Modeling the calcium gate of cardiac gap junction channel

Journal of Physiological Sciences

Volumn 56, Issue 1, 2006, Pages 79-85

  Oka, Chiaki ^a   Matsuda, Hiroyuki ^a   Sarai, Nobuaki ^a   Noma, Akinori ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Gap junction; Heart; Mathematical model

Indexed keywords

CALCIUM CHANNEL;

ARTICLE; CALCIUM CONDUCTANCE; GAP JUNCTION; MODEL; ACTION POTENTIAL; ANIMAL; CELL JUNCTION; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHEMISTRY; CYTOLOGY; HEART; HEART ARRHYTHMIA; HEART MUSCLE; HUMAN; KINETICS; PATHOPHYSIOLOGY; PHYSIOLOGY; THEORETICAL MODEL; TIME;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIA; CALCIUM CHANNELS; GAP JUNCTIONS; HEART; HUMANS; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MODELS, THEORETICAL; MYOCARDIUM; TIME FACTORS;

EID: 33745607929     PISSN: 18806546     EISSN: None     Source Type: Journal    
DOI: 10.2170/physiolsci.R2139     Document Type: Article

References (23)

1. Rohr S. Role of gap junctions in the propagation of the cardiac action potential. Cardiovasc Res. 2004;62:309-22.
2. Bukauskas FF, Verselis VK. Gap junction channel gating. Biochim Biophys Acta. 2004;1662: 42-60.
3. Peracchia C. Chemical gating of gap junction channels; roles of calcium, pH and calmodulin. Biochim Biophys Acta. 2004;1662: 61-80.
4. Noma A, Tsuboi N. Dependence of junctional conductance on proton, calcium and magnesium ions in cardiac paired cells of guinea-pig. J Physiol. 1987;382:193-211.
5. Sugiura H, Toyama J, Tsuboi N, Kamiya K, Kodama I. ATP directly affects junctional conductance between paired ventricular myocytes isolated from guinea pig heart. Circ Res. 1990;66:1095-102.
6. Deleze J. The recovery of resting potential and input resistance in sheep heart injured by knife or laser. J Physiol. 1970;208:547-62.
7. Weingart R. The actions of ouabain on intercellular coupling and conduction velocity in mammalian ventricular muscle. J Physiol. 1977;264:341-65.
8. Kleber AG, Riegger CB, Janse MJ. Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle. Circ Res. 1987;61:271-9.
9. Hiramatsu Y, Buchanan JW, Jr., Knisley SB, Koch GG, Kropp S, Gettes LS. Influence of rate-dependent cellular uncoupling on conduction change during simulated ischemia in guinea pig papillary muscles: effect of verapamil. Circ Res. 1989;65:95-102.
10. Weidmann S. Electrical constants of trabecular muscle from mammalian heart. J Physiol. 1970;210:1041-54.
11. Oka C, Matsuda H, Sarai N, Matsuoka S, Noma A. Dependency of myocardial function on gap junction conductance. Jpn J Physiol 55 Suppl. 2005:S90.
12. Henriquez AP, Vogel R, Muller-Borer BJ, Henriquez CS, Weingart R, Cascio WE. Influence of dynamic gap junction resistance on impulse propagation in ventricular myocardium: a computer simulation study. Biophys J. 2001;81:2112-21.
13. Vogel R, Weingart R. Mathematical model of vertebrate gap junctions derived from electrical measurements on homotypic and heterotypic channels. J Physiol. 1998;510 ( Pt 1):177-89.
14. Matsuoka S, Sarai N, Kuratomi S, Ono K, Noma A. Role of individual ionic current systems in ventricular cells hypothesized by a model study. Jpn J Physiol. 2003;53:105-23.
15. Sarai N, Matsuoka S, Noma A. simBio: A Java package for the development of detailed cell models. Prog Biophys Mol Biol. 2006; 90:360-77.
16. Kameyama M. Electrical coupling between ventricular paired cells isolated from guinea-pig heart. J Physiol. 1983;336:345-57.
17. Beaumont J, Davidenko N, Davidenko JM, Jalife J. Spiral waves in twodimensional models of ventricular muscle: formation of a stationary core. Biophys J 1998;75: 1-14.
18. Clayton RH, Bailey A, Biktashev VN, Holden AV. Re-entrant cardiac arrhythmias in computational models of long QT myocardium. J Theor Biol. 2001;208:215-25.
19. Sampson KJ, Henriquez CS. Electrotonic influences on action potential duration dispersion in small hearts: a simulation study. Am J Physiol Heart Circ Physiol. 2005;289:H350-60.
20. i on nexal membrane resistance. Pflugers Arch. 1987;409:394-402.
21. Lazrak A, Peracchia C. Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells. Biophys J. 1993;65: 2002-12.
22. Firek L, Weingart R. Modification of gap junction conductance by divalent cations and protons in neonatal rat heart cells. J Mol Cell Cardiol. 1995;27:1633-43.
23. Mathias RT, Cohen IS, Oliva C. Limitations of the whole cell patch clamp technique in the control of intracellular concentrations. Biophys J 1990;58: 759-70.