-
1
-
-
0038056326
-
Improved in planta expression of the human islet autoantigen glutamic acid decarboxylase (GAD65)
-
Avesani L, Falorni A, Tornielli GB, Marusic C, Porceddu A, Polverari A, Faleri C, Calcinaro F, Pezzotti M. Improved in planta expression of the human islet autoantigen glutamic acid decarboxylase (GAD65). Transgenic Res. 2003, 12:203-212.
-
(2003)
Transgenic Res.
, vol.12
, pp. 203-212
-
-
Avesani, L.1
Falorni, A.2
Tornielli, G.B.3
Marusic, C.4
Porceddu, A.5
Polverari, A.6
Faleri, C.7
Calcinaro, F.8
Pezzotti, M.9
-
2
-
-
34147126714
-
Stability of potato Virus X expression vectors is related to insert size: implications for replication models and risk assessment
-
Avesani L, Marconi G, Morandini F, Albertini E, Bruschetta M, Bortesi L, Pezzotti M, Porceddu A. Stability of potato Virus X expression vectors is related to insert size: implications for replication models and risk assessment. Transgenic Res. 2007, 16:587-597.
-
(2007)
Transgenic Res.
, vol.16
, pp. 587-597
-
-
Avesani, L.1
Marconi, G.2
Morandini, F.3
Albertini, E.4
Bruschetta, M.5
Bortesi, L.6
Pezzotti, M.7
Porceddu, A.8
-
3
-
-
47249103823
-
Anchorage to the cytosolic face of the ER membrane: a new strategy to stabilize a cytosolic recombinant antigen in plants
-
Barbante A, Irons S, Hawes C, Frigerio L, Vitale A, Pedrazzini E. Anchorage to the cytosolic face of the ER membrane: a new strategy to stabilize a cytosolic recombinant antigen in plants. Plant Biotechnol. J. 2008, 6:560-575.
-
(2008)
Plant Biotechnol. J.
, vol.6
, pp. 560-575
-
-
Barbante, A.1
Irons, S.2
Hawes, C.3
Frigerio, L.4
Vitale, A.5
Pedrazzini, E.6
-
4
-
-
54349106722
-
Plant molecular farming: opportunities and challenges
-
Basaran P, Rodriguez-Cerezo E. Plant molecular farming: opportunities and challenges. Crit. Rev. Biotechnol. 2008, 28:153-172.
-
(2008)
Crit. Rev. Biotechnol.
, vol.28
, pp. 153-172
-
-
Basaran, P.1
Rodriguez-Cerezo, E.2
-
5
-
-
0027203970
-
A plant glutamate decarboxylase containing a calmodulin binding domain. Cloning, sequence and functional analysis
-
Baum G, Chen Y, Arazi T, Takatsuji H, Fromm H. A plant glutamate decarboxylase containing a calmodulin binding domain. Cloning, sequence and functional analysis. J. Biol. Chem. 1993, 268:19610-19617.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19610-19617
-
-
Baum, G.1
Chen, Y.2
Arazi, T.3
Takatsuji, H.4
Fromm, H.5
-
6
-
-
0030014203
-
Calmodulin binding to glutamate decarboxylase is required for regulation of glutamate and GABA metabolism and normal development in plants
-
Baum G, Lev-Yadun S, Fridmann Y, Arazi T, Katsnelson H, Zik M, Fromm H. Calmodulin binding to glutamate decarboxylase is required for regulation of glutamate and GABA metabolism and normal development in plants. EMBO J. 1996, 15:2988-2996.
-
(1996)
EMBO J.
, vol.15
, pp. 2988-2996
-
-
Baum, G.1
Lev-Yadun, S.2
Fridmann, Y.3
Arazi, T.4
Katsnelson, H.5
Zik, M.6
Fromm, H.7
-
7
-
-
64949134655
-
A novel mechanism for GABA synthesis and packaging into synaptic vesicles
-
Buddhala C, Hsu CC, Wu JY. A novel mechanism for GABA synthesis and packaging into synaptic vesicles. Neurochem. Int. 2009, 55:9-12.
-
(2009)
Neurochem. Int.
, vol.55
, pp. 9-12
-
-
Buddhala, C.1
Hsu, C.C.2
Wu, J.Y.3
-
8
-
-
0041465717
-
Crystal structure and functional analysis of Escherichia coli glutamate decarboxylase
-
Capitani G, De Biase D, Aurizi C, Gut H, Bossa F, Grutter MG. Crystal structure and functional analysis of Escherichia coli glutamate decarboxylase. EMBO J. 2003, 22:4027-4037.
