메뉴 건너뛰기




Volumn 2, Issue 1, 2010, Pages 123-132

Management of metastatic renal cell carcinoma in patients with poor prognosis

Author keywords

Mammalian target of rapamycin (mTOR) inhibitors; Prognostic criteria; Renal cell carcinoma; Vascular endothelial growth factor (VEGF) pathway inhibitors

Indexed keywords

ALPHA INTERFERON; ALPHA2A INTERFERON; BEVACIZUMAB; BIOLOGICAL MARKER; CALCIUM; CARBONATE DEHYDRATASE IX; DOXORUBICIN; EVEROLIMUS; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR; HEMOGLOBIN; INTERLEUKIN 2; LACTATE DEHYDROGENASE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLACEBO; PROTEIN KINASE B; PROTEIN P53; SORAFENIB; SUNITINIB; TEMSIROLIMUS; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; VIMENTIN;

EID: 77955410487     PISSN: None     EISSN: 11791322     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (13)

References (59)
  • 2
    • 23744445106 scopus 로고    scopus 로고
    • Novel approaches in the therapy of metastatic renal cell carcinoma
    • Lam JS, Leppert JT, Belldegrun AS, Figlin RA. Novel approaches in the therapy of metastatic renal cell carcinoma. World J Urol. 2005;23(3):202-212.
    • (2005) World J Urol , vol.23 , Issue.3 , pp. 202-212
    • Lam, J.S.1    Leppert, J.T.2    Belldegrun, A.S.3    Figlin, R.A.4
  • 3
    • 0344442746 scopus 로고    scopus 로고
    • Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease
    • Janzen NK, Kim HL, Figlin RA, Belldegrun AS. Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease. Urol Clin North Am. 2003;30(4): 843-852.
    • (2003) Urol Clin North Am , vol.30 , Issue.4 , pp. 843-852
    • Janzen, N.K.1    Kim, H.L.2    Figlin, R.A.3    Belldegrun, A.S.4
  • 4
    • 0036138580 scopus 로고    scopus 로고
    • Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
    • Motzer RJ, Bacik J, Murphy BA, Russo P, Mazumdar M. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol. 2002;20(1):289-296.
    • (2002) J Clin Oncol , vol.20 , Issue.1 , pp. 289-296
    • Motzer, R.J.1    Bacik, J.2    Murphy, B.A.3    Russo, P.4    Mazumdar, M.5
  • 6
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • Motzer RJ, Mazumdar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol. 1999;17(8):2530-2540.
    • (1999) J Clin Oncol , vol.17 , Issue.8 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3    Berg, W.4    Amsterdam, A.5    Ferrara, J.6
  • 7
    • 0035818877 scopus 로고    scopus 로고
    • Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for meta-static renal-cell cancer
    • Flanigan RC, Salmon SE, Blumenstein BA, et al. Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for meta-static renal-cell cancer. N Engl J Med. 2001;345(23):1655-1659.
    • (2001) N Engl J Med , vol.345 , Issue.23 , pp. 1655-1659
    • Flanigan, R.C.1    Salmon, S.E.2    Blumenstein, B.A.3
  • 8
    • 0035934596 scopus 로고    scopus 로고
    • Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: A randomised trial
    • Mickisch GH, Garin A, van Poppel H, de Prijck L, Sylvester R. Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: a randomised trial. Lancet. 2001;358(9286):966-970.
    • (2001) Lancet , vol.358 , Issue.9286 , pp. 966-970
    • Mickisch, G.H.1    Garin, A.2    van Poppel, H.3    de Prijck, L.4    Sylvester, R.5
  • 9
    • 14144252047 scopus 로고    scopus 로고
    • Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma
    • Mekhail TM, Abou-Jawde RM, Boumerhi G, et al. Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma. J Clin Oncol. 2005;23(4):832-841.
    • (2005) J Clin Oncol , vol.23 , Issue.4 , pp. 832-841
    • Mekhail, T.M.1    Abou-Jawde, R.M.2    Boumerhi, G.3
  • 10
    • 23744461813 scopus 로고    scopus 로고
    • Prognostic factors of response or failure of treatment in patients with metastatic renal carcinomas treated by cytokines: A report from the Groupe Francais d'Immunotherapie
    • Negrier S, Gomez F, Douillard J Y, et al. Prognostic factors of response or failure of treatment in patients with metastatic renal carcinomas treated by cytokines: a report from the Groupe Francais d'Immunotherapie. World J Urol. 2005;23(3):161-165.
