Cocaine reverses the changes in GABAA subunits and in glutamic acid decarboxylase isoenzymes mRNA expression induced by neonatal 6-hydroxydopamine

Behavioural Pharmacology

Volumn 21, Issue 4, 2010, Pages 343-352

  De Azeredo, Lucas Araújo ^a   Marquardt, André Rosito ^a   Guedes Frazzon, Ana Paula ^a   Tannhauser Barros, Helena Maria ^a  

^a UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

Author keywords

attention deficit hyperactivity disorder; cocaine; GABAA subunits; GAD isoenzymes; hippocampus; open field; prefrontal cortex; rat; striatum

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA4; 4 AMINOBUTYRIC ACID A RECEPTOR BETA1; COCAINE; GLUTAMATE DECARBOXYLASE; ISOENZYME; MESSENGER RNA; OXIDOPAMINE; ADRENERGIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; EVALUATION; GENE EXPRESSION; HIPPOCAMPUS; HYPERACTIVITY; LOCOMOTION; MALE; NONHUMAN; OPEN FIELD TEST; PREFRONTAL CORTEX; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYMOLOGY; HYPERKINESIA; METABOLISM; NEWBORN; PSYCHOLOGY; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; COCAINE; CORPUS STRIATUM; GLUTAMATE DECARBOXYLASE; HIPPOCAMPUS; HYPERKINESIS; ISOENZYMES; MALE; OXIDOPAMINE; PREFRONTAL CORTEX; RATS; RATS, WISTAR; RECEPTORS, GABA-A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYMPATHOLYTICS;

EID: 77955173738     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32833b33af     Document Type: Article

References (59)

