Comparing the abuse potential of methylphenidate versus other stimulants: A review of available evidence and relevance to the ADHD patient

Journal of Clinical Psychiatry

Volumn 64, Issue SUPPL. 11, 2003, Pages 14-18

  Kollins, Scott H ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; COCAINE; DEXAMPHETAMINE; DEXTROAMP; DOPAMINE TRANSPORTER; LYSERGIDE; METHYLPHENIDATE; MORPHINE; PSYCHOSTIMULANT AGENT; PSYCHOTROPIC AGENT;

ATTENTION DEFICIT DISORDER; BEHAVIOR; CONFERENCE PAPER; DRUG ABUSE; DRUG DEPENDENCE; DRUG DISTRIBUTION; DRUG SELF ADMINISTRATION; DRUG UPTAKE; HUMAN; NEUROPHARMACOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REINFORCEMENT;

ADULT; ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; COCAINE; DEXTROAMPHETAMINE; HUMANS; METHYLPHENIDATE; REINFORCEMENT (PSYCHOLOGY); SUBSTANCE-RELATED DISORDERS;

EID: 0141540759     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (18)

1. Breggin P. Questioning the treatment for ADHD [letter]. Science 2001;291:595
2. Diller LH. The run on Ritalin: attention deficit disorder and stimulant treatment in the 1990s. Hastings Cent Rep 1996;26:12-18
3. Greenhill LL, Pliszka S, Dulcan MK, et al. Practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults. J Am Acad Child Adolesc Psychiatry 2002;41:26S-49S
4. Carey WB, Diller LH. Concerns about Ritalin [letter]. J Pediatr 2001;139:338-340
5. Bukstein OG, Brent DA, Kaminer Y. Comorbidity of substance abuse and other psychiatric disorders in adolescents. Am J Psychiatry 1989;146:1131-1141
6. Diagnosis and treatment of attention deficit hyperactivity disorder. NIH Consensus Statement Online. Nov 16-18, 1998;16:1-37. Available at: http://consensus.nih.gov/cons/110/110_intro.htm. Accessed Jan 24, 2003
7. Fischman MW, Mello NK, eds. Testing for Abuse Liability of Drugs in Humans. National Institute on Drug Abuse Research Monograph Series 92. US Dept of Health and Human Services publication (ADM) 89-1613. Washington, DC: US Government Printing Office; 1989
8. Kollins SH, MacDonald EK, Rush CR. Assessing the abuse potential of methylphenidate in nonhuman and human subjects: a review. Pharmacol Biochem Behav 2001;68:611-627
9. Martin WR, Sloan JW, Sapira JD, et al. Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man. Clin Pharmacol Ther 1971;12:245-258
10. Balster RL, Bigelow GE. Guidelines and methodological reviews concerning drug abuse liability assessment. Drug Alcohol Depend 2003;70:S13-S40
11. Roehrs T, Papineau K, Rosenthal L, et al. Sleepiness and the reinforcing and subjective effects of methylphenidate. Exp Clin Psychopharmacol 1999;7:145-150
12. Volkow ND, Ding Y-S, Fowler JS, et al. Is methylphenidate like cocaine? studies on their pharmacokinetics and distribution in the human brain. Arch Gen Psychiatry 1995;52:456-463
13. Volkow ND, Fowler JS, Wang G-J, et al. Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies. Eur Neuropsychopharmacol 2002;12:557-566
14. Volkow ND, Fowler JS, Wang G-J. Imaging studies on the role of dopamine in cocaine reinforcement and addiction in humans. J Psychopharmacol 1999;13:337-345
15. Kollins SH, Rush CR, Pazzaglia PJ, et al. Comparison of acute behavioral effects of sustained-release and immediate-release methylphenidate. Exp Clin Psychopharmacol 1998;6:367-374
16. Volkow ND, Wang GJ, Fowler JS, et al. Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate. Am J Psychiatry 1998;155:1325-1331
17. Krause KH, Dresel SH, Krause J, et al. Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography. Neurosci Lett 2000;285:107-110
18. Dresel S. Krause J, Krause KH, et al. Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment. Eur J Nucl Med 2000;27:1518-1524