-
1
-
-
16944363984
-
Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation
-
10.1038/ng1297-439, 9398846
-
Carmeliet P, Moons L, Lijnen R, Baes M, Lemaitre V, Tipping P, Drew A, Eeckhout Y, Shapiro S, Lupu F, et al. Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation. Nature Genetics 1997, 17(4):439-444. 10.1038/ng1297-439, 9398846.
-
(1997)
Nature Genetics
, vol.17
, Issue.4
, pp. 439-444
-
-
Carmeliet, P.1
Moons, L.2
Lijnen, R.3
Baes, M.4
Lemaitre, V.5
Tipping, P.6
Drew, A.7
Eeckhout, Y.8
Shapiro, S.9
Lupu, F.10
-
2
-
-
0029031780
-
Steps involved in activation of the complex of pro-matrix metalloproteinase 2 (progelatinase A) and tissue inhibitor of metalloproteinases (TIMP)-2 by 4-aminophenylmercuric acetate
-
1136975, 7772054
-
Itoh Y, Binner S, Nagase H. Steps involved in activation of the complex of pro-matrix metalloproteinase 2 (progelatinase A) and tissue inhibitor of metalloproteinases (TIMP)-2 by 4-aminophenylmercuric acetate. Biochemical Journal 1995, 308(Pt 2):645-651. 1136975, 7772054.
-
(1995)
Biochemical Journal
, vol.308
, Issue.PART 2
, pp. 645-651
-
-
Itoh, Y.1
Binner, S.2
Nagase, H.3
-
3
-
-
45049083085
-
Mapping of macrophage elastase cleavage sites in insoluble human skin elastin
-
10.1016/j.matbio.2008.02.001, 18334288
-
Taddese S, Weiss AS, Neubert RHH, Schmelzer CEH. Mapping of macrophage elastase cleavage sites in insoluble human skin elastin. Matrix Biology 2008, 27(5):420-428. 10.1016/j.matbio.2008.02.001, 18334288.
-
(2008)
Matrix Biology
, vol.27
, Issue.5
, pp. 420-428
-
-
Taddese, S.1
Weiss, A.S.2
Neubert, R.H.H.3
Schmelzer, C.E.H.4
-
4
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
10.1126/science.277.5334.2002, 9302297
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997, 277(5334):2002-2004. 10.1126/science.277.5334.2002, 9302297.
-
(1997)
Science
, vol.277
, Issue.5334
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
5
-
-
0037447184
-
Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. [see comment]
-
Churg A, Wang RD, Tai H, Wang X, Xie C, Dai J, Shapiro SD, Wright JL. Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. [see comment]. American Journal of Respiratory & Critical Care Medicine 2003, 167(8):1083-1089.
-
(2003)
American Journal of Respiratory & Critical Care Medicine
, vol.167
, Issue.8
, pp. 1083-1089
-
-
Churg, A.1
Wang, R.D.2
Tai, H.3
Wang, X.4
Xie, C.5
Dai, J.6
Shapiro, S.D.7
Wright, J.L.8
-
6
-
-
33644643244
-
Elastin fragments drive disease progression in a murine model of emphysema
-
10.1172/JCI25617, 1361346, 16470245
-
Houghton AM, Quintero PA, Perkins DL, Kobayashi DK, Kelley DG, Marconcini LA, Mecham RP, Senior RM, Shapiro SD. Elastin fragments drive disease progression in a murine model of emphysema. Journal of Clinical Investigation 2006, 116(3):753-759. 10.1172/JCI25617, 1361346, 16470245.
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 753-759
-
-
Houghton, A.M.1
Quintero, P.A.2
Perkins, D.L.3
Kobayashi, D.K.4
Kelley, D.G.5
Marconcini, L.A.6
Mecham, R.P.7
Senior, R.M.8
Shapiro, S.D.9
-
7
-
-
34447520043
-
Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
-
10.1038/nrd2308, 17541420
-
Hu J, Van den Steen PE, Sang Q-XA, Opdenakker G. Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases. Nature Reviews. Drug Discovery 2007, 6(6):480-498. 10.1038/nrd2308, 17541420.
