Identification of host proteins associated with HIV-1 preintegration complexes isolated from infected CD4+ cells

Retrovirology

Volumn 7, Issue , 2010, Pages

  Raghavendra, Nidhanapati K ^a   Shkriabai, Nikolozi ^b   Graham, Robert L J ^c   Hess, Sonja ^c   Kvaratskhelia, Mamuka ^b   Wu, Li ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPROTEIN; PREINTEGRATION COMPLEX; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN; PROTEIN;

ARTICLE; CATALYSIS; CD4+ T LYMPHOCYTE; CHROMATIN ASSEMBLY AND DISASSEMBLY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPRECIPITATION; IN VITRO STUDY; MASS SPECTROMETRY; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTEIN TRANSPORT; TWO HYBRID SYSTEM; VIRUS DNA CELL DNA INTERACTION; VIRUS REPLICATION; HOST PATHOGEN INTERACTION; ISOLATION AND PURIFICATION; MACROMOLECULE; METHODOLOGY; PATHOGENICITY; PROTEIN BINDING; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CD4-POSITIVE T-LYMPHOCYTES; DNA, VIRAL; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; MACROMOLECULAR SUBSTANCES; MASS SPECTROMETRY; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEINS; VIROLOGY; VIRUS INTEGRATION;

EID: 77955387972     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-7-66     Document Type: Article

References (31)

