Strong BCL10 nuclear expression identifies gastric MALT lymphomas that do not respond to H pylori eradication [9]

Gut

Volumn 55, Issue 1, 2006, Pages 137-139

  Ye, H ^a   Gong, L ^a   Liu, H ^a   Ruskone Fourmestraux, A ^b,c   De Jong, D ^d   Pileri, S ^e   Thiede, C ^f   Lavergne, A ^c,g   Boot, H ^d   Caletti, G ^h   Wundisch T ⁱ   Molina, T ^b,c   Taal, B G ^d   Elena, S ^e   Neubauer, A ⁱ   MacLennan, K A ^j   Siebert, R ^k   Remstein, E D ^l   Dogan, A ^l   Du, M Q ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HÔPITAL SAINT ANTOINE   (France)

^c GELD (Groupe d'Etude des Lymphomes Digestifs)   (France)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

^e UNIVERSITY OF BOLOGNA   (Italy)

^f UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^g HÔPITAL LARIBOISIÈRE   (France)

^h Servizio di Gastroenterologia   (Italy)

ⁱ PHILIPPS UNIVERSITY MARBURG   (Germany)

^j UNIVERSITY OF LEEDS   (United Kingdom)

^k UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^l MAYO CLINIC   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 10;

CHROMOSOME TRANSLOCATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; HELICOBACTER PYLORI; HUMAN; LETTER; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH MUCOSA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 14; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; LYMPHOMA, MUCOSA-ASSOCIATED LYMPHOID TISSUE; MALE; MIDDLE AGED; NEOPLASM PROTEINS; STOMACH NEOPLASMS; TRANSLOCATION, GENETIC;

EID: 29244466498     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2005.081117     Document Type: Letter

References (9)

1. Isaacson PG, Du MQ. MALT lymphoma: from morphology to molecules. Nat Rev Cancer 2004;4:644-53.
2. Sackmann M, Morgner A, Rudolph B, et al. Regression of gastric MALT lymphoma after eradication of Helicobacter pylori is predicted by endosonographic staging. MALT Lymphoma Study Group. Gastroenterology 1997;113:1087-90.
3. Nakamura S, Matsumoto T, Suekane H, et al. Predictive value of endoscopic ultrasonoaraphy for regression of gastric low grade and high grade MALT lympnomas after eradication of Helicobacter pylori. Gut 2001;48:454-60.
4. Ruskone-Fourmestraux A, Lavergne A, Aegerter PH, et al. Predictive factors for regression of gastric MALT lymphoma after anti-Helicobacter pylori treatment. Gut 2001;48:297-303.
5. Liu H, Ye H, Ruskone-Fourmestraux A, et al. T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication. Gastroenterology 2002;122:1286-94.
6. Ye H, Gong L, Liu H, et al. MALT lymphoma with t(14;18)(q32;q21)/IGH- MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression. J Pathol 2005;205:293-301.
7. Ye H, Liu H, Attygalle A, et al. Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma. Blood 2003;102:1012-18.
8. Willis TG, Jadayel DM, Du MQ, et al. Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. Cell 1999;96:35-45.
9. Zhang Q, Siebert R, Yan M, et al. Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). Nat Genet 1999;22:63-8.