    • (2005) World J Urol , vol.23 , Issue.3 , pp. 161-165
    • Negrier, S.1    Gomez, F.2    Douillard, J.Y.3
  • 11
    • 34547108341 scopus 로고    scopus 로고
    • Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy
    • Choueiri TK, Garcia JA, Elson P, et al. Clinical factors associated with outcome in patients with metastatic clear-cell renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. Cancer. 2007;110(3):543-550.
    • (2007) Cancer , vol.110 , Issue.3 , pp. 543-550
    • Choueiri, T.K.1    Garcia, J.A.2    Elson, P.3
  • 12
    • 73349084973 scopus 로고    scopus 로고
    • Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: Results from a large, multicenter study
    • Heng DY, Xie W, Regan MM, et al. Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol. 2009.
    • (2009) J Clin Oncol
    • Heng, D.Y.1    Xie, W.2    Regan, M.M.3
  • 13
    • 0035868654 scopus 로고    scopus 로고
    • Improved prognostication of renal cell carcinoma using an integrated staging system
    • Zisman A, Pantuck AJ, Dorey F, et al. Improved prognostication of renal cell carcinoma using an integrated staging system. J Clin Oncol. 2001;19(6):1649-1657.
    • (2001) J Clin Oncol , vol.19 , Issue.6 , pp. 1649-1657
    • Zisman, A.1    Pantuck, A.J.2    Dorey, F.3
  • 14
    • 21044433148 scopus 로고    scopus 로고
    • Prognostic value of histologic subtypes in renal cell carcinoma: A multicenter experience
    • Patard JJ, Leray E, Rioux-Leclercq N, et al. Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol. 2005;23(12):2763-2771.
    • (2005) J Clin Oncol , vol.23 , Issue.12 , pp. 2763-2771
    • Patard, J.J.1    Leray, E.2    Rioux-Leclercq, N.3
  • 15
    • 0036893892 scopus 로고    scopus 로고
    • An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: The SSIGN score
    • Frank I, Blute ML, Cheville JC, Lohse CM, Weaver AL, Zincke H. An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: the SSIGN score. J Urol. 2002;168(6):2395-2400.
    • (2002) J Urol , vol.168 , Issue.6 , pp. 2395-2400
    • Frank, I.1    Blute, M.L.2    Cheville, J.C.3    Lohse, C.M.4    Weaver, A.L.5    Zincke, H.6
  • 16
    • 0345098465 scopus 로고    scopus 로고
    • Scoring algorithm to predict survival after nephrectomy and immunotherapy in patients with meta-static renal cell carcinoma: A stratification tool for prospective clinical trials
    • Leibovich BC, Han KR, Bui MH, et al. Scoring algorithm to predict survival after nephrectomy and immunotherapy in patients with meta-static renal cell carcinoma: a stratification tool for prospective clinical trials. Cancer. 2003;98(12):2566-2575.
    • (2003) Cancer , vol.98 , Issue.12 , pp. 2566-2575
    • Leibovich, B.C.1    Han, K.R.2    Bui, M.H.3
  • 17
    • 0029026384 scopus 로고
    • Prognostic factors for survival in patients with metastatic renal cancer treated with biological response modifers
    • Mani S, Todd MB, Katz K, Poo WJ. Prognostic factors for survival in patients with metastatic renal cancer treated with biological response modifers. J Urol. 1995;154(1):35-40.
    • (1995) J Urol , vol.154 , Issue.1 , pp. 35-40
    • Mani, S.1    Todd, M.B.2    Katz, K.3    Poo, W.J.4
  • 18
    • 0035116618 scopus 로고    scopus 로고
    • Sarcomatoid differentiation in renal cell carcinoma: A study of 101 cases
    • de Peralta-Venturina M, Moch H, Amin M, et al. Sarcomatoid differentiation in renal cell carcinoma: a study of 101 cases. Am J Surg Pathol. 2001;25(3):275-284.