-
(2003)
EMBO J.
, vol.22
, pp. 4027-4037
-
-
Capitani, G.1
De Biase, D.2
Aurizi, C.3
Gut, H.4
Bossa, F.5
Grutter, M.G.6
-
9
-
-
65549122095
-
Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function
-
Daniell H, Ruiz G, Denes B, Sandberg L, Langridge W. Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function. BMC Biotechnol. 2009, 3:9-33.
-
(2009)
BMC Biotechnol.
, vol.3
, pp. 9-33
-
-
Daniell, H.1
Ruiz, G.2
Denes, B.3
Sandberg, L.4
Langridge, W.5
-
10
-
-
33747141725
-
Foreign protein degradation and instability in plants and plant tissue cultures
-
Doran PM. Foreign protein degradation and instability in plants and plant tissue cultures. Trends Biotechnol. 2006, 24:426-432.
-
(2006)
Trends Biotechnol.
, vol.24
, pp. 426-432
-
-
Doran, P.M.1
-
11
-
-
0028820248
-
Radioimmunoassay for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands
-
Falorni A, Örtqvist E, Persson B, Lernmark Å Radioimmunoassay for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands. J. Immunol. Methods 1995, 186:89-99.
-
(1995)
J. Immunol. Methods
, vol.186
, pp. 89-99
-
-
Falorni, A.1
Örtqvist, E.2
Persson, B.3
Lernmark, T.4
-
12
-
-
0028103135
-
Distribution of xylosylation and fucosylation in the plant Golgi apparatus
-
Fitchette-Lainè AC, Gomord V, Chekkafi A, Faye L. Distribution of xylosylation and fucosylation in the plant Golgi apparatus. Plant J. 1994, 5:673-682.
-
(1994)
Plant J.
, vol.5
, pp. 673-682
-
-
Fitchette-Lainè, A.C.1
Gomord, V.2
Chekkafi, A.3
Faye, L.4
-
13
-
-
70349232046
-
Protein domains involved in assembly in the endoplasmic reticulum promote vacuolar delivery when fused to secretory GFP, indicating a protein quality control pathway for degradation in the plant vacuole
-
Foresti O, De Marchis F, de Virgilio M, Klein EM, Arcioni S, Bellucci M, Vitale A. Protein domains involved in assembly in the endoplasmic reticulum promote vacuolar delivery when fused to secretory GFP, indicating a protein quality control pathway for degradation in the plant vacuole. Mol. Plant 2008, 1:1067-1076.
-
(2008)
Mol. Plant
, vol.1
, pp. 1067-1076
-
-
Foresti, O.1
De Marchis, F.2
de Virgilio, M.3
Klein, E.M.4
Arcioni, S.5
Bellucci, M.6
Vitale, A.7
-
14
-
-
0034997285
-
Influence of KDEL on the fate of trimeric or assembly-defective phaseolin: selective use of an alternative route to vacuoles
-
Frigerio L, Pastres A, Prada A, Vitale A. Influence of KDEL on the fate of trimeric or assembly-defective phaseolin: selective use of an alternative route to vacuoles. Plant Cell 2001, 13:1109-1126.
-
(2001)
Plant Cell
, vol.13
, pp. 1109-1126
-
-
Frigerio, L.1
Pastres, A.2
Prada, A.3
Vitale, A.4
-
15
-
-
76549198972
-
Pathologic anatomy of the pancreas in the juvenile diabetes mellitus
-
Gepts W. Pathologic anatomy of the pancreas in the juvenile diabetes mellitus. Diabetes 1965, 14:619-633.
-
(1965)
Diabetes
, vol.14
, pp. 619-633
-
-
Gepts, W.1
-
16
-
-
33745752814
-
Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
-
Gut H, Pennacchietti E, John RA, Bossa F, Capitani G, De Biase D, Grutter MG. Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB. EMBO J. 2006, 25:2643-2651.
-
(2006)
EMBO J.
, vol.25
, pp. 2643-2651
-
-
Gut, H.1
Pennacchietti, E.2
John, R.A.3
Bossa, F.4
Capitani, G.5
De Biase, D.6
Grutter, M.G.7
-
17
-
-
0035910379
-
Site-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding
-
Hampe CS, Hammerle LP, Falorni A, Robertson J, Lernmark A. Site-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding. FEBS Lett. 2001, 488:185-189.
