Adenosine A2 receptors modulate tubuloglomerular feedback

American Journal of Physiology - Renal Physiology

Volumn 299, Issue 2, 2010, Pages

  Carlström, Mattias ^a   Wilcox, Christopher S ^a   Welch, William J ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adenosine receptors; Kidney; Micropuncture; Renal microcirculation

Indexed keywords

1 BUTYL 8 [HEXAHYDRO 2,5 METHANOPENTALEN 3A(1H) YL] 3,7 DIHYDRO 3 (3 HYDROXYPROPYL) 1H PURINE 2,6 DIONE; 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR; PSB 36; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTERIOLE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; FEEDBACK SYSTEM; GLOMERULUS; HENLE LOOP; INHIBITION KINETICS; KIDNEY CIRCULATION; KIDNEY PERFUSION; KIDNEY TUBULE; MALE; MICROCIRCULATION; NONHUMAN; PRESSURE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM;

EID: 77955389707     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00211.2010     Document Type: Article

References (35)

1. Abo-Salem OM, Hayallah AM, Bilkei-Gorzo A, Filipek B, Zimmer A, Muller CE. Antinociceptive effects of novel A2B adenosine receptor antagonists. J Pharmacol Exp Ther 308: 358-366, 2004.
2. Al-Mashhadi RH, Skott O, Vanhoutte PM, Hansen PB. Activation of A(2) adenosine receptors dilates cortical efferent arterioles in mouse. Kidney Int 75: 793-799, 2009.
3. Bilkei-Gorzo A, Abo-Salem OM, Hayallah AM, Michel K, Muller CE, Zimmer A. Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia. Naunyn Schmiedebergs Arch Pharmacol 377: 65-76, 2008.
4. Brown R, Ollerstam A, Johansson B, Skott O, Gebre-Medhin S, Fredholm B, Persson AE. Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice. Am J Physiol Regul Integr Comp Physiol 281: R1362-R1367, 2001.
5. Carlstrom M, Lai EY, Ma Z, Patzak A, Brown RD, Persson AE. Role of NOX2 in the regulation of afferent arteriole responsiveness. Am J Physiol Regul Integr Comp Physiol 296: R72-R79, 2009.
6. Chan CM, Unwin RJ, Bardini M, Oglesby IB, Ford AP, Townsend-Nicholson A, Burnstock G. Localization of P2X1 purinoceptors by autoradiography and immunohistochemistry in rat kidneys. Am J Physiol Renal Physiol 274: F799-F804, 1998. (Pubitemid 128734795)
7. Feng MG, Navar LG. Adenosine A2 receptor activation attenuates afferent arteriolar autoregulation during adenosine receptor saturation in rats. Hypertension 50: 744-749, 2007.
8. Franco M, Bell PD, Navar LG. Effect of adenosine A1 analog on tubuloglomerular feedback mechanism. Am J Physiol Renal Fluid Electrolyte Physiol 257: F231-F236, 1989.
9. Golembiowska K, Dziubina A, Kowalska M, Kaminska K. Effect of adenosine A(2A) receptor antagonists on L-DOPA-induced hydroxyl radical formation in rat striatum. Neurotox Res 15: 155-166, 2009.
10. Hansen PB, Hashimoto S, Oppermann M, Huang Y, Briggs JP, Schnermann J. Vasoconstrictor and vasodilator effects of adenosine in the mouse kidney due to preferential activation of A1 or A2 adenosine receptors. J Pharmacol Exp Ther 315: 1150-1157, 2005.
11. Inscho EW. ATP, P2 receptors and the renal microcirculation. Purinergic Signal 5: 447-460, 2009.
12. Inscho EW, Cook AK, Imig JD, Vial C, Evans RJ. Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior. J Clin Invest 112: 1895-1905, 2003.
13. Jackson EK, Zhu C, Tofovic SP. Expression of adenosine receptors in the preglomerular microcirculation. Am J Physiol Renal Physiol 283: F41-F51, 2002. (Pubitemid 34680470)
14. Kawabata M, Ogawa T, Takabatake T. Control of rat glomerular microcirculation by juxtaglomerular adenosine A1 receptors. Kidney Int Suppl 67: S228-S230, 1998.
