Alpinia pricei Hayata rhizome extracts have suppressive and preventive potencies against hypercholesterolemia

Food and Chemical Toxicology

Volumn 48, Issue 8-9, 2010, Pages 2350-2356

  Chang, N W ^a   Wu, C T ^b   Wang, S Y ^c   Pei, R J ^d   Lin, C F ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b FENG YUAN HOSPITAL   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^d JEN AI HOSPITAL   (Taiwan)

Author keywords

Alanine aminotransferase; Alpinia pricei Hayata; Hypercholesterolemia; Peroxisome proliferator activated receptor gamma

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALPINIA PRICEI EXTRACT; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT EXTRACT; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; HYPOCHOLESTEROLEMIC AGENT; LIPOPROTEIN;

ALPINIA; ALPINIA PRICEI; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG MEGADOSE; DRUG POTENCY; ENZYME ACTIVITY; HYPERCHOLESTEROLEMIA; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; NONHUMAN; PROTECTION; PROTEIN EXPRESSION; RHIZOME; SYRIAN HAMSTER; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BLOOD; CHEMISTRY; ENZYMOLOGY; HAMSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER; MESOCRICETUS; METABOLISM;

ALANINE TRANSAMINASE; ALPINIA; ANIMALS; ANTICHOLESTEREMIC AGENTS; BLOTTING, WESTERN; CHOLESTEROL, LDL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; HYPERCHOLESTEROLEMIA; LIPIDS; LIPOPROTEINS; LIVER; MALE; MESOCRICETUS; PLANT EXTRACTS; PPAR GAMMA; RHIZOME; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ALPINIA PRICEI; CRICETINAE; MESOCRICETUS AURATUS;

EID: 77955052369     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.05.070     Document Type: Article

References (45)