-
(2001)
FEBS Lett.
, vol.488
, pp. 185-189
-
-
Hampe, C.S.1
Hammerle, L.P.2
Falorni, A.3
Robertson, J.4
Lernmark, A.5
-
18
-
-
0022550680
-
Analysis of Agrobacterium tumefaciens virulence mutants in leaf discs
-
Horsch RB, Klee HJ, Stachel S, Winans SC, Nester EW, Rogers SG, Fraley RT. Analysis of Agrobacterium tumefaciens virulence mutants in leaf discs. Proc. Natl Acad. Sci. USA 1986, 83:2571-2575.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 2571-2575
-
-
Horsch, R.B.1
Klee, H.J.2
Stachel, S.3
Winans, S.C.4
Nester, E.W.5
Rogers, S.G.6
Fraley, R.T.7
-
19
-
-
0141706699
-
The production of recombinant pharmaceutical proteins in plants
-
Ma JKC, Drake PMW, Christou P. The production of recombinant pharmaceutical proteins in plants. Nat. Rev. Gen. 2003, 4:794-805.
-
(2003)
Nat. Rev. Gen.
, vol.4
, pp. 794-805
-
-
Ma, J.K.C.1
Drake, P.M.W.2
Christou, P.3
-
20
-
-
1842732158
-
Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4
-
Ma S, Huang Y, Yin Z, Menassa R, Brandle JE, Jevnikar AM. Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4. Proc. Natl Acad. Sci. USA 2004, 15:5680-5685.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.15
, pp. 5680-5685
-
-
Ma, S.1
Huang, Y.2
Yin, Z.3
Menassa, R.4
Brandle, J.E.5
Jevnikar, A.M.6
-
21
-
-
23744514106
-
Molecular farming for new drugs and vaccines
-
Ma JKC, Barros E, Bock R, Christou P, Dale PJ, Dix PJ, Fischer R, Irwin J, Mahoney R, Pezzotti M, Schillberg S, Sparrow P, Stoger E, Twyman RM. Molecular farming for new drugs and vaccines. EMBO Rep. 2005a, 6:593-599.
-
(2005)
EMBO Rep.
, vol.6
, pp. 593-599
-
-
Ma, J.K.C.1
Barros, E.2
Bock, R.3
Christou, P.4
Dale, P.J.5
Dix, P.J.6
Fischer, R.7
Irwin, J.8
Mahoney, R.9
Pezzotti, M.10
Schillberg, S.11
Sparrow, P.12
Stoger, E.13
Twyman, R.M.14
-
22
-
-
28244473326
-
Plant-derived pharmaceuticals-the road forward
-
Ma JKC, Chikwamba R, Sparrow P, Fischer R, Mahoney R, Twyman R. Plant-derived pharmaceuticals-the road forward. Trends Plant Sci. 2005b, 10:580-585.
-
(2005)
Trends Plant Sci.
, vol.10
, pp. 580-585
-
-
Ma, J.K.C.1
Chikwamba, R.2
Sparrow, P.3
Fischer, R.4
Mahoney, R.5
Twyman, R.6
-
23
-
-
16544387639
-
Zeolin: a new recombinant storage protein constructed using maize γ-zein and bean phaseolin
-
Mainieri D, Rossi M, Archinti M, Bellucci M, DeMarchis F, Vavassori S, Pompa A, Arcioni S, Vitale A. Zeolin: a new recombinant storage protein constructed using maize γ-zein and bean phaseolin. Plant Physiol. 2004, 136:3447-3456.
-
(2004)
Plant Physiol.
, vol.136
, pp. 3447-3456
-
-
Mainieri, D.1
Rossi, M.2
Archinti, M.3
Bellucci, M.4
DeMarchis, F.5
Vavassori, S.6
Pompa, A.7
Arcioni, S.8
Vitale, A.9
-
24
-
-
33847788546
-
Expression, intracellular targeting and purification of HIV Nef variants in tobacco cells
-
Marusic C, Nuttall J, Buriani G, Lico C, Lombardi R, Baschieri S, Benvenuto E, Frigerio L. Expression, intracellular targeting and purification of HIV Nef variants in tobacco cells. BMC Biotechnol. 2007, 26:7-12.
-
(2007)
BMC Biotechnol.
, vol.26
, pp. 7-12
-
-
Marusic, C.1
Nuttall, J.2
Buriani, G.3
Lico, C.4
Lombardi, R.5
Baschieri, S.6
Benvenuto, E.7
Frigerio, L.8
-
25
-
-
43149096666
-
The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum
-
Nakatsukasa K, Brodsky JL. The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum. Traffic 2008, 9:861-870.
