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Volumn 82, Issue 9, 2006, Pages 1153-1162

Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: A systematic review of the evidence

Author keywords

Calcineurin inhibitor; Chronic allograft nephropathy; Kidney transplantation; Meta analysis; Sirolimus; Systematic review

Indexed keywords

CALCINEURIN INHIBITOR; CHOLESTEROL; EVEROLIMUS; RAPAMYCIN; TRIACYLGLYCEROL;

EID: 33750991068     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000237101.58974.43     Document Type: Review
Times cited : (93)

References (75)
  • 1
    • 0001144473 scopus 로고    scopus 로고
    • US Renal Data System: Excerpts from the USRDS 2003 Annual Data Report: Atlas of End-Stage Renal Disease in the United States
    • US Renal data system
    • US Renal data system. US Renal Data System: Excerpts from the USRDS 2003 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Am J Kidney Dis 2003; 42: s1-s230.
    • (2003) Am J Kidney Dis , vol.42
  • 2
    • 0033518231 scopus 로고    scopus 로고
    • Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant
    • Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999; 341: 1725.
    • (1999) N Engl J Med , vol.341 , pp. 1725
    • Wolfe, R.A.1    Ashby, V.B.2    Milford, E.L.3
  • 3
    • 0029833753 scopus 로고    scopus 로고
    • A study of the quality of life and cost-utility of renal transplantation
    • Laupacis A, Keown P, Pus N, et al. A study of the quality of life and cost-utility of renal transplantation. Kidney Int 1996; 50: 235.
    • (1996) Kidney Int , vol.50 , pp. 235
    • Laupacis, A.1    Keown, P.2    Pus, N.3
  • 4
    • 0034005754 scopus 로고    scopus 로고
    • Long-term survival in renal transplant recipients with graft function
    • Ojo AO, Hanson JA, Wolfe RA, et al. Long-term survival in renal transplant recipients with graft function. Kidney Int 2000; 57: 307.
    • (2000) Kidney Int , vol.57 , pp. 307
    • Ojo, A.O.1    Hanson, J.A.2    Wolfe, R.A.3
  • 5
    • 33748286715 scopus 로고    scopus 로고
    • Longitudinal analysis of chronic allograft nephropathy: Clinicopathologic correlations
    • Chapman JR. Longitudinal analysis of chronic allograft nephropathy: clinicopathologic correlations. Kidney Int 2005; S108-S112.
    • (2005) Kidney Int
    • Chapman, J.R.1
  • 6
    • 0036870918 scopus 로고    scopus 로고
    • Death after graft loss: An important late study endpoint in kidney transplantation
    • Kaplan B, Meier-Kriesche HU. Death after graft loss: an important late study endpoint in kidney transplantation. Am J Transplant 2002; 2: 970.
    • (2002) Am J Transplant , vol.2 , pp. 970
    • Kaplan, B.1    Meier-Kriesche, H.U.2
  • 7
    • 21344444380 scopus 로고    scopus 로고
    • Patient survival following renal transplant failure in Canada
    • Knoll G, Muirhead N, Trpeski L, et al. Patient survival following renal transplant failure in Canada. Am J Transplant 2005; 5: 1719.
    • (2005) Am J Transplant , vol.5 , pp. 1719
    • Knoll, G.1    Muirhead, N.2    Trpeski, L.3
  • 9
    • 0032946290 scopus 로고    scopus 로고
    • Rethinking Chronic Allograft Nephropathy: The Concept of Accelerated Senescence
    • Halloran PF, Melk A, Barth C. Rethinking Chronic Allograft Nephropathy: The Concept of Accelerated Senescence. J Am Soc Nephrol 1999; 10: 167.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 167
    • Halloran, P.F.1    Melk, A.2    Barth, C.3
  • 10
    • 33748301936 scopus 로고    scopus 로고
    • Immunosuppressive treatment and progression of histologic lesions in kidney allografts
    • Morales JM. Immunosuppressive treatment and progression of histologic lesions in kidney allografts. Kidney Int Suppl 2005; S124-S130.
    • (2005) Kidney Int Suppl
    • Morales, J.M.1
  • 11
    • 0344666767 scopus 로고    scopus 로고
    • The natural history of chronic allograft nephropathy
    • Nankivell BJ, Borrows RJ, Fung CL, et al. The natural history of chronic allograft nephropathy. N Engl J Med 2003; 349: 2326.
