메뉴 건너뛰기




Volumn 8, Issue , 2010, Pages

A novel cell-free mitochondrial fusion assay amenable for high-throughput screenings of fusion modulators

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL PROTEIN; NUCLEOTIDE;

EID: 77955099425     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-8-100     Document Type: Article
Times cited : (39)

References (28)
  • 1
    • 56349133547 scopus 로고    scopus 로고
    • Positioning mitochondrial plasticity within cellular signaling cascades
    • 10.1016/j.bbamcr.2008.07.008, 18694785
    • Soubannier V, McBride HM. Positioning mitochondrial plasticity within cellular signaling cascades. Biochim Biophys Acta 2009, 1793(1):154-170. 10.1016/j.bbamcr.2008.07.008, 18694785.
    • (2009) Biochim Biophys Acta , vol.1793 , Issue.1 , pp. 154-170
    • Soubannier, V.1    McBride, H.M.2
  • 2
    • 0025076787 scopus 로고
    • Temperature-sensitive yeast mutants defective in mitochondrial inheritance
    • 10.1083/jcb.111.3.967, 2116285, 2202739
    • McConnell SJ, Stewart LC, Talin A, Yaffe MP. Temperature-sensitive yeast mutants defective in mitochondrial inheritance. J Cell Biol 1990, 111(3):967-976. 10.1083/jcb.111.3.967, 2116285, 2202739.
    • (1990) J Cell Biol , vol.111 , Issue.3 , pp. 967-976
    • McConnell, S.J.1    Stewart, L.C.2    Talin, A.3    Yaffe, M.P.4
  • 3
    • 0036198860 scopus 로고    scopus 로고
    • Genetic Basis of mitochondrial function and morphology in Saccharomyces cerevisiae
    • 10.1091/mbc.01-12-0588, 99603, 11907266
    • Dimmer KS, Fritz S, Fuchs F, Messerschmitt M, Weinbach N, Neupert W, Westermann B. Genetic Basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 2002, 13(3):847-853. 10.1091/mbc.01-12-0588, 99603, 11907266.
    • (2002) Mol Biol Cell , vol.13 , Issue.3 , pp. 847-853
    • Dimmer, K.S.1    Fritz, S.2    Fuchs, F.3    Messerschmitt, M.4    Weinbach, N.5    Neupert, W.6    Westermann, B.7
  • 4
    • 27644467457 scopus 로고    scopus 로고
    • Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae
    • 10.1091/mbc.E05-07-0678, 1266436, 16135527
    • Altmann K, Westermann B. Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 2005, 16(11):5410-5417. 10.1091/mbc.E05-07-0678, 1266436, 16135527.
    • (2005) Mol Biol Cell , vol.16 , Issue.11 , pp. 5410-5417
    • Altmann, K.1    Westermann, B.2
  • 5
    • 4544378532 scopus 로고    scopus 로고
    • Mitochondrial fusion intermediates revealed in vitro
    • 10.1126/science.1100612, 15297626
    • Meeusen S, McCaffery JM, Nunnari J. Mitochondrial fusion intermediates revealed in vitro. Science 2004, 305(5691):1747-1752. 10.1126/science.1100612, 15297626.
    • (2004) Science , vol.305 , Issue.5691 , pp. 1747-1752
    • Meeusen, S.1    McCaffery, J.M.2    Nunnari, J.3
  • 6
    • 33749991592 scopus 로고    scopus 로고
    • Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1
    • 10.1016/j.cell.2006.09.021, 17055438
    • Meeusen S, DeVay R, Block J, Cassidy-Stone A, Wayson S, McCaffery JM, Nunnari J. Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1. Cell 2006, 127(2):383-395. 10.1016/j.cell.2006.09.021, 17055438.
