Relationship between adipokines and periodontitis

Japanese Dental Science Review

Volumn 46, Issue 2, 2010, Pages 159-164

  Furugen, Reiko ^a   Hayashida, Hideaki ^a   Kitamura, Masayasu ^a   Saito, Toshiyuki ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Adipokine; Adiponectin; Inflammation; Leptin; Obesity; Periodontitis; Resistin

Indexed keywords

EID: 77955058046     PISSN: 18827616     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdsr.2010.01.001     Document Type: Review

References (57)

1. Okada H., Murakami S. Cytokine expression in periodontal health and disease. Crit Rev Oral Biol Med 1998, 9:248-266.
2. Southerland J.H., Taylor G.W., Moss K., Beck J.D., Offenbacher S. Commonality in chronic inflammatory diseases: periodontitis, diabetes, and coronary artery disease. Periodontology 2006, 2000(40):130-143.
3. Kopelman P.G. Obesity as a medical problem. Nature 2000, 404:635-643.
4. Saito T., Shimazaki Y., Sakamoto M. Obesity and periodontitis. N Engl J Med 1998, 339:482-483.
5. Pischon N., Heng N., Bernimoulin J.P., Kleber B.M., Willich S.N., Pischon T. Obesity, inflammation, and periodontal disease. J Dent Res 2007, 86:400-409.
6. Saito T., Shimazaki Y. Metabolic disorders related to obesity and periodontal disease. Periodontology 2007, 2000(43):254-266.
7. Shimazaki Y., Saito T., Yonemoto K., Kiyohara Y., Iida M., Yamashita Y. Relationship of metabolic syndrome to periodontal disease in Japanese women: the Hisayama study. J Dent Res 2007, 86:271-275.
8. Saito T., Shimazaki Y., Kiyohara Y., Kato I., Kubo M., Iida M., et al. Relationship between obesity, glucose tolerance, and periodontal disease in Japanese women: the Hisayama study. J Periodontal Res 2005, 40:346-353.
9. Genco R.J., Grossi S.G., Ho A., Nishimura F., Murayama Y. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol 2005, 76:2075-2084.
10. Garlet G.P., Cardoso C.R., Silva T.A., Ferreira B.R., Avila-Campos M.J., Cunha F.Q., et al. Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs RANKL, and their physiological inhibitors. Oral Microbiol Immunol 2006, 21:12-20.
11. Gaffen S.L., Hajishengallis G. A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17. J Dent Res 2008, 87:817-828.
12. Kamio N., Akifusa S., Yamaguchi N., Nonaka K., Yamashita Y. Anti-inflammatory activity of a globular adiponectin function on RAW 264 cells stimulated by lipopolysaccharide from Aggregatibacter actinomycetemcomitans. FEMS Immunol Med Microbiol 2009, 56:241-247.
13. Furugen R., Hayashida H., Yamaguchi N., Yoshihara A., Ogawa H., Miyazaki H., et al. The relationship between periodontal condition and serum levels of resistin and adiponectin in elderly Japanese. J Periodontal Res 2008, 43:556-562.
14. Saito T., Yamaguchi N., Shimazaki Y., Hayashida H., Yonemoto K., Doi Y., et al. Serum levels of resistin and adiponectin in women with periodontitis: the Hisayama study. J Dent Res 2008, 87:319-322.
15. Karthikeyan B.V., Pradeep A.R. Leptin levels in gingival crevicular fluid in periodontal health and disease. J Periodontal Res 2007, 42:300-304.
16. Karthikeyan B.V., Pradeep A.R. Gingival crevicular fluid and serum leptin: their relationship to periodontal health and disease. J Clin Periodontol 2007, 34:467-472.
17. Yamaguchi N., Kukita T., Li Y.J., Martinez Argueta J.G., Saito T., Hanazawa S., et al. Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans. FEMS Immunol Med Microbiol 2007, 49:28-34.
18. Iwamoto Y., Nishimura F., Soga Y., Takeuchi K., Kurihara M., Takashiba S., et al. Antimicrobial periodontal treatment decreases serum C-reactive protein, tumor necrosis factor-alpha, but not adiponectin levels in patients with chronic periodontitis. J Periodontol 2003, 74:1231-1236.
19. Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., Ferrante A.W. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003, 112:1796-1808.
20. Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003, 112:1821-1830.
21. Cancello R., Tordjman J., Poitou C., Guilhem G., Bouillot J.L., Hugol D., et al. Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes 2006, 55:1554-1561.
22. Suganami T., Nishida J., Ogawa Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol 2005, 25:2062-2068.
23. Yamashita A., Soga Y., Iwamoto Y., Yoshizawa S., Iwata H., Kokeguchi S., et al. Macrophage-adipocyte interaction: marked interleukin-6 production by lipopolysaccharide. Obesity (Silver Spring) 2007, 15:2549-2552.
24. Zeyda M., Stulnig T.M. Adipose tissue macrophages. Immunol Lett 2007, 112:61-67.
25. Maeda K., Okubo K., Shimomura I., Funahashi T., Matsuzawa Y., Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1). Biochem Biophys Res Commun 1996, 221:286-289.
26. Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001, 7:941-946.
27. Scherer P.E., Williams S., Fogliano M., Baldini G., Lodish H.F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995, 270:26746-26749.
28. Whitehead J.P., Richards A.A., Hickman I.J., Macdonald G.A., Prins J.B. Adiponectin-a key adipokine in the metabolic syndrome. Diabetes Obes Metab 2006, 8:264-280.
