New anti-fibrotic mechanisms of n-acetyl-seryl-aspartyl-lysyl-proline in silicon dioxide-induced silicosis

Life Sciences

Volumn 87, Issue 7-8, 2010, Pages 232-239

  Sun, Ying ^a   Yang, Fang ^a   Yan, Jingbo ^a   Li, Qian ^a   Wei, Zhongqiu ^a   Feng, Haili ^a   Wang, Ruimin ^a   Zhang, Lijuan ^a   Zhang, Xuepeng ^a  

^a NORTH CHINA COAL MEDICAL COLLEGE   (China)

Author keywords

Ac SDKP; Fibroblasts; Macrophages; Silicosis

Indexed keywords

ACETYLSERYLASPARTYLLYSYL PROLINE; AMINO ACID DERIVATIVE; ANTIFIBROTIC AGENT; COLLAGEN TYPE 1; COLLAGEN TYPE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; SILICON DIOXIDE; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG FIBROBLAST; MALE; NONHUMAN; OSMOTIC PUMP; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SILICOSIS; WESTERN BLOTTING;

ANIMALS; CELL MIGRATION INHIBITION; CELL PROLIFERATION; CHEMOKINE CCL2; COLLAGEN; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MACROPHAGES; MALE; OLIGOPEPTIDES; PROTEIN TRANSPORT; RATS; RATS, WISTAR; SILICON DIOXIDE; SILICOSIS; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALIA; RATTUS;

EID: 77955274084     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.06.016     Document Type: Article

References (45)

