Possible involvement and the mechanisms of excess trans-fatty acid consumption in severe NAFLD in mice

Journal of Hepatology

Volumn 53, Issue 2, 2010, Pages 326-334

  Obara, Noriyuki ^a   Fukushima, Koji ^a   Ueno, Yoshiyuki ^a   Wakui, Yuta ^a   Kimura, Osamu ^a   Tamai, Keiichi ^a   Kakazu, Eiji ^a   Inoue, Jun ^a   Kondo, Yasuteru ^a   Ogawa, Norihiko ^a   Sato, Kenta ^b   Tsuduki, Tsuyoshi ^b   Ishida, Kazuyuki ^c   Shimosegawa, Tooru ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

Kupffer cell; Metabolic syndrome; NAFLD; NASH; trans Fatty acid

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ALANINE AMINOTRANSFERASE; ARACHIDONIC ACID; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CD11B ANTIGEN; CIS FATTY ACID; COLLAGEN TYPE 1; ELAIDIC ACID; FAS ANTIGEN; FATTY ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROGENATED VEGETABLE OIL; INTERLEUKIN 6; LEPTIN; LINOLEIC ACID; LIPID PEROXIDE; MESSENGER RNA; MYELOPEROXIDASE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROTEIN KINASE B; RAPESEED OIL; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANS FATTY ACID; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR; VERY LOW DENSITY LIPOPROTEIN; ADIPOCYTOKINE; CYTOKINE; FAT INTAKE; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CELL CULTURE; CELL ISOLATION; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FEMALE; GAS CHROMATOGRAPHY; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KUPFFER CELL; LIPID COMPOSITION; LIPID DIET; LIPID LIVER LEVEL; LIPID STORAGE; LIPIDOMICS; LIVER HISTOLOGY; LIVER WEIGHT; MOUSE; NICK END LABELING; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOGENESIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; ANIMAL; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; FAT INTAKE; FATTY LIVER; LIPID METABOLISM; LIPID PEROXIDATION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADIPOKINES; ANIMALS; CELLS, CULTURED; CYTOKINES; DIETARY FATS; DISEASE MODELS, ANIMAL; FATTY LIVER; FEMALE; KUPFFER CELLS; LIPID METABOLISM; LIPID PEROXIDATION; MICE; MICE, INBRED C57BL; PHAGOCYTOSIS; PROTO-ONCOGENE PROTEINS C-AKT; TRANS FATTY ACIDS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77955303797     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.02.029     Document Type: Article

References (33)

