Bacteriophage-resistant Staphylococcus aureus mutant confers broad immunity against staphylococcal infection in mice

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Capparelli, Rosanna ^a   Nocerino, Nunzia ^a   Lanzetta, Rosa ^a   Silipo, Alba ^a   Amoresano, Angela ^a   Giangrande, Chiara ^a   Becker, Karsten ^b   Blaiotta, Giuseppe ^a   Evidente, Antonio ^a   Cimmino, Alessio ^a   Iannaccone, Marco ^a   Parlato, Marianna ^a   Medaglia, Chiara ^a   Roperto, Sante ^a   Roperto, Franco ^a   Ramunno, Luigi ^a   Iannelli, Domenico ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; GALACTOSE; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 1BETA; N ACETYLGLUCOSAMINE; POLYSACCHARIDE; SUGAR; TUMOR NECROSIS FACTOR ALPHA; BACTERIUM ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ANTIBODY TITER; ARTICLE; BACTERIAL IMMUNITY; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BACTERIUM MUTANT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; FEMALE; IN VIVO STUDY; INFECTION PREVENTION; LETHAL DOSE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; STAPHYLOCOCCUS INFECTION; STAPHYLOCOCCUS PHAGE; TRANSCRIPTION REGULATION; VACCINE PRODUCTION; ANIMAL; BACTERIOPHAGE; BAGG ALBINO MOUSE; BLOOD; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; LIQUID CHROMATOGRAPHY; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; PULSED FIELD GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; VIROLOGY;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS; STAPHYLOCOCCUS AUREUS;

ACETYLGLUCOSAMINE; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; BACTERIOPHAGES; CHROMATOGRAPHY, LIQUID; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICE, INBRED BALB C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 77955354281     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011720     Document Type: Article

References (48)

1. Boyce JM (2005) Meticillin-resistant Staphylococcus aureus. Lancet Infect Dis 5: 653-654.
2. Marris E (2005) Bugs gain vital ground in their battle against drugs. Nat Med 11: 461.
3. Miller LG, Perdreau-Remington F, Rieg G, Mahdi GS, Perlroth JA, et al. (2005) Necrotising fasciitis caused by community-associated methicillin resistant Staphylococcus aureus in Los Angeles. N Engl J Med 352: 1445-1453.
4. Sakoulas G, Eliopoulos GM, Fowler Jr. VG, Moellering Jr. RC, Novick R, et al. (2005) Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbial protein correlates with defective autolysis and loss of accessory gene regulator (agr) function. Antimicrob Agents Chemother 49: 2687-2692.
5. Lowy FD (1988) Staphylococcus aureus infections. N Engl J Med 339: 520-532.
6. Zahid MS, Udden SM, Faruque AS, Calderwood SB, Mekalanos JJ, et al. (2008) Effect of phage on the infectivity of Vibrio cholerae and emergence of genetic variants. Infect Immun 76: 5266-5273.
7. Jensen MA, Faruq SM, Mekalanos JJ, Levin BR (2006) Modeling the role of bacteriophage in the control of cholera outbreaks. Proc Ntl Acad Sci USA 103: 4652-4657.
8. Scott AE, Timms AR, Connerton PL, Carrillo CL, Radzum KA, et al. (2007) Genome dynamics of Campylobacter jejuni in response to bacteriophage predation. PLOS Pathogens 3: 1142-1151.
9. Mason W.J., Blevins J, Beenken K, Wibowo N, Ojma N, et al. (2001) Multiplex PCR protocol for the diagnosis of staphylococcal infections. J Clin Microbiol 39: 3332-3338.
10. Capparelli R, Parlato M, Borriello G, Salvatore P, Iannelli D (2007) Experimental phage therapy against Staphylococcus aureus in mice. Antimicrob Agents Chemother 51: 2765-2773.
