Generation of functional hepatocytes from mouse germ line cell-derived pluripotent stem cells in vitro

Stem Cells and Development

Volumn 19, Issue 8, 2010, Pages 1183-1194

  Fagoonee, Sharmila ^a   Hobbs, Robin M ^b   De Chiara, Letizia ^a   Cantarella, Daniela ^a   Piro, Rosario M ^a   Tolosano, Emanuela ^a   Medico, Enzo ^a   Provero, Paolo ^a   Pandolfi, Pier Paolo ^a,b   Silengo, Lorenzo ^a   Altruda, Fiorella ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; GLYCOGEN; HAPTOGLOBIN; INDOCYANINE GREEN; UREA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL THERAPY; CONTROLLED STUDY; DNA MICROARRAY; FETUS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GERM LINE; IN VITRO STUDY; LIVER CELL; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN SECRETION; UREA CYCLE;

ALPHA-FETOPROTEINS; ANIMALS; ANTIGENS, CD15; APOFERRITINS; CADHERINS; CELL COUNT; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CHOLESTEROL 7-ALPHA-HYDROXYLASE; DNA-BINDING PROTEINS; EMBRYOID BODIES; EMBRYONIC STEM CELLS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GERM CELLS; HAPTOGLOBINS; HEPATOCYTES; HOMEODOMAIN PROTEINS; INSULIN-LIKE GROWTH FACTOR I; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; OCTAMER TRANSCRIPTION FACTOR-3; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLURIPOTENT STEM CELLS; SERUM ALBUMIN; SERUM AMYLOID A PROTEIN; SPERMATOGONIA; TRANSCRIPTION FACTORS; UREA;

EID: 77955440543     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2009.0496     Document Type: Article

References (41)

