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Volumn 5, Issue 7, 2010, Pages

The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CRYPTOCHROME 2; OSTEOCALCIN; PER2 PROTEIN; TRAP5B PROTEIN; UNCLASSIFIED DRUG; CIRCADIAN RHYTHM SIGNALING PROTEIN; CRY2 PROTEIN, MOUSE; CRYPTOCHROME;

EID: 77955411128     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011527     Document Type: Article
Times cited : (97)

References (38)
  • 1
    • 0037194790 scopus 로고    scopus 로고
    • Coordination of circadian timing in mammals
    • doi:10.1038/nature00965
    • Reppert SM, Weaver DR (2002) Coordination of circadian timing in mammals. Nature 418: 935-41. doi:10.1038/nature00965
    • (2002) Nature , vol.418 , pp. 935-941
    • Reppert, S.M.1    Weaver, D.R.2
  • 2
    • 34547860503 scopus 로고    scopus 로고
    • Circadian clock: Time for a phase shift of ideas?
    • doi:10.1016/j.cub.2007.06.041
    • Merrow M, Roenneberg T (2007) Circadian clock: time for a phase shift of ideas? Curr Biol 17: R636-8. doi:10.1016/j.cub.2007.06.041.
    • (2007) Curr Biol , vol.17
    • Merrow, M.1    Roenneberg, T.2
  • 3
    • 50849136513 scopus 로고    scopus 로고
    • Cellular circadian pacemaking and the role of cytosolic rhythms
    • doi:10.1016/j.cub.2008.07.021
    • Hastings MH, Maywood ES, O'Neill JS (2008) Cellular circadian pacemaking and the role of cytosolic rhythms. Curr Biol 18: R805-R815. doi:10.1016/j.cub.2008.07.021.
    • (2008) Curr Biol , vol.18
    • Hastings, M.H.1    Maywood, E.S.2    O'Neill, J.S.3
  • 4
    • 0033536228 scopus 로고    scopus 로고
    • The mPer2 gene encodes a functional component of the mammalian circadian clock
    • doi:10.1038/22118
    • Zheng B, Larkin DW, Albrecht U, Sun ZS, Sage M, et al. (1999) The mPer2 gene encodes a functional component of the mammalian circadian clock. Nature 400: 169-73. doi:10.1038/22118.
    • (1999) Nature , vol.400 , pp. 169-173
    • Zheng, B.1    Larkin, D.W.2    Albrecht, U.3    Sun, Z.S.4    Sage, M.5
  • 5
    • 0033560863 scopus 로고    scopus 로고
    • Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
    • doi:10.1038/19323
    • van der Horst GT, Muijtjens M, Kobayashi K, Takano R, Kanno S, et al. (1999) Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. Nature 398: 627-630. doi:10.1038/19323.
    • (1999) Nature , vol.398 , pp. 627-630
    • van der Horst, G.T.1    Muijtjens, M.2    Kobayashi, K.3    Takano, R.4    Kanno, S.5
  • 6
    • 0034640253 scopus 로고    scopus 로고
    • Interacting molecular loops in the mammalian circadian clock
    • Shearman LP, Sriram S, Weaver DR, Maywood ES, Chaves I, et al. (2000) Interacting molecular loops in the mammalian circadian clock. Science 288: 1013-1019.
    • (2000) Science , vol.288 , pp. 1013-1019
    • Shearman, L.P.1    Sriram, S.2    Weaver, D.R.3    Maywood, E.S.4    Chaves, I.5
  • 8
    • 0037108057 scopus 로고    scopus 로고
    • Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant mice
    • doi:10.1101/gad.233702
    • Oster H, Yasui A, van der Horst GTJ, Albrecht U (2002) Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant mice. Genes Dev 16: 2633-8. doi:10.1101/gad.233702.
    • (2002) Genes Dev , vol.16 , pp. 2633-2638
    • Oster, H.1    Yasui, A.2    van der Horst, G.T.J.3    Albrecht, U.4
  • 9
    • 34247221543 scopus 로고    scopus 로고
    • Circadian oscillation of gene expression in murine calvarial bone
    • doi:10.1359/jbmr.061114
    • Zvonic S, Ptitsyn AA, Kilroy G, Wu X, Conrad SA, et al. (2007) Circadian oscillation of gene expression in murine calvarial bone. J Bone Miner Res 22: 357-365. doi:10.1359/jbmr.061114.