11. Lachica V, Genigeorgis C, Hoeprich P (1979) Occurrence of protein A in Staphylococcus aureus and closely related Staphylococcus species. J Clin Microbiol 10: 752-753.
12. Peschel A, Otto M, Jack RW, Kalbacher H, Jung G, et al. (1999) Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides. J Biol Chem 274: 8405-8410.
13. Ciucanu I, Kerek F (1984) A simple method for the permethylation of carbohydrates. Carbohydr Res 131: 209-217.
14. Cimmino A, Marchi G, Surico G, Hanuszkiewicz A, Evidente A, Holst O (2008) The structure of the O-specific polysaccharide of the lipopolysaccharide from Pantoa agglomerata strain FL1. Carbohydrate Res 343: 392-396.
15. Korman R (1975) Cell wall composition of novobiocin-resistant pleiotropic mutant staphylococci. J Bact 124: 724-730.
16. Luria SE, Delbruck M (1943) Mutations of bacteria from virus sensitive to virus resistance. Genetics 28: 491-511.
17. Blaiotta G, Moschetti G, Simeoli E, Andolfi R, Villani F, et al. (2001) Monitoring lactic acid bacteria strains during ''cacioricotta'' cheese production by restriction endonucleases analysis and pulsed-field gel electrophoresis. J Dairy Res 68: 139-144.
18. Capparelli R, Nocerino N, Iannaccone M, Ercolini D, Parlato M, et al. (2009) Phage therapy of Salmonella enterica: a fresh appraisal of phage therapy. J Infect Dis 201: 52: 52-61.
19. Weidenmaier C, Kokai-Kun J, Kristian SA, Chanturiya T.H., Kalbacher H, et al. (2004) Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections. Nat Med 10: 243-245.
20. Mellmann A, Friedrich AW, Rosenkotter N, Rothganger J, Karch H, et al. (2006) Automated DNA sequence-based early warning system for the detection of methicillin-resistant Staphylococcus aureus outbreaks. PLoS Med 3: e33.
21. Enright MC, Day NP, Davies CE, Peacock SJ, Spratt BG (2000) Multilocus sequence typing for characterization of methicillin-resistant and methicillinsusceptible clones of Staphylococcus aureus. J Clin Microbiol 38: 1008-15.
22. Blaiotta G, Ercolini D, Pennacchia C, Fusco V, Casaburi A, et al. (2004) PCR detection of staphylococcal enterotoxin genes in Staphylococcus spp. strains isolated from meat and dairy products. Evidence for new variants of seG and seI in S. aureus AB-8802. J Appl Microbiol 97: 719-730.
23. Blaiotta G, Fusco V, von Eiff C, Villani F, Becker K (2006) Biotyping of enterotoxigenic Staphylococcus aureus by enterotoxin gene cluster (egc) polymorphism and spa typing analyses. Appl Environ Microbiol 72: 6117-6123.
24. Sanderson A, Strominger J, Nathenson S (1962) Chemical structure of Teichoic acid from Staphylococcus aureus, strain Copenhagen. J Biol Chem 237: 3603-3613.
25. McCallum N, Karauzum H, Getzmann R, Bischoff M, Majcherczyk P, et al. (2006) In vivo survival of teicoplanin-resistant Staphylococcus aureus and fitness cost of teicoplanin resistance. Antimicrob Agents Chemother 50: 2352-2360.
26. Glaser L, Ionesco H, Schaeffer P (1966) Teichoic acids as components of a specific phage receptor in Bacillus subtilis. Biochem Biophys Acta 124: 415-417.
27. Young FE (1967) Requirement of glucosylated teichoic acid for adsorption of phage in Bacillus subtilis 168. Proc Natl Acad Sci USA 58: 2377-2384.
28. Coyette JJ, Ghuysen M (1968) Structure of the cell wall of Staphylococcus aureus, strain Copenhagen. IX. Teichoic acid and phage adsorption. Biochemistry 7: 2385-2389.
