Tuning the biological properties of amphipathic α-helical antimicrobial peptides: Rational use of minimal amino acid substitutions

Peptides

Volumn 26, Issue 12, 2005, Pages 2368-2376

  Zelezetsky, Igor ^a   Pag, Ulrike ^b   Sahl, Hans Georg ^b   Tossi, Alessandro ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Alpha helix; Antimicrobial peptide; Cytotoxicity; Sequence template

Indexed keywords

PEPTIDE DERIVATIVE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM; BIOLOGICAL ACTIVITY; CONFORMATION; CYTOLYSIS; CYTOTOXICITY; ERYTHROCYTE; FUNGAL STRAIN; HYDROPHOBICITY; KINETICS; MEMBRANE PERMEABILITY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; YEAST;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BACTERIA; CIRCULAR DICHROISM; ERYTHROCYTE MEMBRANE; HUMANS; HYDROPHOBICITY; MICROBIAL SENSITIVITY TESTS; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS);

EID: 27944443662     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2005.05.002     Document Type: Article

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