    • (2001) Am J Surg Pathol , vol.25 , Issue.3 , pp. 275-284
    • de Peralta-Venturina, M.1    Moch, H.2    Amin, M.3
  • 19
    • 0036719229 scopus 로고    scopus 로고
    • Doxorubicin and ifosfamide in patients with metastatic sarcomatoid renal cell carcinoma: A phase II study of the Genitourinary Group of the French Federation of Cancer Centers
    • Escudier B, Droz J P, Rolland F, et al. Doxorubicin and ifosfamide in patients with metastatic sarcomatoid renal cell carcinoma: a phase II study of the Genitourinary Group of the French Federation of Cancer Centers. J Urol. 2002;168(3):959-961.
    • (2002) J Urol , vol.168 , Issue.3 , pp. 959-961
    • Escudier, B.1    Droz, J.P.2    Rolland, F.3
  • 20
    • 0037407573 scopus 로고    scopus 로고
    • Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma
    • Cheville JC, Lohse CM, Zincke H, Weaver AL, Blute ML. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol. 2003;27(5):612-624.
    • (2003) Am J Surg Pathol , vol.27 , Issue.5 , pp. 612-624
    • Cheville, J.C.1    Lohse, C.M.2    Zincke, H.3    Weaver, A.L.4    Blute, M.L.5
  • 21
    • 20244386849 scopus 로고    scopus 로고
    • Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma
    • Kim HL, Seligson D, Liu X, et al. Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma. J Urol. 2005;173(5):1496-1501.
    • (2005) J Urol , vol.173 , Issue.5 , pp. 1496-1501
    • Kim, H.L.1    Seligson, D.2    Liu, X.3
  • 22
    • 36048987954 scopus 로고    scopus 로고
    • Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma
    • Leibovich BC, Sheinin Y, Lohse CM, et al. Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma. J Clin Oncol. 2007;25(30):4757-4764.
    • (2007) J Clin Oncol , vol.25 , Issue.30 , pp. 4757-4764
    • Leibovich, B.C.1    Sheinin, Y.2    Lohse, C.M.3
  • 23
    • 2442490125 scopus 로고    scopus 로고
    • Prognostic value of carbonic anhydrase IX and KI67 as predictors of survival for renal clear cell carcinoma
    • Bui MH, Visapaa H, Seligson D, et al. Prognostic value of carbonic anhydrase IX and KI67 as predictors of survival for renal clear cell carcinoma. J Urol. 2004;171(6 Pt 1):2461-2466.
    • (2004) J Urol , vol.171 , Issue.1-6 , pp. 2461-2466
    • Bui, M.H.1    Visapaa, H.2    Seligson, D.3
  • 24
    • 0037314709 scopus 로고    scopus 로고
    • Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: Implications for prognosis and therapy
    • Bui MH, Seligson D, Han KR, et al. Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. Clin Cancer Res. 2003;9(2):802-811.
    • (2003) Clin Cancer Res , vol.9 , Issue.2 , pp. 802-811
    • Bui, M.H.1    Seligson, D.2    Han, K.R.3
  • 25
    • 21044442672 scopus 로고    scopus 로고
    • Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer
    • Atkins M, Regan M, McDermott D, et al. Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer. Clin Cancer Res. 2005;11(10):3714-3721.
    • (2005) Clin Cancer Res , vol.11 , Issue.10 , pp. 3714-3721
    • Atkins, M.1    Regan, M.2    McDermott, D.3
  • 26
    • 48649098245 scopus 로고    scopus 로고
    • Von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma
    • discussion 865-866
    • Choueiri TK, Vaziri SA, Jaeger E, et al. Von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma. J Urol. 2008;180(3):860-865; discussion 865-866.
    • (2008) J Urol , vol.180 , Issue.3 , pp. 860-865
    • Choueiri, T.K.1    Vaziri, S.A.2    Jaeger, E.3
  • 27
    • 38949093560 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations in the von hippel-lindau gene: The influence on renal cancer prognosis
    • Smits KM, Schouten LJ, van Dijk BA, et al. Genetic and epigenetic alterations in the von hippel-lindau gene: the influence on renal cancer prognosis. Clin Cancer Res. 2008;14(3):782-787.
    • (2008) Clin Cancer Res , vol.14 , Issue.3 , pp. 782-787
    • Smits, K.M.1    Schouten, L.J.2    van Dijk, B.A.3
  • 28
    • 44949119410 scopus 로고    scopus 로고
    • Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma
    • Patard JJ, Fergelot P, Karakiewicz PI, et al. Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma. Int J Cancer. 2008;123(2):395-400.
