Early Sirolimus Use With Cyclosporine Elimination Does Not Induce Progressive Proteinuria

Transplantation Proceedings

Volumn 39, Issue 7, 2007, Pages 2151-2152

  Ruiz, J C ^a   Campistol, J M ^b   Sanchez Fructuoso, A ^c   Mota, A ^d   Grinyo, J M ^e   Paul, J ^f   Castro Henriques, A ^g   Reimao Pinto, J ^h   Garcia, J ⁱ   Morales, J M ^j   Granados, E ^k   Arias, M ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

^c HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^d CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^e HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^f HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

^g HOSPITAL DE SANTO ANTÓNIO   (Portugal)

^h HOSPITAL CURRY CABRAL   (Portugal)

ⁱ HOSPITAL UNIVERSITARIO LA FE   (Spain)

^j HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^k SA   (Spain)

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Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; RAPAMYCIN;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELAYED GRAFT FUNCTION; DEMOGRAPHY; DRUG WITHDRAWAL; FOLLOW UP; GLOMERULUS FILTRATION RATE; GRAFT VERSUS HOST REACTION; HEMODYNAMICS; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PRIORITY JOURNAL; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL;

CYCLOSPORINE; GLOMERULAR FILTRATION RATE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; PROTEINURIA; SIROLIMUS;

EID: 34548685354     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.06.054     Document Type: Article

References (8)

1. Ruiz J.C., Campistol J.M., Sanchez-Fructuoso A., et al. Increase of proteinuria after conversion from calcineurin inhibitor to sirolimus-based treatment in kidney transplant patients with chronic allograft dysfunction. Nephrol Dial Transplant 21 (2006) 3252
2. Aliabadi A.Z., Kammerstätter D.P., Seebacher G., et al. Development of proteinuria after switch to sirolimus based immunosuppression in long-term cardiac transplant patients. Transplantation 82 suppl 3 (2006) 562
3. Letavernier E., Pe'raldi M.N., Pariente A., et al. Proteinuria following a switch from calcineurin inhibitors to sirolimus. Transplantation 80 (2005) 1198
4. Saurina A., Campistol J.M., Piera C., et al. Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: changes in glomerular haemodynamics and proteinuria. Nephrol Dial Transplant 21 (2006) 488
5. Johnson R.W., Kreis H., Oberbauer R., et al. Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. Transplantation 72 (2001) 777
6. Oberbauer R., Kreis H., Johnson R.W., et al. Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients: 2-year results of the Rapamune Maintenance Regimen Study. Transplantation 76 (2003) 364
7. Oberbauer R., Segoloni G., Campistol J.M., et al. Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation. Transpl Int 18 (2005) 22
8. Mota A., Arias M., Taskinen E.I., et al. Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years. Am J Transplant 4 (2004) 953