1. Poeschla EM. Integrase, LEDGF/p75 and HIV replication. Cell Mol Life Sci 2008, 65:1403-1424. 10.1007/s00018-008-7540-5, 18264802.
2. Grandgenett DP, Bera S, Pandey KK, Vora AC, Zahm J, Sinha S. Biochemical and biophysical analyses of concerted (U5/U3) integration. Methods 2009, 47:229-236. 10.1016/j.ymeth.2008.11.002, 2693883, 19049878.
3. Lin CW, Engelman A. The barrier-to-autointegration factor is a component of functional human immunodeficiency virus type 1 preintegration complexes. J Virol 2003, 77:5030-5036. 10.1128/JVI.77.8.5030-5036.2003, 152146, 12663813.
4. Skalka AM, Katz RA. Retroviral DNA integration and the DNA damage response. Cell Death Differ 2005, 12(Suppl 1):971-978. 10.1038/sj.cdd.4401573, 15761474.
5. Engelman A, Oztop I, Vandegraaff N, Raghavendra NK. Quantitative analysis of HIV-1 preintegration complexes. Methods 2009, 47:283-290. 10.1016/j.ymeth.2009.02.005, 2673482, 19233280.
6. Belshan M, Schweitzer CJ, Donnellan MR, Lu R, Engelman A. In vivo biotinylation and capture of HIV-1 matrix and integrase proteins. J Virol Methods 2009, 159:178-184. 10.1016/j.jviromet.2009.03.017, 2691866, 19490971.
7. Popovic M, Sarngadharan MG, Read E, Gallo RC. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 1984, 224:497-500. 10.1126/science.6200935, 6200935.
8. Farnet CM, Bushman FD. HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro. Cell 1997, 88:483-492. 10.1016/S0092-8674(00)81888-7, 9038339.
9. Zhou Z, Licklider LJ, Gygi SP, Reed R. Comprehensive proteomic analysis of the human spliceosome. Nature 2002, 419:182-185. 10.1038/nature01031, 12226669.
10. Leblond-Francillard M, Dreyfus M, Rougeon F. Isolation of DNA-protein complexes based on streptavidin and biotin interaction. Eur J Biochem 1987, 166:351-355. 10.1111/j.1432-1033.1987.tb13522.x, 3301341.
11. Chen H, Engelman A. The barrier-to-autointegration protein is a host factor for HIV type 1 integration. Proc Natl Acad Sci USA 1998, 95:15270-15274. 10.1073/pnas.95.26.15270, 28032, 9860958.
12. Lee MS, Craigie R. A previously unidentified host protein protects retroviral DNA from autointegration. Proc Natl Acad Sci USA 1998, 95:1528-1533. 10.1073/pnas.95.4.1528, 19075, 9465049.
13. Ao Z, Huang G, Yao H, Xu Z, Labine M, Cochrane AW, Yao X. Interaction of human immunodeficiency virus type 1 integrase with cellular nuclear import receptor importin 7 and its impact on viral replication. J Biol Chem 2007, 282:13456-13467. 10.1074/jbc.M610546200, 17360709.
14. Hamamoto S, Nishitsuji H, Amagasa T, Kannagi M, Masuda T. Identification of a novel human immunodeficiency virus type 1 integrase interactor, Gemin2, that facilitates efficient viral cDNA synthesis in vivo. J Virol 2006, 80:5670-5677. 10.1128/JVI.02471-05, 1472599, 16731905.
15. Mulky A, Cohen TV, Kozlov SV, Korbei B, Foisner R, Stewart CL, KewalRamani VN. The LEM domain proteins emerin and LAP2alpha are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections. J Virol 2008, 82:5860-5868. 10.1128/JVI.00076-08, 2395133, 18400857.
16. Shun MC, Raghavendra NK, Vandegraaff N, Daigle JE, Hughes S, Kellam P, Cherepanov P, Engelman A. LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. Genes Dev 2007, 21:1767-1778. 10.1101/gad.1565107, 1920171, 17639082.
17. Levin A, Rosenbluh J, Hayouka Z, Friedler A, Loyter A. Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins. Mol Med 2010, 16:34-44. 10.2119/molmed.2009.00133, 2765407, 19855849.
18. Zhang Q, Vo N, Goodman RH. Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB. Mol Cell Biol 2000, 20:4970-4978. 10.1128/MCB.20.14.4970-4978.2000, 85947, 10866654.
19. Bladen CL, Udayakumar D, Takeda Y, Dynan WS. Identification of the polypyrimidine tract binding protein-associated splicing factor.p54(nrb) complex as a candidate DNA double-strand break rejoining factor. J Biol Chem 2005, 280:5205-5210. 10.1074/jbc.M412758200, 15590677.
20. Vardabasso C, Manganaro L, Lusic M, Marcello A, Giacca M. The histone chaperone protein Nucleosome Assembly Protein-1 (hNAP-1) binds HIV-1 Tat and promotes viral transcription. Retrovirology 2008, 5:8. 10.1186/1742-4690-5-8, 2266780, 18226242.
21. Terada Y, Yasuda Y. Human immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145. Mol Cell Biol 2006, 26:8149-8158. 10.1128/MCB.01170-06, 1636759, 16923959.
22. Chatel-Chaix L, Clement JF, Martel C, Beriault V, Gatignol A, DesGroseillers L, Mouland AJ. Identification of Staufen in the human immunodeficiency virus type 1 Gag ribonucleoprotein complex and a role in generating infectious viral particles. Mol Cell Biol 2004, 24:2637-2648. 10.1128/MCB.24.7.2637-2648.2004, 371130, 15024055.
23. Mouland AJ, Mercier J, Luo M, Bernier L, DesGroseillers L, Cohen EA. The double-stranded RNA-binding protein Staufen is incorporated in human immunodeficiency virus type 1: evidence for a role in genomic RNA encapsidation. J Virol 2000, 74:5441-5451. 10.1128/JVI.74.12.5441-5451.2000, 112028, 10823848.
24. Milev MP, Brown CM, Mouland AJ. Live cell visualization of the interactions between HIV-1 Gag and the cellular RNA-binding protein Staufen1. Retrovirology 2010, 7:41. 10.1186/1742-4690-7-41, 2887380, 20459747.
25. Steen H, Mann M. The ABC's (and XYZ's) of peptide sequencing. Nat Rev Mol Cell Biol 2004, 5:699-711. 10.1038/nrm1468, 15340378.
26. Cereseto A, Manganaro L, Gutierrez MI, Terreni M, Fittipaldi A, Lusic M, Marcello A, Giacca M. Acetylation of HIV-1 integrase by p300 regulates viral integration. EMBO J 2005, 24:3070-3081. 10.1038/sj.emboj.7600770, 1201351, 16096645.
27. Parissi V, Calmels C, De Soultrait VR, Caumont A, Fournier M, Chaignepain S, Litvak S. Functional interactions of human immunodeficiency virus type 1 integrase with human and yeast HSP60. J Virol 2001, 75:11344-11353. 10.1128/JVI.75.23.11344-11353.2001, 114720, 11689615.
28. Violot S, Hong SS, Rakotobe D, Petit C, Gay B, Moreau K, Billaud G, Priet S, Sire J, Schwartz O, Mouscadet JF, Boulanger P. The human polycomb group EED protein interacts with the integrase of human immunodeficiency virus type 1. J Virol 2003, 77:12507-12522. 10.1128/JVI.77.23.12507-12522.2003, 262565, 14610174.
29. Kalpana GV, Marmon S, Wang W, Crabtree GR, Goff SP. Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science 1994, 266:2002-2006. 10.1126/science.7801128, 7801128.
30. Cherepanov P, Maertens G, Proost P, Devreese B, Van Beeumen J, Engelborghs Y, De Clercq E, Debyser Z. HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. J Biol Chem 2003, 278:372-381. 10.1074/jbc.M209278200, 12407101.
31. Willetts KE, Rey F, Agostini I, Navarro JM, Baudat Y, Vigne R, Sire J. DNA repair enzyme uracil DNA glycosylase is specifically incorporated into human immunodeficiency virus type 1 viral particles through a Vpr-independent mechanism. J Virol 1999, 73:1682-1688. 103999, 9882380.