-
(2008)
Traffic
, vol.9
, pp. 861-870
-
-
Nakatsukasa, K.1
Brodsky, J.L.2
-
26
-
-
36249022750
-
Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp
-
Okuda-Shimizu Y, Hendershot LM. Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp. Mol. Cell 2007, 28:544-554.
-
(2007)
Mol. Cell
, vol.28
, pp. 544-554
-
-
Okuda-Shimizu, Y.1
Hendershot, L.M.2
-
27
-
-
0028139847
-
Binding of BiP to an assembly-defective protein in plant cells
-
Pedrazzini E, Giovinazzo G, Bollini R, Ceriotti A, Vitale A. Binding of BiP to an assembly-defective protein in plant cells. Plant J. 1994, 5:103-110.
-
(1994)
Plant J.
, vol.5
, pp. 103-110
-
-
Pedrazzini, E.1
Giovinazzo, G.2
Bollini, R.3
Ceriotti, A.4
Vitale, A.5
-
28
-
-
0031251943
-
Protein quality control along the route to the plant vacuole
-
Pedrazzini E, Giovinazzo G, Bielli A, de Virgilio M, Frigerio L, Pesca M, Faoro F, Bollini R, Ceriotti A, Vitale A. Protein quality control along the route to the plant vacuole. Plant Cell 1997, 9:1869-1880.
-
(1997)
Plant Cell
, vol.9
, pp. 1869-1880
-
-
Pedrazzini, E.1
Giovinazzo, G.2
Bielli, A.3
de Virgilio, M.4
Frigerio, L.5
Pesca, M.6
Faoro, F.7
Bollini, R.8
Ceriotti, A.9
Vitale, A.10
-
29
-
-
0033452018
-
Transgenic plants expressing human glutamic acid decarboxylase (GAD65) a major autoantigen in insulin-dependent diabetes mellitus
-
Porceddu A, Falorni A, Ferradini N, Cosentino A, Calcinaro F, Faleri C, Cresti M, Lorenzetti F, Brunetti P, Pezzotti M. Transgenic plants expressing human glutamic acid decarboxylase (GAD65) a major autoantigen in insulin-dependent diabetes mellitus. Mol. Breed. 1999, 5:553-560.
-
(1999)
Mol. Breed.
, vol.5
, pp. 553-560
-
-
Porceddu, A.1
Falorni, A.2
Ferradini, N.3
Cosentino, A.4
Calcinaro, F.5
Faleri, C.6
Cresti, M.7
Lorenzetti, F.8
Brunetti, P.9
Pezzotti, M.10
-
30
-
-
44949267094
-
Metabolism, enzymology and possible roles of 4-aminobutyrate in higher plants
-
Satyanarayan V, Nair PM. Metabolism, enzymology and possible roles of 4-aminobutyrate in higher plants. Phytochemistry 1990, 29:367-375.
-
(1990)
Phytochemistry
, vol.29
, pp. 367-375
-
-
Satyanarayan, V.1
Nair, P.M.2
-
31
-
-
0030087974
-
The C-terminal KDEL sequence increases the expression level of a single-chain antibody designed to be targeted to both the cytosol and the secretory pathway in transgenic tobacco
-
Schouten A, Roosien J, van Engelen FA, de Jong GA, Borst-Vrenssen AW, Zilverentant JF, Bosch D, Stiekema WJ, Gommers FJ, Schots A, Bakker J. The C-terminal KDEL sequence increases the expression level of a single-chain antibody designed to be targeted to both the cytosol and the secretory pathway in transgenic tobacco. Plant Mol. Biol. 1996, 30:781-793.
-
(1996)
Plant Mol. Biol.