29. Baggesen D, Wegener H, Madsen M (1997) Correlation of conversion of Salmonella enterica serovar enteritidis phage type 1, 4 or 6 to phage 7 with loss of lipopolysaccharide. J Clin Microbiol 35: 330-333.
30. Goerke C, Gressinger M, Endler K, Breitkopt C, Wardechi CK, et al. (2007) High phenotypic diversity in infecting but not in colonizing Staphylococcus aureus populations. Environm Microbiol 9: 3134-3142.
31. Wardenburg JB, Schneewind O (2008) Vaccine protection against Staphylococcus aureus pneumonia. J Exp Med 205: 287-294.
32. Goodner K, Horsfall F (1935) The protective action of Type 1 antipneumococcus serum in mice. I. Quantitative aspects of the protection test. J Exp Med 62: 359-374.
33. Taborda C, Rivera J, Zaragoza O, Casadevall A (2003) More is not necessarily better: prozone-like effects in passive immunization IgG. J Immunol 170: 3621-3630.
34. Sparano JA, Wolf A, Brown D (2000) Troponins for predicting cardiotoxicity from cancer therapy. Lancet 356: 1947-1948.
35. Yeh ET (2006) Cardiotoxicity induced by chemotherapy and antibody therapy. Ann Rev Med 57: 485-498.
36. Dinarello CA (1996) Cytokines as mediators in pathogenesis of septic shock. In Pathology of septic shock. Current Topics in Microbiology and Immunology. Vol 216 ERietschel, HWagner, eds. Berlin: Springer-Verlag. pp 133-165.
37. Hu DL, Omoe H, Sasaki S, Sashinami H, Sakuraba H, et al. (2003) Vaccination with non-toxic mutant toxic shock syndrome toxin I protects against Staphylococcus aureus infection. J Infect Dis 188: 743-752.
38. Nilsson IM, Patti JM, Bremell T, Hook TM, Tarkowski A (1998) Vaccination with a recombinant fragment of collagen adhesion provides protection against Staphylococcus aureus-mediated septic death. J Clin Invest 101: 2640-2649.
39. Kuklin N, Clark D, Secore S, Cook J, Cope L (2006) A novel Staphylococcus aureus vaccine: iron surface determinant B induces rapid antibody response in rhesus macaques and specific increased survival in a murine S. aureus sepsis model. Infect Immun 74: 2215-2223.
40. Telford JL (2008) Bacterial genome variability and its impact on vaccine design. Cell Host & Microbe 3: 408-416.
41. Winzeler EA (2008) Malaria research in the post-genomic era. Nature 455: 751-756.
42. Bohannan BJ, Lenski RE (2000) Linking genetic change to community evolution: insights from studies of bacteria and bacteriophage. Ecol Lett 3: 362-377.
43. Labrie S, Samson J, Moineau S (2010) Bacteriophage resistance mechanisms. Nat Rev Microbiology 8: 317-327.
44. Hormaeche CE, Joisey H, Desilva L, Izhar M, Stocker MB (1991) Immunity conferred by Aro-Salmonella live vaccines. Microb Pathog 10: 149-158.
45. McKenney D, Kimberley L, Pouliot L, Wang Y, Murthy V, et al. (1999) Broadly protective vaccine for Staphylococcus aureus based on an in vivo-expressed antigen. Science 284: 1523-1527.
46. O'Riordan K, Lee J (2004) Staphylococcus aureus capsular polysaccharides. Clin Microbiol Rev 17: 218-234.
47. Middelboc M, Hamstrong A, Blackburn N, Sinn R, Fischer U, et al. (2001) Effect of bacteriophage on the population dynamics of four strains of pelagic marine bacteria. Microb Ecol 42: 395-406.
48. Lederberg J (1996) Smaller fleasad infinitum: therapeutic bacteriophage redux. Proc Ntl Acad Sci USA 93: 3167-3168.