In vivo characterisation of ZM 241385, a selective adenosine A2A receptor antagonist

European Journal of Pharmacology

Volumn 301, Issue 1-3, 1996, Pages 107-113

  Keddie, John R ^a   Poucher, Simon M ^a   Shaw, Graham R ^a   Brooks, Robert ^a   Collis, Michael G ^a,b  

^a ASTRAZENECA   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Adenosine; Adenosine A2A receptor; Pharmacology, in vivo; ZM 241385

Indexed keywords

4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 6N 2 (4 AMINO 3 IODOPHENYL)ETHYLADENOSINE; 6N CYCLOHEXYL 1,3 DIPROPYLXANTHINE; 8 PHENYLTHEOPHYLLINE; ADENOSINE; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE A3 RECEPTOR AGONIST; ANGIOTENSIN; N [2 (DIMETHYLAMINO)ETHYL] N METHYL 4 (1,3 DIPROPYLXANTHIN 8 YL)BENZENESULFONAMIDE; NITROBENZYLTHIOINOSINE; THEOPHYLLINE; UNCLASSIFIED DRUG; XAMOTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYCARDIA; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; DOG; DRUG ANTAGONISM; DRUG POTENCY; DRUG SELECTIVITY; FEMALE; HINDLIMB; INTRAVENOUS DRUG ADMINISTRATION; LIMB BLOOD FLOW; MEAN ARTERIAL PRESSURE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; VASODILATATION;

ADENOSINE; ANIMALS; CARDIOVASCULAR AGENTS; DECEREBRATE STATE; DOGS; FEMALE; HEART RATE; HINDLIMB; MYOCARDIAL CONTRACTION; RATS; RATS, INBRED SHR; RECEPTORS, PURINERGIC P1; REGIONAL BLOOD FLOW; TRIAZINES; TRIAZOLES; VASODILATION;

EID: 0030001352     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00020-9     Document Type: Article

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