    • (2003) N Engl J Med , vol.349 , pp. 2326
    • Nankivell, B.J.1    Borrows, R.J.2    Fung, C.L.3
  • 12
    • 0032844172 scopus 로고    scopus 로고
    • Chronic allograft nephropathy: An update
    • Paul LC. Chronic allograft nephropathy: An update. Kidney Int 1999; 56: 783.
    • (1999) Kidney Int , vol.56 , pp. 783
    • Paul, L.C.1
  • 13
    • 0141468244 scopus 로고    scopus 로고
    • Kidney Disease as a Risk Factor for Development of Cardiovascular Disease: A Statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention
    • Sarnak MJ, Levey AS, Schoolwerth AC, et al. Kidney Disease as a Risk Factor for Development of Cardiovascular Disease: A Statement From the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 2003; 108: 2154.
    • (2003) Circulation , vol.108 , pp. 2154
    • Sarnak, M.J.1    Levey, A.S.2    Schoolwerth, A.C.3
  • 14
    • 0033979599 scopus 로고    scopus 로고
    • Nephrotoxicity of immunosuppressive drugs: Long-term consequences and challenges for the future
    • de Mattos A, Olyaei A, Bennett W. Nephrotoxicity of immunosuppressive drugs: Long-term consequences and challenges for the future. Am J Kidney Dis 2000; 35: 333.
    • (2000) Am J Kidney Dis , vol.35 , pp. 333
    • De Mattos, A.1    Olyaei, A.2    Bennett, W.3
  • 15
    • 0037979128 scopus 로고    scopus 로고
    • Pathogenesis of chronic allograft rejection
    • Joosten S, van Kooten C, Paul L. Pathogenesis of chronic allograft rejection. Transplant Int 2003; 16: 137.
    • (2003) Transplant Int , vol.16 , pp. 137
    • Joosten, S.1    Van Kooten, C.2    Paul, L.3
  • 16
    • 4644277373 scopus 로고    scopus 로고
    • Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function
    • Weir MR, Blahut S, Drachenburg C, et al. Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. Am J Nephrol 2004; 24(4): 379.
    • (2004) Am J Nephrol , vol.24 , Issue.4 , pp. 379
    • Weir, M.R.1    Blahut, S.2    Drachenburg, C.3
  • 17
    • 1942502227 scopus 로고    scopus 로고
    • Withdrawal of Cyclosporine or Tacrolimus after Addition of Mycophenolate Mofetil in Patients with Chronic Allograft Nephropathy
    • Suwelack B, Gerhardt U, Hohage H. Withdrawal of Cyclosporine or Tacrolimus After Addition of Mycophenolate Mofetil in Patients With Chronic Allograft Nephropathy. Am J Transplant 2004; 4: 655.
    • (2004) Am J Transplant , vol.4 , pp. 655
    • Suwelack, B.1    Gerhardt, U.2    Hohage, H.3
  • 18
    • 0035011155 scopus 로고    scopus 로고
    • Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation
    • Morales JM, Andres A, Rengel M, Rodicio JL. Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation. Nephrol Dial Transplant 2001; 16: 121.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 121
    • Morales, J.M.1    Andres, A.2    Rengel, M.3    Rodicio, J.L.4
  • 19
  • 20
    • 0034721757 scopus 로고    scopus 로고
    • Conversion to rapamycin immunosuppression in renal transplant recipients: Report of an initial experience
    • Dominguez J, Mahalati K, Kiberd B, et al. Conversion to rapamycin immunosuppression in renal transplant recipients: report of an initial experience. Transplantation 2000; 70: 1244.
    • (2000) Transplantation , vol.70 , pp. 1244
    • Dominguez, J.1    Mahalati, K.2    Kiberd, B.3
  • 21
    • 0036905019 scopus 로고    scopus 로고
    • Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantation
    • Wyzgal J, Paczek L, Senatorski G, et al. Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantation. Transplant Proc 2002; 34: 3185.
