메뉴 건너뛰기




Volumn 9, Issue 13, 2010, Pages 2663-2673

The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors

Author keywords

BMI1; Breast cancer; c Myc; EZH2; HDAC inhibitors; p57; PcG proteins

Indexed keywords

BMI1 PROTEIN; HISTONE DEACETYLASE INHIBITOR; HISTONE LYSINE METHYLTRANSFERASE; POLYCOMB GROUP PROTEIN;

EID: 77955435095     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.13.12147     Document Type: Article
Times cited : (66)

References (54)
  • 1
    • 33845799903 scopus 로고    scopus 로고
    • Polycomb silencing mechanisms and the management of genomic programmes
    • DOI 10.1038/nrg1981, PII NRG1981
    • Schwartz YB, Pirrotta V. Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet 2007; 8:9-22. (Pubitemid 46006046)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.1 , pp. 9-22
    • Schwartz, Y.B.1    Pirrotta, V.2
  • 2
    • 70349469565 scopus 로고    scopus 로고
    • Mechanisms of polycomb gene silencing: Knowns and unknowns
    • Simon JA, Kingston RE. Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 2009; 10:697-708.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 3
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • DOI 10.1038/nrc1991, PII NRC1991
    • Sparmann A, van Lohuizen M. Polycomb silencers control cell fate, development and cancer. Nat Rev 2006; 6:846-56. (Pubitemid 44629896)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    Van Lohuizen, M.2
  • 4
    • 33744905801 scopus 로고    scopus 로고
    • The role of polycomb group proteins in cell cycle regulation during development
    • Martinez AM, Cavalli G. The role of polycomb group proteins in cell cycle regulation during development. Cell Cycle 2006; 5:1189-97. (Pubitemid 43845379)
    • (2006) Cell Cycle , vol.5 , Issue.11 , pp. 1189-1197
    • Martinez, A.-M.1    Cavalli, G.2
  • 8
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • DOI 10.1172/JCI23412
    • Glinsky GV, Berezovska O, Glinskii AB. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005; 115:1503-21. (Pubitemid 40814659)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.6 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 9
    • 9244248707 scopus 로고    scopus 로고
    • Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer
    • Kim JH, Yoon SY, Jeong SH, Kim SY, Moon SK, Joo JH, et al. Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer. Breast 2004; 13:383-8.
    • (2004) Breast , vol.13 , pp. 383-388
    • Kim, J.H.1    Yoon, S.Y.2    Jeong, S.H.3    Kim, S.Y.4    Moon, S.K.5    Joo, J.H.6
  • 10
    • 33846211524 scopus 로고    scopus 로고
    • Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival
    • Kang MK, Kim RH, Kim SJ, Yip FK, Shin KH, Dimri GP, et al. Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival. Br J Cancer 2007; 96:126-33.
    • (2007) Br J Cancer , vol.96 , pp. 126-133
    • Kang, M.K.1    Kim, R.H.2    Kim, S.J.3    Yip, F.K.4    Shin, K.H.5    Dimri, G.P.6
  • 11
    • 33745685884 scopus 로고    scopus 로고
    • Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells
    • Song LB, Zeng MS, Liao WT, Zhang L, Mo HY, Liu WL, et al. Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells. Cancer Res 2006; 66:6225-32.
    • (2006) Cancer Res , vol.66 , pp. 6225-6232
    • Song, L.B.1    Zeng, M.S.2    Liao, W.T.3    Zhang, L.4    Mo, H.Y.5    Liu, W.L.6
  • 12
    • 25444532087 scopus 로고    scopus 로고
    • Death-from-cancer signatures and stem cell contribution to metastatic cancer
    • Glinsky GV. Death-from-cancer signatures and stem cell contribution to metastatic cancer. Cell Cycle 2005; 4:1171-5.
    • (2005) Cell Cycle , vol.4 , pp. 1171-1175
    • Glinsky, G.V.1
  • 13
    • 29144487990 scopus 로고    scopus 로고
    • Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
    • Cao R, Tsukada Y, Zhang Y. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol Cell 2005; 20:845-54.
    • (2005) Mol Cell , vol.20 , pp. 845-854
    • Cao, R.1    Tsukada, Y.2    Zhang, Y.3
  • 14
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 2002; 298:1039-43.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 15
    • 3042801308 scopus 로고    scopus 로고
    • SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