    • (2007) J Bone Miner Res , vol.22 , pp. 357-365
    • Zvonic, S.1    Ptitsyn, A.A.2    Kilroy, G.3    Wu, X.4    Conrad, S.A.5
  • 10
    • 41949095284 scopus 로고    scopus 로고
    • Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure
    • doi:10.1016/j.bone.2007.12.226
    • Wu X, Yu G, Parks H, Hebert T, Goh BC, et al. (2008) Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure. Bone 42: 861-870. doi:10.1016/j.bone.2007.12.226.
    • (2008) Bone , vol.42 , pp. 861-870
    • Wu, X.1    Yu, G.2    Parks, H.3    Hebert, T.4    Goh, B.C.5
  • 11
    • 45549109069 scopus 로고    scopus 로고
    • Systematic assessment of the human osteoblast transcriptome in resting and induced primary cells
    • doi:10.1152/physiolgenomics.00028.2008
    • Grundberg E, Brändström H, Lam KCL, Gurd S, Ge B, et al. (2008) Systematic assessment of the human osteoblast transcriptome in resting and induced primary cells. Physiol Genomics 33: 301-11. doi:10.1152/physiolgenomics.00028.2008.
    • (2008) Physiol Genomics , vol.33 , pp. 301-311
    • Grundberg, E.1    Brändström, H.2    Lam, K.C.L.3    Gurd, S.4    Ge, B.5
  • 12
    • 67650045545 scopus 로고    scopus 로고
    • The 4th dimension and adult stem cells: Can timing be everything?
    • doi:10.1002/jcb.22153
    • Gimble JM, Floyd ZE, Bunnell BA (2009) The 4th dimension and adult stem cells: Can timing be everything? J Cell Biochem 107: 569-578. doi:10.1002/jcb.22153.
    • (2009) J Cell Biochem , vol.107 , pp. 569-578
    • Gimble, J.M.1    Floyd, Z.E.2    Bunnell, B.A.3
  • 13
    • 0037020198 scopus 로고    scopus 로고
    • The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo
    • Fu L, Pelicano H, Liu J, Huang P, Lee C (2002) The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell 111: 41-50.
    • (2002) Cell , vol.111 , pp. 41-50
    • Fu, L.1    Pelicano, H.2    Liu, J.3    Huang, P.4    Lee, C.5
  • 14
    • 34247535799 scopus 로고    scopus 로고
    • Mutation of the circadian clock gene Per2 alters vascular endothelial function
    • doi:10.1161/CIRCULATIONAHA.106.653303
    • Viswambharan H, Carvas JM, Antic V, Marecic A, Jud C, et al. (2007) Mutation of the circadian clock gene Per2 alters vascular endothelial function. Circulation 115: 2188-95. doi:10.1161/CIRCULATIONAHA.106.653303.
    • (2007) Circulation , vol.115 , pp. 2188-2195
    • Viswambharan, H.1    Carvas, J.M.2    Antic, V.3    Marecic, A.4    Jud, C.5
  • 15
    • 13444254068 scopus 로고    scopus 로고
    • The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption
    • doi:10.1038/nm1163
    • Spanagel R, Pendyala G, Abarca C, Zghoul T, Sanchis-Segura C, et al. (2005) The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nat Med 11: 35-42. doi:10.1038/nm1163.
    • (2005) Nat Med , vol.11 , pp. 35-42
    • Spanagel, R.1    Pendyala, G.2    Abarca, C.3    Zghoul, T.4    Sanchis-Segura, C.5
  • 16
    • 33750026895 scopus 로고    scopus 로고
    • Lack of food anticipation in Per2 mutant mice
    • doi:10.1016/j.cub.2006.08.053
    • Feillet CA, Ripperger JA, Magnone MC, Dulloo A, Albrecht U, et al. (2006) Lack of food anticipation in Per2 mutant mice. Curr Biol 16: 2016-22. doi:10.1016/j.cub.2006.08.053.
