Role of chloride channels in nitric oxide-induced rat hippocampal neuronal apoptosis in vitro

Neural Regeneration Research

Volumn 5, Issue 9, 2010, Pages 690-694

  Chang, Quanzhong ^a   Zhang, Shuling ^a   Yin, Jinbao ^a  

^a ZUNYI MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral ischemia; Chloride channel; Hippocampal neuron; Neural regeneration; Nitric oxide; Rats

Indexed keywords

4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CASPASE 3; CHLORIDE CHANNEL; LINSIDOMINE; NITRIC OXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL NUCLEUS; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REPRESSION; HIPPOCAMPUS; IN VITRO STUDY; NERVE CELL LESION; NONHUMAN; PROTEIN FUNCTION; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

EID: 77955200337     PISSN: 16735374     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1673-5374.2010.09.009     Document Type: Article

References (28)

1. Jóźwiak Z, Marczak A.The role of ion channels in apoptosis. Postepy Biochem. 2006;52(4):373-382.
2. Lang F, Lang KS, Wieder T, et al. Cation channels, cell volume and the death of an erythrocyte. Pflugers Arch. 2003;447(2): 121-125.
3. Cheng G, Ramanathan A, Shao Z, et al. Chloride channel expression and functional diversity in the immune cells of allergic diseases. Curr Mol Med. 2008;8(5):401-407.
4. Cheng G, Shao Z, Chaudhari B, et al. Involvement of chloride channels in TGF-beta1-induced apoptosis of human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2007;293(5): L1339-1347.
5. Maeno E, Ishizaki Y, Kanaseki T, et al. Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc Natl Acad Sci U S A. 2000;97(17):9487-9492.
6. Thinnes FP, Walter G, Hellmann KP, et al. Gadolinium as an opener of the outwardly rectifying Cl(-) channel (ORCC). Is there relevance for cystic fibrosis therapy? Pflugers Arch. 2001;443 Suppl 1:S111-116.
7. Nietsch HH, Roe MW, Fiekers JF, et al. Activation of potassium and chloride channels by tumor necrosis factor alpha. Role in liver cell death. J Biol Chem. 2000;275(27):20556-20561.
8. Malekova L, Tomaskova J, Novakova M, et al. Inhibitory effect of DIDS, NPPB, and phloretin on intracellular chloride channels. Pflugers Arch. 2007;455(2):349-357.
9. Wei L, Xiao AY, Jin C, et al. Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons. Pflugers Arch. 2004;448(3):325-334.
10. Chang QZ, Hu DH, Gao TM. Protective effects of chloride channel blocker on hippocampal neuronal apoptosis induced by N-methyi-D-aspartate cultured in vitro. Zhongguo Linchuang Kangfu. 2005;9(48):64-67.
11. Inoue H, Okada Y. Roles of volume-sensitive chloride channel in excitotoxic neuronal injury. J Neurosci. 2007;27(6):1445-1455.
12. Small DL, Tauskela J, Xia Z. Role for chloride but not potassium channels in apoptosis in primary rat cortical cultures. Neurosci Lett. 2002;334(2):95-98.
13. The Ministry of Science and Technology of the People's Republic of China. Guidance Suggestions for the Care and Use of Laboratory Animals. 2006-09-30.
14. Churn SB, Sombati S, Jakoi ER, et al. Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons. Proc Natl Acad Sci U S A. 2000;97(10):5604-5609.
15. Concannon CG, Ward MW, Bonner HP, et al. NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner. J Neurochem. 2008;105(3):891-903.
16. Sieuwerts AM, Klijn JG, Peters HA, et al. The MTT tetrazolium salt assay scrutinized: how to use this assay reliably to measure metabolic activity of cell cultures in vitro for the assessment of growth characteristics, IC50-values and cell survival. Eur J Clin Chem Clin Biochem. 1995;33(11):813-823.
17. Zhu LX, Liu J, Xie YH, et al. Expression of hepatitis C virus envelope protein 2 induces apoptosis in cultured mammalian cells. World J Gastroenterol. 2004;10(20):2972-2978.
18. Chang QZ, Zhang SL, Yin JB, et al. The protective effects of chloride channel blockers on the cultured hippocampal neuronal apoptosis induced by NO in rats. Zhongguo Yaolixue Tongbao. 2009;25(9):1197-1200.
19. Kirsch DG, Doseff A, Chau BN, et al. Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. J Biol Chem. 1999;274(30):21155-21161.
20. Petrov VI, Pisarev VB, Ponomarev EA, et al. Variability of neuronal damage and proportion of activities of NO synthase isoforms during cerebral ischemia/reperfusion in rats. Bull Exp Biol Med. 2007;144(5):657-660.
21. Chen J, Graham SH, Nakayama M, et al. Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia. J Cereb Blood Flow Metab. 1997;17(1): 2-10.
22. Chang QZ, Hu DH, Chen M, et al. Neuroprotection of chloride channel blockers against NMDA-induced apoptosis of cultured rat hippocampal neurons. Nan Fang Yi Ke Da Xue Xue Bao. 2006; 26(2):158-161.
23. O'Reilly N, Xia Z, Fiander H, et al. Disparity between ionic mediators of volume regulation and apoptosis in N1E 115 mouse neuroblastoma cells. Brain Res. 2002;943(2):245-256.
24. Inglefield JR, Schwartz-Bloom RD. Activation of excitatory amino acid receptors in the rat hippocampal slice increases intracellular Cl- and cell volume. J Neurochem. 1998;71(4):1396-1404.
25. Gao MQ, Guo SB, Chen XH, et al. Molecular mechanisms of polypeptide from Chlamys farreri protecting HaCaT cells from apoptosis induced by UVA plus UVB. Acta Pharmacol Sin. 2007; 28(7):1007-1014.
26. Lepple-Wienhues A, Szabò I, Wieland U, et al. Tyrosine kinases open lymphocyte chloride channels. Cell Physiol Biochem. 2000;10(5-6):307-312.
27. Schulz JB, Weller M, Matthews RT, et al. Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia. Cell Death Differ. 1998; 5(10):847-857.
28. Lipton SA, Choi YB, Pan ZH, et al. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature. 1993;364(6438): 626-632.