Anti-obesity and hypolipidemic effects of ethanolic extract from alpinia officinarum hance (Zingiberaceae) in rats fed high-fat diet

Journal of Medicinal Food

Volumn 13, Issue 4, 2010, Pages 785-791

  Xia, Dao Zong ^a   Yu, Xin Fen ^b   Wang, Hui Ming ^a   Ren, Qi Ya ^a   Chen, Bing Mei ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b HANGZHOU CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Alpinia officinarum Hance; anti obesity; high fat diet; rats

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPINIA OFFICINARUM EXTRACT; ANTIOBESITY AGENT; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHENOL DERIVATIVE; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY FAT DISTRIBUTION; BODY WEIGHT; CHEMICAL COMPOSITION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDIDYMIS; EPIDIDYMIS FAT; FOOD INTAKE; LIPID DIET; LIPID LIVER LEVEL; LIVER; MALE; NONHUMAN; OBESITY; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; TREATMENT OUTCOME; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; ZINGIBERACEAE;

ADIPOSE TISSUE; ALPINIA; ANIMALS; CHOLESTEROL; DIETARY FATS; DISEASE MODELS, ANIMAL; ETHANOL; HUMANS; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; MALE; OBESITY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES;

ALPINIA OFFICINARUM; RATTUS; ZINGIBERACEAE;

EID: 77955219505     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2009.1235     Document Type: Article

References (23)

1. Elangbam CS: Review paper: Current strategies in the development of anti-obesity drugs and their safety concerns. Vet Pathol 2009;46:10-24.
2. Ahn J, Lee H, Kim S, Park J, Ha T: The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways. Biochem Biophys Res Commun 2008;373:545-549.
3. Shrestha S, Bhattarai BR, Lee KH, Cho H: Mono-and disalicylic acid derivatives: PTP1B inhibitors as potential anti-obesity drugs. Bioorg Med Chem 2007;15:6535-6548.
4. Oh KS, Ryu SY, Lee S, Seo HW, Oh BK, Kim YD, Lee BH: Melanin- concentrating hormone-1 receptor antagonism and anti-obesity effects of ethanolic extract from Morus alba leaves in diet-induced obese rats. J Ethnopharmacol 2009;122:216-220.
5. Garrison R, Chambliss WG: Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-54.
6. Oh KS, Ryu SY, Lee S, et al.: Melanin-concentrating hormone-1 receptor antagonism and anti-obesity effects of ethanolic extract from Morus alba leaves in diet-induced obese mice. J Ethno-pharmacol 2009;122:216-220.
7. Kim SO, Yun SJ, Lee EH: The water extract of adlay seed (Coix lachrymajobi var. mayuen) exhibits anti-obesity effects through neuroendocrine modulation. Am J Chin Med 2007;35:297-308.
8. An N, Zhang HW, Xu LZ, Yang SL, Zou ZM: New dia-rylheptanoids from the rhizome of Alpinia officinarum HANCE. Food Chem 2010;119:513-517.
9. Huang H, Wu D, Tian WX, Ma XF, Wu XD: Antimicrobial effect by extracts of rhizome of Alpinia officinarum Hance. may relate to its inhibition of b-ketoacyl-ACP reductase. J Enzyme Inhib Med Chem 2008;23:362-368.
10. Shin D, Kinoshit K, Koyama K, Takahashi K: Antiemetic principles of Alpinia officinarum. J Nat Prod 2002;65:1315-1318.
11. An N, Zou ZM, Tian Z, Luo XZ, Yang SL, Xu LZ: Dia-rylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity. Fitoterapia 2008;79:27-31.
12. Yasukawa K, Sun Y, Kitanaka S, Tomizawa N, Miura M, Motohashi S: Inhibitory effect of the rhizomes of Alpinia offici-narum on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin. J Nat Med 2008;62:374-378.
13. Matsuda H, Ando S, Kato T, Morikawa T, Yoshikawa M: Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity. Bioorg Med Chem 2006;14:138-142.
14. Shin JE, Han MJ, Kim DH: 3-Methylethergalangin isolated from Alpinia officinarum inhibits pancreatic lipase. Biol Pharm Bull 2003;26:854-857.
15. Shin JE, Han MJ, Song MC, Baek NI, Kim DH: 5-Hydroxy-7-(49-hydroxy-39- methoxyphenyl)-1-phenyl-3-heptanone: a pancreatic lipase inhibitor isolated from Alpinia officinarum. Biol Pharm Bull 2004;27:138-140.
16. Jimoh FO, Sofidiya MO, Afolayan AJ: Antioxidant properties of the methanol extracts from the leaves of Paullinia pinnata. J Med Food 2007;10:707-711.
17. Piccolella S, Fiorentino A, Pacifico S, D'Abrosca B, Uzzo P, Monaco P: Antioxidant properties of sour cherries (Prunus cerasus L.): role of colorless phytochemicals from the metha-nolic extract of ripe fruits. J Agric Food Chem 2008;56:1928-1935.
18. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502.
19. Woo MN, Bok SH, Lee MK, et al.: Anti-obesity and hypoli-pidemic effects of a proprietary herb and fiber combination (S&S PWH) in rats fed high-fat diets. J Med Food 2008;11: 169-178.
20. Choi I, Kim Y, Park Y, Seog H, Choi H: Anti-obesity activities of fermented soygerm isoflavones by Bifidobacterium breve. Biofactors 2007;29:105-112.
21. Lin JK, Lin-Shiau SY: Mechanisms of hypolipidemic and anti-obesity effects of tea and tea polyphenols. Mol Nutr Food Res 2006;50:211-217.
22. Yang JY, Lee SJ, Park HW, Cha YS: Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl=6J rats fed a high-fat diet. J Med Food 2006;9:459-467.
23. McKay DL, Blumberg JB: Cranberries (Vaccinium macro-carpon) and cardiovascular disease risk factors. Nutr Rev 2007;65:490-502.