1. Kawashita Y , C Guha , K Yamanouchi , Y Ito , Y Kamohara and T Kanematsu. (2005). Liver repopulation: a new concept of hepatocyte transplantation. Surg Today 35 : 705-710 .
2. Snykers S , J De Kock , V Rogiers and T Vanhaecke. (2009). In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art. Stem Cells 27 : 577-605 .
3. Duncan AW , C Dorrell and M Grompe. (2009). Stem cells and liver regeneration. Gastroenterology 137 : 466-481 .
4. Carvalho KA , CC Cury , L Oliveira , RI Cattaned , M Malvezzi , JC Francisco , A Pachalok , M Olandoski , JR Faria-Neto and LC Guarita-Souza. (2008). Evaluation of bone marrow mesenchymal stem cell standard cryopreservation procedure effi - ciency. Transplant Proc 40 : 839-841 .
5. Fuller R and RV Devireddy. (2008). The effect of two different freezing methods on the immediate post-thaw membrane integrity of adipose tissue derived stem cells. Int J Heat Mass Tran 51 : 5650-5654 .
6. Seandel M , D James , SV Shmelkov , I Falciatori , J Kim , S Chavala , DS Scherr , F Zhang , R Torres , NW Gale , GD Yancopoulos , A Murphy , DM Valenzuela , RM Hobbs , PP Pandolfi and S Rafii. (2007). Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature 449 : 346-350 .
7. Conrad S , M Renninger , J Hennenlotter , T Wiesner , L Just , M Bonin , W Aicher , HJ Buhring , U Mattheus , A Mack , HJ Wagner , S Minger , M Matzkies , M Reppel , J Hescheler , KD Sievert , A Stenzl and T Skutella. (2008). Generation of pluripotent stem cells from adult human testis. Nature 456 : 344-349 .
8. Golestaneh N , M Kokkinaki , D Pant , J Jiang , D DeStefano , C Fernandez-Bueno , JD Rone , BR Haddad , GI Gallicano and M Dym. (2009). Pluripotent stem cells derived from adult human testes. Stem Cells Dev 18 : 1115-1126 .
9. Kossack N , J Meneses , S Shefi , HN Nguyen , S Chavez , C Nicholas , J Gromoll , PJ Turek and RA Reijo-Pera. (2009). Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells. Stem Cells 27 : 138-149 .
10. Guan K , K Nayernia , LS Maier , S Wagner , R Dressel , JH Lee , J Nolte , F Wolf , M Li , W Engel and G Hasenfuss. (2006). Pluripotency of spermatogonial stem cells from adult mouse testis. Nature 440 : 1199-1203 .
11. Ko K , N Tapia , G Wu , JB Kim , MJ Bravo , P Sasse , T Glaser , D Ruau , DW Han , B Greber , K Hausdorfer , V Sebastiano , M Stehling , BK Fleischmann , O Brustle , M Zenke and HR Scholer. (2009). Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell 5 : 87-96 .
12. Kanatsu-Shinohara M , K Inoue , J Lee , M Yoshimoto , N Ogonuki , H Miki , S Baba , T Kato , Y Kazuki , S Toyokuni , M Toyoshima , O Niwa , M Oshimura , T Heike , T Nakahata , F Ishino , A Ogura and T Shinohara. (2004). Generation of pluripotent stem cells from neonatal mouse testis. Cell 119 : 1001-1112 .
13. de Rooij DG and SC Mizrak. (2008). Deriving multipotent stem cells from mouse spermatogonial stem cells: a new tool for developmental and clinical research. Development 135 : 2207-2213 .
14. Guan K , S Wagner , B Unsold , LS Maier , D Kaiser , B Hemmerlein , K Nayernia , W Engel and G Hasenfuss. (2007). Generation of functional cardiomyocytes from adult mouse spermatogonial stem cells. Circ Res 100 : 1615-1625 .
15. Streckfuss-Bomeke K , A Vlasov , S Hulsmann , D Yin , K Nayernia , W Engel , G Hasenfuss and K Guan. (2009). Generation of functional neurons and glia from multipotent adult mouse germline stem cells. Stem Cell Res 2 : 139-154 .
16. Huang YH , CC Chin , HN Ho , CK Chou , CN Shen , HC Kuo , TJ Wu , YC Wu , YC Hung , CC Chang and TY Ling. (2009). Pluripotency of mouse spermatogonial stem cells maintained by IGF-1-dependent pathway. FASEB J 23 : 2076-2087 .
17. Loya K , R Eggenschwiler , K Ko , M Sgodda , F Andre , M Bleidissel , HR Scholer and T Cantz. (2009). Hepatic differentiation of pluripotent stem cells. Biol Chem 390 : 1047-1055 .
18. Kanatsu-Shinohara M , T Muneto , J Lee , M Takenaka , S Chuma , N Nakatsuji , T Horiuchi and T Shinohara. (2008). Long-term culture of male germline stem cells from hamster testes. Biol Reprod 78 : 611-617 .
19. Choi D , HJ Lee , S Jee , S Jin , SK Koo , SS Paik , SC Jung , SY Hwang , KS Lee and B Oh. (2005). In vitro differentiation of mouse embryonic stem cells: enrichment of endodermal cells in the embryoid body. Stem Cells 23 : 817-827 .
20. Chinzei R , Y Tanaka , K Shimizu-Saito , Y Hara , S Kakinuma , M Watanabe , K Teramoto , S Arii , K Takase , C Sato , N Terada and H Teraoka. (2002). Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes. Hepatology 36 : 22-29 .