    • Cao R, Zhang Y. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol Cell 2004; 15:57-67.
    • (2004) Mol Cell , vol.15 , pp. 57-67
    • Cao, R.1    Zhang, Y.2
  • 16
    • 34250218900 scopus 로고    scopus 로고
    • Polycomb comes of age: Genome-wide profiling of target sites
    • Ringrose L. Polycomb comes of age: genome-wide profiling of target sites. Curr Opin Cell Biol 2007; 19:290-7.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 290-297
    • Ringrose, L.1
  • 17
    • 33846225576 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells
    • Fiskus W, Pranpat M, Balasis M, Herger B, Rao R, Chinnaiyan A, et al. Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells. Mol Cancer Ther 2006; 5:3096-104.
    • (2006) Mol Cancer Ther , vol.5 , pp. 3096-3104
    • Fiskus, W.1    Pranpat, M.2    Balasis, M.3    Herger, B.4    Rao, R.5    Chinnaiyan, A.6
  • 18
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • Minucci S, Pelicci PG. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nature Rev 2006; 6:38-51.
    • (2006) Nature Rev , vol.6 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 19
    • 34547897023 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • Glozak MA, Seto E. Histone deacetylases and cancer. Oncogene 2007; 26:5420-32.
    • (2007) Oncogene , vol.26 , pp. 5420-5432
    • Glozak, M.A.1    Seto, E.2
  • 20
    • 34547864236 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Molecular mechanisms of action
    • Xu WS, Parmigiani RB, Marks PA. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 2007; 26:5541-52.
    • (2007) Oncogene , vol.26 , pp. 5541-5552
    • Xu, W.S.1    Parmigiani, R.B.2    Marks, P.A.3
  • 21
    • 0842277812 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1
    • Gui CY, Ngo L, Xu WS, Richon VM, Marks PA. Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1. Proc Natl Acad Sci USA 2004; 101:1241-6.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1241-1246
    • Gui, C.Y.1    Ngo, L.2    Xu, W.S.3    Richon, V.M.4    Marks, P.A.5
  • 25
    • 33846850149 scopus 로고    scopus 로고
    • Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins
    • Guo WJ, Datta S, Band V, Dimri GP. Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins. Mol Biol Cell 2007; 18:536-46.
    • (2007) Mol Biol Cell , vol.18 , pp. 536-546
    • Guo, W.J.1    Datta, S.2    Band, V.3    Dimri, G.P.4
  • 26
    • 20844434815 scopus 로고    scopus 로고
    • The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription
    • Murray PJ. The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription. Proc Natl Acad Sci USA 2005; 102:8686-91.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8686-8691
    • Murray, P.J.1
  • 27
    • 35148858784 scopus 로고    scopus 로고
    • c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter
    • Jiang G, Espeseth A, Hazuda DJ, Margolis DM. c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter. J Virol 2007; 81:10914-23.
    • (2007) J Virol , vol.81 , pp. 10914-10923
    • Jiang, G.1    Espeseth, A.2    Hazuda, D.J.3    Margolis, D.M.4
  • 28
    • 0037441885 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: A new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression
    • Skov S, Rieneck K, Bovin LF, Skak K, Tomra S, Michelsen BK, et al. Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression. Blood 2003; 101:1430-8.
    • (2003) Blood , vol.101 , pp. 1430-1438
    • Skov, S.1    Rieneck, K.2    Bovin, L.F.3    Skak, K.4    Tomra, S.5    Michelsen, B.K.6
  • 29
    • 48749118821 scopus 로고    scopus 로고
    • De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc
    • Wang LG, Liu XM, Fang Y, Dai W, Chiao FB, Puccio GM, et al. De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc. Int J Oncol 2008; 33:375-80.
    • (2008) Int J Oncol , vol.33 , pp. 375-380
    • Wang, L.G.1    Liu, X.M.2    Fang, Y.3    Dai, W.4    Chiao, F.B.5    Puccio, G.M.6
  • 30
    • 21644464967 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor suberoylanilide hydroxamic acid downregulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines
