Chemoenzymatic synthesis of (2S,3S,4S)-form, the physiologically active stereoisomer of dehydroxymethylepoxyquinomicin (DHMEQ), a potent inhibitor on NF-κB

Tetrahedron

Volumn 66, Issue 35, 2010, Pages 7083-7087

  Hamada, Manabu ^a   Niitsu, Yukihiro ^a   Hiraoka, Chihiro ^a   Kozawa, Ikuko ^a   Higashi, Toshinori ^a   Shoji, Mitsuru ^a   Umezawa, Kazuo ^a   Sugai, Takeshi ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Asymmetric epoxidation; DHMEQ; Hydrolysis; Kinetic resolution; Lipase

Indexed keywords

ALDEHYDE; DEHYDROXYMETHYLEPOXYQUINOMICIN; LIPASE B;

ARTICLE; ASYMMETRIC SYNTHESIS; CATALYSIS; DRUG SYNTHESIS; ENANTIOMER; EPOXIDATION; HYDROLYSIS; PRIORITY JOURNAL; STEREOCHEMISTRY; STEREOISOMERISM;

BURKHOLDERIA CEPACIA;

EID: 77955425192     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.07.013     Document Type: Article

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