-
1
-
-
0842268019
-
-
For recent reviews on the stereoselective synthesis of piperidines, see: (a) Buffat, M. G. P. Tetrahedron 2004, 60, 1701-1729.
-
(2004)
Tetrahedron
, vol.60
, pp. 1701-1729
-
-
Buffat, M.G.P.1
-
3
-
-
0037459890
-
-
(c) Weintraub, P. M.; Sabol, J. S.; Kane, J. M.; Borcherding, D. R. Tetrahedron 2003, 59, 2953-2989.
-
(2003)
Tetrahedron
, vol.59
, pp. 2953-2989
-
-
Weintraub, P.M.1
Sabol, J.S.2
Kane, J.M.3
Borcherding, D.R.4
-
4
-
-
31544443516
-
-
For recent examples, see: (a) Ijzendoorn, D. R.; Botman, P. N. M.; Blaauw, R. H. Org. Lett. 2006, 8, 239-242.
-
(2006)
Org. Lett.
, vol.8
, pp. 239-242
-
-
Ijzendoorn, D.R.1
Botman, P.N.M.2
Blaauw, R.H.3
-
8
-
-
4644272647
-
-
(e) Ichikawa, E.; Suzuki, M.; Yabu, K.; Albert, M.; Kanai, M.; Shibasaki, M. J. Am. Chem. Soc. 2004, 126, 11808-11809.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 11808-11809
-
-
Ichikawa, E.1
Suzuki, M.2
Yabu, K.3
Albert, M.4
Kanai, M.5
Shibasaki, M.6
-
9
-
-
2442720188
-
-
(f) Shintani, R.; Tokunaga, N.; Doi, H.; Hayashi, T. J. Am. Chem. Soc. 2004, 126, 6240-6241.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 6240-6241
-
-
Shintani, R.1
Tokunaga, N.2
Doi, H.3
Hayashi, T.4
-
10
-
-
0027285071
-
-
(g) Genisson, Y. Marazano, C.; Das, B. C. J. Org. Chem. 1993, 58, 2052-2057.
-
(1993)
J. Org. Chem.
, vol.58
, pp. 2052-2057
-
-
Genisson, Y.1
Marazano, C.2
Das, B.C.3
-
12
-
-
28844505658
-
-
(b) Charette, A. B.; Mathieu, S.; Martel, J. Org. Lett. 2005, 7, 5401-5404.
-
(2005)
Org. Lett.
, vol.7
, pp. 5401-5404
-
-
Charette, A.B.1
Mathieu, S.2
Martel, J.3
-
14
-
-
15444361998
-
-
(d) Lemire, A.; Beaudoin, D.; Grenon, M.; Charette, A. B. J. Org. Chem. 2005, 70, 2368-2371.
-
(2005)
J. Org. Chem.
, vol.70
, pp. 2368-2371
-
-
Lemire, A.1
Beaudoin, D.2
Grenon, M.3
Charette, A.B.4
-
16
-
-
6444238793
-
-
(f) Lemire, A.; Grenon, M.; Pourashraf, M.; Charette, A. B. Org. Lett. 2004, 6, 3517-3520.
-
(2004)
Org. Lett.
, vol.6
, pp. 3517-3520
-
-
Lemire, A.1
Grenon, M.2
Pourashraf, M.3
Charette, A.B.4
-
18
-
-
0035965734
-
-
(h) Charette, A. B.; Grenon, M.; Lemire, A.; Pourashraf, M.; Martel, J. J. Am. Chem. Soc. 2001, 123, 11829-11830.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 11829-11830
-
-
Charette, A.B.1
Grenon, M.2
Lemire, A.3
Pourashraf, M.4
Martel, J.5
-
19
-
-
33748918629
-
-
U.S. Patent 3,334,104
-
For examples of non-natural 2,5-substituted piperidines of interest, see: (a) Houlihan, W. J. U.S. Patent 3,334,104.
-
-
-
Houlihan, W.J.1
-
20
-
-
33748939306
-
-
German Patent, DE 1 964 441 (in German); U.S. Patent 3,709,677
-
(b) Houlihan, W. J. German Patent, DE 1 964 441 (in German); U.S. Patent 3,709,677.
-
-
-
Houlihan, W.J.1
-
21
-
-
33748929754
-
-
French Patent FR 2 095 399 (in French)
-
(c) Tilles, H. French Patent FR 2 095 399 (in French).
-
-
-
Tilles, H.1
-
22
-
-
33748950687
-
-
(d) Balsamo, A.; Barili, P. L.; Gagliardi, M.; Lapucci, A.; Macchia, B.; Macchia, F.; Bergamaschi, M. Chim. Ind. 1976, 58, 222-222.
-
(1976)
Chim. Ind.
, vol.58
, pp. 222-222
-
-
Balsamo, A.1
Barili, P.L.2
Gagliardi, M.3
Lapucci, A.4
Macchia, B.5
Macchia, F.6
Bergamaschi, M.7
-
23
-
-
0019960821
-
-
(e) Balsamo, A.; Barili, P. L.; Gagliardi, M.; Lapucci, A.; Macchia, B.; Macchia, F.; Bergamaschi, M. Eur. J. Med. Chem. 1982, 17, 285-289.
-
(1982)
Eur. J. Med. Chem.
, vol.17
, pp. 285-289
-
-
Balsamo, A.1
Barili, P.L.2
Gagliardi, M.3
Lapucci, A.4
Macchia, B.5
Macchia, F.6
Bergamaschi, M.7
-
25
-
-
0030936863
-
-
(g) Macchia, B.; Macchia, M.; Martinelli, A.; Martinotti, E.; Orlandini, E.; Romagnoli, F.; Scatizzi, R. Eur. J. Med. Chem. 1997, 32, 231-240.