1. B.M. Babior Oxygen-dependent microbial killing by phagocytes (first of two parts) N Engl J Med 298 1978 659 668
2. J.D. Browning, L.S. Szczepaniak, R. Dobbins, P. Nuremberg, J.D. Horton, and J.C. Cohen Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity Hepatology 40 2004 1387 1395
3. R. Buettner, K.G. Parhofer, M. Woenckhaus, C.E. Wrede, L.A. Kunz-Schughart, and J. Scholmerich Defining high-fat-diet rat models: metabolic and molecular effects of different fat types J Mol Endocrinol 36 2006 485 501
4. H. Cao, K. Gerhold, J.R. Mayers, M.M. Wiest, S.M. Watkins, and G.S. Hotamisligil Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism Cell 134 2008 933 944
5. C.P. Day, and O.F. James Steatohepatitis: a tale of two "hits"? Gastroenterology 114 1998 842 845
6. Q.G. Deng, H. She, J.H. Cheng, S.W. French, D.R. Koop, and S. Xiong Steatohepatitis induced by intragastric overfeeding in mice Hepatology 42 2005 905 914
7. K.L. Donnelly, C.I. Smith, S.J. Schwarzenberg, J. Jessurun, M.D. Boldt, and E.J. Parks Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease J Clin Invest 115 2005 1343 1351
8. D.E. Duque-Guimaraes, J. de Castro, J. Martinez-Botas, F.L. Sardinha, M.P. Ramos, and E. Herrera Early and prolonged intake of partially hydrogenated fat alters the expression of genes in rat adipose tissue Nutrition 25 2009 782 789
9. G.C. Farrell, and C.Z. Larter Nonalcoholic fatty liver disease: from steatosis to cirrhosis Hepatology 43 2006 S99 S112
10. J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipides from animal tissues J Biol Chem 226 1957 497 509
11. A. Gonzalez-Periz, R. Horrillo, N. Ferre, K. Gronert, B. Dong, and E. Moran-Salvador Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins FASEB J 23 2009 1946 1957
12. S.N. Han, L.S. Leka, A.H. Lichtenstein, L.M. Ausman, E.J. Schaefer, and S.N. Meydani Effect of hydrogenated and saturated, relative to polyunsaturated, fat on immune and inflammatory responses of adults with moderate hypercholesterolemia J Lipid Res 43 2002 445 452
13. H. Honda, K. Ikejima, M. Hirose, M. Yoshikawa, T. Lang, and N. Enomoto Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver Hepatology 36 2002 12 21
14. A. Ibrahim, S. Natrajan, and R. Ghafoorunissa Dietary trans-fatty acids alter adipocyte plasma membrane fatty acid composition and insulin sensitivity in rats Metabolism 54 2005 240 246
15. S. Kechagias, A. Ernersson, O. Dahlqvist, P. Lundberg, T. Lindstrom, and F.H. Nystrom Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects Gut 57 2008 649 654
16. D.E. Kleiner, E.M. Brunt, M. Van Natta, C. Behling, M.J. Contos, and O.W. Cummings Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 41 2005 1313 1321
17. S.W. Koppe, M. Elias, R.H. Moseley, and R.M. Green Trans fat feeding results in higher serum alanine aminotransferase and increased insulin resistance compared with a standard murine high-fat diet Am J Physiol Gastrointest Liver Physiol 297 2009 G378 G384
18. C.Z. Larter, M.M. Yeh, W.G. Haigh, J. Williams, S. Brown, and K.S. Bell-Anderson Hepatic free fatty acids accumulate in experimental steatohepatitis: role of adaptive pathways J Hepatol 48 2008 638 647
19. J. Lin, R. Yang, P.T. Tarr, P.H. Wu, C. Handschin, and S. Li Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP Cell 120 2005 261 273
20. E. Lopez-Garcia, M.B. Schulze, J.B. Meigs, J.E. Manson, N. Rifai, and M.J. Stampfer Consumption of trans fatty acids is related to plasma biomarkers of inflammation and endothelial dysfunction J Nutr 135 2005 562 566
21. H. Malhi, and G.J. Gores Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease Semin Liver Dis 28 2008 360 369
22. R.P. Mensink, P.L. Zock, A.D. Kester, and M.B. Katan Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials Am J Clin Nutr 77 2003 1146 1155
23. F.I. Milagro, J. Campion, and J.A. Martinez Weight gain induced by high-fat feeding involves increased liver oxidative stress Obesity (Silver Spring) 14 2006 1118 1123
24. P. Puri, R.A. Baillie, M.M. Wiest, F. Mirshahi, J. Choudhury, and O. Cheung A lipidomic analysis of nonalcoholic fatty liver disease Hepatology 46 2007 1081 1090
25. A.E. Reid Nonalcoholic steatohepatitis Gastroenterology 121 2001 710 723
26. J.B. Schwimmer, C. Behling, R. Newbury, R. Deutsch, C. Nievergelt, and N.J. Schork Histopathology of pediatric nonalcoholic fatty liver disease Hepatology 42 2005 641 649
27. H. Shimano, J.D. Horton, R.E. Hammer, I. Shimomura, M.S. Brown, and J.L. Goldstein Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a J Clin Invest 98 1996 1575 1584
28. G.L. Su, R.D. Klein, A. Aminlari, H.Y. Zhang, L. Steinstraesser, and W.H. Alarcon Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4 Hepatology 31 2000 932 936
29. Q. Sun, J. Ma, H. Campos, S.E. Hankinson, J.E. Manson, and M.J. Stampfer A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease Circulation 115 2007 1858 1865
30. L.H. Tetri, M. Basaranoglu, E.M. Brunt, L.M. Yerian, and B.A. Neuschwander-Tetri Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent Am J Physiol Gastrointest Liver Physiol 295 2008 G987 G995
31. T. Tsuzuki, Y. Tokuyama, M. Igarashi, K. Nakagawa, Y. Ohsaki, and M. Komai Alpha-eleostearic acid (9Z11E13E-18:3) is quickly converted to conjugated linoleic acid (9Z11E-18:2) in rats J Nutr 134 2004 2634 2639
32. K. Yamaguchi, L. Yang, S. McCall, J. Huang, X.X. Yu, and S.K. Pandey Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis Hepatology 45 2007 1366 1374
33. Y.L. Zhang, A. Hernandez-Ono, P. Siri, S. Weisberg, D. Conlon, and M.J. Graham Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis J Biol Chem 281 2006 37603 37615