The future of stem cell transplantation in autoimmune disease

Clinical Reviews in Allergy and Immunology

Volumn 38, Issue 2-3, 2010, Pages 292-297

  Ikehara, Susumu ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Autoimmune disease; Bone marrow transplantation (BMT); Hemopoieticstemcell(HSC); Intra bone marrow (IBM) BMT; Mesenchymalstemcell(MSC)

Indexed keywords

ALLOGENIC BONE MARROW TRANSPLANTATION; AUTOIMMUNE DISEASE; DONOR LYMPHOCYTE INFUSION; EMPHYSEMA; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HEMATOPOIETIC STEM CELL; HUMAN; MALIGNANT NEOPLASTIC DISEASE; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; ORGAN TRANSPLANTATION; OSTEOPOROSIS; REGENERATIVE MEDICINE; REVIEW; SOLID TUMOR; STEM CELL TRANSPLANTATION; STROMA CELL; T CELL DEPLETION;

ANIMALS; AUTOIMMUNE DISEASES; HUMANS; MICE; STEM CELL TRANSPLANTATION;

EID: 77953323431     PISSN: 10800549     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12016-009-8159-5     Document Type: Review

References (38)

1. Ikehara S, Good RA, Nakamura T et al (1985) Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci 82:2483-2487
2. Ikehara S, Ohtsuki H, Good RA et al (1985) Prevention of type I diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation. Proc Natl Acad Sci 82:7743-7747
3. Oyaizu S, Yasumizuy R, Miyama-Inabam M et al (1988) (NZW x BXSB)F1 mouse; a new animal model of idiopathic thrombocytopenic purpura. J Exp Med 167:2017-2022
4. Than SOE, Ishida H, Inaba M et al (1992) Bone marrow transplantation as a strategy for treatment of non-insulin-dependent diabetes mellitus in KK-Ay mice. J Exp Med 176:1233-1238
5. Nishimura M, Toki J, Sugiura K et al (1994) Focal segmental glomerular sclerosis, a type of intractable chronic glomerulonephritis, is a stem cell disorder. J Exp Med 179:1053-1058
6. Ikehara S, Kawamura M, Takao F et al (1990) Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells. Proc Natl Acad Sci 87:8341-8344
7. Kawamura M, Hisha H, Li Y et al (1997) Distinct qualitative differences between normal and abnormal hemopoietic stem cells in vivo and in vitro. Stem Cells 15:56-62
8. Ikehara S (2003) A new concept of stem cell disorders and their new therapy. J. Hematother Stem Cell Res 12:643-653
9. Marmont AM (1994) Immune ablation followed by allogeneic or autologous bone marrow transplantation: a new treatment for severe autoimmune diseases? Stem Cells 12:125-135
10. Ikehara S, Inaba M, Ishida S et al. (1991) Rationale for transplantation of both allogeneic bone marrow and stromal cells in the treatment of autoimmune diseases. In: Champlin RE, Gale RP Eds. New Strategies in Bone Marrow Transplantation UCLA Symposia on Molecular and Cellular Biology, New Series. Wiley-Liss, New York 137:251-257
11. Ishida T, Inaba M, Hisha H et al (1994) Requirement of donorderived stromal cells in the bone marrow for successful allogeneic bone marrow transplantation: complete prevention of recurrence of autoimmune diseases in MRL/MP-lpr/lpr mice by transplantation of bone marrow plus bones (stromal cells) from the same donor. J Immunol 152:3119-3127
12. Kushida T, Inaba M, Takeuchi K et al (2000) Treatment of intractable autoimmune diseases in MRL/lpr mice using a new strategy for allogeneic bone marrow transplantation. Blood 95:1862-1868
13. Kushida T, Inaba M, Hisha H et al (2001) Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice. Blood 97:3292-3299
14. Nakamura T, Good RA, Inoue S et al (2004) Successful liver allografts in mice by combination with allogeneic bone marrow transplantation. Proc Natl Acad Sci U S A 83:4529-4532
15. Ikehara S (2008) A novel method of bone marrow transplantation (BMT) for intractable autoimmune diseases. J Autoimmun 30:108-115
16. Ikebukuro K, Adachi Y, Suzuki Y et al (2006) Synergistic effects of induction in transplantation of allogeneic pancreatic islets. Bone Marrow Transplant 38:657-664