    • (2002) Transplant Proc , vol.34 , pp. 3185
    • Wyzgal, J.1    Paczek, L.2    Senatorski, G.3
  • 22
    • 33645945017 scopus 로고    scopus 로고
    • Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients
    • Stallone G, Infante B, Schena A, et al. Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients. J Am Soc Nephrol 2005; 16: 3755.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3755
    • Stallone, G.1    Infante, B.2    Schena, A.3
  • 24
    • 33751020778 scopus 로고    scopus 로고
    • A Randomized, open label, comparative evaluation of the safety and efficacy of conversion from calcineurin inhibitors to sirolimus versus continued use of calcineurin inhibitors in renal allograft recipients
    • [Abstract]
    • Schena FP, Wali RK, Pascoe MD, et al. A Randomized, open label, comparative evaluation of the safety and efficacy of conversion from calcineurin inhibitors to sirolimus versus continued use of calcineurin inhibitors in renal allograft recipients [Abstract]. Transpl Int 2005; 18 (Suppl 1): 155.
    • (2005) Transpl Int , vol.18 , Issue.SUPPL. 1 , pp. 155
    • Schena, F.P.1    Wali, R.K.2    Pascoe, M.D.3
  • 25
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
    • Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17(1): 1.
    • (1996) Control Clin Trials , vol.17 , Issue.1 , pp. 1
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 26
    • 33644694497 scopus 로고    scopus 로고
    • A Randomized Controlled Trial of Late Conversion from CNI-Based to Sirolimus-Based Immunosuppression Following Renal Transplantation
    • Watson CJ, Firth J, Williams PF et al. A Randomized Controlled Trial of Late Conversion from CNI-Based to Sirolimus-Based Immunosuppression Following Renal Transplantation. Am J Transplant 2005; 5: 2496.
    • (2005) Am J Transplant , vol.5 , pp. 2496
    • Watson, C.J.1    Firth, J.2    Williams, P.F.3
  • 27
    • 84948773232 scopus 로고    scopus 로고
    • Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis
    • Egger MD-SGADG, ed. BMJ Publishing Group
    • Deeks JJ, Altman DG, Bradburn MJ. Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In: Egger MD-SGADG, ed. Systematic Reviews in Health Care. BMJ Publishing Group, 2001; 285-312.
    • (2001) Systematic Reviews in Health Care , pp. 285-312
    • Deeks, J.J.1    Altman, D.G.2    Bradburn, M.J.3
  • 28
    • 0032580320 scopus 로고    scopus 로고
    • Two-sided confidence intervals for the single proportion: Comparison of seven methods
    • Newcombe RG. Two-sided confidence intervals for the single proportion: comparison of seven methods. Stat Med 1998; 17(8): 857.
    • (1998) Stat Med , vol.17 , Issue.8 , pp. 857
    • Newcombe, R.G.1
  • 29
    • 0033559185 scopus 로고    scopus 로고
    • Methods for combining rates from several studies
    • Zhou XH, Brizendine EJ, Pritz MB. Methods for combining rates from several studies. Stat Med 1999; 18(5): 557.
    • (1999) Stat Med , vol.18 , Issue.5 , pp. 557
    • Zhou, X.H.1    Brizendine, E.J.2    Pritz, M.B.3
  • 30
    • 27644521658 scopus 로고    scopus 로고
    • Rapamycin substitution for calcineurin inhibitors in renal transplant recipients with chronic allograft nephropathy
    • [Abstract]
    • Amm J, Ramamurthy G, Degala A, et al. Rapamycin substitution for calcineurin inhibitors in renal transplant recipients with chronic allograft nephropathy [Abstract]. Am J Transplant 2003; 3 (S5): 211.
    • (2003) Am J Transplant , vol.3 , Issue.S5 , pp. 211
    • Amm, J.1    Ramamurthy, G.2    Degala, A.3
  • 31
    • 4344686731 scopus 로고    scopus 로고
    • Low-dose sirolimus in combination with mycophenolate mofetil improves kidney graft function late after renal transplantation and suggests pharmacokinetic interaction of both immunosuppressive drugs
    • Renders L, Steinbach R, Valerius T, et al. Low-dose sirolimus in combination with mycophenolate mofetil improves kidney graft function late after renal transplantation and suggests pharmacokinetic interaction of both immunosuppressive drugs. Kidney Blood Press Res 2004; 27: 181.