    • (2006) Curr Biol , vol.16 , pp. 2016-2022
    • Feillet, C.A.1    Ripperger, J.A.2    Magnone, M.C.3    Dulloo, A.4    Albrecht, U.5
  • 17
    • 43049116816 scopus 로고    scopus 로고
    • Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood
    • doi:10.1016/j.cub.2008.04.012
    • Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, et al. (2008) Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol 18: 678-83. doi:10.1016/j.cub.2008.04.012.
    • (2008) Curr Biol , vol.18 , pp. 678-683
    • Hampp, G.1    Ripperger, J.A.2    Houben, T.3    Schmutz, I.4    Blex, C.5
  • 18
    • 33846115607 scopus 로고    scopus 로고
    • Differential effects of two period genes on the physiology and proteomic profiles of mouse anterior tibialis muscles
    • Bae K, Lee K, Seo Y, Lee H, Kim D, et al. (2006) Differential effects of two period genes on the physiology and proteomic profiles of mouse anterior tibialis muscles. Mol Cells 22: 275-84.
    • (2006) Mol Cells , vol.22 , pp. 275-284
    • Bae, K.1    Lee, K.2    Seo, Y.3    Lee, H.4    Kim, D.5
  • 19
    • 33746625139 scopus 로고    scopus 로고
    • The circadian clock Period 2 gene regulates gamma interferon production of NK cells in host response to lipopolysaccharide-induced endotoxic shock
    • doi:10.1128/IAI.00287-06
    • Liu J, Malkani G, Mankani G, Shi X, Meyer M, et al. (2006) The circadian clock Period 2 gene regulates gamma interferon production of NK cells in host response to lipopolysaccharide-induced endotoxic shock. Infect Immun 74: 4750-6. doi:10.1128/IAI.00287-06.
    • (2006) Infect Immun , vol.74 , pp. 4750-4756
    • Liu, J.1    Malkani, G.2    Mankani, G.3    Shi, X.4    Meyer, M.5
  • 20
    • 24144459585 scopus 로고    scopus 로고
    • The molecular clock mediates leptin-regulated bone formation
    • doi:10.1016/j.cell.2005.06.028
    • Fu L, Patel MS, Bradley A, Wagner EF, Karsenty G (2005) The molecular clock mediates leptin-regulated bone formation. Cell 122: 803-15. doi:10.1016/j.cell.2005.06.028.
    • (2005) Cell , vol.122 , pp. 803-815
    • Fu, L.1    Patel, M.S.2    Bradley, A.3    Wagner, E.F.4    Karsenty, G.5
  • 21
    • 43049101616 scopus 로고    scopus 로고
    • Serum levels of TRAP5b, a new bone resorption marker unaffected by renal dysfunction, as a useful marker of cortical bone loss in hemodialysis patients
    • doi:10.1007/s00223-008-9127-4
    • Shidara K, Inaba M, Okuno S, Yamada S, Kumeda Y, et al. (2008) Serum levels of TRAP5b, a new bone resorption marker unaffected by renal dysfunction, as a useful marker of cortical bone loss in hemodialysis patients. Calcif. Tissue Int 82: 278-287. doi:10.1007/s00223-008-9127-4.
    • (2008) Calcif. Tissue Int , vol.82 , pp. 278-287
    • Shidara, K.1    Inaba, M.2    Okuno, S.3    Yamada, S.4    Kumeda, Y.5
  • 22
    • 57249097079 scopus 로고    scopus 로고
    • Characterization of the bone phenotype in ClC-7-deficient mice
    • doi:10.1007/s00223-008-9185-7
    • Neutzsky-Wulff AV, Karsdal MA, Henriksen K (2008) Characterization of the bone phenotype in ClC-7-deficient mice. Calcif Tissue Int 83: 425-437. doi:10.1007/s00223-008-9185-7.