    • Xu Y, Voelter-Mahlknecht S, Mahlknecht U. The histone deacetylase inhibitor suberoylanilide hydroxamic acid downregulates expression levels of Bcr-abl, c-Myc and HDAC3 in chronic myeloid leukemia cell lines. Int J Mol Med 2005; 15:169-72.
    • (2005) Int J Mol Med , vol.15 , pp. 169-172
    • Xu, Y.1    Voelter-Mahlknecht, S.2    Mahlknecht, U.3
  • 31
    • 1842861744 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock
    • Munro J, Barr NI, Ireland H, Morrison V, Parkinson EK. Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock. Exp Cell Res 2004; 295:525-38.
    • (2004) Exp Cell Res , vol.295 , pp. 525-538
    • Munro, J.1    Barr, N.I.2    Ireland, H.3    Morrison, V.4    Parkinson, E.K.5
  • 32
    • 0029778901 scopus 로고    scopus 로고
    • Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
    • Ogryzko VV, Hirai TH, Russanova VR, Barbie DA, Howard BH. Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol Cell Biol 1996; 16:5210-8.
    • (1996) Mol Cell Biol , vol.16 , pp. 5210-5218
    • Ogryzko, V.V.1    Hirai, T.H.2    Russanova, V.R.3    Barbie, D.A.4    Howard, B.H.5
  • 33
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 1995; 92:9363-7.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3    Acosta, M.4    Scott, G.5    Roskelley, C.6
  • 34
    • 34247625135 scopus 로고    scopus 로고
    • Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
    • Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, et al. Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Gene Dev 2007; 21:1050-63.
    • (2007) Gene Dev , vol.21 , pp. 1050-1063
    • Tan, J.1    Yang, X.2    Zhuang, L.3    Jiang, X.4    Chen, W.5    Lee, P.L.6
  • 35
    • 64549090667 scopus 로고    scopus 로고
    • CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells
    • Yang X, Karuturi RK, Sun F, Aau M, Yu K, Shao R, et al. CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. PLoS One 2009; 4:5011.
    • (2009) PLoS One , vol.4 , pp. 5011
    • Yang, X.1    Karuturi, R.K.2    Sun, F.3    Aau, M.4    Yu, K.5    Shao, R.6
  • 36
    • 25444446426 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors suppress the induction of c-Jun and its target genes including COX-2
    • Yamaguchi K, Lantowski A, Dannenberg AJ, Subbaramaiah K. Histone deacetylase inhibitors suppress the induction of c-Jun and its target genes including COX-2. J Biol Chem 2005; 280:32569-77.
    • (2005) J Biol Chem , vol.280 , pp. 32569-32577
    • Yamaguchi, K.1    Lantowski, A.2    Dannenberg, A.J.3    Subbaramaiah, K.4
  • 37
    • 33644836891 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells
    • Alao JP, Stavropoulou AV, Lam EW, Coombes RC, Vigushin DM. Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells. Mol Cancer 2006; 5:8.
    • (2006) Mol Cancer , vol.5 , pp. 8
    • Alao, J.P.1    Stavropoulou, A.V.2    Lam, E.W.3    Coombes, R.C.4    Vigushin, D.M.5
  • 38
    • 13944274571 scopus 로고    scopus 로고
    • Histone deacetylase inhibition downregulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding
    • Hu J, Colburn NH. Histone deacetylase inhibition downregulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding. Mol Cancer Res 2005; 3:100-9.
    • (2005) Mol Cancer Res , vol.3 , pp. 100-109
    • Hu, J.1    Colburn, N.H.2
  • 39
    • 51049117752 scopus 로고    scopus 로고
    • Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells
    • Zhou Q, Agoston AT, Atadja P, Nelson WG, Davidson NE. Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells. Mol Cancer Res 2008; 6:873-83.
    • (2008) Mol Cancer Res , vol.6 , pp. 873-883
    • Zhou, Q.1    Agoston, A.T.2    Atadja, P.3    Nelson, W.G.4    Davidson, N.E.5
  • 40
    • 33645826712 scopus 로고    scopus 로고
    • BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas
    • Nowak K, Kerl K, Fehr D, Kramps C, Gessner C, Killmer K, et al. BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas. Nucleic Acids Res 2006; 34:1745-54.
    • (2006) Nucleic Acids Res , vol.34 , pp. 1745-1754
    • Nowak, K.1    Kerl, K.2    Fehr, D.3    Kramps, C.4    Gessner, C.5    Killmer, K.6
  • 41
    • 20444370974 scopus 로고    scopus 로고
    • What has senescence got to do with cancer?