    • (2004) Kidney Blood Press Res , vol.27 , pp. 181
    • Renders, L.1    Steinbach, R.2    Valerius, T.3
  • 32
    • 33751016596 scopus 로고    scopus 로고
    • Six month interim analysis of a phase III prospective, randomised study to compare conversion from calcineurin inhibitors to rapamycin in established renal allograft recipients with mild to moderate renal insufficiency
    • [Abstract]
    • Baboolal K. Six month interim analysis of a phase III prospective, randomised study to compare conversion from calcineurin inhibitors to rapamycin in established renal allograft recipients with mild to moderate renal insufficiency [Abstract]. Am J Transplant 2004; 4 (S8): 220.
    • (2004) Am J Transplant , vol.4 , Issue.S8 , pp. 220
    • Baboolal, K.1
  • 33
    • 0037783795 scopus 로고    scopus 로고
    • Rapid conversion to sirolimus for chronic progressive deterioration of the renal function in kidney allograft recipients
    • Citterlo F, Scata MC, Violi P, et al. Rapid conversion to sirolimus for chronic progressive deterioration of the renal function in kidney allograft recipients. Transplant Proc 2003; 35: 1292.
    • (2003) Transplant Proc , vol.35 , pp. 1292
    • Citterlo, F.1    Scata, M.C.2    Violi, P.3
  • 34
    • 28444499887 scopus 로고    scopus 로고
    • A single center experience with sirolimus conversion therapy in renal allograft recipients
    • [Abstract]
    • Crowley KL, Hardinger KL, Koch M, et al. A single center experience with sirolimus conversion therapy in renal allograft recipients [Abstract]. Am J Transplant 2003; 3 (S5): 354.
    • (2003) Am J Transplant , vol.3 , Issue.S5 , pp. 354
    • Crowley, K.L.1    Hardinger, K.L.2    Koch, M.3
  • 35
    • 0035674916 scopus 로고    scopus 로고
    • Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor-induced nephrotoxicity
    • Diekmann F, Waiser J, Fritsche L, et al. Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor-induced nephrotoxicity. Transplant Proc 2001; 33: 3234.
    • (2001) Transplant Proc , vol.33 , pp. 3234
    • Diekmann, F.1    Waiser, J.2    Fritsche, L.3
  • 36
    • 7244245756 scopus 로고    scopus 로고
    • Predictors of success in conversion from calcineurin inhibitor to sirolimus in chronic allograft dysfunction
    • Diekmann F, Budde K, Oppenheimer F, et al. Predictors of success in conversion from calcineurin inhibitor to sirolimus in chronic allograft dysfunction. Am J Transplant 2004; 4: 1869.
    • (2004) Am J Transplant , vol.4 , pp. 1869
    • Diekmann, F.1    Budde, K.2    Oppenheimer, F.3
  • 37
    • 0038298952 scopus 로고    scopus 로고
    • Conversion to sirolimus in solid organ transplantation: A single-center experience
    • Egidi MF, Cowan PA, Naseer A, Gaber AO. Conversion to sirolimus in solid organ transplantation: a single-center experience. Transplant Proc 2003; 35: 131S.
    • (2003) Transplant Proc , vol.35
    • Egidi, M.F.1    Cowan, P.A.2    Naseer, A.3    Gaber, A.O.4
  • 38
    • 13644268256 scopus 로고    scopus 로고
    • Determinants of long term preservation of renal function after conversion to sirolimus in patients with chronic allograft nephropathy
    • [Abstract]
    • Guasch A, Near M, Selvaraj S. Determinants of long term preservation of renal function after conversion to sirolimus in patients with chronic allograft nephropathy [Abstract]. Am J Transplant 2004; 4(S8): 266.
    • (2004) Am J Transplant , vol.4 , Issue.S8 , pp. 266
    • Guasch, A.1    Near, M.2    Selvaraj, S.3
  • 39
    • 33750968731 scopus 로고    scopus 로고
    • Nephrotic range proteinuria and other severe adverse events after conversion to sirolimus in renal transplantation: Is high exposure to sirolimus responsible?
    • [Abstract]
    • Hadaya K, Wissing M, Broeders N, Abramowicz D. Nephrotic range proteinuria and other severe adverse events after conversion to sirolimus in renal transplantation: Is high exposure to sirolimus responsible? [Abstract]. Am J Transplant 2004; 4(S8): 433.