-
(2007)
Nature Reviews. Drug Discovery
, vol.6
, Issue.6
, pp. 480-498
-
-
Hu, J.1
Van den Steen, P.E.2
Sang, Q.-.X.A.3
Opdenakker, G.4
-
8
-
-
33645068585
-
Elevated MMP-12 protein levels in induced sputum from patients with COPD
-
10.1136/thx.2005.042432, 2080750, 16308335
-
Demedts IK, Morel-Montero A, Lebecque S, Pacheco Y, Cataldo D, Joos GF, Pauwels RA, Brusselle GG. Elevated MMP-12 protein levels in induced sputum from patients with COPD. Thorax 2006, 61(3):196-201. 10.1136/thx.2005.042432, 2080750, 16308335.
-
(2006)
Thorax
, vol.61
, Issue.3
, pp. 196-201
-
-
Demedts, I.K.1
Morel-Montero, A.2
Lebecque, S.3
Pacheco, Y.4
Cataldo, D.5
Joos, G.F.6
Pauwels, R.A.7
Brusselle, G.G.8
-
9
-
-
0030811544
-
The use of induced sputum to investigate airway inflammation. [see comment]
-
10.1136/thx.52.6.498, 1758588, 9227713
-
Pavord ID, Pizzichini MM, Pizzichini E, Hargreave FE. The use of induced sputum to investigate airway inflammation. [see comment]. Thorax 1997, 52(6):498-501. 10.1136/thx.52.6.498, 1758588, 9227713.
-
(1997)
Thorax
, vol.52
, Issue.6
, pp. 498-501
-
-
Pavord, I.D.1
Pizzichini, M.M.2
Pizzichini, E.3
Hargreave, F.E.4
-
10
-
-
62749084929
-
In vitro degradation of human tropoelastin by MMP-12 and the generation of matrikines from domain 24
-
10.1016/j.matbio.2008.12.002, 19144321
-
Taddese S, Weiss AS, Jahreis G, Neubert RHH, Schmelzer CEH. In vitro degradation of human tropoelastin by MMP-12 and the generation of matrikines from domain 24. Matrix Biology 2009, 28(2):84-91. 10.1016/j.matbio.2008.12.002, 19144321.
-
(2009)
Matrix Biology
, vol.28
, Issue.2
, pp. 84-91
-
-
Taddese, S.1
Weiss, A.S.2
Jahreis, G.3
Neubert, R.H.H.4
Schmelzer, C.E.H.5
-
11
-
-
15244355257
-
Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease
-
10.1007/s00011-004-1319-4, 15723202
-
Molet S, Belleguic C, Lena H, Germain N, Bertrand CP, Shapiro SD, Planquois JM, Delaval P, Lagente V. Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease. Inflamm Res 2005, 54(1):31-36. 10.1007/s00011-004-1319-4, 15723202.
-
(2005)
Inflamm Res
, vol.54
, Issue.1
, pp. 31-36
-
-
Molet, S.1
Belleguic, C.2
Lena, H.3
Germain, N.4
Bertrand, C.P.5
Shapiro, S.D.6
Planquois, J.M.7
Delaval, P.8
Lagente, V.9
-
12
-
-
0027515289
-
Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages
-
Shapiro SD, Kobayashi DK, Ley TJ. Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. Journal of Biological Chemistry 1993, 268(32):23824-23829.
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.32
, pp. 23824-23829
-
-
Shapiro, S.D.1
Kobayashi, D.K.2
Ley, T.J.3
-
13
-
-
15444379857
-
Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia
-
10.1016/j.bbrc.2005.02.144, 15781250
-
Lavigne MC, Eppihimer MJ. Cigarette smoke condensate induces MMP-12 gene expression in airway-like epithelia. Biochem Biophys Res Commun 2005, 330(1):194-203. 10.1016/j.bbrc.2005.02.144, 15781250.
-
(2005)
Biochem Biophys Res Commun
, vol.330
, Issue.1
, pp. 194-203
-
-
Lavigne, M.C.1
Eppihimer, M.J.2
-
14
-
-
5144231839
-
Human bronchial epithelial cells express and secrete MMP-12
-
10.1016/j.bbrc.2004.09.080, 15474460
-
Lavigne MC, Thakker P, Gunn J, Wong A, Miyashiro JS, Wasserman AM, Wei S-Q, Pelker JW, Kobayashi M, Eppihimer MJ. Human bronchial epithelial cells express and secrete MMP-12. Biochem Biophys Res Commun 2004, 324(2):534-546. 10.1016/j.bbrc.2004.09.080, 15474460.
