The structure?activity relationship of the 3-Oxy site in the anticonvulsant (R)- N -benzyl 2-acetamido-3-methoxypropionamide

Journal of Medicinal Chemistry

Volumn 53, Issue 15, 2010, Pages 5716-5726

  Morieux, Pierre ^a   Salomé, Christophe ^a   Park, Ki Duk ^a   Stables, James P ^b   Kohn, Harold ^a,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HARKOSERIDE; N BENZYL 2 ACETAMIDO 3 (2 ACETAMIDOETHOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (2 CYCLOHEXYLMETHOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (2 CYCLOHEXYLOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (2 CYCLOPROPYLETHOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (2 METHOXYETHOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (3 OXOPROPOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (BENZYLOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (BUT 2 YN 1 YLOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (BUT 3 ENYLOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 (BUT 3 YNYLOXY)PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 [2 (3 METHYL 3H DIAZIRIN 3 YL)ETHOXY]PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 [2 (OXIRAN 2 YL)ETHOXY]PROPIONAMIDE; N BENZYL 2 ACETAMIDO 3 PHENETHOXYPROPIONAMIDE; PHENOBARBITAL; PHENYTOIN; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; ELECTRIC SHOCK; HYDROPHOBICITY; MOUSE; NONHUMAN; RAT; RODENT; SEIZURE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ACETAMIDES; ANIMALS; ANTICONVULSANTS; ELECTROSHOCK; HYDROPHOBICITY; MALE; MICE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77955437092     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100508m     Document Type: Article

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