1. Adler V., Pincus M.R., Minamoto T., Fuchs S.Y., Bluth M.J., Brandt-Rauf P.W., Friedman F.K., Robinson R.C., Chen J.M., Wang X.W., Harris C.C., Ronai Z. Conformation-dependent phosphorylation of p53. Proceedings of the National Academy of Sciences of the United States of America 1997, 94:1686-1691.
2. Ajuebor M.N., Flower R.J., Hannon R., Christie M., Bowers K., Verity A., Perretti M. Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model. Journal of Leukocyte Biology 1998, 63:108-116.
3. Azizi M., Ezan E., Nicolet L., Grognet J.M., Menard J. High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: a new marker of chronic angiotensin-converting enzyme inhibition. Hypertension 1997, 30:1015-1019.
4. Balaan M.R., Banks D.E. Silicosis. Environmental and Occupational Medicine 1998, 345-358. little Brown, Boston, MA. 3rd ed. W.N. Rom (Ed.).
5. Binaya R., Alissa K.G., William N.R. Basic pathogenetic mechanisms in silicosis: current understanding. Current Opinion in Pulmonary Medicine 2005, 11:169-173.
6. Bogoyevitch M.A., Kobe B. Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases. Microbiology and Molecular Biology Reviews 2006, 70(4):1061-1095.
7. Border W.A., Noble N.A. Transforming growth factor (β) in tissue fibrosis. New England Journal of Medicine 1994, 331(19):1286-1292.
8. Callewaere C., Banisadr G., Rostene W., Parsadaniantz S.M. Chemokines and chemokine receptors in the brain: implication in neuroendocrine regulation. Journal of Molecular Endocrinology 2007, 38:355-363.
9. Chen Y., Chen J., Dong J., Liu W. Antifibrotic effect of interferon gamma in silicosis model of rat. Toxicology Letters 2005, 55(3):353-360.
10. Choi D.E., Jeong J.Y., Lim B.J., Lee K.W., Shin Y.T., Na K.R. Pretreatment with darbepoetin attenuates renal injury in a rat model of cisplatin-induced nephrotoxicity. Korean Journal of Internal Medicine 2009, 24(3):238-246.
11. Cingolani O.H., Yang X.P., Liu Y.H., Villanueva M., Rhaleb N.E., Carretero O.A. Reduction of cardiac fibrosis decreases systolic performance without affecting diastolic function in hypertensive rats. Hypertension 2004, 43:1067-1073.
12. Daniel C., Takabatake Y., Mizui M., Isaka Y., Kawashi H., Rupprecht H., Imai E., Hugo C. Antisense oligonucleotides against thrombospondin-1 inhibit activation of TGF-beta in fibrotic renal disease in the rat in vivo. American Journal of Pathology 2003, 63:1185-1192.
13. Deshmane S.L., Kremlev S., Amini S., Sawaya B.E. Monocyte chemoattractant protein-1 (MCP-1): an overview. Journal of Interferon & Cytokine Research 2009, 29(6):313-326.
14. Guigon M., Bonnet D., Lemoine F.M., Kobari L., Permentier C., Mary J.Y., Najman A. Inhibition of human bone marrow progenitors by the synthetic tetrapeptide AcSDKP. Experimental Hematology 1990, 18:1112-1115.
15. Gupta S., Barrett T., Whitmarsh A.J., Cavanagh J., Sluss H.K., Dérijard B., Davis R.J. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO Journal 1996, 15:2760-2770.
16. He S., Liu X., Yang Y., Huang W., Xu S., Yang S., Zhang X., Roberts M.S. Mechanisms of transforming growth factor beta/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts. British Journal of Dermatology 2009, 162(3):538-546.
17. Ji W.J., Zhou X., Zeng S., Wang S.X. Attenuation of silica-induced pulmonary fibroblasts proliferation by taurine and niacin in vitro. Experimental Lung Research 2009, 35(3):198-209.
18. Kanasaki K., Koya D., Sugimoto T., Isono M., Kashiwagi A., Haneda M. N-acetyl-seryl-aspartyl-lysyl-prolineinhibits TGF-β-mediated plasminogen activator inhibitor-1 expression via inhibition of smad pathway in human mesangial Cells. Journal of the American Society of Nephrology 2003, 14:863-872.
19. Khalil N., Xu Y.D., O'Connor R., Duronio V. Proliferation of pulmonary interstitial fibroblasts is mediated by transforming growth factor-beta1-induced release of extracellular fibroblast growth factor-2 and phosphorylation of p38 MAPK and JNK. The Journal of Biological Chemistry 2005, 280(52):43000-43009.
20. Lenfant M., Wdzieczak-Bakala J., Guittet E., Prome J.C., Sotty D., Frindel E. Inhibitor of hematopoietic pluripotent stem cell proliferation: purification and determination of its structure. Proceedings of the National Academy of Sciences of the United States of America 1989, 86:779-782.
21. Li Q., Yan J., Zhang L., Chen P. Antifibrotic effects of N-acetyl-seryl-aspartyl-lysyl-proline mediated by the regulation of MCP-1 and ED-1 expression on rats with silicosis. Wei Sheng Yan Jiu 2008, 37(6):666-670.
22. Lin C.X., Rhaleb N.E., Yang X.P., Liao T.D., D'Ambrosio M.A., Carretero O.A. Prevention of aortic fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in angiotensin II-induced hypertension. American Journal of Physiology-Heart and Circulatory Physiology 2008, 295:1253-1261.