15. Keddie JR, Poucher SM, Shaw GR, Brooks R, Collis MG. In vivo characterisation of ZM 241385, a selective adenosine A2A receptor antagonist. Eur J Pharmacol 301: 107-113, 1996.
16. Klotz KN. Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch Pharmacol 362: 382-391, 2000.
17. Lai EY, Patzak A, Steege A, Mrowka R, Brown R, Spielmann N, Persson PB, Fredholm BB, Persson AE. Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction. Kidney Int 70: 690-698, 2006.
18. Lasley RD, Kristo G, Keith BJ, Mentzer RM Jr. The A2A/A2B receptor antagonist ZM-241385 blocks the cardioprotective effect of adenosine agonist pretreatment in in vivo rat myocardium. Am J Physiol Heart Circ Physiol 292: H426-H431, 2007.
19. Li JM, Fenton RA, Cutler BS, Dobson JG Jr. Adenosine enhances nitric oxide production by vascular endothelial cells. Am J Physiol Cell Physiol 269: C519-C523, 1995.
20. Osswald H, Hermes HH, Nabakowski G. Role of adenosine in signal transmission of tubuloglomerular feedback. Kidney Int Suppl 12: S136-S142, 1982.
21. Poucher SM, Keddie JR, Brooks R, Shaw GR, McKillop D. Pharmacodynamics of ZM 241385, a potent A2a adenosine receptor antagonist, after enteric administration in rat, cat and dog. J Pharm Pharmacol 48: 601-606, 1996. (Pubitemid 26254697)
22. Ray CJ, Marshall JM. The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium. J Physiol 570: 85-96, 2006.
23. Ren Y, Arima S, Carretero OA, Ito S. Possible role of adenosine in macula densa control of glomerular hemodynamics. Kidney Int 61: 169-176, 2002.
24. Ren Y, Garvin JL, Carretero OA. Efferent arteriole tubuloglomerular feedback in the renal nephron. Kidney Int 59: 222-229, 2001.
25. Ren Y, Garvin JL, Liu R, Carretero OA. Role of macula densa adenosine triphosphate (ATP) in tubuloglomerular feedback. Kidney Int 66: 1479-1485, 2004.
26. Schnermann J. Effect of adenosine analogs on tubuloglomerular feedback responses. Am J Physiol Renal Fluid Electrolyte Physiol 255: F33-F42, 1988.
27. Schnermann J, Briggs JP. Tubuloglomerular feedback: mechanistic insights from gene-manipulated mice. Kidney Int 74: 418-426, 2008.
28. Schnermann J, Persson AE, Agerup B. Tubuloglomerular feedback. Nonlinear relation between glomerular hydrostatic pressure and loop of henle perfusion rate. J Clin Invest 52: 862-869, 1973.
29. Schnermann J, Weihprecht H, Briggs JP. Inhibition of tubuloglomerular feedback during adenosine1 receptor blockade. Am J Physiol Renal Fluid Electrolyte Physiol 258: F553-F561, 1990. (Pubitemid 20103121)
30. Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, Schnermann J. Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci USA 98: 9983-9988, 2001.
31. Teng B, Ledent C, Mustafa SJ. Up-regulation of A 2B adenosine receptor in A 2A adenosine receptor knockout mouse coronary artery. J Mol Cell Cardiol 44: 905-914, 2008.
32. Thorup C, Persson AE. Inhibition of locally produced nitric oxide resets tubuloglomerular feedback mechanism. Am J Physiol Renal Fluid Electrolyte Physiol 267: F606-F611, 1994.
33. Vallon V, Muhlbauer B, Osswald H. Adenosine and kidney function. Physiol Rev 86: 901-940, 2006.
34. Vitzthum H, Weiss B, Bachleitner W, Kramer BK, Kurtz A. Gene expression of adenosine receptors along the nephron. Kidney Int 65: 1180-1190, 2004. (Pubitemid 38406956)
35. Welch WJ, Tojo A, Wilcox CS. Roles of NO and oxygen radicals in tubuloglomerular feedback in SHR. Am J Physiol Renal Physiol 278: F769-F776, 2000.