, vol.30
, pp. 781-793
-
-
Schouten, A.1
Roosien, J.2
van Engelen, F.A.3
de Jong, G.A.4
Borst-Vrenssen, A.W.5
Zilverentant, J.F.6
Bosch, D.7
Stiekema, W.J.8
Gommers, F.J.9
Schots, A.10
Bakker, J.11
-
32
-
-
0030060208
-
Activation of a recombinant petunia glutamate decarboxylase by calcium/calmodulin or by a monoclonal antibody which recognises the calmodulin-binding domain
-
Snedden WA, Koutsia N, Baum G, Fromm H. Activation of a recombinant petunia glutamate decarboxylase by calcium/calmodulin or by a monoclonal antibody which recognises the calmodulin-binding domain. J. Biol. Chem. 1996, 271:4148-4153.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4148-4153
-
-
Snedden, W.A.1
Koutsia, N.2
Baum, G.3
Fromm, H.4
-
34
-
-
46849111804
-
The human immunodeficiency virus antigen Nef forms protein bodies in leaves of transgenic tobacco when fused to zeolin
-
de Virgilio M, De Marchis F, Bellucci M, Mainieri D, Rossi M, Benvenuto E, Arcioni S, Vitale A. The human immunodeficiency virus antigen Nef forms protein bodies in leaves of transgenic tobacco when fused to zeolin. J. Exp. Bot. 2008, 59:2815-2829.
-
(2008)
J. Exp. Bot.
, vol.59
, pp. 2815-2829
-
-
de Virgilio, M.1
De Marchis, F.2
Bellucci, M.3
Mainieri, D.4
Rossi, M.5
Benvenuto, E.6
Arcioni, S.7
Vitale, A.8
-
35
-
-
51849097747
-
Endoplasmic reticulum quality control and the unfolded protein response: insights from plants
-
Vitale A, Boston RS. Endoplasmic reticulum quality control and the unfolded protein response: insights from plants. Traffic 2008, 9:1581-1588.
-
(2008)
Traffic
, vol.9
, pp. 1581-1588
-
-
Vitale, A.1
Boston, R.S.2
-
36
-
-
0021274996
-
Transient N-acetyl-glucosamine in the biosynthesis of phytohemagglutin: attachment in the Golgi apparatus and removal in protein bodies
-
Vitale A, Chrispeels MJ. Transient N-acetyl-glucosamine in the biosynthesis of phytohemagglutin: attachment in the Golgi apparatus and removal in protein bodies. J. Cell Biol. 1984, 99:133-140.
-
(1984)
J. Cell Biol.
, vol.99
, pp. 133-140
-
-
Vitale, A.1
Chrispeels, M.J.2
-
37
-
-
24144490427
-
Recombinant pharmaceuticals from plants: the plant endomembrane system as bioreactor
-
Vitale A, Pedrazzini E. Recombinant pharmaceuticals from plants: the plant endomembrane system as bioreactor. Mol. Interv. 2005, 5:216-225.
-
(2005)
Mol. Interv.
, vol.5
, pp. 216-225
-
-
Vitale, A.1
Pedrazzini, E.2
-
38
-
-
0026834063
-
Vicilin with carboxy-terminal KDEL is retained in the endoplasmic reticulum and accumulates to high levels in the leaves of transgenic plants
-
Wandelt CI, Khan MRI, Craig S, Schroeder HE, Spencer D, Higgins TJV. Vicilin with carboxy-terminal KDEL is retained in the endoplasmic reticulum and accumulates to high levels in the leaves of transgenic plants. Plant J. 1992, 2:181-192.
-
(1992)
Plant J.
, vol.2
, pp. 181-192
-
-
Wandelt, C.I.1
Khan, M.R.I.2
Craig, S.3
Schroeder, H.E.4
Spencer, D.5
Higgins, T.J.V.6
-
39
-
-
58249116675
-
A novel expression platform for the production of diabetes-associated autoantigen human glutamic acid decarboxylase (hGAD65)
-
Wang X, Brandsma M, Tremblay R, Maxwell D, Jevnikar AM, Huner N, Ma S. A novel expression platform for the production of diabetes-associated autoantigen human glutamic acid decarboxylase (hGAD65). BMC Biotechnol. 2008, 8:87.
-
(2008)
BMC Biotechnol.
, vol.8
, pp. 87
-
-
Wang, X.1
Brandsma, M.2
Tremblay, R.3
Maxwell, D.4
Jevnikar, A.M.5
Huner, N.6
Ma, S.7
-
40
-
-
0038487228
-
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquinated polypeptide segments and polyubiquitin chains
-
Ye Y, Meyer HH, Rapoport TA. Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquinated polypeptide segments and polyubiquitin chains. J. Cell Biol. 2003, 162:71-84.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 71-84
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
41
-
-
0031106443
-
The rapid determination of γ-aminobutyric acid
-
Zhang G, Bown AW. The rapid determination of γ-aminobutyric acid. Phytochemistry 1997, 44:1007-1009.
-
(1997)
Phytochemistry
, vol.44
, pp. 1007-1009
-
-
Zhang, G.1
Bown, A.W.2
|