    • (2008) Calcif Tissue Int , vol.83 , pp. 425-437
    • Neutzsky-Wulff, A.V.1    Karsdal, M.A.2    Henriksen, K.3
  • 23
    • 42549150194 scopus 로고    scopus 로고
    • Low reproductive success in Per1 and Per2 mutant mouse females due to accelerated ageing?
    • doi:10.1530/REP-07-0434
    • Pilorz V, Steinlechner S (2008) Low reproductive success in Per1 and Per2 mutant mouse females due to accelerated ageing? Reproduction 135: 559-68. doi:10.1530/REP-07-0434.
    • (2008) Reproduction , vol.135 , pp. 559-568
    • Pilorz, V.1    Steinlechner, S.2
  • 25
    • 37449014336 scopus 로고    scopus 로고
    • Bone remodeling, energy metabolism, and the molecular clock
    • doi:10.1016/j.cmet.2007.12.004
    • Rosen CJ (2008) Bone remodeling, energy metabolism, and the molecular clock. Cell Metab 7: 7-10. doi:10.1016/j.cmet.2007.12.004.
    • (2008) Cell Metab , vol.7 , pp. 7-10
    • Rosen, C.J.1
  • 26
    • 34948910681 scopus 로고    scopus 로고
    • Central control of bone remodeling by neuromedin U
    • doi:10.1038/nm1640
    • Sato S, Hanada R, Kimura A, Abe T, Matsumoto T, et al. (2007) Central control of bone remodeling by neuromedin U. Nat Med 13: 1234-40. doi:10.1038/nm1640.
    • (2007) Nat Med , vol.13 , pp. 1234-1240
    • Sato, S.1    Hanada, R.2    Kimura, A.3    Abe, T.4    Matsumoto, T.5
  • 27
    • 53049106274 scopus 로고    scopus 로고
    • Neuromedin U directly stimulates growth of cultured rat calvarial osteoblast-like cells acting via the NMU receptor 2 isoform
    • Rucinski M, Ziolkowska A, Tyczewska M, Szyszka M, Malendowicz LK (2008) Neuromedin U directly stimulates growth of cultured rat calvarial osteoblast-like cells acting via the NMU receptor 2 isoform. Int J Mol Med 22: 363-368.
    • (2008) Int J Mol Med , vol.22 , pp. 363-368
    • Rucinski, M.1    Ziolkowska, A.2    Tyczewska, M.3    Szyszka, M.4    Malendowicz, L.K.5
  • 28
    • 11144353910 scopus 로고    scopus 로고
    • LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues
    • doi:10.1073/pnas.0308709101
    • Yoo S, Yamazaki S, Lowrey PL, Shimomura K, Ko CH, et al. (2004) PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A 101: 5339-46. doi:10.1073/pnas.0308709101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5339-5346
    • Yoo, S.1    Yamazaki, S.2    Lowrey, P.L.3    Shimomura, K.4    Ko, C.H.5
  • 29
    • 41949095284 scopus 로고    scopus 로고
    • Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure
    • doi:10.1016/j.bone.2007.12.226
    • Wu X, Yu G, Parks H, Hebert T, Goh BC, et al. (2008) Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure. Bone 42: 861-70. doi:10.1016/j.bone.2007.12.226.
    • (2008) Bone , vol.42 , pp. 861-870
    • Wu, X.1    Yu, G.2    Parks, H.3    Hebert, T.4    Goh, B.C.5
  • 30
    • 38049033068 scopus 로고    scopus 로고
    • Induction of circadian gene expression in human subcutaneous adipose-derived stem cells
    • doi:10.1038/oby.2007.308
    • Wu X, Zvonic S, Floyd ZE, Kilroy G, Goh BC, et al. (2007) Induction of circadian gene expression in human subcutaneous adipose-derived stem cells. Obesity (Silver Spring) 15: 2560-70. doi:10.1038/oby.2007.308.
