Paraoxonase-3, a putative circulating antioxidant, is systemically up-regulated in late gestation in the fetal rat, sheep, and human

Journal of Clinical Endocrinology and Metabolism

Volumn 95, Issue 8, 2010, Pages 3798-3805

  Belteki, Gusztav ^a,b   Kempster, Sarah L ^a   Forhead, Alison J ^a   Giussani, Dino A ^a   Fowden, Abigail L ^a   Curley, Anna ^b   Charnock Jones, D Stephen ^a   Smith, Gordon C S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE; COMPLEMENTARY DNA; HYDROCORTISONE; PARAOXONASE 3; RNA; UNCLASSIFIED DRUG;

ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; GENE EXPRESSION; GENE SEQUENCE; GESTATIONAL AGE; HUMAN; HUMAN CELL; INTESTINE; LUNG; MICROARRAY ANALYSIS; MOLECULAR CLONING; NONHUMAN; PREGNANCY; PREMATURITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SHEEP; UMBILICAL CORD BLOOD; WESTERN BLOTTING;

EID: 77955358074     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-0037     Document Type: Article

References (22)

1. Clements JA 1997 Lung surfactant: a personal perspective. Annu Rev Physiol 59:1-21
2. Soll RF 2000 Synthetic surfactant for respiratory distress syndrome in preterm infants. Cochrane Database Syst Rev 2:CD001149
3. Brion LP, Bell EF, Raghuveer TS 2003 Vitamin E supplementation for prevention of morbidity and mortality in preterm infants. Cochrane Database Syst Rev 3:CD003665
4. Suresh GK, Davis JM, Soll RF 2001 Superoxide dismutase for preventing chronic lung disease in mechanically ventilated preterm infants. Cochrane Database Syst Rev 1:CD001968
5. Soghier LM, Brion LP 2006 Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates. Cochrane Database Syst Rev 4:CD004869
6. Tan RC, Ikegami M, Jobe AH, Yao LY, Possmayer F, Ballard PL 1999 Developmental and glucocorticoid regulation of surfactant protein mRNAs in preterm lambs. Am J Physiol 277(6 Pt 1):L1142-L1148
7. Mostyn A, Pearce S, Budge H, Elmes M, Forhead AJ, Fowden AL, Stephenson T, Symonds ME 2003 Influence of cortisol on adipose tissue development in the fetal sheep during late gestation. J Endocrinol 176:23-30 (Pubitemid 36163563)
8. Long AD, Mangalam HJ, Chan BY, Tolleri L, Hatfield GW, Baldi P 2001 Improved statistical inference from DNA microarray data using analysis of variance and a Bayesian statistical framework. Analysis of global gene expression in Escherichia coli K12. J Biol Chem 276:19937-19944 (Pubitemid 37411057)
9. Breitling R, Armengaud P, Amtmann A, Herzyk P 2004 Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett 573:83-92 (Pubitemid 39141040)
10. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F 2002 Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034
11. Reddy ST, Wadleigh DJ, Grijalva V, Ng C, Hama S, Gangopadhyay A, Shih DM, Lusis AJ, Navab M, Fogelman AM 2001 Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arterioscler Thromb Vasc Biol 21:542-547 (Pubitemid 32323386)
12. Draganov DI, Stetson PL, Watson CE, Billecke SS, La Du BN 2000 Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation. J Biol Chem 275:33435-33442
13. Peng W, Jiang X, Haiqin L, Zhang C, Zhu J, Zhang J, Zang Y, Qin J 2009 Protective effects of transgene expressed human PON3 against CCl4-induced subacute liver injury in mice. Biomed Pharmacother 63:592-598
14. Shih DM, Xia YR, Wang XP, Wang SS, Bourquard N, Fogelman AM, Lusis AJ, Reddy ST 2007 Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice. Circ Res 100:1200-1207 (Pubitemid 46684133)
15. Heymann MA, Rudolph AM 1975 Control of the ductus arteriosus. Physiol Rev 55:62-78
16. Smith GCS 1998 The pharmacology of the ductus arteriosus. Pharmacol Rev 50:35-58
17. Lyrene RK, Philips 3rd JB 1984 Control of pulmonary vascular resistance in the fetus and newborn. Clin Perinatol 11:551-564 (Pubitemid 14017905)
18. Nathan C 2003 Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. J Clin Invest 111:769-778 (Pubitemid 37074948)
19. Draganov DI, Teiber JF, Speelman A, Osawa Y, Sunahara R, La Du BN 2005 Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. J Lipid Res 46:1239-1247 (Pubitemid 43109838)
20. Hillman NH, Moss TJ, Kallapur SG, Bachurski C, Pillow JJ, Polglase GR, Nitsos I, Kramer BW, Jobe AH 2007 Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep. Am J Respir Crit Care Med 176:575-581 (Pubitemid 47403275)
21. Kallapur SG, Kramer BW, Moss TJ, Newnham JP, Jobe AH, Ikegami M, Bachurski CJ 2003 Maternal glucocorticoids increase endotoxin-induced lung inflammation in preterm lambs. Am J Physiol Lung Cell Mol Physiol 284:L633-L642 (Pubitemid 36343311)
22. Wilson TC, Bachurski CJ, Ikegami M, Jobe AH, Kallapur SG 2005 Pulmonary and systemic induction of Saa3 after ventilation and endotoxin in preterm lambs. Pediatr Res 58:1204-1209