High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometric analysis for small molecules in plasma

Analytical Chemistry

Volumn 75, Issue 13, 2003, Pages 3122-3127

  Hsieh, Yunsheng ^a   Merkle, Kara ^b   Wang, Ganfeng ^a   Brisson, Jean Marc ^a   Korfmacher, Walter A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b APPLIED BIOSYSTEMS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATMOSPHERIC PRESSURE; MASS SPECTROMETRY; MOLECULAR DYNAMICS; PHARMACOKINETICS; PHOTOIONIZATION;

ATMOSPHERIC PRESSURE PHOTOIONIZATION (APPI);

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CLOZAPINE; DRUG; LONAFARNIB;

ANIMAL EXPERIMENT; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG INFUSION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; IONIZATION; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; ATMOSPHERIC PRESSURE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLOZAPINE; DRUG EVALUATION, PRECLINICAL; DRUGS, INVESTIGATIONAL; MASS SPECTROMETRY; PHOTOCHEMISTRY; PIPERIDINES; PYRIDINES; RATS;

EID: 0038337980     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac0300082     Document Type: Article

References (18)

1. Plumb, R. S.; Dear, G. J.; Higton, D. N.; Mallett, D. M.; Pleasance, S.; Biddlecombe R. A. Xenobiotica 2001, 31, 599.
2. Hsieh, Y.; Chintala, M.; Mei, H.; Agans, J.; Brisson, J.; Ng, K.; Korfmacher, W. A. Rapid Commun. Mass Spectrom. 2001, 15, 2481.
3. Miller-Stein, C.; Bonfiglio, R.; Olah, T. V.; King, R. C. Am. Pharm. Rev. 2000, 3, 54.
4. Mei, H.; Hsieh, Y.; Nardo, C.; Xu, X.; Wang, S.; Ng, K.; Korfmacher, W. A. Rapid Commun. Mass Spectrom. 2003, 17, 97.
5. Matuszewski, B. K.; Constanzer M. L.; Chavez-Eng, C. M. Anal. Chem. 1998, 70, 882.
6. Cox, K. A.; Clarke, N.; Ridgen, D.; Korfmacher, W. A. Am. Pharm. Rev. 2001, 4, 45.
7. Robb, D. B.; Covey, T. R.; Bruins, A. P. Anal. Chem. 2000, 72, 365.
8. Alary, J.; Berthemy, A.; Tuong, A.; Uzabiaga, M. Procedings of the 50th ASMS Conference on Mass Spectrometry and Allied Topics, 2002.
9. Yang, C.; Henion, J. J. Chromatogr., A 2002, 970, 155.
10. Liu, M.; Bryant, M. S.; Chen, J.; Lee, S.; Yaremko, B.; Lipari, P.; Malkowski, M.; Ferrari, E.; Nielsen, L.; Prioli, N.; Dell, J.; Sinha, D.; Syed, J.; Korfmacher, W.; Nomeir, A.; Lin, C.; Wang, L.; Taveras, A.; Doll, R.; Njoroge, G.; Mallams, A.; Remiszewski, S.; Catino, J.; Girijavallabhan, V.; Kirschmeier, P.; Bishop, R. Cancer Res. 1998, 58, 4947.
11. Korfmacher, W. A.; Cox, K. A.; Veals, J.; K. Ng, K.; Hsieh, Y.; Wainhaus, S.; Broske, L.; Prelusky, D.; Nomeir, A.; White. R. E. Rapid Commun. Mass Spectrom. 2001, 15, 335.
12. Wit, J. S.; Jorgenson, J. W. J. Chromatogr. 1987. 411, 201.
13. Rauha, J.; Vuorela H.; Kostianinen, R. J. Mass Spectrom. 2001, 36, 1269.
14. Leinonen, A.; Kuuranne, T.; Kostiainen, R. J. Mass Spectrom. 2002, 37, 693.
15. Bonfiglio, R.; King, R. C.; Olah, T. V.; Merkle, K. Rapid Commun. Mass Spectrom. 1999, 13, 175.
16. King, R.; Bonfiglio, R.; Fernandez-Metzler, C.: Miller-Stein, C.; Olah, T.J. Am. Soc. Mass Spectrom. 2000, 11, 942.
17. Wang, G.; Hsieh, Y.; Cheng, K.-C.; Ng, K.; Korfmacher, W. A. Spectrosc. Int. J. 2003, 17, 511.
18. Hsieh, Y.; Brisson J.; Wang, G.; Ng, K.; Korfmacher, W. A. J. Pharm. Biomed. Anal., in press.