    • (2008) Int J Cancer , vol.123 , Issue.2 , pp. 395-400
    • Patard, J.J.1    Fergelot, P.2    Karakiewicz, P.I.3
  • 29
    • 0037304479 scopus 로고    scopus 로고
    • Elevated Akt activation and its impact on clinic pathological features of renal cell carcinoma
    • Horiguchi A, Oya M, Uchida A, Marumo K, Murai M. Elevated Akt activation and its impact on clinic pathological features of renal cell carcinoma. J Urol. 2003;169(2):710-713.
    • (2003) J Urol , vol.169 , Issue.2 , pp. 710-713
    • Horiguchi, A.1    Oya, M.2    Uchida, A.3    Marumo, K.4    Murai, M.5
  • 30
    • 41149145266 scopus 로고    scopus 로고
    • External validation of IMP3 expression as an independent prognostic marker for metastatic progression and death for patients with clear cell renal cell carcinoma
    • Hoffmann NE, Sheinin Y, Lohse CM, et al. External validation of IMP3 expression as an independent prognostic marker for metastatic progression and death for patients with clear cell renal cell carcinoma. Cancer. 2008;112(7):1471-1479.
    • (2008) Cancer , vol.112 , Issue.7 , pp. 1471-1479
    • Hoffmann, N.E.1    Sheinin, Y.2    Lohse, C.M.3
  • 31
    • 77955358134 scopus 로고    scopus 로고
    • Serum soluble B7x is elevated in renal cell carcinoma patients and is associated with advanced stage. 2008
    • abstr
    • Thompson R ZX, Hohse CM, et al. Serum soluble B7x is elevated in renal cell carcinoma patients and is associated with advanced stage. 2008 Genitourinary Cancers Symposium. 2008:abstr 383.
    • (2008) Genitourinary Cancers Symposium , pp. 383
    • Thompson, R.Z.X.1    Hohse, C.M.2
  • 32
    • 77955359989 scopus 로고    scopus 로고
    • Evaluation of soluble B7x as a serum marker in patients with clear cell renal cell carcinoma
    • abstr
    • Thompson RH ZX, Lohse CM, et al. Evaluation of soluble B7x as a serum marker in patients with clear cell renal cell carcinoma. J Clin Oncol, 2008 ASCO Annual Meeting. 2008;(May 20 suppl):abstr 5052.
    • (2008) J Clin Oncol, 2008 ASCO Annual Meeting , vol.20 , pp. 5052
    • Thompson, R.H.Z.X.1    Lohse, C.M.2
  • 33
    • 36448930484 scopus 로고    scopus 로고
    • Medroxyprogesterone, interferon alfa-2a, interleukin 2, or combination of both cytokines in patients with metastatic renal carcinoma of intermediate prognosis: Results of a randomized controlled trial
    • Negrier S, Perol D, Ravaud A, et al. Medroxyprogesterone, interferon alfa-2a, interleukin 2, or combination of both cytokines in patients with metastatic renal carcinoma of intermediate prognosis: results of a randomized controlled trial. Cancer. 2007;110(11):2468-2477.
    • (2007) Cancer , vol.110 , Issue.11 , pp. 2468-2477
    • Negrier, S.1    Perol, D.2    Ravaud, A.3
  • 34
    • 1542398693 scopus 로고    scopus 로고
    • Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapa-mycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • Atkins MB, Hidalgo M, Stadler WM, et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapa-mycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol. 2004;22(5):909-918.
    • (2004) J Clin Oncol , vol.22 , Issue.5 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3
  • 35
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • Hudes G, Carducci M, Tomczak P, et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med. 2007;356(22):2271-2281.
    • (2007) N Engl J Med , vol.356 , Issue.22 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 36
    • 48649107474 scopus 로고    scopus 로고
    • Effcacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
    • Motzer RJ, Escudier B, Oudard S, et al. Effcacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet. 2008;372(9637):449-456.
    • (2008) Lancet , vol.372 , Issue.9637 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3
  • 37
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med. 2007;356(2): 115-124.
    • (2007) N Engl J Med , vol.356 , Issue.2 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 38
    • 37349080670 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
    • Escudier B, Pluzanska A, Koralewski P, et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet. 2007;370(9605): 2103-2111.