    • (2004) Am J Transplant , vol.4 , Issue.S8 , pp. 433
    • Hadaya, K.1    Wissing, M.2    Broeders, N.3    Abramowicz, D.4
  • 40
    • 30144433497 scopus 로고    scopus 로고
    • Proteinuria following switch from calcineurin inhibitors to sirolimus: A retrospective study
    • [Abstract]
    • Letavernier E, Peraldi M, Kreis H, Legendre C. Proteinuria following switch from calcineurin inhibitors to sirolimus: A retrospective study [Abstract]. Am J Transplant 2004; 4(S8): 161.
    • (2004) Am J Transplant , vol.4 , Issue.S8 , pp. 161
    • Letavernier, E.1    Peraldi, M.2    Kreis, H.3    Legendre, C.4
  • 41
    • 33750967590 scopus 로고    scopus 로고
    • Late conversion to sirolimus in a kidney transplant population: Is it worth?
    • [Abstract]
    • Lord H, Boucher A, Morin M, Dandavino R. Late conversion to sirolimus in a kidney transplant population: Is it worth? [Abstract]. Am J Transplant 2004; 4 (S8): 221.
    • (2004) Am J Transplant , vol.4 , Issue.S8 , pp. 221
    • Lord, H.1    Boucher, A.2    Morin, M.3    Dandavino, R.4
  • 42
    • 28444436796 scopus 로고    scopus 로고
    • An open non comparative pilot study of renal function after conversion from cyclosporin (CsA) to sirolimus (SRL) in stable renal allograft recipients with mild to moderate renal insufficiency
    • [Abstract]
    • Paczek L, Dedochova J, Matl I, Pohanka E. An open non comparative pilot study of renal function after conversion from cyclosporin (CsA) to sirolimus (SRL) in stable renal allograft recipients with mild to moderate renal insufficiency [Abstract]. Am J Transplant 2003; 3 (S5): 217.
    • (2003) Am J Transplant , vol.3 , Issue.S5 , pp. 217
    • Paczek, L.1    Dedochova, J.2    Matl, I.3    Pohanka, E.4
  • 43
    • 13644265974 scopus 로고    scopus 로고
    • An open-label pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency
    • Peddi VR, Jensik S, Pescovitz M, et al. An open-label pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency. Clin Transplant 2005; 19: 130.
    • (2005) Clin Transplant , vol.19 , pp. 130
    • Peddi, V.R.1    Jensik, S.2    Pescovitz, M.3
  • 44
    • 33751007490 scopus 로고    scopus 로고
    • Chronic allograft damage index (CADI)2 scoring at conversion from calcineurin inhibitors (CI) to sirolimus predicts renal outcome in kidney transplant recipients
    • [Abstract]
    • Sankaranarayanan N, Balarezo F, Alleman K, et al. Chronic allograft damage index (CADI)2 scoring at conversion from calcineurin inhibitors (CI) to sirolimus predicts renal outcome in kidney transplant recipients[Abstract]. Am J Transplant 2004; 4 (S8): 296.
    • (2004) Am J Transplant , vol.4 , Issue.S8 , pp. 296
    • Sankaranarayanan, N.1    Balarezo, F.2    Alleman, K.3
  • 45
    • 33750977213 scopus 로고    scopus 로고
    • Late introduction of sirolimus introduces anemia of inflammatory state in renal transplant recipients
    • [Abstract]
    • Thaunat O, Lechaton, Mamzer M, et al. Late introduction of sirolimus introduces anemia of inflammatory state in renal transplant recipients. [Abstract]. Am J Transplant 2005; 5 (S11): 554.
    • (2005) Am J Transplant , vol.5 , Issue.S11 , pp. 554
    • Thaunat, O.1    Lechaton2    Mamzer, M.3
  • 46
    • 0345118182 scopus 로고    scopus 로고
    • Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil
    • van Gelder T, ter Meulen CG, Hene R, et al. Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil. Transplantation 2003; 75: 788.
    • (2003) Transplantation , vol.75 , pp. 788
    • Van Gelder, T.1    Ter Meulen, C.G.2    Hene, R.3
  • 47
    • 28444491603 scopus 로고    scopus 로고
    • Can we change the progressive decay in graft function after the onset of chronic allograft nephropathy (CAN) in the recipients of kidney allografts? (preliminary results of the ongoing study)
    • [Abstract]
    • Wali RK, Richards A, Cunningham R, et al. Can we change the progressive decay in graft function after the onset of chronic allograft nephropathy (CAN) in the recipients of kidney allografts? (preliminary results of the ongoing study) [Abstract]. Am J Transplant 2003; 3 (S5): 336.
