Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3β and mitochondrial permeability transition

Mitochondrion

Volumn 10, Issue 5, 2010, Pages 456-463

  Varela, Ana T ^a   Simões, Anabela M ^a   Teodoro, João S ^a   Duarte, Filipe V ^a   Gomes, Ana P ^a   Palmeira, Carlos M ^a   Rolo, Anabela P ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

ATP; GSK 3 ; Ischemia reperfusion; Mitochondria; MPT; Oxidative phosphorylation

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; ALKALOID; ASPARTATE AMINOTRANSFERASE; CYTOCHROME C; GLYCOGEN SYNTHASE KINASE 3BETA; INDIRUBIN 3' OXIME; LACTATE DEHYDROGENASE; PROTEIN BAX; SERINE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER HOMOGENATE; LIVER ISCHEMIA; LIVER MITOCHONDRION; LIVER PROTECTION; MALE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIMARY PREVENTION; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; REPERFUSION INJURY; REPOLARIZATION;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BCL-2-ASSOCIATED X PROTEIN; CYTOCHROMES C; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; INDOLES; L-LACTATE DEHYDROGENASE; LIVER; LIVER FUNCTION TESTS; MALE; MITOCHONDRIA; OXIMES; PERMEABILITY; RATS; RATS, WISTAR; REPERFUSION INJURY;

RATTUS NORVEGICUS;

EID: 77955424602     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2010.04.006     Document Type: Article

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