    • (2007) Lancet , vol.370 , Issue.9605 , pp. 2103-2111
    • Escudier, B.1    Pluzanska, A.2    Koralewski, P.3
  • 39
    • 56749161699 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with meta-static renal cell carcinoma: CALGB 90206
    • Rini BI, Halabi S, Rosenberg JE, et al. Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with meta-static renal cell carcinoma: CALGB 90206. J Clin Oncol. 2008;26(33): 5422-5428.
    • (2008) J Clin Oncol , vol.26 , Issue.33 , pp. 5422-5428
    • Rini, B.I.1    Halabi, S.2    Rosenberg, J.E.3
  • 40
    • 70349253166 scopus 로고    scopus 로고
    • A randomized, double-blind, phase III study of pazopanib in treatment-naive and cytokine-pretreated patients with advanced renal cell carcinoma (RCC)
    • Sternberg CN, Szczylik C, Lee E, et al. A randomized, double-blind, phase III study of pazopanib in treatment-naive and cytokine-pretreated patients with advanced renal cell carcinoma (RCC). J Clin Oncol. 2009;27(15s):Abstr 5021.
    • (2009) J Clin Oncol , vol.27 , Issue.15 , pp. 5021
    • Sternberg, C.N.1    Szczylik, C.2    Lee, E.3
  • 41
    • 68949145218 scopus 로고    scopus 로고
    • Overall survival and updated results for sunitinib compared with interferon alfa in patients with meta-static renal cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P, et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with meta-static renal cell carcinoma. J Clin Oncol. 2009;27(22):3584-3590.
    • (2009) J Clin Oncol , vol.27 , Issue.22 , pp. 3584-3590
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 42
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • Motzer RJ, Michaelson MD, Redman BG, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol. 2006;24(1):16-24.
    • (2006) J Clin Oncol , vol.24 , Issue.1 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 43
    • 67651201656 scopus 로고    scopus 로고
    • Safety and efficacy of sunitinib for metastatic renalcell carcinoma: An expanded-access trial
    • Gore ME, Szczylik C, Porta C, et al. Safety and efficacy of sunitinib for metastatic renalcell carcinoma: an expanded-access trial. Lancet Oncol. 2009;10(8):757-763.
    • (2009) Lancet Oncol , vol.10 , Issue.8 , pp. 757-763
    • Gore, M.E.1    Szczylik, C.2    Porta, C.3
  • 44
    • 0034046892 scopus 로고    scopus 로고
    • Phase II.trial of weekly intravenous gemcitabine with continuous infusion fuorouracil in patients with metastatic renal cell cancer
    • Rini BI, Vogelzang NJ, Dumas MC, Wade JL 3rd, Taber DA, Stadler WM. Phase II trial of weekly intravenous gemcitabine with continuous infusion fuorouracil in patients with metastatic renal cell cancer. J Clin Oncol. 2000;18(12):2419-2426.
    • (2000) J Clin Oncol , vol.18 , Issue.12 , pp. 2419-2426
    • Rini, B.I.1    Vogelzang, N.J.2    Dumas, M.C.3    Wade, J.L.4    Taber, D.A.5    Stadler, W.M.6
  • 45
    • 4844231761 scopus 로고    scopus 로고
    • Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma
    • Nanus DM, Garino A, Milowsky MI, Larkin M, Dutcher J P. Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma. Cancer. 2004;101(7):1545-1551.
    • (2004) Cancer , vol.101 , Issue.7 , pp. 1545-1551
    • Nanus, D.M.1    Garino, A.2    Milowsky, M.I.3    Larkin, M.4    Dutcher, J.P.5
  • 46
    • 77955371083 scopus 로고    scopus 로고
    • ECOG 8802: Phase II trial of doxorubicin (Dox) and gemcitabine (Gem) in metastatic renal cell carcinoma (RCC) with sarcomatoid features
    • N Haas JM, Pins M, Liu G, et al. ECOG 8802: Phase II trial of doxorubicin (Dox) and gemcitabine (Gem) in metastatic renal cell carcinoma (RCC) with sarcomatoid features. Genitourinary Cancers Symposium; 2009: abstr 285.
    • (2009) Genitourinary Cancers Symposium , pp. 285
    • Haas, J.M.N.1    Pins, M.2    Liu, G.3
  • 47
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med. 2007;357(26):2666-2676.
