Design, synthesis and biological evaluation of some novel benzimidazole derivatives for their potential anticonvulsant activity

Archives of Pharmacal Research

Volumn 33, Issue 7, 2010, Pages 971-980

  Jain, Priyal ^a   Sharma, Prakash Kumar ^a   Rajak, Harish ^b   Pawar, Rajesh Singh ^a   Patil, Umesh Kumar ^a   Singour, Pradeep Kumar ^a  

^a VNS Institute of Pharmacy   (India)

^b GURU GHASIDAS UNIVERSITY   (India)

Author keywords

Anticonvulsant; Benzimidazole; MES and PTZ convulsions; QSAR

Indexed keywords

2 (4 CHLORO PHENYL) 5 NITRO 1H BENZIMIDAZOLE; 2 (4 FLUORO PHENYL) 5 NITRO 1H BENZIMIDAZOLE; 2 (4 METHYL PHENYL) 5 NITRO 1H BENZIMIDAZOLE; 4 AMINOBUTYRIC ACID A RECEPTOR; 5 NITRO 2 PYRIDIN 3 YL 1H BENZIMIDAZOLE; ANTICONVULSIVE AGENT; BENZIMIDAZOLE DERIVATIVE; PENTETRAZOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ELECTRIC SHOCK; MALE; NONHUMAN; PHYSICAL CHEMISTRY; RAT; SEIZURE; THERMODYNAMICS;

ANIMALS; ANTICONVULSANTS; BENZIMIDAZOLES; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ELECTROSHOCK; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; SEIZURES;

EID: 77955360270     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-0701-8     Document Type: Article

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