1. Alonso S, Minty A, Bourlet Y, Buckingham M (1986). Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates. J Mol Evol 23:11-22.
2. Archer T, Danysz W, Friedriksson A, Jonsson G, Luthman J, Sundström E, et al. (1988). Neonatal 6-hydroxydopamine-induced dopamine depletions: motor activity and performance in maze learning. Pharmacol Biochem Behav 31:357-364.
3. Arnsten AF (2006). Fundamentals of attention-deficit/hyperactivity disorder: circuits and pathways. J Clin Psychiatry 8:7-12.
4. Augustyniak PN, Kourrich S, Rezazadeh SM, Stewart J, Arvanitogiannis A (2006). Differential behavioral and neurochemical effects of cocaine after early exposure to methylphenidate in an animal model of attention deficit hyperactivity disorder. Behav Brain Res 167:379-382.
5. Backes E, Hemby SE (2003). Discrete cell gene profiling of ventral tegmental dopamine neurons after acute and chronic cocaine self-administration. J Pharmacol Exp Ther 307:450-459.
6. Balster RL, Woolverton WL (1982). Intravenous buspirone self-administration in rhesus monkeys. J Clin Psychiatry 43:34-39.
7. Barros HM, Miczek KA (1996). Withdrawal from oral cocaine in rats: ultrasonic vocalizations and tactile startle. Psychopharmacology (Berl) 125:379-384.
8. Biederman J, Faraone SV (2005). Attention-deficit hyperactivity disorder. Lancet 366:237-248.
9. Bukstein O (2008). Substance use disorders in adolescents with attention-deficit/hyperactivity disorder. Adolesc Med State Art Rev 19:242-253.
10. Cameron DL, Williams JT (1994). Cocaine inhibits GABA release in the VTA through endogenous 5-HT. J Neurosci 14:6763-6767.
11. Carta AR, Moreno CC, Cadoni C, Tronci E, Di Chiara G (2008). Long-term increase in GAD67 mRNA expression in the central amygdala of rats sensitized by drugs and stress. Eur J Neurosci 27:1220-1230.
12. Chadha A, Dawson LG, Jenner PG, Duty S (2000). Effect of unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway on GABA(A) receptor subunit gene expression in the rodent basal ganglia and thalamus. Neuroscience 95:119-126.
13. Chen Q, Lee TH, Wetsel WC, Sun QA, Liu Y, Davidson C, et al. (2007). Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor alpha2 subunit expression, and PKC zeta activity. Biochem Biophys Res Commun 356:733-738.
14. Choleris E, Thomas AW, Kavaliers M, Prato FS (2001). A detailed ethological analysis of the mouse open field test: effects of diazepam, chlordiazepoxide and an extremely low frequency pulsed magnetic field. Neurosci Biobehav Rev 25:235-260.
15. Erinoff L, MacPhail RC, Heller A, Seiden LS (1979). Age-dependent effects of 6-hydroxydopamine on locomotor activity in the rat. Brain Res 164:195-205.
16. Fone KC, Nutt DJ (2005). Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder. Curr Opin Pharmacol 5:87-93.
17. Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG (1999). Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283:397-401.
18. Guardiola A, Saibro L, Coronel A, Rotta NT, Barros HMT (1993). Effects of imipramine on hyperactivity produced by neonatal treatment with 6-hydroxydopamine. Med Sci Res 21:179-180.
19. Heffner TG, Seiden LS (1982). Possible involvement of serotonergic neurons in the reduction of locomotor hyperactivity caused by amphetamine in neonatal rats depleted of brain dopamine. Brain Res 244:81-90.
20. Jayaram P, Steketee JD (2005). Effects of cocaine-induced behavioural sensitization on GABA transmission within rat medial prefrontal cortex. Eur J Neurosci 21:2035-2039.
21. Johanson CE, Fischman MW (1989). The pharmacology of cocaine related to its abuse. Pharmacol Rev 41:3-52.
22. Kalivas KW (2007). Neurobiology of cocaine addiction: implications for new pharmacotherapy. Am J Addict 16:71-78.
23. Kollins SH (2003). Comparing the abuse potential of methylphenidate versus other stimulants: a review of available evidence and relevance to the ADHD patient. J Clin Psychiatry 11:14-18.
24. Laprade N, Soghomonian JJ (1999). Gene expression of the GAD67 and GAD65 isoforms of glutamate decarboxylase is differentially altered in subpopulations of striatal neurons in adult rats lesioned with 6-OHDA as neonates. Synapse 33:36-48.
25. Liang J, Suryanarayanan A, Abriam A, Snyder B, Olsen RW, Spigelman I (2007). Mechanisms of reversible GABAA receptor plasticity after ethanol intoxication. J Neurosci 27:12367-12377.
26. Lindefors N, Hurd YL, O'Connor WT, Brene S, Persson H, Ungerstedt U (1992). Amphetamine regulation of acetylcholine and gamma-aminobutyric acid in nucleus accumbens. Neuroscience 48:439-448.
27. Luthman J, Fredriksson A, Lewander T, Jonsson G, Archer T (1989). Effects of d-amphetamine and methylphenidate on hyperactivity produced by neonatal 6-hydroxydopamine treatment. Psychopharmacology (Berl) 99: 550-557.
28. Luthman J, Lindqvist E, Ogren SO (1995). Hyperactivity in neonatally dopamine-lesioned rats requires residual activity in mesolimbic dopamine neurons. Pharmacol Biochem Behav 51:159-163.
29. Luthman J, Bassen M, Friedriksson A, Archer T (1997). Functional changes induced by neonatal cerebral 6-hydroxydopamine treatment: effects of doses levels on behavioural parameters. Behav Brain Res 82:213-221.
30. Marquardt AR, Ortiz-Lemos L, Lucion AB, Barros HM (2004). Influence of handling or aversive stimulation during rats' neonatal or adolescence periods on oral cocaine self-administration and cocaine withdrawal. Behav Pharmacol 15:403-412.