    • (2003) Am J Transplant , vol.3 , Issue.S5 , pp. 336
    • Wali, R.K.1    Richards, A.2    Cunningham, R.3
  • 48
    • 4544353838 scopus 로고    scopus 로고
    • Conversion to sirolimus-based maintenance immunosuppression using daclizumab bridge therapy in renal transplant recipients
    • Sundberg AK, Rohr MS, Hartmann EL, et al. Conversion to sirolimus-based maintenance immunosuppression using daclizumab bridge therapy in renal transplant recipients. Clin Transplant 2004; 18: 61.
    • (2004) Clin Transplant , vol.18 , pp. 61
    • Sundberg, A.K.1    Rohr, M.S.2    Hartmann, E.L.3
  • 49
    • 33750971395 scopus 로고    scopus 로고
    • Conversion to and from sirolimus in renal and hepatic transplant recipients treated with calcineurin inhibitors:Effect on renal function
    • [Abstract]
    • Moneim HA, Fletchner SM, George P, et al. Conversion to and from sirolimus in renal and hepatic transplant recipients treated with calcineurin inhibitors:Effect on renal function.[Abstract]. Am J Transplant 2005; 5(S11): 376.
    • (2005) Am J Transplant , vol.5 , Issue.S11 , pp. 376
    • Moneim, H.A.1    Fletchner, S.M.2    George, P.3
  • 50
    • 33750969312 scopus 로고    scopus 로고
    • Sirolimus associated proteinuria. Study in kidney (KTx) and heart (HTx) recipients after calcineurin inhibitor (CNI) withdrawal and in KTX with sirolimus de novo immunosuppression
    • [Abstract]
    • Lacha J, Bartosova K, Matl I, et al. Sirolimus associated proteinuria. Study in kidney (KTx) and heart (HTx) recipients after calcineurin inhibitor (CNI) withdrawal and in KTX with sirolimus de novo immunosuppression [Abstract]. Am J Transplant 2005; 5: 414.
    • (2005) Am J Transplant , vol.5 , pp. 414
    • Lacha, J.1    Bartosova, K.2    Matl, I.3
  • 51
    • 27644485782 scopus 로고    scopus 로고
    • Switch of immunosuppression from calcineurin inhibitors (CNI) to sirolimus (SRL) in pediatric renal transplant recipients with CNI toxicity
    • [Abstract]
    • Hoecker B, Feneberg R, Koepf S, et al. Switch of immunosuppression from calcineurin inhibitors (CNI) to sirolimus (SRL) in pediatric renal transplant recipients with CNI toxicity [Abstract]. Am J Transplant 2005; 5(S11): 497.
    • (2005) Am J Transplant , vol.5 , Issue.S11 , pp. 497
    • Hoecker, B.1    Feneberg, R.2    Koepf, S.3
  • 52
    • 33751004072 scopus 로고    scopus 로고
    • Evolution of proteinuria after conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) in renal transplant patients. A multicenter study
    • [Abstract]
    • Ruiz JC, Diekmann F, Campistol JM, et al. Evolution of proteinuria after conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) in renal transplant patients. A multicenter study [Abstract]. Am J Transplant 2005; 5(S11): 519.
    • (2005) Am J Transplant , vol.5 , Issue.S11 , pp. 519
    • Ruiz, J.C.1    Diekmann, F.2    Campistol, J.M.3
  • 53
    • 15844418962 scopus 로고    scopus 로고
    • Rapamycin in patients with chronic renal allograft dysfunction
    • Wu M-S, Chang C-T, Hung C-C. Rapamycin in patients with chronic renal allograft dysfunction. Clin Transplant 2005; 19: 236.
    • (2005) Clin Transplant , vol.19 , pp. 236
    • Wu, M.-S.1    Chang, C.-T.2    Hung, C.-C.3
  • 54
    • 27644439969 scopus 로고    scopus 로고
    • Long term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus
    • Bumbea V, Kamar N, Ribes D, et al. Long term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus. Nephrol Dial Transplant 2005; 20: 2517.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 2517
    • Bumbea, V.1    Kamar, N.2    Ribes, D.3
  • 55
    • 0242552407 scopus 로고    scopus 로고
    • Low-dose sirolimus in combination with mycophenolate in calcineurin inhibitor elimination: The Kuwaiti experience
    • Johny KV, Nampoory MR, Hamid MH, et al. Low-dose sirolimus in combination with mycophenolate in calcineurin inhibitor elimination: the Kuwaiti experience. Transplant Proc 2003; 35: 2750.
