Human 21T breast epithelial cell lines mimic breast cancer progression in vivo and in vitro and show stage-specific gene expression patterns

Laboratory Investigation

Volumn 90, Issue 8, 2010, Pages 1247-1258

  Souter, Lesley H ^a,b   Andrews, Joseph D ^a   Zhang, Guihua ^a   Cook, Amy C ^a,b   Postenka, Carl O ^a   Al Katib, Waleed ^a   Leong, Hon S ^a   Rodenhiser, David I ^a,b,c   Chambers, Ann F ^a,b   Tuck, Alan B ^a,b  

^a LONDON REGIONAL CANCER PROGRAM   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c CHILDREN S HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

atypical ductal hyperplasia; breast cancer; ductal carcinoma in situ; expression microarray; invasive mammary carcinoma; tumor progression

Indexed keywords

MATRIGEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CARCINOMA; BREAST EPITHELIUM; BREAST HYPERPLASIA; CANCER CELL CULTURE; CANCER GROWTH; CANCER STAGING; CELL INVASION; CELL MOTILITY; CELL POLARITY; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; EPIGENETICS; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRADUCTAL CARCINOMA; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUDE MOUSE; OBSERVATIONAL STUDY; PRECANCER; PRIORITY JOURNAL;

EID: 77955146162     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2010.97     Document Type: Article

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