    • (2006) Cell , vol.127 , Issue.2 , pp. 383-395
    • Meeusen, S.1    DeVay, R.2    Block, J.3    Cassidy-Stone, A.4    Wayson, S.5    McCaffery, J.M.6    Nunnari, J.7
  • 7
    • 61449256510 scopus 로고    scopus 로고
    • Mitochondrial outer and inner membrane fusion requires a modified carrier protein
    • 10.1083/jcb.200809099, 2654124, 19237599
    • Hoppins S, Horner J, Song C, McCaffery JM, Nunnari J. Mitochondrial outer and inner membrane fusion requires a modified carrier protein. J Cell Biol 2009, 184(4):569-581. 10.1083/jcb.200809099, 2654124, 19237599.
    • (2009) J Cell Biol , vol.184 , Issue.4 , pp. 569-581
    • Hoppins, S.1    Horner, J.2    Song, C.3    McCaffery, J.M.4    Nunnari, J.5
  • 8
    • 0036906665 scopus 로고    scopus 로고
    • Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins
    • 10.1091/mbc.E02-06-0330, 138638, 12475957
    • Legros F, Lombes A, Frachon P, Rojo M. Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell 2002, 13(12):4343-4354. 10.1091/mbc.E02-06-0330, 138638, 12475957.
    • (2002) Mol Biol Cell , vol.13 , Issue.12 , pp. 4343-4354
    • Legros, F.1    Lombes, A.2    Frachon, P.3    Rojo, M.4
  • 9
    • 21644455319 scopus 로고    scopus 로고
    • Activated Mfn2 signals mitochondrial fusion, interferes with Bax activation and reduces susceptibility to radical induced depolarization
    • 10.1074/jbc.M501599200, 15878861
    • Neuspiel M, Zunino R, Gangaraju S, Rippstein P, McBride HM. Activated Mfn2 signals mitochondrial fusion, interferes with Bax activation and reduces susceptibility to radical induced depolarization. J Biol Chem 2005, 280(26):25060-25070. 10.1074/jbc.M501599200, 15878861.
    • (2005) J Biol Chem , vol.280 , Issue.26 , pp. 25060-25070
    • Neuspiel, M.1    Zunino, R.2    Gangaraju, S.3    Rippstein, P.4    McBride, H.M.5
  • 10
    • 1242307475 scopus 로고    scopus 로고
    • Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis
    • 10.1083/jcb.200309082, 2172000, 14769861
    • Karbowski M, Arnoult D, Chen H, Chan DC, Smith CL, Youle RJ. Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis. J Cell Biol 2004, 164(4):493-499. 10.1083/jcb.200309082, 2172000, 14769861.
    • (2004) J Cell Biol , vol.164 , Issue.4 , pp. 493-499
    • Karbowski, M.1    Arnoult, D.2    Chen, H.3    Chan, D.C.4    Smith, C.L.5    Youle, R.J.6
  • 11
    • 34248225298 scopus 로고    scopus 로고
    • The SUMO protease SENP5 is required to maintain mitochondrial morphology and function
    • 10.1242/jcs.03418, 17341580
    • Zunino R, Schauss A, Rippstein P, Andrade-Navarro M, McBride HM. The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. J Cell Sci 2007, 120(Pt 7):1178-1188. 10.1242/jcs.03418, 17341580.
    • (2007) J Cell Sci , vol.120 , Issue.PART 7 , pp. 1178-1188
    • Zunino, R.1    Schauss, A.2    Rippstein, P.3    Andrade-Navarro, M.4    McBride, H.M.5
  • 12
    • 46449125605 scopus 로고    scopus 로고
    • Membrane fusion
    • 10.1038/nsmb.1451, 2488960, 18618939
    • Wickner W, Schekman R. Membrane fusion. Nat Struct Mol Biol 2008, 15(7):658-664. 10.1038/nsmb.1451, 2488960, 18618939.
    • (2008) Nat Struct Mol Biol , vol.15 , Issue.7 , pp. 658-664
    • Wickner, W.1    Schekman, R.2
  • 13
    • 77951096150 scopus 로고    scopus 로고
    • Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases
    • 10.1093/hmg/ddp326, 2758711, 19808793
    • Chen H, Chan DC. Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases. Hum Mol Genet 2009, 18(R2):R169-176. 10.1093/hmg/ddp326, 2758711, 19808793.