23. Maria A.C., Liao T.D., Yang X.P., Yang J.J., Carretero O.A. Decreased endogenous levels of Ac-SDKP promote organ fibrosis. Hypertension 2007, 50:130-136.
24. Mazars A., Tournigand C., Mollat P., Prunier C., Ferrand N., Bourgeade M.F., Gespach C., Atfi A. Differential roles of JNK AND Smad2 signaling pathways in the inhibition of c-Myc-induced cell death by TGF-β. Oncology 2000, 19:1277-1287.
25. Miyazono K. TGF-β signaling pathway by smad proteins. Cytokine & Growth Factor Reviews 2000, 11:15-22.
26. Moustakas A., Heldin C.H. Non-Smad TGF-beta signals. Journal of Cell Science 2005, 118(Pt 16):3573-3584.
27. Noguchi K., Kitanaka C., Yamana H., Kokubu A., Mochizuki T., Kuchino Y. Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase. The Journal of Biological Chemistry 1999, 274(46):32580-32587.
28. Olbrück H., Seemayer N.H., Voss B., Wilhelm M. Supernatants from quartz dust treated human macrophages stimulate cell proliferation of different human lung cells as well as collagen-synthesis of human diploid lung fibroblasts in vitro. Toxicology Letters 1998, 96-97:85-95.
29. Peng H., Carretero O.A., Brigstock D.R., Oja-Tebbe N., Rhaleb N.E. Ac-SDKP reverses cardiac fibrosis in rats with renovascular hypertension. Hypertension 2003, 42:1164-1170.
30. Peretz A., Checkoway H., Kaufman J.D., Trajber I., Lerman Y. Silica, silicosis, and lung cancer. Israel Medical Association Journal 2006, 8(2):114-118.
31. Pittet J.F., Griffiths M.J., Geiser T., Kaminski N., Dalton S.L., Huang X., Brown L.A., Gotwals P.J., Koteliansky V.E., Matthay M.A., Sheppard D. TGF-β is a critical mediator of acute lung injury. Journal of Clinical Investigation 2001, 107:1537-1544.
32. Pradelles P., Frobert Y., Créminon C., Ivonine H., Frindel E. Distribution of a negative regulator of haematopoietic stem cell proliferation (AcSDKP) and thymosin-4 in mouse tissues. FEBS Letters 1991, 289:171-175.
33. Reiser K.M., Hesterberg T.W., Haschek W.M., Last J.A. Experimental Silicosis I. Acute effects of intratracheally instilled quartz on collagen metabolism and morphologic characteristics of rat lungs. American Journal of Pathology 1982, 107(2):176-185.
34. Reiser K.M., Haschek W.M., Hesterberg T.W., Last J.A. Experimental silicosis II. Long-term effects of intratracheally instilled quartz on collagen metabolism and morphologic characteristics of rat lungs. American Journal of Pathology 1983, 110(1):30-40.
35. Sharma U., Rhaleb N.E., Pokharel S., Harding P., Rasoul S., Peng H., Carretero O.A. Novel anti-inflammatory mechanisms of n-acetyl-ser-asp-lys-pro in hypertension-induced target organ damage. American Journal of Physiology-Heart and Circulatory Physiology 2008, 294(3):H1226-H1232.
36. Thakur S.A., Beamer C.A., Migliaccio C.T., Holian A. Critical role of MARCO in crystalline silica-induced pulmonary inflammation. Toxicological Science 2009, 108(2):462-471.
37. Wang X., Chen Y., Lv L., Chen J. Silencing CD36 gene expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the rat. Respiratory Research 2009, 10:36-44.
38. Wang X.H., Hao X.H., Zhao J., Ma X.B., Zhu L., Sun Y. Effect of SiO(2) on expression of platelet derived growth factor in human silicotic alveolar macrophages and human embryonic lung fibroblasts. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2009, 27(4):218-221.
39. Silicosis. WHO Fact Sheet No. 238 2000, WHO Health Organization, WHO, Geneva, Switzerland.
40. Yan J.B., Zhang L.J., Li Q. Anti-fibrotic effect of n-acetyl-seryl-aspartyl-lysyl-proline in lung of rat with silicosis. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2008, 26(7):401-405.
41. Yang F., Yang X.P., Liu Y.H., Xu J., Cingolani O., Rhaleb N.E., Carretero O.A. Ac-SDKP reverses inflammation and fibrosis in rats with heart failure after myocardial infarction. Hypertension 2004, 43:229-236.
42. Yucesoy B., Vallyathan V., Landsittel D.P., Sharp D.S., Weston A., Burleson G.R., Simeonova P., McKinstry M., Luster M.I. Association of tumor necrosis factor-alpha and interleukin-1 gene polymorphisms with silicosis. Toxicology and Applied Pharmacology 2001, 172(1):75-82.
43. Zhai R., Ge X., Li H., Tang Z., Liao R., Kleinjans J. Differentces in cellular and inflammatory cytokine profiles in the bronchoalveolar lavage fliud in Bagassisis and silicosis. American Journal of Industrial Medicine 2004, 46:338-344.
44. Zhang Y.E. Non-Smad pathway in TGF-β signaling. Cell Research 2009, 19(1):128-139.
45. Zhuo J.L., Carretero O.A., Peng H., Li X.C., Regoli D., Neugebauer W., Rhaleb1 N.E. Characterization and localization of Ac-SDKP receptor binding sites using 125I-labeled Hpp-Aca-SDKP in rat cardiac fibroblasts. American Journal of Physiology-Heart and Circulatory Physiology 2007, 292(2):H984-H993.