    • (2003) Transplant Proc , vol.35 , pp. 2750
    • Johny, K.V.1    Nampoory, M.R.2    Hamid, M.H.3
  • 56
    • 0036154082 scopus 로고    scopus 로고
    • Open Randomized Trial Comparing Early Withdrawal of either Cyclosporine or Mycophenolate Mofetil in Stable Renal Transplant Recipients Initially Treated with a Triple Drug Regimen
    • Schnuelle P, van der Heide JH, Tegzess A, et al. Open Randomized Trial Comparing Early Withdrawal of either Cyclosporine or Mycophenolate Mofetil in Stable Renal Transplant Recipients Initially Treated with a Triple Drug Regimen. J Am Soc Nephrol 2002; 13: 536.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 536
    • Schnuelle, P.1    Van Der Heide, J.H.2    Tegzess, A.3
  • 57
    • 0037623516 scopus 로고    scopus 로고
    • Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience
    • Morelon E, Kreis H. Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience. Transplant Proc 2003; 35: 52S.
    • (2003) Transplant Proc , vol.35
    • Morelon, E.1    Kreis, H.2
  • 58
    • 2942562298 scopus 로고    scopus 로고
    • Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy
    • Dittrich E, Schmaldienst S, Soleiman A, et al. Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy. Transplant Int 2004; 17: 215.
    • (2004) Transplant Int , vol.17 , pp. 215
    • Dittrich, E.1    Schmaldienst, S.2    Soleiman, A.3
  • 59
    • 8644289235 scopus 로고    scopus 로고
    • Investigation of pediatric renal transplant recipients with heavy proteinuria after sirolimus rescue
    • Butani L. Investigation of pediatric renal transplant recipients with heavy proteinuria after sirolimus rescue. Transplantation 2004; 78: 1362.
    • (2004) Transplantation , vol.78 , pp. 1362
    • Butani, L.1
  • 60
    • 27844461589 scopus 로고    scopus 로고
    • Proteinuria developing after clinical islet transplantation resolves with sirolimus withdrawal and increased tacrolimus dosing
    • Senior PA, Paty BW, Cockfield SM, et al. Proteinuria developing after clinical islet transplantation resolves with sirolimus withdrawal and increased tacrolimus dosing. Am J Transplant 2005; 5: 2318.
    • (2005) Am J Transplant , vol.5 , pp. 2318
    • Senior, P.A.1    Paty, B.W.2    Cockfield, S.M.3
  • 61
    • 31544461508 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: Changes in glomerular haemodynamics and proteinuria
    • Saurina A, Campistol JM, Piera C, et al. Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: changes in glomerular haemodynamics and proteinuria. Nephrol Dial Transplant 2006; 21: 488.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 488
    • Saurina, A.1    Campistol, J.M.2    Piera, C.3
  • 62
    • 0023854871 scopus 로고
    • The long-term course of cyclosporine-associated chronic nephropathy
    • Myers BD, Sibley R, Newton L et al. The long-term course of cyclosporine-associated chronic nephropathy. Kidney Int 1988; 33: 590.
    • (1988) Kidney Int , vol.33 , pp. 590
    • Myers, B.D.1    Sibley, R.2    Newton, L.3
  • 63
    • 0038666511 scopus 로고    scopus 로고
    • Sirolimus Prolongs Recovery from Delayed Graft Function after Cadaveric Renal Transplantation
    • McTaggart RA, Gottlieb D, Brooks J, et al. Sirolimus Prolongs Recovery from Delayed Graft Function After Cadaveric Renal Transplantation. Am J Transplant 2003; 3: 416.