    • (2009) Hum Mol Genet , vol.18 , Issue.R2
    • Chen, H.1    Chan, D.C.2
  • 14
    • 68949116271 scopus 로고    scopus 로고
    • Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes
    • 10.1016/j.biocel.2009.02.004, 19703653
    • Zorzano A, Liesa M, Palacin M. Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetes. Int J Biochem Cell Biol 2009, 41(10):1846-1854. 10.1016/j.biocel.2009.02.004, 19703653.
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.10 , pp. 1846-1854
    • Zorzano, A.1    Liesa, M.2    Palacin, M.3
  • 15
    • 77955416276 scopus 로고    scopus 로고
    • A quantitative assay for mitochondrial fusion using renilla luciferase complementation
    • Huang H, Choi SY, Frohman MA. A quantitative assay for mitochondrial fusion using renilla luciferase complementation. Mitochondrion 2010,
    • (2010) Mitochondrion
    • Huang, H.1    Choi, S.Y.2    Frohman, M.A.3
  • 16
    • 33644861986 scopus 로고    scopus 로고
    • Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions
    • 10.2144/000112036, 16454041
    • Shyu YJ, Liu H, Deng X, Hu CD. Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions. Biotechniques 2006, 40(1):61-66. 10.2144/000112036, 16454041.
    • (2006) Biotechniques , vol.40 , Issue.1 , pp. 61-66
    • Shyu, Y.J.1    Liu, H.2    Deng, X.3    Hu, C.D.4
  • 17
    • 65449167679 scopus 로고    scopus 로고
    • Engineered luciferases for molecular sensing in living cells
    • 10.1016/j.copbio.2009.02.013, 19299118
    • Binkowski B, Fan F, Wood K. Engineered luciferases for molecular sensing in living cells. Curr Opin Biotechnol 2009, 20(1):14-18. 10.1016/j.copbio.2009.02.013, 19299118.
    • (2009) Curr Opin Biotechnol , vol.20 , Issue.1 , pp. 14-18
    • Binkowski, B.1    Fan, F.2    Wood, K.3
  • 18
    • 0027049521 scopus 로고
    • A signal-anchor sequence selective for the mitochondrial outer membrane
    • 10.1083/jcb.119.6.1451, 2289765, 1334957
    • McBride HM, Millar DG, Li JM, Shore GC. A signal-anchor sequence selective for the mitochondrial outer membrane. J Cell Biol 1992, 119(6):1451-1457. 10.1083/jcb.119.6.1451, 2289765, 1334957.
    • (1992) J Cell Biol , vol.119 , Issue.6 , pp. 1451-1457
    • McBride, H.M.1    Millar, D.G.2    Li, J.M.3    Shore, G.C.4
  • 19
    • 68749112707 scopus 로고    scopus 로고
    • Importing mitochondrial proteins: machineries and mechanisms
    • 10.1016/j.cell.2009.08.005, 19703392
    • Chacinska A, Koehler CM, Milenkovic D, Lithgow T, Pfanner N. Importing mitochondrial proteins: machineries and mechanisms. Cell 2009, 138(4):628-644. 10.1016/j.cell.2009.08.005, 19703392.
    • (2009) Cell , vol.138 , Issue.4 , pp. 628-644
    • Chacinska, A.1    Koehler, C.M.2    Milenkovic, D.3    Lithgow, T.4    Pfanner, N.5
  • 20
    • 8944248278 scopus 로고    scopus 로고
    • The human mitochondrial import receptor, hTom20p, prevents a cryptic matrix targeting sequence from gaining access to the protein translocation machinery
    • 10.1083/jcb.134.2.307, 2120874, 8707817
    • McBride HM, Goping IS, Shore GC. The human mitochondrial import receptor, hTom20p, prevents a cryptic matrix targeting sequence from gaining access to the protein translocation machinery. J Cell Biol 1996, 134(2):307-313. 10.1083/jcb.134.2.307, 2120874, 8707817.
