Current aspects of the pathology and differentiation of extranodal marginal zone B-cell lymphoma, MALT-type, and gastrointestinal diffuse large B-cell lymphoma;Aktuelle molekular-zytogenetische aspekte zur pathologie und differenzierung von extranodalen marginalzonen B-zell-lymphomen vom MALT-typ und gastrointestinalen diffusen großzelligen B-zell-lymphomen

Zeitschrift fur Gastroenterologie

Volumn 48, Issue 8, 2010, Pages 833-838

  Flossbach L ^a   Kestler, H A ^a,b   Gress, T M ^a,c   Moller P ^a   Barth, T F E ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

gastric DLBCL; MALT lymphom; molecular biology

Indexed keywords

B CELL LYMPHOMA; CAMPYLOBACTER JEJUNI; CANCER GROWTH; CARCINOGENESIS; DISEASE ASSOCIATION; GASTROINTESTINAL TRACT; HELICOBACTER PYLORI; HUMAN; LARGE CELL LYMPHOMA; MARGINAL ZONE LYMPHOMA; REVIEW; TUMOR LOCALIZATION;

DIAGNOSIS, DIFFERENTIAL; HUMANS; LYMPHOMA, B-CELL; LYMPHOMA, B-CELL, MARGINAL ZONE; NEOPLASM PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 77955393511     PISSN: 00442771     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0029-1245421     Document Type: Review

References (56)