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 2560-2570
    • Wu, X.1    Zvonic, S.2    Floyd, Z.E.3    Kilroy, G.4    Goh, B.C.5
  • 31
    • 65949123167 scopus 로고    scopus 로고
    • Clock-cancer connection in non-Hodgkin's lymphoma: A genetic association study and pathway analysis of the circadian gene cryptochrome 2
    • doi:10.1158/0008-5472.CAN-08-4572
    • Hoffman AE, Zheng T, Stevens RG, Ba Y, Zhang Y, et al. (2009) Clock-cancer connection in non-Hodgkin's lymphoma: a genetic association study and pathway analysis of the circadian gene cryptochrome 2. Cancer Res 69: 3605-3613. doi:10.1158/0008-5472.CAN-08-4572.
    • (2009) Cancer Res , vol.69 , pp. 3605-3613
    • Hoffman, A.E.1    Zheng, T.2    Stevens, R.G.3    Ba, Y.4    Zhang, Y.5
  • 32
    • 45749124735 scopus 로고    scopus 로고
    • RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice
    • doi:10.1172/JCI33392
    • Vaira S, Alhawagri M, Anwisye I, Kitaura H, Faccio R, et al. (2008) RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice. J Clin Invest 118: 2088-2097. doi:10.1172/JCI33392.
    • (2008) J Clin Invest , vol.118 , pp. 2088-2097
    • Vaira, S.1    Alhawagri, M.2    Anwisye, I.3    Kitaura, H.4    Faccio, R.5
  • 33
    • 0032506010 scopus 로고    scopus 로고
    • Dissociation between bone resorption and bone formation in osteopenic transgenic mice
    • Corral DA, Amling M, Priemel M, Loyer E, Fuchs S, et al. (1998) Dissociation between bone resorption and bone formation in osteopenic transgenic mice. Proc Natl Acad Sci U.S.A 95: 13835-13840.
    • (1998) Proc Natl Acad Sci U.S.A , vol.95 , pp. 13835-13840
    • Corral, D.A.1    Amling, M.2    Priemel, M.3    Loyer, E.4    Fuchs, S.5
  • 34
    • 34447132814 scopus 로고    scopus 로고
    • Skeletal remodeling in health and disease
    • doi:10.1038/nm1593
    • Zaidi M (2007) Skeletal remodeling in health and disease. Nat Med 13: 791-801. doi:10.1038/nm1593.
    • (2007) Nat Med , vol.13 , pp. 791-801
    • Zaidi, M.1
  • 35
    • 67349277390 scopus 로고    scopus 로고
    • Local communication on and within bone controls bone remodeling
    • doi:10.1016/j.bone.2009.03.671
    • Henriksen K, Neutzsky-Wulff AV, Bonewald LF, Karsdal MA (2009) Local communication on and within bone controls bone remodeling. Bone 44: 1026-1033. doi:10.1016/j.bone.2009.03.671.
    • (2009) Bone , vol.44 , pp. 1026-1033
    • Henriksen, K.1    Neutzsky-Wulff, A.V.2    Bonewald, L.F.3    Karsdal, M.A.4
  • 36
    • 0033303655 scopus 로고    scopus 로고
    • Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: Formal histomorphometric and biomechanical analyses
    • Amling M, Priemel M, Holzmann T, Chapin K, Rueger JM, et al. (1999) Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses. Endocrinology 140: 4982-7.
    • (1999) Endocrinology , vol.140 , pp. 4982-4987
    • Amling, M.1    Priemel, M.2    Holzmann, T.3    Chapin, K.4    Rueger, J.M.5
  • 37
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, et al. (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2: 595-610.
    • (1987) J Bone Miner Res , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5
  • 38
    • 33847234284 scopus 로고    scopus 로고
    • Intermittent administration of the circulating form of human parathyroid hormone (hPTH-1-37) prevents bone loss in ovariectomized rats
    • Stephan S, de Flierdt J, Loumi S, Bonaterra G, Kramer F, et al. (2007) Intermittent administration of the circulating form of human parathyroid hormone (hPTH-1-37) prevents bone loss in ovariectomized rats. EUROPEAN JOURNAL OF MEDICAL RESEARCH 12: 13-20.
    • (2007) EUROPEAN JOURNAL of MEDICAL RESEARCH , vol.12 , pp. 13-20
    • Stephan, S.1    de Flierdt, J.2    Loumi, S.3    Bonaterra, G.4    Kramer, F.5


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