21. Amicone L , FM Spagnoli , G Spath , S Giordano , C Tommasini , S Bernardini , V De Luca , C Della Rocca , MC Weiss , PM Comoglio and M Tripodi. (1997). Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes. EMBO J 16 : 495-503 .
22. Klaunig JE , PJ Goldblatt , DE Hinton , MM Lipsky , J Chacko and BF Trump. (1981). Mouse liver cell culture. I. Hepatocyte isolation. In Vitro 17 : 913-925 .
23. Fagoonee S , F Di Cunto , D Vozzi , S Volinia , M Pellegrino , P Gasparini , L Silengo , F Altruda and E Tolosano. (2006). Microarray and large-scale in silico-based identifi cation of genes functionally related to haptoglobin and/or hemopexin. DNA Cell Biol 25 : 323-330 .
24. Amendola M , MA Venneri , A Biffi , E Vigna and L Naldini. (2005). Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. Nat Biotechnol 23 : 108-116 .
25. Vigna E , S Cavalieri , L Ailles , M Geuna , R Loew , H Bujard and L Naldini. (2002). Robust and effi cient regulation of transgene expression in vivo by improved tetracycline-dependent lentiviral vectors. Mol Ther 5 : 252-261 .
26. Fagoonee S , J Gburek , E Hirsch , S Marro , SK Moestrup , JM Laurberg , EI Christensen , L Silengo , F Altruda and E Tolosano. (2005). Plasma protein haptoglobin modulates renal iron loading. Am J Pathol 166 : 973-983 .
27. Zhou QJ , YD Huang , LX Xiang , JZ Shao , GS Zhou , H Yao , LC Dai and YL Lu. (2007). In vitro differentiation of embryonic stem cells into hepatocytes induced by fi broblast growth factors and bone morphological protein-4. Int J Biochem Cell Biol 39 : 1714-1721 .
28. Fu L and E Medico. (2007). FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data. BMC Bioinformatics 8 : 3 .
29. Ashburner M , CA Ball , JA Blake , D Botstein , H Butler , JM Cherry , AP Davis , K Dolinski , SS Dwight , JT Eppig , MA Harris , DP Hill , L Issel-Tarver , A Kasarskis , S Lewis , JC Matese , JE Richardson , M Ringwald , GM Rubin and G Sherlock. (2000). Gene ontology: tool for the unifi cation of biology. The Gene Ontology Consortium. Nat Genet 25 : 25-29 .
30. Kanehisa M , M Araki , S Goto , M Hattori , M Hirakawa , M Itoh , T Katayama , S Kawashima , S Okuda , T Tokimatsu and Y Yamanishi. (2008). KEGG for linking genomes to life and the environment. Nucleic Acids Res 36 (Database issue): D480-D484 .
31. Kanehisa M and S Goto. (2000). KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28 : 27-30 .
32. Watanabe T , K Nakagawa , S Ohata , D Kitagawa , G Nishitai , J Seo , S Tanemura , N Shimizu , H Kishimoto , T Wada , J Aoki , H Arai , T Iwatsubo , M Mochita , T Watanabe , M Satake , Y Ito , T Matsuyama , TW Mak , JM Penninger , H Nishina and T Katada. (2002). SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis. Dev Biol 250 : 332-347 .
33. Guo Y , X Zhang , J Huang , Y Zeng , W Liu , C Geng , KW Li , D Yang , S Wu , H Wei , Z Han , X Qian , Y Jiang and F He. (2009). Relationships between hematopoiesis and hepatogen- esis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profi les. PLoS ONE 4 : e7641 .
34. Li K , SH Sacks and W Zhou. (2007). The relative importance of local and systemic complement production in ischaemia, transplantation and other pathologies. Mol Immunol 44 : 3866-3874 .
35. Boost KA , MK Auth , D Woitaschek , HS Kim , P Hilgard , S Nadalin and RA Blaheta. (2007). Long-term production of major coagulation factors and inhibitors by primary human hepatocytes in vitro: perspectives for clinical application. Liver Int 27 : 832-844 .
36. Enns GM and MT Millan. (2008). Cell-based therapies for metabolic liver disease. Mol Genet Metab 95 : 3-10 .
37. Kanatsu-Shinohara M , J Lee , K Inoue , N Ogonuki , H Miki , S Toyokuni , M Ikawa , T Nakamura , A Ogura and T Shinohara. (2008). Pluripotency of a single spermatogonial stem cell in mice. Biol Reprod 78 : 681-687 .
38. Chin MH , MJ Mason , W Xie , S Volinia , M Singer , C Peterson , G Ambartsumyan , O Aimiuwu , L Richter , J Zhang , I Khvorostov , V Ott , M Grunstein , N Lavon , N Benvenisty , CM Croce , AT Clark , T Baxter , AD Pyle , MA Teitell , M Pelegrini , K Plath and WE Lowry. (2009). Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell 5 : 111-123 .
39. Oh SH , YH Jung , MK Gupta , SJ Uhm and HT Lee. (2009). H19 gene is epigenetically stable in mouse multipotent germline stem cells. Mol Cells 27 : 635-640 .
40. Oertel M , A Menthena , YQ Chen , B Teisner , CH Jensen and DA Shafritz. (2008). Purifi cation of fetal liver stem/progenitor cells containing all the repopulation potential for normal adult rat liver. Gastroenterology 134 : 823-832 .
41. Sandhu JS , PM Petkov , MD Dabeva and DA Shafritz. (2001). Stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cells. Am J Pathol 159 : 1323-1334 .