GABA B receptor agonism as a novel therapeutic modality in the treatment of gastroesophageal reflux disease

Advances in Pharmacology

Volumn 58, Issue C, 2010, Pages 287-313

  Lehmann, Anders ^a   Jensen, Jörgen M ^a   Boeckxstaens, Guy E ^b  

^a ASTRAZENECA R AND D   (Sweden)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Baclofen; Gastroesophageal reflux disease; Lesogaberan

Indexed keywords

3 AMINO 2 HYDROXYPROPYLPHOSPHINIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; ARBACLOFEN PLACARBIL; AZD 3355; AZD 9343; BACLOFEN; LESOGABERAN; PLACEBO; PROTON PUMP INHIBITOR; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT;

ADD ON THERAPY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CLINICAL TRIAL; CONFUSION; DIZZINESS; DOG; DOSE RESPONSE; DROWSINESS; DRUG ACCUMULATION; DRUG BINDING SITE; DRUG MEGADOSE; DRUG RECEPTOR BINDING; DRUG TRANSPORT; EXHAUSTION; FERRET; GASTROESOPHAGEAL REFLUX; HEADACHE; HUMAN; HYPOTHERMIA; IN VITRO STUDY; IN VIVO CULTURE; INSOMNIA; LASSITUDE; LIGAND BINDING; LOWER ESOPHAGUS SPHINCTER; MORNING DOSAGE; NONHUMAN; PARESTHESIA; PATHOPHYSIOLOGY; PHARMACODYNAMICS; PRIORITY JOURNAL; SEDATION; SIDE EFFECT; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SOMNOLENCE; ANIMAL; CHEMISTRY; DRUG POTENTIATION; DRUG SCREENING; METABOLISM; REVIEW;

ANIMALS; DRUG EVALUATION, PRECLINICAL; GABA AGONISTS; GASTROESOPHAGEAL REFLUX; HUMANS; RECEPTORS, GABA-B;

EID: 77955081953     PISSN: 10543589     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1054-3589(10)58012-8     Document Type: Chapter

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