    • (2007) N Engl J Med , vol.357 , Issue.26 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3
  • 48
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350(23):2335-2342.
    • (2004) N Engl J Med , vol.350 , Issue.23 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 49
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio BJ, Catalano PJ, Meropol NJ, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol. 2007;25(12):1539-1544.
    • (2007) J Clin Oncol , vol.25 , Issue.12 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3
  • 50
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006;355(24):2542-2550.
    • (2006) N Engl J Med , vol.355 , Issue.24 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 51
    • 62449124416 scopus 로고    scopus 로고
    • Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
    • Reck M, von Pawel J, Zatloukal P, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol. 2009;27(8):1227-1234.
    • (2009) J Clin Oncol , vol.27 , Issue.8 , pp. 1227-1234
    • Reck, M.1    von Pawel, J.2    Zatloukal, P.3
  • 52
    • 59949083263 scopus 로고    scopus 로고
    • Phase II trial of single agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
    • Kreisl TN, Kim L, Moore K, et al. Phase II trial of single agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol. 2009;27(5):740-745.
    • (2009) J Clin Oncol , vol.27 , Issue.5 , pp. 740-745
    • Kreisl, T.N.1    Kim, L.2    Moore, K.3
  • 53
    • 58249124806 scopus 로고    scopus 로고
    • A phase I study of sunitinib in combination with gemcitabine in advanced renal cell carcinoma and other solid tumors
    • Michaelson AS, Ryan D, McDermott D, et al. A phase I study of sunitinib in combination with gemcitabine in advanced renal cell carcinoma and other solid tumors. Genitourinary Cancers Symposium 2008; abstr 362.
    • (2008) Genitourinary Cancers Symposium , pp. 362
    • Michaelson, A.S.1    Ryan, D.2    McDermott, D.3
  • 54
    • 0037093972 scopus 로고    scopus 로고
    • Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma
    • Schouten LJ, Rutten J, Huveneers HA, Twijnstra A. Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer. 2002;94(10):2698-2705.
    • (2002) Cancer , vol.94 , Issue.10 , pp. 2698-2705
    • Schouten, L.J.1    Rutten, J.2    Huveneers, H.A.3    Twijnstra, A.4
  • 55
    • 33748293111 scopus 로고    scopus 로고
    • SU14813: A novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity
    • Patyna S, Laird AD, Mendel DB, et al. SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity. Mol Cancer Ther. 2006;5(7):1774-1782.
    • (2006) Mol Cancer Ther , vol.5 , Issue.7 , pp. 1774-1782
    • Patyna, S.1    Laird, A.D.2    Mendel, D.B.3
  • 56
    • 42049092841 scopus 로고    scopus 로고
    • Sorafenib for metastatic renal cancer: The Princess Margaret experience
    • Riechelmann R P, Chin S, Wang L, et al. Sorafenib for metastatic renal cancer: the Princess Margaret experience. Am J Clin Oncol. 2008;31(2):182-187.
    • (2008) Am J Clin Oncol , vol.31 , Issue.2 , pp. 182-187
    • Riechelmann, R.P.1    Chin, S.2    Wang, L.3
  • 57
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier B, Eisen T, Stadler WM, et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med. 2007;356(2):125-134.
    • (2007) N Engl J Med , vol.356 , Issue.2 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 58
    • 34648863567 scopus 로고    scopus 로고
    • The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial in North America: Safety and effcacy
    • 18S June 20 Supplement
    • JJ Knox RAF, Stadler WM, McDermott DF, et al. The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial in North America: Safety and effcacy. J Clin Oncol, 2007 ASCO Annual Meeting Proceedings. 2007;25(18S (June 20 Supplement)).
    • (2007) J Clin Oncol, 2007 ASCO Annual Meeting Proceedings , vol.25
    • Knox, R.A.F.J.J.1    Stadler, W.M.2    McDermott, D.F.3
  • 59
    • 65949102290 scopus 로고    scopus 로고
    • Prognostic factors for survival in metastatic renal cell carcinoma: Update 2008
    • Bukowski RM. Prognostic factors for survival in metastatic renal cell carcinoma: update 2008. Cancer. 2009;115(10 Suppl):2273-2281.
    • (2009) Cancer , vol.115 , Issue.10 SUPPL. , pp. 2273-2281
    • Bukowski, R.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.