Magnesium gating of cardiac gap junction channels

Progress in Biophysics and Molecular Biology

Volumn 103, Issue 1, 2010, Pages 102-110

  Matsuda, Hiroyuki ^a   Kurata, Yasutaka ^b   Oka, Chiaki ^a   Matsuoka, Satoshi ^a   Noma, Akinori ^a,c  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

Arrhythmia; Chemical gating; Gap junction channel; Numerical ventricular cell model

Indexed keywords

CAVIA;

EID: 77955278083     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbiomolbio.2010.05.009     Document Type: Review

References (40)

1. Akar F.G., Nass R.D., Hahn S., Cingolani E., Shah M., Hesketh G.G., DiSilvestre D., Tunin R.S., Kass D.A., Tomaselli G.F. Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure. Am. J. Physiol. Heart. Circ. Physiol. 2007, 293:H1223-H1230.
2. Beardslee M.A., Laing J.G., Beyer E.C., Saffitz J.E. Rapid turnover of Connexin 43 in the adult rat heart. Circ. Res. 1998, 83:629-635.
3. Brink P.R., Fan S.F. Patch clamp recordings from membranes which contain gap junction channels. Biophys. J. 1989, 56:579-593.
4. Bukauskas F.F., Verselis V.K. Gap junction channel gating. Biochim. Biophys. Acta 2004, 1662:42-60.
5. Carmeliet E. Cardiac ionic currents and acute ischemia: from channels to arrhythmia. Physiol. Rev. 1999, 79:917-1017.
6. Desplantez T., Dupont E., Severs N.J., Weingart R. Gap junction channels and cardiac impulse propagation. J. Membr. Biol. 2007, 218:13-28.
7. Dhein S. Pharmacology of gap junctions in the cardiovascular system. Cardiovasc. Res. 2004, 62:287-298.
8. Eloff B.C., Gilat E., Wan X., Rosenbaum D.S. Pharmacological modulation of cardiac gap junctions to enhance cardiac conduction: evidence supporting a novel target for antiarrhythmic therapy. Circulation 2003, 108:3157-3163.
9. Firek L., Weingart R. Modification of gap junction conductance by divalent cations and protons in neonatal rat heart cells. J. Mol. Cell. Cardiol. 1995, 27:1633-1643.
10. Gomez M.N. Magnesium and cardiovascular disease. Anesthesiology 1998, 89:222-240.
11. González D., Gómez-Hernández J.M., Barrio L.C. Molecular basis of voltage dependence of connexin channels: an integrative appraisal. Prog. Biophys. Mol. Biol. 2007, 94:66-106.
12. Grubbs R.D. Intracellular magnesium and magnesium buffering. Biometals 2002, 15:251-259.
13. 2+ in cardiac myocytes. J. Gen. Physiol. 2008, 132:721-730.
14. Haigney M.C., Wei S., Kaab S., Griffiths E., Berger R., Tunin R., Kass D., Fisher W.G., Silver B., Silverman H. Loss of cardiac magnesium in experimental heart failure prolongs and destabilizes repolarization in dogs. J. Am. Coll. Cardiol. 1998, 31:701-706.
15. Harada M., Honjo H., Yamazaki M., Nakagawa H., Ishiguro Y.S., Okuno Y., Ashihara T., Sakuma I., Kamiya K., Kodama I. Moderate hypothermia increases the chance of spiral wave collision in favor of self-termination of ventricular tachycardia/fibrillation. Am. J. Physiol. Heart. Circ. Physiol. 2008, 294:H1896-H1905.
16. Harris A.L. Emerging issues of connexin channels: biophysics fills the gap. Q. Rev. Biophys. 2001, 34:325-472.
17. Hoshino K., Ogawa K., Hishitani T., Isobe T., Etoh Y. Successful uses of magnesium sulfate for torsades de pointes in children with long QT syndrome. Pediatr. Int. 2006, 48:112-117.
18. + current in cardiac repolarization reserve: a quantitative simulation. J. Mol. Cell. Cardiol. 2009, 47:76-84.
19. Kameyama M. Electrical coupling between ventricular paired cells isolated from guinea-pig heart. J. Physiol. 1983, 336:345-357.