1. Ali M.S., Banskota A.H., Tezuka Y., Saiki I., Kadota S. Antiproliferative activity of diarylheptanoids from the seeds of Alpinia blepharocalyx. Biol. Pharm. Bull. 2001, 24:525-528.
2. Arambewela L.S., Arawwawala L.D., Ratnasooriya W.D. Antinociceptive activities of aqueous and ethanolic extracts of Alpinia calcarata rhizomes in rats. J. Ethnopharmacol. 2004, 95:311-316.
3. Bedwell S., Dean R.T., Jessup W. The action of defined oxygen-centred free radicals on human low-density lipoprotein. Biochem. J. 1989, 6:67-75.
4. Bendjeddou D., Lalaoui K., Satta D. Immunostimulating activity of the hot water-soluble polysaccharide extracts of Anacyclus pyrethrum, Alpinia galangal, and Citrullus colocynthis. J. Ethnopharmacol. 2003, 88:155-160.
5. Bogin E., Avidar Y., Merom M. Biochemical changes in liver and blood during liver fattening in rats. J. Clin. Chem. Clin. Biochem. 1986, 24:621-626.
6. Bors W., Heller W., Michel C., Saran M. Flavonoids as antioxidants: determination of radical-scavenging efficiencies. Meth. Enzymol. 1990, 186:343-355.
7. Castelli W.P. Epidemiology of triglycerides: a view from Framingham. Am. J. Cardiol. 1992, 70:H3-H9.
8. Chang N.W., Wu C.T., Chen F.N., Huang P.C. High polyunsaturated and monounsaturated fatty acids to saturated fatty acid ratio increases plasma very low density lipoprotein lipids and reduces the hepatic hypertriglyceridemic effect of dietary cholesterol in rats. Nutr. Res. 2004, 24:73-83.
9. Chen I.N., Chang C.C., Ng C.C., Wang C.Y., Shyu Y.T., Chang T.L. Antioxidant and antimicrobial activity of Zingiberaceae plants in Taiwan. Plant Foods Hum. Nutr. 2008, 63:15-20.
10. Chisolm G.M., Steinberg D. The oxidative modification hypothesis of atherogenesis: an overview. Free Radic. Biol. Med. 2000, 28:1815-1826.
11. Chou Y.C., Wang S.Y., Chen G.C., Lin Y.S., Chao P.M. The functional assessment of Alpinia pricei on metabolic syndrome induced by sucrose-containing drinking water in mice. Phytother. Res. 2009, 23:558-563.
12. 13C NMR spectroscopic analyses. Phytochemistry 2002, 59:429-433.
13. Esterbauer H., Jurgens G., Quehenberger O., Koller E. Autoxidation of human low-density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes. J. Lipid Res. 1987, 28:495-509.
14. Fernandez M.L., Wilson T.A., Conde K., Vergara-Jimenez M., Nicolosi R.J. Hamsters and guinea pigs differ in their plasma lipoprotein cholesterol distribution when fed diets varying in animal protein, soluble fiber, or cholesterol content. J. Nutr. 1999, 129:1323-1332.
15. Griffiths H.R., Moller L., Bartosz G., Bast A., Bertoni-Freddari C., Collins A., Cooke M., Coolen S., Haenen G., Hoberg A.M., Loft S., Lunec J., Olinski R., Parry J., Pompella A., Poulsen H., Verhagen H., Astley S.B. Biomarkers. Molecular Aspects of Medicine 2002, 23:101-208.
16. Israf D.A., Khaizurin T.A., Syahida A., Lajis N.H., Khozirah S. Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells. Mol. Immunol. 2007, 44:673-679.
17. Itabe H., Takeshima E., Iwasaki H., Kimura J., Yoshida Y., Imanaka T., Takano T. A monoclonal antibody against oxidized lipoprotein recognizes foam cells in atherosclerotic lesions. Complex formation of oxidized phosphatidylcholines and polypeptides. J. Biol. Chem. 1994, 269:15274-15279.
18. Iwaki T., Ishizaki K., Kinoshita S., Tanaka H., Fukunari A., Tsurufuji M., Imada T. Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters. World J. Gastroenterol. 2007, 13:5003-5008.
19. Kadota S., Tezuka Y., Prasain J.K., Ali M.S., Banskota A.H. Novel diarylheptanoids of Alpinia blepharocalyx. Curr. Top. Med. Chem. 2003, 3:203-225.
20. Kim M.S., Sweeney T.R., Shigenaga J.K., Chui L.G., Moser A., Grunfeld C., Feingold K.R. Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells. Metabolism 2007, 6:267-279.
21. Knopp R.H., Paramsothy P., Atkinson B., Dowdy A. Comprehensive lipid management versus aggressive low-density lipoprotein lowering to reduce cardiovascular risk. Am. J. Cardiol. 2008, 101:48B-57B.
22. Kopprasch S., Pietzsch J., Kuhlisch E., Fuecker K., Temelkova-Kurktschiev T., Hanefeld M., Kühne H., Julius U., Graessler J. In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance. Diabetes 2002, 51:3102-3106.
