Dendritic cell differentiation with prostaglandin E2 results in selective attenuation of the extracellular signal-related kinase pathway and decreased interleukin-23 production

Immunology

Volumn 131, Issue 1, 2010, Pages 67-76

  Hayashi, Fumie ^a   Yanagawa, Yoshiki ^a,b   Onoé, Kazunori ^a   Iwabuchi, Kazuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

dendritic cells; extracellular signal related kinases 1 2; interleukin 23; prostaglandin E2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 23; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; DINOPROSTONE; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INTERLEUKIN-12; INTERLEUKIN-23; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; SIGNAL TRANSDUCTION;

EID: 77955128373     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2010.03275.x     Document Type: Article

References (43)

1. Steinman R. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 1991 9 : 271 296.
2. Hart DNJ. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 1997 90 : 3245 3287.
3. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998 392 : 245 251.
4. Cyster JG. Chemokines and cell migration in secondary lymphoid organs. Science 1999 286 : 2098 2102.
5. Sallusto F, Lanzavecchia A. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunol Rev 2000 177 : 134 140.
6. Pearce EJ, Kane CM, Sun JR. Regulation of dendritic cell function by pathogen-derived molecules plays a key role in dictating the outcome of the adaptive immune response. Chem Immunol Allergy 2006 90 : 82 90.
7. Goriely S, Neurath MF, Goldman M. How microorganisms tip the balance between interleukin-12 family members. Nat Rev Immunol 2008 8 : 81 6.
8. Goriely S, Goldman M. The interleukin-12 family: new players in transplantation immunity? Am J Transplant 2007 7 : 278 284.
9. + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005 6 : 1123 1132.
10. Park H, Li Z, Yang XO et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005 6 : 1133 1141.
11. Mangan PR, Harrington LE, O'Quinn DB et al. Transforming growth factor-β induces development of the T(H)17 lineage. Nature 2006 441 : 231 234.
12. Bettelli E, Carrier Y, Gao W et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 441 : 235 238.
13. Goetzl EJ, An S, Smith WL. Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases. FASEB J 1995 9 : 1051 1058.
14. Sugimoto Y, Narumiya S. Prostaglandin E receptors. J Biol Chem 2007 282 : 11613 11617.
15. Phipps RP, Stein SH, Roper RL. A new view of prostaglandin-E regulation of the immune response. Immunol Today 1991 12 : 349 352.
16. Harris SG, Padilla J, Koumas L, Ray D, Phipps RP. Prostaglandins as modulators of immunity. Trends Immunol 2002 23 : 144 150.
17. 2 is a major inhibitor of dendritic cell maturation and function in Ixodes scapularis saliva. J Immunol 2007 179 : 1497 1505.
18. 2 induces IL-23 production in bone marrow-derived dendritic cells. FASEB J 2004 18 : 1318 1320. (Pubitemid 39561589)
19. 2 in experimental inflammatory bowel disease is mediated through the IL-23→IL-17 axis. J Immunol 2007 178 : 8138 8147.
20. 2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. J Immunol 2008 181 : 721 735.
21. Inaba K, Inaba M, Romani N, Aya H, Deguchi M, Ikehara S, Muramatsu S, Steinman RM. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 1992 176 : 1693 1702.
22. + regulatory T cells from peripheral Foxp3 precursors. Blood 2007 110 : 4293 4302.
23. Yanagawa Y, Onoé K. Enhanced IL-10 production by TLR4- and TLR2-primed dendritic cells upon TLR restimulation. J Immunol 2007 178 : 6173 6180.
24. Kawai T, Akira S. Pathogen recognition with Toll-like receptors. Curr Opin Immunol 2005 17 : 338 344.
25. Kawai T, Akira S. Signaling to NF-κB by Toll-like receptors. Trends Mol Med 2007 13 : 460 469.
26. Hirata N, Yanagawa Y, Ebihara T et al. Selective synergy in anti-inflammatory cytokine production upon cooperated signaling via TLR4 and TLR2 in murine conventional dendritic cells. Mol Immunol 2008 45 : 2734 2742.
27. Hirata N, Yanagawa Y, Iwabuchi K, Onoé K. Selective regulation of interleukin-10 production via Janus kinase pathway in murine conventional dendritic cells. Cell Immunol 2009 258 : 9 17.
28. H2 hypothesis of T cell-mediated tissue damage. Nat Med 2007 13 : 139 145.
29. H17 cells. Annu Rev Immunol 2009 27 : 485 517.
30. Ferber IA, Brocke S, Taylor-Edwards C et al. Mice with a disrupted IFN-γ gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 1996 156 : 5 7.
31. Vermeire K, Heremans H, Vandeputte M, Huang S, Billiau A, Matthys P. Accelerated collagen-induced arthritis in IFN-γ receptor-deficient mice. J Immunol 1997 158 : 5507 5513. (Pubitemid 127681260)
32. Manoury-Schwartz B, Chiocchia G, Bessis N et al. High susceptibility to collagen-induced arthritis in mice lacking IFN-γ receptors. J Immunol 1997 158 : 5501 5506.
33. 2 in vivo. Dev Immunol 1992 2 : 263 271.
34. 2 induces apoptosis in resting immature and mature human lymphocytes: a c-Myc-dependent and Bcl-2-independent associated pathway. J Pharmacol Exp Ther 1996 277 : 1793 1800.
35. 2 inhibits T-cell-activation-induced apoptosis and Fas-mediated cellular cytotoxicity by blockade of Fas-ligand induction. Eur J Immunol 1999 29 : 2360 2365.
36. 2 on the growth and differentiation of human B lymphocytes activated through their CD40 antigen. J Immunol 1994 152 : 4282 4290.
37. Fukao T, Tanabe M, Terauchi Y et al. PI3K-mediated negative feedback regulation of IL-12 production in DCs. Nat Immunol 2002 3 : 875 881.
38. Puig-Kröger A, Relloso M, Fernández-Capetillo O, Zubiaga A, Silva A, Bernabéu C, Corbí AL. Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells. Blood 2001 98 : 2175 2182.
39. Yanagawa Y, Iijima N, Iwabuchi K, Onoé K. Activation of extracellular signal-related kinase by TNF-α controls the maturation and function of murine dendritic cells. J Leukoc Biol 2002 71 : 125 132.
40. Agrawal S, Agrawal A, Doughty B, Gerwitz A, Blenis J, Van Dyke T, Pulendran B. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J Immunol 2003 171 : 4984 4989.
41. Saccani S, Pantano S, Natoli G. p38-Dependent marking of inflammatory genes for increased NF-κB recruitment. Nat Immunol 2002 3 : 69 75.
42. Re F, Strominger JL. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J Biol Chem 2001 276 : 37692 37699.
43. Hirschfeld M, Ma M, Weis JH, Vogel SN, Weis JJ. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol 2000 165 : 618 622.