    • Dimri GP. What has senescence got to do with cancer? Cancer Cell 2005; 7:505-12.
    • (2005) Cancer Cell , vol.7 , pp. 505-512
    • Dimri, G.P.1
  • 42
    • 24344473755 scopus 로고    scopus 로고
    • Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2
    • Bali P, Pranpat M, Swaby R, Fiskus W, Yamaguchi H, Balasis M, et al. Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2. Clin Cancer Res 2005; 11:6382-9.
    • (2005) Clin Cancer Res , vol.11 , pp. 6382-6389
    • Bali, P.1    Pranpat, M.2    Swaby, R.3    Fiskus, W.4    Yamaguchi, H.5    Balasis, M.6
  • 43
    • 14044276343 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors downregulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas
    • Duan H, Heckman CA, Boxer LM. Histone deacetylase inhibitors downregulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas. Mol Cellular Biol 2005; 25:1608-19.
    • (2005) Mol Cellular Biol , vol.25 , pp. 1608-1619
    • Duan, H.1    Heckman, C.A.2    Boxer, L.M.3
  • 44
    • 22744437647 scopus 로고    scopus 로고
    • HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma
    • Singh TR, Shankar S, Srivastava RK. HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene 2005; 24:4609-23.
    • (2005) Oncogene , vol.24 , pp. 4609-4623
    • Singh, T.R.1    Shankar, S.2    Srivastava, R.K.3
  • 45
    • 0030812064 scopus 로고    scopus 로고
    • Regulation of apoptosis resistance and ontogeny of age-dependent diseases
    • Wang E. Regulation of apoptosis resistance and ontogeny of age-dependent diseases. Exp Geront 1997; 32:471-84.
    • (1997) Exp Geront , vol.32 , pp. 471-484
    • Wang, E.1
  • 47
    • 33947134834 scopus 로고    scopus 로고
    • The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
    • Bracken AP, Kleine-Kohlbrecher D, Dietrich N, Pasini D, Gargiulo G, Beekman C, et al. The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells. Gene Dev 2007; 21:525-30.
    • (2007) Gene Dev , vol.21 , pp. 525-530
    • Bracken, A.P.1    Kleine-Kohlbrecher, D.2    Dietrich, N.3    Pasini, D.4    Gargiulo, G.5    Beekman, C.6
  • 49
    • 0032589743 scopus 로고    scopus 로고
    • p57KIP2 expression and loss of heterozygosity during immortal conversion of cultured human mammary epithelial cells
    • Nijjar T, Wigington D, Garbe JC, Waha A, Stampfer MR, Yaswen P. p57KIP2 expression and loss of heterozygosity during immortal conversion of cultured human mammary epithelial cells. Cancer Res 1999; 59:5112-8.
    • (1999) Cancer Res , vol.59 , pp. 5112-5118
    • Nijjar, T.1    Wigington, D.2    Garbe, J.C.3    Waha, A.4    Stampfer, M.R.5    Yaswen, P.6
  • 50
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 2009; 138:592-603.
    • (2009) Cell , vol.138 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3    Lobo, N.4    Dalerba, P.5    Qian, D.6
  • 51
    • 34249325876 scopus 로고    scopus 로고
    • Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: C-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior
    • Dimri M, Naramura M, Duan L, Chen J, Ortega-Cava C, Chen G, et al. Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: c-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior. Cancer Res 2007; 67:4164-72.
    • (2007) Cancer Res , vol.67 , pp. 4164-4172
    • Dimri, M.1    Naramura, M.2    Duan, L.3    Chen, J.4    Ortega-Cava, C.5    Chen, G.6
  • 52
    • 43249130490 scopus 로고    scopus 로고
    • SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus
    • Kia SK, Gorski MM, Giannakopoulos S, Verrijzer CP. SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus. Mol Cell Biol 2008; 28:3457-64.
    • (2008) Mol Cell Biol , vol.28 , pp. 3457-3464
    • Kia, S.K.1    Gorski, M.M.2    Giannakopoulos, S.3    Verrijzer, C.P.4
  • 54
    • 35948990017 scopus 로고    scopus 로고
    • Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways
    • Datta S, Hoenerhoff MJ, Bommi P, Sainger R, Guo WJ, Dimri M, et al. Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways. Cancer Res 2007; 67:10286-95.
    • (2007) Cancer Res , vol.67 , pp. 10286-10295
    • Datta, S.1    Hoenerhoff, M.J.2    Bommi, P.3    Sainger, R.4    Guo, W.J.5    Dimri, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.