    • (1996) J Cell Biol , vol.134 , Issue.2 , pp. 307-313
    • McBride, H.M.1    Goping, I.S.2    Shore, G.C.3
  • 21
    • 0025974686 scopus 로고
    • Rab5 controls early endosome fusion in vitro
    • 10.1016/0092-8674(91)90316-Q, 1900457
    • Gorvel JP, Chavrier P, Zerial M, Gruenberg J. rab5 controls early endosome fusion in vitro. Cell 1991, 64(5):915-925. 10.1016/0092-8674(91)90316-Q, 1900457.
    • (1991) Cell , vol.64 , Issue.5 , pp. 915-925
    • Gorvel, J.P.1    Chavrier, P.2    Zerial, M.3    Gruenberg, J.4
  • 22
    • 0028333056 scopus 로고
    • G-protein ligands inhibit in vitro reactions of vacuole inheritance
    • 10.1083/jcb.126.1.87, 2120106, 8027189
    • Haas A, Conradt B, Wickner W. G-protein ligands inhibit in vitro reactions of vacuole inheritance. J Cell Biol 1994, 126(1):87-97. 10.1083/jcb.126.1.87, 2120106, 8027189.
    • (1994) J Cell Biol , vol.126 , Issue.1 , pp. 87-97
    • Haas, A.1    Conradt, B.2    Wickner, W.3
  • 23
    • 30944446045 scopus 로고    scopus 로고
    • Separate fusion of outer and inner mitochondrial membranes
    • 10.1038/sj.embor.7400488, 1369163, 16113651
    • Malka F, Guillery O, Cifuentes-Diaz C, Guillou E, Belenguer P, Lombes A, Rojo M. Separate fusion of outer and inner mitochondrial membranes. EMBO Rep 2005, 6(9):853-859. 10.1038/sj.embor.7400488, 1369163, 16113651.
    • (2005) EMBO Rep , vol.6 , Issue.9 , pp. 853-859
    • Malka, F.1    Guillery, O.2    Cifuentes-Diaz, C.3    Guillou, E.4    Belenguer, P.5    Lombes, A.6    Rojo, M.7
  • 24
    • 45349094984 scopus 로고    scopus 로고
    • Mitochondrial dynamics and apoptosis
    • 10.1101/gad.1658508, 2732420, 18559474
    • Suen DF, Norris KL, Youle RJ. Mitochondrial dynamics and apoptosis. Genes Dev 2008, 22(12):1577-1590. 10.1101/gad.1658508, 2732420, 18559474.
    • (2008) Genes Dev , vol.22 , Issue.12 , pp. 1577-1590
    • Suen, D.F.1    Norris, K.L.2    Youle, R.J.3
  • 25
    • 34547611925 scopus 로고    scopus 로고
    • Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology
    • 10.1074/jbc.C700083200, 17553808
    • Chang CR, Blackstone C. Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology. J Biol Chem 2007, 282(30):21583-21587. 10.1074/jbc.C700083200, 17553808.
    • (2007) J Biol Chem , vol.282 , Issue.30 , pp. 21583-21587
    • Chang, C.R.1    Blackstone, C.2
  • 26
    • 34848840991 scopus 로고    scopus 로고
    • Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
    • 10.1038/sj.embor.7401062, 2002551, 17721437
    • Cribbs JT, Strack S. Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death. EMBO Rep 2007, 8(10):939-944. 10.1038/sj.embor.7401062, 2002551, 17721437.
    • (2007) EMBO Rep , vol.8 , Issue.10 , pp. 939-944
    • Cribbs, J.T.1    Strack, S.2
  • 28
    • 33845472429 scopus 로고    scopus 로고
    • Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology
    • 10.1073/pnas.0604983103, 1693702, 17116872
    • Jeyaraju DV, Xu L, Letellier MC, Bandaru S, Zunino R, Berg EA, McBride HM, Pellegrini L. Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology. Proc Natl Acad Sci USA 2006, 103(49):18562-18567. 10.1073/pnas.0604983103, 1693702, 17116872.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.49 , pp. 18562-18567
    • Jeyaraju, D.V.1    Xu, L.2    Letellier, M.C.3    Bandaru, S.4    Zunino, R.5    Berg, E.A.6    McBride, H.M.7    Pellegrini, L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.