1. dAmore F, Christensen B E., Brincker H et al. Clinicopathological features and prognostic factors in extranodal non-Hodgkin lymphomas. Danish LYFO Study Group. Eur J Cancer 1991 27 1201-1208
2. Zheng T, Mayne S T., Boyle P et al. Epidemiology of non-Hodgkin lymphoma in Connecticut. 1935 1988. Cancer 1992 70 840-849
3. A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkins lymphoma. The Non-Hodgkins Lymphoma Classification Project. Blood 1997 89 3909-3918
4. Newton R, Ferlay J, Beral V et al. The epidemiology of non-Hodgkins lymphoma: comparison of nodal and extra-nodal sites. Int J Cancer 1997 72 923-930
5. Hussell T, Isaacson P G., Crabtree J E. et al. The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori. Lancet 1993 342 571-574
6. Greiner A, Marx A, Heesemann J et al. Idiotype identity in a MALT-type lymphoma and B cells in Helicobacter pylori associated chronic gastritis. Lab Invest 1994 70 572-578
7. Isaacson P G., Du M Q. MALT lymphoma: from morphology to molecules. Nat Rev Cancer 2004 4 644-653
8. Isaacson P G., Chott A, Nakamura S et al. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). World Health Organization Classification of Tumours of Hematopoietic and Lymphoid Tisues. Swerdlow SH Campo E Harris NL et al. 2008 214-217
9. Wotherspoon A C., Ortiz-Hidalgo C, Falzon M R. et al. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 1991 338 1175-1176
10. Karat D, OHanlon D M., Hayes N et al. Prospective study of Helicobacter pylori infection in primary gastric lymphoma. Br J Surg 1995 82 1369-1370
11. Bouzourene H, Haefliger T, Delacretaz F et al. The role of Helicobacter pylori in primary gastric MALT lymphoma. Histopathology 1999 34 118-123
12. Lecuit M, Abachin E, Martin A et al. Immunoproliferative small intestinal disease associated with Campylobacter jejuni. N Engl J Med 2004 350 239-248 (Pubitemid 38067636)
13. Wundisch T, Mosch C, Neubauer A et al. Helicobacter pylori eradication in gastric mucosa-associated lymphoid tissue lymphoma: Results of a 196-patient series. Leuk Lymphoma 2006 47 2110-2114
14. Bayerdorffer E, Neubauer A, Rudolph B et al. Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of Helicobacter pylori infection. MALT Lymphoma Study Group. Lancet 1995 345 1591-1594
15. Du M Q., Isaccson P G. Gastric MALT lymphoma: from aetiology to treatment. Lancet Oncol 2002 3 97-104
16. Fischbach W, Malfertheiner P, Hoffmann J C. et al. S3-guideline helicobacter pylori and gastroduodenal ulcer disease of the German society for digestive and metabolic diseases (DGVS) in cooperation with the German society for hygiene and microbiology, society for pediatric gastroenterology and nutrition e. V., German society for rheumatology, AWMF-registration-no. 021 / 001. Z Gastroenterol 2009 47 1230-1263
17. Koch P, Probst A, Berdel W E. et al. Treatment results in localized primary gastric lymphoma: data of patients registered within the German multicenter study (GIT NHL 02 / 96). JClin Oncol 2005 23 7050-7059
18. Hussell T, Isaacson P G., Crabtree J E. et al. Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue. JPathol 1996 178 122-127
19. Nakamura S, Aoyagi K, Furuse M et al. B-cell monoclonality precedes the development of gastric MALT lymphoma in Helicobacter pylori-associated chronic gastritis. Am J Pathol 1998 152 1271-1279
20. Ott G, Katzenberger T, Greiner A et al. The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkins lymphomas of the mucosa-associated lymphoid tissue (MALT-) type. Cancer Res 1997 57 3944-3948
21. Auer I A., Gascoyne R D., Connors J M. et al. t(11;18)(q21;q21) is the most common translocation in MALT lymphomas. Ann Oncol 1997 8 979-985
22. Remstein E D., James C D., Kurtin P J. Incidence and subtype specificity of API2-MALT1 fusion translocations in extranodal, nodal, and splenic marginal zone lymphomas. Am J Pathol 2000 156 1183-1188
23. Ye H, Liu H, Attygalle A et al. Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma. Blood 2003 102 1012-1018
24. Remstein E D., Kurtin P J., James C D. et al. Mucosa-associated lymphoid tissue lymphomas with t(11;18)(q21;q21) and mucosa-associated lymphoid tissue lymphomas with aneuploidy develop along different pathogenetic pathways. Am J Pathol 2002 161 63-71
25. Uren A G., ORourke K, Aravind L A. et al. Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol Cell 2000 6 961-967
26. Lucas P C., Yonezumi M, Inohara N et al. Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. J Biol Chem 2001 276 19 012-19 019
27. Liu H, Ye H, Ruskone-Fourmestraux A et al. T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication. Gastroenterology 2002 122 1286-1294
28. Liu H, Ye H, Dogan A et al. T(11;18)(q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10. Blood 2001 98 1182-1187
29. Streubel B, Simonitsch-Klupp I, Mullauer L et al. Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites. Leukemia 2004 18 1722-1726
30. Du M, Peng H, Singh N et al. The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma. Blood 1995 86 4587-4593
31. Neumeister P, Hoefler G, Beham-Schmid C et al. Deletion analysis of the p16 tumor suppressor gene in gastrointestinal mucosa-associated lymphoid tissue lymphomas. Gastroenterology 1997 112 1871-1875
32. Barth T F., Bentz M, Leithauser F et al. Molecular-cytogenetic comparison of mucosa-associated marginal zone B-cell lymphoma and large B-cell lymphoma arising in the gastro-intestinal tract. Genes Chromosomes. Cancer 2001 31 316-325
33. Zhou Y, Ye H, Martin-Subero J I. et al. Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21). Br J Haematol 2006 133 35-42
34. Barth T F., Bentz M, Leithauser F et al. Pathogenic complexity of gastric B-cell lymphoma. Blood 2002 100 1095-1096
35. Cabras A D., Candidus S, Fend F et al. Biclonality of gastric lymphomas. Lab Invest 2001 81 961-967
36. Barth T F., Dohner H, Werner C A. et al. Characteristic pattern of chromosomal gains and losses in primary large B-cell lymphomas of the gastrointestinal tract. Blood 1998 91 4321-4330
37. Streubel B, Lamprecht A, Dierlamm J et al. T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma. Blood 2003 101 2335-2339
38. Ye H, Gong L, Liu H et al. MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression. J Pathol 2005 205 293-301
39. Sanchez-Izquierdo D, Buchonnet G, Siebert R et al. MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma. Blood 2003 101 4539-4546
40. Dierlamm J, Murga Penas E M., Bentink S et al. Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. Haematologica 2008 93 688-696
41. Willis T G., Jadayel D M., Du M Q. et al. Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. Cell 1999 96 35-45
42. Zhang Q, Siebert R, Yan M et al. Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). Nat Genet 1999 22 63-68
43. Ye H, Gong L, Liu H et al. Strong BCL10 nuclear expression identifies gastric MALT lymphomas that do not respond to H pylori eradication. Gut 2006 55 137-138
44. Thome MCARMA1, BCL-10 and MALT1 in lymphocyte development and activation. Nat Rev Immunol 2004 4 348-359
45. Dong G, Liu C, Ye H et al. BCL10 nuclear expression and t(11;18)(q21;q21) indicate nonresponsiveness to Helicobacter pylori eradication of Chinese primary gastric MALT lymphoma. Int J Hematol 2008 88 516-523
46. Ohshima K, Kawasaki C, Muta H et al. CD10 and Bcl10 expression in diffuse large B-cell lymphoma: CD 10 is a marker of improved prognosis. Histopathology 2001 39 156-162
47. Streubel B, Vinatzer U, Lamprecht A et al. T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphoma. Leukemia 2005 19 652-658
48. Wlodarska I, Veyt E, Paepe P de et al. FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations. Leukemia 2005 19 1299-1305
49. Fenton J A., Schuuring E, Barrans S L. et al. t(3;14)(p14;q32) results in aberrant expression of FOXP1 in a case of diffuse large B-cell lymphoma. Genes Chromosomes. Cancer 2006 45 164-168
50. Ye H, Remstein E D., Bacon C M. et al. Chromosomal translocations involving BCL6 in MALT lymphoma. Haematologica 2008 93 145-146
51. Chen Y W., Hu X T., Liang A C. et al. High BCL6 expression predicts better prognosis, independent of BCL6 translocation status, translocation partner, or BCL6-deregulating mutations, in gastric lymphoma. Blood 2006 108 2373-2383
52. Remstein E D., Dogan A, Einerson R R. et al. The incidence and anatomic site specificity of chromosomal translocations in primary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in North America. Am J Surg Pathol 2006 30 1546-1553
53. Nakamura S, Ye H, Bacon C M. et al. Clinical impact of genetic aberrations in gastric MALT lymphoma: a comprehensive analysis using interphase fluorescence in situ hybridisation. Gut 2007 56 1358-1363
54. Vinatzer U, Gollinger M, Mullauer L et al. Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3. Clin Cancer Res 2008 14 6426-6431
55. Nakamura S, Ye H, Bacon C M. et al. Translocations involving the immunoglobulin heavy chain gene locus predict better survival in gastric diffuse large B-cell lymphoma. Clin Cancer Res 2008 14 3002-3010
56. Barth T F., Barth C A., Kestler H A. et al. Transcriptional profiling suggests that secondary and primary large B-cell lymphomas of the gastrointestinal (GI) tract are blastic variants of GI marginal zone lymphoma. J Pathol 2007 211 305-313