Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer

Cancer Genetics and Cytogenetics

Volumn 201, Issue 2, 2010, Pages 128-132

  Pehlivan, Sacide ^a   Artac, Mehmet ^b   Sever, Tugce ^a   Bozcuk, Hakan ^c   Kilincarslan, Can ^a   Pehlivan, Mustafa ^a  

^a GAZIANTEP UNIVERSITY   (Turkey)

^b SELCUK UNIVERSITY   (Turkey)

^c AKDENIZ UNIVERSITY FACULTY OF MEDICINE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH ASSOCIATED PROTEIN KINASE; DEATH ASSOCIATED PROTEIN KINASE 1; K RAS PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; ONCOPROTEIN; PROTEIN HIC1; PROTEIN P16; SECRETED FRIZZLED RELATED PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE REGULATION; CLINICAL ARTICLE; CODON; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; MALE; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METHYLATION; SEX DIFFERENCE;

EID: 77955243498     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2010.05.019     Document Type: Article

References (36)

1. Potter J.D., Slattery M.L., Bostick R.M., Gapstur S.M. Colon cancer: a review of the epidemiology. Epidemiol Rev 1993, 15:499-545.
2. Samowitz W.S., Slattery M.L., Sweeney C., Herrick J., Wolff R.K., Albertsen H. APC mutations and other genetic and epigenetic changes in colon cancer. Mol Cancer Res 2007, 5:165-170.
3. Rashid A., Shen L., Morris J.S., Issa J.P., Hamilton S.R. CpG island methylation in colorectal adenomas. Am J Pathol 2001, 159:1129-1135.
4. Abou-Zeid A.A., Khafagy W., Marzouk D.M., Alaa A., Mostafa I., Ela M.A. Colorectal cancer in Egypt. Dis Colon Rectum 2002, 45:1255-1260.
5. Adekunle O.O., Ajao G.O. Colorectal cancer in adolescent Nigerians. Scand J Gastroenterol 1986, 124:183-186.
6. Chan A.O., Soliman A.S., Zhang Q., Rashid A., Bedeir A., Houlihan P.S., et al. Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries. Clin Cancer Res 2005, 11:8281-8287.
7. Whelan S.L., Ferlay J. Cancer incidence in five continents. Age-specific and standardized incidence rates. IARC Sci PubI 1992, 120:178-861.
8. Dajani Y.F., Zayid I., Malatjalian D.A., Kamal M.F. Colorectal cancer in Jordan and Nova Scotia: a comparative epidemiologic and histopathologic study. Cancer 1980, 46:420-428.
9. Ellidokuz E., Kundak I., Akpinar H., Okan A., Bektaser C., Fuzun M., et al. Kolorektap polip ve kanser lokalizasyonu arasindaki iliski. Kocatepe Ti{dotless}p Derg 2003, 4:49-53.
10. Sweeney C., Boucher K.M., Samowitz W.S., Wolff R.K., Albertsen H., Curtin K., et al. Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors. Genes Chromosomes Cancer 2009, 48:1-9.
11. Xu X.L., Yu J., Zhang H.Y., Sun M.H., Gu J., Du X., Shi D.R., et al. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol 2004, 10:3441-3454.
12. Latham K.E. X chromosome imprinting and inactivation in the early mammalian embryo. Trends Genet 1996, 12:134-138.
13. Issa J.P., Ottaviano Y.L., Celano P., Hamilton S.R., Davidson N.E., Baylin S.B. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 1994, 7:536-540.
14. Goto T., Mizukami H., Shirahata A., Sakata M., Saito M., Ishibashi K., et al. Aberrant methylation of the p16 gene is frequently detected in advanced colorectal cancer. Anticancer Res 2009, 29:275-277.
15. Chen S.P., Chiu S.C., Wu C.C., Lin S.Z., Kang J.C., Chen Y.L., Lin P.C., et al. The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients. Genet Test Mol Biomarkers 2009, 13:67-71.
16. Kane M.F., Loda M., Gaida G.M., Lipman J., Mishra R., Goldman H., et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997, 57:808-811.