-
(1997)
Eur. J. Med. Chem.
, vol.32
, pp. 231-240
-
-
Macchia, B.1
Macchia, M.2
Martinelli, A.3
Martinotti, E.4
Orlandini, E.5
Romagnoli, F.6
Scatizzi, R.7
-
26
-
-
33748930496
-
-
World Patent WO 9952907
-
(h) Bright, G. M. World Patent WO 9952907.
-
-
-
Bright, G.M.1
-
27
-
-
0025897584
-
-
For examples of recent synthesis of 2,5-substituted piperidines, see: (a) Gnecco, D.; Marazano, C.; Das, B. C. Chem. Commun. 1991, 625-626.
-
(1991)
Chem. Commun.
, pp. 625-626
-
-
Gnecco, D.1
Marazano, C.2
Das, B.C.3
-
28
-
-
0028796243
-
-
(b) Varea, T.; Dufour, M.; Micouin, L.; Riche, C.; Chiaroni, A.; Quirion, J.-C.; Husson, H.-P. Tetrahedron Lett. 1995, 36, 1035-1038.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 1035-1038
-
-
Varea, T.1
Dufour, M.2
Micouin, L.3
Riche, C.4
Chiaroni, A.5
Quirion, J.-C.6
Husson, H.-P.7
-
29
-
-
0038751918
-
-
(c) Kuethe, J. T.; Brooks, C. A.; Comins, D. L. Org. Lett. 2003, 5, 321-323.
-
(2003)
Org. Lett.
, vol.5
, pp. 321-323
-
-
Kuethe, J.T.1
Brooks, C.A.2
Comins, D.L.3
-
30
-
-
0035906471
-
-
(a) Katayama, S.; Ae, N.; Nagata, R. J. Org. Chem. 2001, 66, 3474-3483.
-
(2001)
J. Org. Chem.
, vol.66
, pp. 3474-3483
-
-
Katayama, S.1
Ae, N.2
Nagata, R.3
-
32
-
-
0035907458
-
-
(c) Papageorgiou, C.; Camenisch, G.; Borer, X. Bioorg. Med. Chem. Lett. 2001, 11, 1549-1552.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 1549-1552
-
-
Papageorgiou, C.1
Camenisch, G.2
Borer, X.3
-
33
-
-
0035825071
-
-
(d) Alvarez, M.; Fernández, D.; Joule, J. A. Tetrahedron Lett. 2001, 42, 315-317.
-
(2001)
Tetrahedron Lett.
, vol.42
, pp. 315-317
-
-
Alvarez, M.1
Fernández, D.2
Joule, J.A.3
-
34
-
-
0035848414
-
-
(e) Nam, G.; Yoon, C. M.; Kim, E.; Rhee, C. K.; Kim, J. H.; Shin, J. H.; Kim, S. H. Bioorg. Med. Chem. Lett. 2001, 11, 611-614.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 611-614
-
-
Nam, G.1
Yoon, C.M.2
Kim, E.3
Rhee, C.K.4
Kim, J.H.5
Shin, J.H.6
Kim, S.H.7
-
36
-
-
0000587717
-
-
(g) Tani, M.; Ikegami, H.; Tashiro, M.; Hiura, T.; Tsukioka, H.; Kaneko, C.; Notoya, T.; Shimizu, M.; Uchida, M.; Aida, Y.; Yokoyama, Y.; Murakami, Y. Heterocycles 1992, 34, 2349-2362.
-
(1992)
Heterocycles
, vol.34
, pp. 2349-2362
-
-
Tani, M.1
Ikegami, H.2
Tashiro, M.3
Hiura, T.4
Tsukioka, H.5
Kaneko, C.6
Notoya, T.7
Shimizu, M.8
Uchida, M.9
Aida, Y.10
Yokoyama, Y.11
Murakami, Y.12
-
37
-
-
0001007478
-
-
(a) Lavilla, R.; Coll, O.; Kumar, R.; Bosch, J. J. Org. Chem. 1998, 63, 2728-2730.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 2728-2730
-
-
Lavilla, R.1
Coll, O.2
Kumar, R.3
Bosch, J.4
-
38
-
-
0032556795
-
-
(b) Lavilla, R.; Kumar, R.; Coll, O.; Masdeu, C.; Bosch, J. Chem. Commun. 1998, 2715-2716.
-
(1998)
Chem. Commun.
, pp. 2715-2716
-
-
Lavilla, R.1
Kumar, R.2
Coll, O.3
Masdeu, C.4
Bosch, J.5
-
39
-
-
12344337506
-
-
(c) Norton Matos, M.; Afonso, C. A. M.; Batey, R. A. Tetrahedron 2005, 61, 1221-1244.
-
(2005)
Tetrahedron
, vol.61
, pp. 1221-1244
-
-
Norton Matos, M.1
Afonso, C.A.M.2
Batey, R.A.3
-
40
-
-
0037146031
-
-
(a) Kirchhoff, J. H.; Netherton, M. R.; Hills, I. D.; Fu, G. C. J. Am. Chem. Soc. 2002, 124, 13662-13663.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 13662-13663
-
-
Kirchhoff, J.H.1
Netherton, M.R.2
Hills, I.D.3
Fu, G.C.4
-
41
-
-
0034600318
-
-
(b) Littke, A. F.; Dai, C.; Fu, G. C. J. Am. Chem. Soc. 2000, 122, 4020-4028.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 4020-4028
-
-
Littke, A.F.1
Dai, C.2
Fu, G.C.3
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