23. Korantzopoulos P., Galaris D., Papaioannides D., Siogas K. The possible role of oxidative stress in heart failure and the potential of antioxidant intervention. Med. Sci. Monit. 2003, 9:120-125.
24. Lee C.C., Houghton P. Cytotoxicity of plants from Malaysia and Thailand used traditionally to treat cancer. J. Ethnopharmacol. 2005, 100:237-243.
25. Lin C.T., Senthil Kumar K.J., Tseng Y.H., Wang Z.J., Pan M.Y., Xiao J.H., Chien S.C., Wang S.Y. Anti-inflammatory activity of Flavokawain B from Alpinia pricei Hayata. J. Agric. Food Chem. 2009, 57:6060-6065.
26. Lin L.Y., Peng C.C., Liang Y.J., Yeh W.T., Wang H.E., Yu T.H., Peng R.Y. Alpinia zerumbet potentially elevates high-density lipoprotein cholesterol level in hamsters. J. Agric. Food Chem. 2008, 56:4435-4443.
27. Mead J.R., Ramji D.P. The pivotal role of lipoprotein lipase in atherosclerosis. Cardiovasc. Res. 2002, 55:261-269.
28. Nagy L., Tontonoz P., Alvarez J.G., Chen H., Evans R.M. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 1998, 93:229-240.
29. Ngo K.S., Brown G.D. Stilbenes, monoterpenes, diarylheptanoids, labdanes, and chalcones from Alpinia katsumadai. Phytochemistry 1998, 47:1117-1123.
30. Olszanecki R., Jawień J., Gajda M., Mateuszuk L., Gebska A., Korabiowska M., Chłopicki S., Korbut R. Effect of curcumin on atherosclerosis in apoE/LDLR-double knockout mice. J. Physiol. Pharmacol. 2005, 56:627-635.
31. Plutzky J. Peroxisome proliferator-activated receptors in vascular biology and atherosclerosis: emerging insights for evolving paradigms. Curr. Atheroscler. Rep. 2000, 2:327-335.
32. Ramírez-Tortosa M.C., Mesa M.D., Aguilera M.C., Quiles J.L., Baró L., Ramirez-Tortosa C.L., Martinez-Victoria E., Gil A. Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis. Atherosclerosis 1999, 147:371-378.
33. Sawada M., Matsuo M., Seki J. Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters. Biol. Pharm. Bull. 2002, 25:1577-1582.
34. Schild R.L., Schaiff W.T., Carlson M.G., Cronbach E.G., Nelson D.M., Sadovsky Y. The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids. J. Clin. Endocrinol. Metab. 2002, 87:1105-1110.
35. Sherman K.E. Alanine aminotransferase in clinical practice. A review. Arch. Intern. Med. 1991, 151:260-265.
36. Shi G.F., An L.J., Jiang B., Guan S., Bao Y.M. Alpinia protocatechuic acid protects against oxidative damage in vitro and reduces oxidative stress in vivo. Neurosci. Lett. 2006, 403:206-210.
37. Shin J.E., Han M.J., Song M.C., Baek N.I., Kim D.H. 5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone: a pancreatic lipase inhibitor isolated from Alpinia officinarum. Biol. Pharm. Bull. 2004, 27:138-140.
38. Slatter D.A., Bolton C.H., Bailey A.J. The importance of lipid-derived malondialdehyde in diabetes mellitus. Diabetologia 2000, 43:550-557.
39. Steinberg D. Hypercholesterolemia and inflammation in atherogenesis: two sides of the same coin. Mol. Nutr. Food Res. 2005, 49:995-998.
40. Tontonoz P., Nagy L., Alvarez J.G., Thomazy V.A., Evans R.M. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998, 93:241-252.
41. Twickler T., Dallinga-Thie G.M., Chapman M.J., Cohn J.S. Remnant lipoproteins and atherosclerosis. Curr. Atheroscler. Rep. 2005, 7:140-147.
42. Verhagen H., Aruoma O.I., van Delft J.H., Dragsted L.O., Ferguson L.R., Knasmüller S., Pool-Zobel B.L., Poulsen H.E., Williamson G., Yannai S. The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo. Food Chem. Toxicol. 2003, 41:603-610.
43. Yang H.L., Chen S.C., Chen C.S., Wang S.Y., Hseu Y.C. Alpinia pricei rhizome extracts induce apoptosis of human carcinoma KB cells via a mitochondria-dependent apoptotic pathway. Food Chem.Toxicol. 2008, 46:3318-3324.
44. Wilson T.A., Nicolos R.J., Lawton C.W., Babiak J. Gender differences in response to hypercholesterolemic diet in hamsters: effects on plasma lipoprotein cholesterol concentrations and early aortic atherosclerosis. Atheroscerosis 1999, 146:83-91.
45. Wilson T.A., Nicolosi R.J., Saati A., Kotyla T., Kritchevsky D. Conjugated linoleic acid isomers reduce blood cholesterol levels but not aortic cholesterol accumulation in hypercholesterolemic hamsters. Lipids 2006, 41:41-48.