29. Hotta K., Funahashi T., Arita Y., Takahashi M., Matsuda M., Okamoto Y., et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000, 20:1595-1599.
30. Waki H., Yamauchi T., Kamon J., Ito Y., Uchida S., Kita S., et al. Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin. J Biol Chem 2003, 278:40352-40363.
31. Scherer P.E. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 2006, 55:1537-1545.
32. Heidemann C., Sun Q., van Dam R.M., Meigs J.B., Zhang C., Tworoger S.S., et al. Total and high-molecular-weight adiponectin and resistin in relation to the risk for type 2 diabetes in women. Ann Intern Med 2008, 149:307-316.
33. Pajvani U.B., Hawkins M., Combs T.P., Rajala M.W., Doebber T., Berger J.P., et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem 2004, 279:12152-12162.
34. Neumeier M., Weigert J., Schaffler A., Wehrwein G., Muller-Ladner U., Scholmerich J., et al. Different effects of adiponectin isoforms in human monocytic cells. J Leukoc Biol 2006, 79:803-808.
35. Tsatsanis C., Zacharioudaki V., Androulidaki A., Dermitzaki E., Charalampopoulos I., Minas V., et al. Adiponectin induces TNF-alpha and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli. Biochem Biophys Res Commun 2005, 335:1254-1263.
36. Song H., Chan J., Rovin B.H. Induction of chemokine expression by adiponectin in vitro is isoform dependent. Transl Res 2009, 154:18-26.
37. Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995, 95:2409-2415.
38. Kern P.A., Di Gregorio G.B., Lu T., Rassouli N., Ranganathan G. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 2003, 52:1779-1785.
39. Fasshauer M., Paschke R., Stumvoll M. Adiponectin, obesity, and cardiovascular disease. Biochimie 2004, 86:779-784.
40. Yamaguchi N., Argueta J.G., Masuhiro Y., Kagishita M., Nonaka K., Saito T., et al. Adiponectin inhibits toll-like receptor family-induced signaling. FEBS Lett 2005, 579:6821-6826.
41. Considine R.V., Sinha M.K., Heiman M.L., Kriauciunas A., Stephens T.W., Nyce M.R., et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996, 334:292-295.
42. Segal K.R., Landt M., Klein S. Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men. Diabetes 1996, 45:988-991.
43. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature 1994, 372:425-432.
44. Sarraf P., Frederich R.C., Turner E.M., Ma G., Jaskowiak N.T., Rivet D.J., et al. Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J Exp Med 1997, 185:171-175.
45. Bozkurt F.Y., Yetkin Ay Z., Sutcu R., Delibas N., Demirel R. Gingival crevicular fluid leptin levels in periodontitis patients with long-term and heavy smoking. J Periodontol 2006, 77:634-640.
46. Steppan C.M., Bailey S.T., Bhat S., Brown E.J., Banerjee R.R., Wright C.M., et al. The hormone resistin links obesity to diabetes. Nature 2001, 409:307-312.
47. Savage D.B., Sewter C.P., Klenk E.S., Segal D.G., Vidal-Puig A., Considine R.V., et al. Resistin/fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans. Diabetes 2001, 50:2199-2202.
48. Takeishi Y., Niizeki T., Arimoto T., Nozaki N., Hirono O., Nitobe J., et al. Serum resistin is associated with high risk in patients with congestive heart failure-a novel link between metabolic signals and heart failure. Circ J 2007, 71:460-464.
49. Silswal N., Singh A.K., Aruna B., Mukhopadhyay S., Ghosh S., Ehtesham N.Z. Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-κB-dependent pathway. Biochem Biophys Res Commun 2005, 334:1092-1101.
50. Lu S.C., Shieh W.Y., Chen C.Y., Hsu S.C., Chen H.L. Lipopolysaccharide increases resistin gene expression in vivo and in vitro. FEBS Lett 2002, 530:158-162.
51. Lehrke M., Reilly M.P., Millington S.C., Iqbal N., Rader D.J., Lazar M.A. An inflammatory cascade leading to hyperresistinemia in humans. PLoS Med 2004, 1:e45.
52. Thommesen L., Stunes A.K., Monjo M., Grosvik K., Tamburstuen M.V., Kjobli E., et al. Expression and regulation of resistin in osteoblasts and osteoclasts indicate a role in bone metabolism. J Cell Biochem 2006, 99:824-834.
53. Batra A., Pietsch J., Fedke I., Glauben R., Okur B., Stroh T., et al. Leptin-dependent toll-like receptor expression and responsiveness in preadipocytes and adipocytes. Am J Pathol 2007, 170:1931-1941.
54. Shi H., Kokoeva M.V., Inouye K., Tzameli I., Yin H., Flier J.S. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006, 116:3015-3025.
55. Song M.J., Kim K.H., Yoon J.M., Kim J.B. Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochem Biophys Res Commun 2006, 346:739-745.
56. Suganami T., Tanimoto-Koyama K., Nishida J., Itoh M., Yuan X., Mizunami S., et al. Role of the Toll-like receptor 4/NF-κB pathway in saturated fatty acid-induced inflammmatory changes in the interaction between adipocytes and macrophages. Arterioscler Thromb Vasc Biol 2007, 27:84-91.
57. Amar S., Zhou Q., Shaik-Dasthagirisaheb Y., Leeman S. Diet-induced obesity in mice causes changes in immune responses and bone loss manifested by bacterial chalLnge. Proc Natl Acad Sci USA 2007, 104:20466-20471.