.
    • (2003) Transplant Proc , vol.35 , pp. 154-156
    • Morales, J.M.1    Andres, A.2    Dominguez-Gil, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.