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Volumn 12, Issue 15, 2010, Pages 3434-3437

Titanium-mediated spirocyclization reactions of 4-alkylpyridines

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[No Author keywords available]

Indexed keywords


EID: 77955131544     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol1012636     Document Type: Article
Times cited : (13)

References (34)
  • 1
    • 58049221259 scopus 로고    scopus 로고
    • For recent examples of intermolecular nucleophilic additions to activated pyridines, see: McCall, W. S.; Grillo, T. A.; Comins, D. L. J. Org. Chem. 2008, 73, 9744
    • (2008) J. Org. Chem. , vol.73 , pp. 9744
    • McCall, W.S.1    Grillo, T.A.2    Comins, D.L.3
  • 12
    • 63849213807 scopus 로고    scopus 로고
    • For examples of intramolecular nucleophilic additions to pyridines leading to spiro-dihydropyridine products, see: Brice, H.; Clayden, J. Chem. Commun. 2009, 1964
    • (2009) Chem. Commun. , pp. 1964
    • Brice, H.1    Clayden, J.2
  • 28
    • 77955163046 scopus 로고    scopus 로고
    • 4 is the only Lewis acid examined that possesses basic counterions. The presence of isopropoxide also resulted in contamination of 6 with trace amounts of the corresponding isopropyl ester 9a
    • 4 is the only Lewis acid examined that possesses basic counterions. The presence of isopropoxide also resulted in contamination of 6 with trace amounts of the corresponding isopropyl ester 9a.
  • 30
    • 77955135831 scopus 로고    scopus 로고
    • There are only a few reports describing the participation of enamides in metal-catalyzed cycloisomerizations
    • There are only a few reports describing the participation of enamides in metal-catalyzed cycloisomerizations
  • 34
    • 77955132189 scopus 로고    scopus 로고
    • 3 and AgOTf for efficient cycloisomerization. No reaction occurred in the presence of TfOH alone
    • 3 and AgOTf for efficient cycloisomerization. No reaction occurred in the presence of TfOH alone.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.