20. Kasaoka S., Tsuruta R., Nakashima K., Soejima Y., Miura T., Sadamitsu D., Tateishi A., Maekawa T. Effect of intravenous magnesium sulfate on cardiac arrhythmias in critically ill patients with low serum ionized magnesium. Jpn. Circ. J. 1996, 60:871-875.
21. - homeostasis during β1-adrenergic stimulation of cardiac myocyte. Prog. Biophys. Mol. Biol. 2008, 96:171-186.
22. Lurtz M.M., Louis C.F. Intracellular calcium regulation of connexin43. Am. J. Physiol. Cell Physiol. 2007, 293:C1806-C1813.
23. Michailova A., McCulloch A. Model study of ATP and ADP buffering, transport of Ca(2+) and Mg(2+), and regulation of ion pumps in ventricular myocyte. Biophys. J. 2001, 81:614-629.
24. Mitra R., Morad M. A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates. Am. J. Physiol. 1985, 249:H1056-H1060.
25. Mubagwa K., Gwanyanya A., Zakharov S., Macianskiene R. Regulation of cation channels in cardiac and smooth muscle cells by intracellular magnesium. Arch. Biochem. Biophys. 2007, 458:73-89.
26. Murphy E., Steenbergen C., Levy L.A., Raju B., London R.E. Cytosolic free magnesium levels in ischemic rat heart. J. Biol. Chem. 1989, 264:5622-5627.
27. Musso C.G. Magnesium metabolism in health and disease. Int. Urol. Nephrol. 2009, 41:357-362.
28. Noma A., Tsuboi N. Dependence of junctional conductance of proton, calcium and magnesium ions in cardiac paired cells of guinea-pig. J. Physiol. 1987, 382:193-211.
29. Oka C., Matsuda H., Sarai N., Noma A. Modelling the calcium gate of cardiac gap junction channel. J. Physiol. Sci. 2006, 56:79-85.
30. Oliveira-Castro G.M., Loewenstein W.R. Junctional membrane permeability. Effects of divalent cations. J. Membrane. Biol. 1971, 5:51-77.
31. Onalan O., Crystal E., Daoulah A., Lau C., Crystal A., Lashevsky I. Meta-analysis of magnesium therapy for the acute management of rapid atrial fibrillation. Am. J. Cardiol. 2007, 99:1726-1732.
32. Peracchia C. Chemical gating of gap junction channels roles of calcium, PH and calmodulin. Biochim. Biophys. Acta. 2004, 1662:61-80.
33. Rossi S., Baruffi S., Bertuzzi A., Miragoli M., Corradi D., Maestri R., Alinovi R., Mutti A., Musso E., Sgoifo A., Brisinda D., Fenici R., Macchi E. Ventricular activation is impaired in aged rat hearts. Am. J. Physiol. Heart. Circ. Physiol. 2008, 295:H2336-H2347.
34. Shi J., Krishnamoorthy G., Yang Y., Hu L., Chaturvedi N., Harilal D., Qin J., Cui J. Mechanism of magnesium activation of calcium-activated potassium channels. Nature 2002, 418:876-880.
35. Sugiura H., Toyama J., Tsuboi N., Kamiya K., Kodama I. ATP directly affects junctional conductance between paired ventricular myocytes isolated from guinea pig heart. Circ. Res. 1990, 66:1095-1102.
36. Swietach P., Rossini A., Spitzer K.W., Vaughan-Jones R.D. H+ ion activation and inactivation of the ventricular gap junction: a basis for spatial regulation of intracellular pH. Circ. Res. 2007, 100:1045-1054.
37. Toyama J., Sugiura H., Kamiya K., Kodama I., Terasawa M., Hidaka H. Ca2+ -calmodulin mediated modulation of the electrical coupling of ventricular myocytes isolated from guinea pig heart. J. Mol. Cell. Cardiol. 1994, 26:1007-1015.
38. Veenstra R.D., Dehaan R.L. Cardiac gap junction channel activity in embryonic chick ventricle cells. Am. J. Physiol. 1988, 254:H170-H180.
39. 2+ is a voltage-dependent pore blocker of HCN channels. Am. J. Physiol. Cell Physiol. 2008, 295:C557-C565.
40. 2+ concentration. Am. J. Physiol. Cell Physiol. 2006, 291:C83-C92.