Inhibition of C6 rat glioma proliferation by [Ru2Cl(Ibp)4] depends on changes in p21, p27, Bax/Bcl2 ratio and mitochondrial membrane potential

Journal of Inorganic Biochemistry

Volumn 104, Issue 9, 2010, Pages 928-935

  Benadiba, Marcel ^a   dos Santos, Renata Rolim Prudente ^a   Silva, Denise de Oliveira ^a   Colquhoun, Alison ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Albumin; Apoptosis; Glioma; Ibuprofen; Mitochondria; Ruthenium

Indexed keywords

CYCLIN D1; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; KU ANTIGEN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P27; PROTEIN P53; RETINOBLASTOMA PROTEIN; RUTHENIUM COMPLEX; TRANSCRIPTION FACTOR E2F1; ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; RUTHENIUM DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; GLIOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; CHEMISTRY; DRUG EFFECTS; FLOW CYTOMETRY; GLIOMA; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

RATTUS;

ANIMALS; ANTINEOPLASTIC AGENTS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DINOPROSTONE; FLOW CYTOMETRY; GLIOMA; MEMBRANE POTENTIAL, MITOCHONDRIAL; RATS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RUTHENIUM COMPOUNDS;

EID: 77955086102     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2010.04.011     Document Type: Article

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