    • (2003) Am J Transplant , vol.3 , pp. 416
    • McTaggart, R.A.1    Gottlieb, D.2    Brooks, J.3
  • 64
    • 2442442944 scopus 로고    scopus 로고
    • Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies
    • Fervenza FC, Fitzpatrick PM, Mertz J, et al. Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies. Nephrol Dial Transplant 2004; 19: 1288.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 1288
    • Fervenza, F.C.1    Fitzpatrick, P.M.2    Mertz, J.3
  • 65
    • 0035881897 scopus 로고    scopus 로고
    • Proteinuria after renal transplantation affects not only graft survival but also patient survival
    • Roodnat JI, Mulder PG, Rischen-Vos J, et al. Proteinuria after renal transplantation affects not only graft survival but also patient survival. Transplantation 2001; 72: 438.
    • (2001) Transplantation , vol.72 , pp. 438
    • Roodnat, J.I.1    Mulder, P.G.2    Rischen-Vos, J.3
  • 66
    • 0033774719 scopus 로고    scopus 로고
    • A Meta-Analysis of Immunosuppression Withdrawal Trials in Renal Transplantation
    • Kasiske BL, Chakkera HA, Louis TA, Ma JZ. A Meta-Analysis of Immunosuppression Withdrawal Trials in Renal Transplantation. J Am Soc Nephrol 2000; 11: 1910.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1910
    • Kasiske, B.L.1    Chakkera, H.A.2    Louis, T.A.3    Ma, J.Z.4
  • 67
    • 0035884710 scopus 로고    scopus 로고
    • Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure
    • Johnson RW, Kreis H, Oberbauer R, et al. Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. Transplantation 2001; 72: 777.
    • (2001) Transplantation , vol.72 , pp. 777
    • Johnson, R.W.1    Kreis, H.2    Oberbauer, R.3
  • 68
    • 0042768010 scopus 로고    scopus 로고
    • Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: Incidence, risk factors, progression, and prognosis
    • Chueh SC, Kahan BD. Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: incidence, risk factors, progression, and prognosis. Transplantation 2003; 76: 375.
    • (2003) Transplantation , vol.76 , pp. 375
    • Chueh, S.C.1    Kahan, B.D.2
  • 69
    • 0038640978 scopus 로고    scopus 로고
    • Influence of hypercholesterolemia on patient and graft survival in recipients of kidney transplants
    • Booth JC, Joseph JT, Jindal RM. Influence of hypercholesterolemia on patient and graft survival in recipients of kidney transplants. Clinical Transplant 2003; 17: 101.
    • (2003) Clinical Transplant , vol.17 , pp. 101
    • Booth, J.C.1    Joseph, J.T.2    Jindal, R.M.3
  • 70
    • 0034720044 scopus 로고    scopus 로고
    • Cholesterol as an independent predictor of outcome after renal transplantation
    • Roodnat JI, Mulder PG, Zietse R, et al. Cholesterol as an independent predictor of outcome after renal transplantation. Transplantation 2000; 69: 1704.
    • (2000) Transplantation , vol.69 , pp. 1704
    • Roodnat, J.I.1    Mulder, P.G.2    Zietse, R.3
  • 71
  • 72
    • 0036664390 scopus 로고    scopus 로고
    • Effects of sirolimus on lipids in renal allograft recipients: An analysis using the Framingham risk model
    • Blum CB. Effects of sirolimus on lipids in renal allograft recipients: an analysis using the Framingham risk model. Am J Transplant 2002; 2: 551.
    • (2002) Am J Transplant , vol.2 , pp. 551
    • Blum, C.B.1
  • 73
    • 27644436740 scopus 로고    scopus 로고
    • Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
    • Kauffman HM, Cherikh WS, Cheng Y, et al. Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 2005; 80: 883.
    • (2005) Transplantation , vol.80 , pp. 883
    • Kauffman, H.M.1    Cherikh, W.S.2    Cheng, Y.3
  • 74
    • 31044452076 scopus 로고    scopus 로고
    • Available at Accessed September 21, 2006
    • USRDS Annual Data Report, 2005. Available at http://www.usrds.org/2005/ pdf/07_tx_05.pdf. Accessed September 21, 2006.
    • (2005) USRDS Annual Data Report
  • 75
    • 0036523936 scopus 로고    scopus 로고
    • Call for revolution: A new approach to describing allograft deterioration
    • Halloran PF. Call for revolution: A new approach to describing allograft deterioration. Am J Transplant 2002; 2: 195.
    • (2002) Am J Transplant , vol.2 , pp. 195
    • Halloran, P.F.1


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