Novel short antibacterial and antifungal peptides with low cytotoxicity: Efficacy and action mechanisms

Biochemical and Biophysical Research Communications

Volumn 398, Issue 3, 2010, Pages 594-600

  Qi, Xiaobao ^a   Zhou, Chuncai ^a   Li, Peng ^a   Xu, Weixin ^b   Cao, Ye ^a   Ling, Hua ^a   Ning Chen, Wei ^a   Ming Li, Chang ^a   Xu, Rong ^a   Lamrani, Mouad ^c   Mu, Yuguang ^b   Leong, Susanna Su Jan ^a   Wook Chang, Matthew ^a   Chan Park, Mary B ^a  

^a Nanyang Technological University   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c MENICON CO LTD   (Japan)

Author keywords

Helix; Antimicrobial peptides; Hydrophobicity; Pathogens

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ARGININE; DYE; GLYCINE; ISOLEUCINE; LEUCINE; LYSINE; MEMBRANE LIPID; PEPTIDE DERIVATIVE; PHENYLALANINE;

AMINO ACID SEQUENCE; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; ESCHERICHIA COLI; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; FUSARIUM SOLANI; HEMOLYSIS; HUMAN; HUMAN CELL; LIPID BILAYER; MEMBRANE DEPOLARIZATION; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SIMULATION; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; CANDIDA ALBICANS; FUSARIUM; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR DYNAMICS SIMULATION;

BACTERIA (MICROORGANISMS); CANDIDA ALBICANS; ESCHERICHIA COLI; FUSARIUM SOLANI; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 77955279662     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.06.131     Document Type: Article

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