Synthesis of optically pure lactone metabolites of tea catechins

Synthesis

Volumn , Issue 9, 2010, Pages 1512-1520

  Hamada, Masahiro ^a   Furuno, Ai ^a   Nakano, Sousuke ^a   Kishimoto, Takao ^a   Nakajima, Noriyuki ^a  

^a TOYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Cyclizations; Lactones; Polyphenols; Stereoselective synthesis; Tea catechins

Indexed keywords

BIOLOGICAL ACTIVITIES; CYCLIZATIONS; HUMAN BODIES; METABOLIC PATHWAYS; POLYPHENOLS; STEREOSELECTIVE SYNTHESIS; TEA CATECHIN;

BIOMOLECULES; COMPLEXATION; CYCLIZATION; METABOLISM; METABOLITES; STEREOSELECTIVITY;

PHENOLS;

1 [3 [TERT BUTYL(DIMETHYL)SILOXY]BENZYL] 2 HYDROXYETHYL ACETATE; 1 [3,4 BIS[TERT BUTYL(DIMETHYL)SILOXY]BENZYL] 2 HYDROXYETHYL ACETATE; 1 [3,5 BIS[TERT BUTYL(DIMETHYL)SILOXY]BENZYL] 2 HYDROXYETHYL ACETATE; 1 BENZYLOXY 1 [3 [TERT BUTYL(DIMETHYL)SILOXY]BENZYL]ETHYL ACETATE; 2 (BENZYLOXY) 1 [3,4 BIS[TERT BUTYL(DIMETHYL)SILOXY]BENZYL]ETHYL ACETATE; 2 (BENZYLOXY) 1 [3,4,5 TRIS[TERT BUTYL(DIMETHYL)SILOXY]BENZYL]ETHYL ACETATE; 2 (BENZYLOXY) 1 [3,5 BIS[TERT BUTYL(DIMETHYL)SILOXY]BENZYL]ETHYL ACETATE; 2 HYDROXY 1 [3,4,5 TRIS[TERT BUTYL(DIMETHYL)SILOXY]BENZYL]ETHYL ACETATE; 5 (3 HYDROXYPHENYL)DIHYDROFURAN 2(3H)ONE; 5 (3,4 DIHYDROXYBENZYL)DIHYDROFURAN 2(3H)ONE; 5 (3,4 DIHYDROXYPHENYL)GAMMA VALEROLACTONE; 5 (3,4,5 TRIHYDROXYPHENYL)DIHYDROFURAN 2(3H)ONE; 5 (3,5 DIHYDROXYPHENYL)DIHYDROFURAN 2(3H)ONE; CATECHOL DERIVATIVE; DRUG METABOLITE; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; ETHYL 4 (ACETOXY) 5 [3 [TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL]PENT 2 ENOATE; ETHYL 4 (ACETOXY) 5 [3,4 BIS[TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL]PENT 2 ENOATE; ETHYL 4 (ACETOXY) 5 [3,4,5 TRIS[TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL]PENT 2 ENOATE; ETHYL 4 (ACETOXY) 5 [3,5 BIS[TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL]PENT 2 ENOATE; ETHYL 4 HYDROXY 5 [3,4,5 TRIS[TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL]PENT 2 ENOATE; ETHYL 5 [3 [TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL] 4 HYDROXYPENT 2 ENOATE; ETHYL 5 [3,4 BIS[TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL] 4 HYDROXYPENT 2 ENOATE; ETHYL 5 [3,4 BIS[TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL] 4 HYDROXYPENTANOATE; ETHYL 5 [3,5 BIS[TERT BUTYL(DIMETHYL)SILYLOXY]PHENYL] 4 HYDROXYPENT 2 ENOATE; LACTONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CYCLIZATION; DRUG PURITY; DRUG STRUCTURE; DRUG SYNTHESIS; LACTONIZATION; NONHUMAN; STEREOCHEMISTRY; TEA;

EID: 77955402178     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1218671     Document Type: Article

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