-
(2004)
Biochem Biophys Res Commun
, vol.324
, Issue.2
, pp. 534-546
-
-
Lavigne, M.C.1
Thakker, P.2
Gunn, J.3
Wong, A.4
Miyashiro, J.S.5
Wasserman, A.M.6
Wei, S.-.Q.7
Pelker, J.W.8
Kobayashi, M.9
Eppihimer, M.J.10
-
15
-
-
0036501372
-
The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. [erratum appears in Hum Mol Genet. 2003 Apr 1;12(7):803-4]
-
10.1093/hmg/11.5.569, 11875051
-
Joos L, He J-Q, Shepherdson MB, Connett JE, Anthonisen NR, Pare PD, Sandford AJ. The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. [erratum appears in Hum Mol Genet. 2003 Apr 1;12(7):803-4]. Hum Mol Genet 2002, 11(5):569-576. 10.1093/hmg/11.5.569, 11875051.
-
(2002)
Hum Mol Genet
, vol.11
, Issue.5
, pp. 569-576
-
-
Joos, L.1
He, J.-.Q.2
Shepherdson, M.B.3
Connett, J.E.4
Anthonisen, N.R.5
Pare, P.D.6
Sandford, A.J.7
-
16
-
-
74049134939
-
MMP12, lung function, and COPD in high-risk populations
-
10.1056/NEJMoa0904006, 2904064, 20018959
-
Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melen E, Soderhall C, Hallberg J, et al. MMP12, lung function, and COPD in high-risk populations. New England Journal of Medicine 2009, 361(27):2599-2608. 10.1056/NEJMoa0904006, 2904064, 20018959.
-
(2009)
New England Journal of Medicine
, vol.361
, Issue.27
, pp. 2599-2608
-
-
Hunninghake, G.M.1
Cho, M.H.2
Tesfaigzi, Y.3
Soto-Quiros, M.E.4
Avila, L.5
Lasky-Su, J.6
Stidley, C.7
Melen, E.8
Soderhall, C.9
Hallberg, J.10
-
17
-
-
47249112549
-
The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke
-
10.1038/bjp.2008.180, 2483400, 18493250
-
Le Quement C, Guenon I, Gillon JY, Valenca S, Cayron-Elizondo V, Lagente V, Boichot E. The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke. Br J Pharmacol 2008, 154(6):1206-1215. 10.1038/bjp.2008.180, 2483400, 18493250.
-
(2008)
Br J Pharmacol
, vol.154
, Issue.6
, pp. 1206-1215
-
-
Le Quement, C.1
Guenon, I.2
Gillon, J.Y.3
Valenca, S.4
Cayron-Elizondo, V.5
Lagente, V.6
Boichot, E.7
-
18
-
-
69949090721
-
Identification of an Orally Efficacious Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Asthma
-
10.1021/jm900809r, 19725580
-
Li W, Li J, Wu Y, Rancati F, Vallese S, Raveglia L, Wu J, Hotchandani R, Fuller N, Cunningham K, et al. Identification of an Orally Efficacious Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Asthma. J Med Chem 2009, 52(17):5408-5419. 10.1021/jm900809r, 19725580.
-
(2009)
J Med Chem
, vol.52
, Issue.17
, pp. 5408-5419
-
-
Li, W.1
Li, J.2
Wu, Y.3
Rancati, F.4
Vallese, S.5
Raveglia, L.6
Wu, J.7
Hotchandani, R.8
Fuller, N.9
Cunningham, K.10
-
19
-
-
69949098313
-
The identification of [beta]-hydroxy carboxylic acids as selective MMP-12 inhibitors
-
Holmes IP, Gaines S, Watson SP, Lorthioir O, Walker A, Baddeley SJ, Herbert S, Egan D, Convery MA, Singh OMP, et al. The identification of [beta]-hydroxy carboxylic acids as selective MMP-12 inhibitors. Bioorganic & Medicinal Chemistry Letters 2009, 19(19):5760-5763.
-
(2009)
Bioorganic & Medicinal Chemistry Letters
, vol.19
, Issue.19
, pp. 5760-5763
-
-
Holmes, I.P.1
Gaines, S.2
Watson, S.P.3
Lorthioir, O.4
Walker, A.5
Baddeley, S.J.6
Herbert, S.7
Egan, D.8
Convery, M.A.9
Singh, O.M.P.10
|