17. Artac M., Pehlivan S., Akcan S., Pehlivan M., Gelen T., Itirli G., et al. The role of microsatellite instability to predict clinical benefit from irinotecan-based regimens in metastatic colorectal cancer. Turkish J Cancer 2008, 38:49-56.
18. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988, 16:1215.
19. Willett W.C., Stampfer M.J., Colditz G.A., Rosner B.A., Speizer F.E. Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med 1990, 323. 1664-2.
20. Nystrom M., Mutanen M. Diet and epigenetics in colon cancer. World J Gastroenterol 2009, 15:257-263.
21. Andreyev H.J., Norman A.R., Cunningham D., Oates J.R., Clarke P.A. Kirsten ras mutations in patients with colorectal cancer: the multicenter '" RASCAL" ' study. J Natl Cancer Inst 1998, 90:675-684.
22. Breivik J., Meling G.I., Spurkland A., Rognum T.O., Gaudernack G. K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location. Br J Cancer 1994, 69:367-371.
23. Samowitz W.S., Holden J.A., Curtin K., Edwards S.L., Walker A.R., Lin H.A., et al. Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer. Am J Pathol 2001, 158:1517-1524.
24. Akkiprik M., Celikel C.A., Dusunceli F., Sonmez O., Gulluoglu B.M., Sav A., Ozer A. Relationship between overexpression of ras p21 oncoprotein and K-ras codon 12 and 13 mutations in Turkish colorectal cancer patients. Turk J Gastroenterol 2008, 19:22-27.
25. Krakowczyk L., Strzelczyk J.K., Adamek B., Zalewska-Ziob M., Arendt J., Półtorak S., et al. Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa. Med Sci Monit 2008, 14:219-225.
26. de Vogel S., Weijenberg M.P., Herman J.G., Wouters K.A.D., de Goeij A.F.P.M., van den Brandt P.A., et al. MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events. Annal Oncol 2009, 20:1216-1222.
27. Menigatti M., Truninger K., Gebbers J.O., Marbet U., Marra G., Schar P. Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters. Oncogene 2009, 28:899-909.
28. Huang Z., Li L., Wang J. Hypermethylation of SFRP2 as a potential marker for stool-based detection of colorectal cancer and precancerous lesions. Dig Dis Sci 2007, 52:2287-2291.
29. Oberwalder M., Zitt M., Wöntner C., Fiegl H., Goebel G., Zitt M., et al. SFRP2 methylation in fecal DNA-a marker for colorectal polyps. Int J Colorectal Dis 2008, 23:15-19.
30. Wang D.R., Tang D. Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening. World J Gastroenterol 2008, 14:524-531.
31. Lin Y., Stevens C., Harrison B., Pathuri S., Amin E., Hupp T.R. The alternative splice variant of DAPK-1, s-DAPK-1, induces proteasome-independent DAPK-1 destabilization. Mol Cell Biochem 2009, 328:101-107.
32. Qian J., Yao D.M., Lin J., Wang Y.L., Han L.X., Xu W.R., Wu C.Y. Methylation of DAPK1 promoter: frequent but not an adverse prognostic factor in myelodysplastic syndrome. Int J Lab Hematol 2009, Jan 2. [Epub ahead of print].
33. Zhang J., Martins C.R., Fansler Z.B., Roemer K.L., Kincaid E.A., Gustafson K.S., et al. DNA methylation in anal intraepithelial lesions and anal squamous cell carcinoma. Clin Cancer Res 2005, 11:6544-6549.
34. Worthley D.L., Whitehall V.L., Buttenshaw R.L., Irahara N., Greco S.A., Ramsnes I., et al. DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. Oncogene 2010, 29:1653-1662.
35. Nosho K., Kure S., Irahara N., Shima K., Baba Y., Spiegelman D., et al. A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers. Gastroenterol 2009, 137:1609-1620.
36. Kim Y.H., Kakar S., Cun L., Deng G., Kim Y.S. Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps. Int J Cancer 2008, 123:2587-2593.