17. Esumi T, Inaba M, Ichioka N et al (2003) Successful allogeneic leg transplantation in rats by combination of intra-bone marrow (IBM) injection of donor bone marrow cells. Transplantation 76:1543-1548
18. Kaneda H, Adachi Y, Saiyo Y et al (2005) Long-term observation after simultaneous lung and intra-bone marrow-bone marrow transplantation. J Heart Lung Transplant 24:1415-1423
19. Guo K, Inaba M, LI M et al (2008) Long-term donor-specific tolerance in rat cardiac allografts by intra-bone marrow injection of donor bone marrow cells. Transplantation 85:93-101
20. Ichioka N, Inaba M, Kushida T et al (2002) Prevention of senile osteoporosis in SAMP6 mice by intra-bone marrow injection of allogeneic bone marrow cells. Stem Cells 20:542-551
21. Takada K, Inaba M, Ichioka N et al (2006) Treatment of senile osteoporosis in SAMP6 mice by intra-bone marrow injection of allogeneic bone marrow cells. Stem Cells 24:399-405
22. Adachi Y, Oyaizu H, Taketani S et al (2006) Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa. Stem Cells 24:2071-2077
23. Thomas ED, Blume KG (1999) Historical markers in the development of allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 5:341-346
24. Weiden PL, Flournoy N, Thomas ED et al (1979) Antileukemic effect of graft-versus-host diseases in human recipients of allogeneic-marrow grafts. N Engl J Med 300:1068-1073
25. Ben-Yosef R, Or R, Nagker A et al (1996) Graft-versus-tumor and graft-versus-leukaemia effect in patient with concurrent breast cancer and acute myelocytic leukaemia. Lancet 348:1242-1243
26. Eibi B, Schwaigofer H, Nachbaur HD et al (1996) Evidence for a graft-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer. Blood 88:1501-1508
27. Ueno NT, Rondon G, Mirza NQ et al (1998) Allogeneic peripheral-blood progenitor-cell transplantation for poor-risk patients with metastatic breast cancer. J Clin Oncol 16:986-993
28. Childs RW, Clave E, Tisdale J et al (1999) Successful treatment of metastatic renal cell carcinoma with a nonmyeloablative allogeneic peripheral-blood progenitor-cell transplant: evidence for a graft-versus-tumor effect. J Clin Oncol 17:2044-2049
29. Childs R, Chernoff A, Contentin N et al (2000) Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med 343:750-758
30. Appelbaum FR, Sandmaier B (2002) Sensitivity of renal cell cancer to nonmyeloablative allogeneic hematopoietic cell transplantation: unusual or unusually important? J Clin Oncol 20: 1965-1967
31. Bregni M, Dodero A, Peccatori J et al (2002) Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer. Blood 99:4234-4236
32. Hentschke P, Barkholt L, Uzunel M et al (2003) Low-intensity conditioning and hematopoietic stem cell transplantation in patients with renal and colon carcinoma. Bone Marrow Transplant 31:253-261
33. Rini BI, Zimmerman T, Stadler WM et al (2002) Allogeneic stem-cell transplantation of renal cell cancer after nonmyeloablative chemotherapy: feasibility, engraftment, and clinical results. J Clin Oncol 20:2017-2024
34. - donor lymphocyte infusion. Stem Cells 23:365-370
35. Koike Y, Adachi Y, Suzuki Y et al (2007) Allogeneic intra-bone marrow-bone marrow transplantation plus donor lymphocyte infusion suppresses growth of colon cancer cells implanted in skin and liver of rats. Stem Cells 25:385-391
36. Inaba M, Adachi Y, Hisha H et al (2007) Extensive studies on perfusion method plus intra-bone marrow-bone marrow transplantation using cynomolgus monkeys. Stem Cells 25:2098-2103
37. Kushida T, Inaba M, Ikebukuro K et al (2002) Comparison of bone marrow cells harvested from various bones of cynomolgus monkeys of various ages by perfusion or aspiration methods: a preclinical study for human BMT. Stem Cells 20:155-162
38. Houghton J, Stoicov C, Nomura S et al (2004) Gastric cancer originating from bone marrow-derived cells. Science 306:1568-1571