31. Molina-Holgado E, Dewar KM, Grondin L, Van Gelder NM, Reader TA (1993a). Changes of amino acid and monoamine levels after neonatal 6-hydroxydo-pamine denervation in rat basal ganglia, substantia nigra, and Raphe nuclei. J Neurosci Res 35:409-418.
32. Molina-Holgado E, Dewar KM, Grondin L, Van Gelder NM, Reader TA (1993b). Amino acid levels and gamma-aminobutyric acidA receptors in rat neostriatum, cortex, and thalamus after neonatal 6-hydroxydopamine lesion. J Neurochem 60:936-945.
33. Molina-Holgado E, Van Gelder NM, Dewar KM, Reader TA (1995). Dopamine receptor alterations correlate with increased GABA levels in adult rat neostriatum: effects of a neonatal 6-hydroxydopamine denervation. Neuro-chem Int 27:443-451.
34. Mora F, Segovia G, Del Arco A (2008). Glutamate-dopamine-GABA interactions in the aging basal ganglia. Brain Res Rev 58:340-353.
35. Morris HV, Dawson GR, Reynolds DS, Atack JR, Rosahl TW, Stephens DN (2008). Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine. Pharmacol Biochem Behav 90:9-18.
36. Nin MS, Salles FB, Azeredo LA, Frazon AP, Gomez R, Barros HM (2008). Antidepressant effect and changes of GABAA receptor gamma2 subunit mRNA after hippocampal administration of allopregnanolone in rats. J Psychopharmacol 22:477-485.
37. Pirker S, Schwarzer C, Wieselthaler A, Sieghart W, Sperk G (2000). GABAA receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. Neuroscience 4:815-850.
38. Pliszka SR, McCracken JT, Maas JW (1996). Catecholamines in attention-deficit hyperactivity disorder: current perspectives. J Am Acad Child Adolesc Psychiat 35:264-272.
39. Podkletnova I, Raevsky V, Alho H (1996). Reduction of GABAergic transmission and alterations in behavior after 6-OHDA treatment of rats. Brain Res Dev Brain Res 94:197-204.
40. Podkletnova I, Mäkelä R, Korpi ER, Lüddens H, Helen P, Alho H (2000). Neonatal 6-hydroxydopamine treatment affects GABA(A) receptor subunit expression in the frontal cortex but not the hippocampus of rats during postnatal development. Dev Neurosc 22:296-302.
41. Prut L, Belzung C (2003). The open field as a paradigm to measure the effects of drugs on anxiety-like behaviours: a review. Eur J Pharmacol 463:3-33.
42. Russell VA, de Villiers A, Sagvolden T, Lamm M, Taljaard J (1995). Altered dopaminergic function in the prefrontal cortex, nucleus accumbens and caudate-putamen of an animal model of attention hyperactivity disorder. Behav Brain Res 94:163-171.
43. Schubiner H, Tzelepis A, Milberger S, Lockhart N, Kruger M, Kelley BJ (2000). Prevalence of attention-deficit/hyperactivity disorder and conduct disorder among substance abusers. J Clin Psychiatry 61:244-251.
44. Shaywitz BA, Klopper JH, Yager RD, Gordon JW (1976a). Paradoxical response to amphetamine in developing rats treated with 6-hydroxidopamine. Nature 261:153-155.
45. Shaywitz BA, Yager RD, Klopper JH (1976b). Seletive brain dopamine depletion in developing rats: an experimental model of minimal brain dysfunction. Science 191:305-308.
46. Shaywitz BA, Klopper JH, Gordon JW (1978). Methylphenidate in 6-hydoxydo-pamine-treated developing rat pups. Effects on activity and maze performance. Arch Neurol 3:463-469.
47. Smith JE, Koves TR, Co C (2003). Brain neurotransmitter turnover rates during rat intravenous cocaine self-administration. Neuroscience 117:461-475.
48. Soghomonian JJ, Martin DL (1998). Two isoforms of glutamate decarboxylase: why? Trends Pharmacol Sci 19:500-505.
49. Sorg BA, Guminski BJ, Hooks MS, Kalivas PW (1995). Cocaine alters glutamic acid decarboxylase differentially in the nucleus accumbens core and shell. Brain Res Mol Brain Res 29:381-386.
50. Souza MF,Toniazo VM, Frazzon AP, Barros HM (2009). Influence of progesterone on GAD65 and GAD67 mRNA expression in the dorsolateral striatum and prefrontal cortex of female rats repeatedly treated with cocaine. Braz J Med Biol Res 42:1068-1075.
51. Spencer TJ, Biederman J, Mick E (2007). Attention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. J Pediatr Psychol 32:631-642.
52. Sullivan RM, Brake WG (2003). What the rodent prefrontal cortex can teach us about attention-deficit/hyperactivity disorder: the critical role of early developmental events on prefrontal function. Behav Brain Res 146:43-55.
53. Suzuki T, Abe S, Yamaguchi M, Baba A, Hori T, Shiraishi H, et al. (2000). Effects of cocaine administration on receptor binding and subunits mRNA of GABA(A)-benzodiazepine receptor complexes. Synapse 38:198-215.
54. Tang XC, McFarland K, Cagle S, Kalivas PW (2005). Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum. J Neurosci 25:4512-4520.
55. Van Dyke C, Jatlow P, Ungerer J, Barash PG, Byck R (1978). Oral cocaine: plasma concentrations and central effects. Science 200:211-213.
56. Volkow ND, Wang GJ, Fowler JS, Logan J, Franceschi D, Maynard L, et al. (2002b). Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: therapeutic implications. Synapse 43:181-187.
57. Yamaguchi M, Suzuki T, Abe S, Baba A, Ito T, Okado N (2000). Time-course effects of a single administration of cocaine on receptor binding and subunit mRNAs of GABA(A) receptors. Brain Res Mol Brain Res 81:155-163.
58. Yamaguchi M, Suzuki T, Abe S, Baba A, Hori T, Okado N (2002). Repeated cocaine administration increases GABA(B(1) subunit mRNA in rat brain. Synapse 43:175-180.
59. Zhang X, Lee TH, Xiong X, Chen Q, Davidson C, Wetsel WC, et al. (2007). Methamphetamine induces long-term changes in GABAA receptor a2 subunit and GAD67 expression. Biochem Biophys Res Commun 356:733-738.